Arch Toxicol July 2019 PMID 31123801

Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans.

Eduard Isenmann, Gabriella Ambrosio, Jan Felix Joseph, Monica Mazzarino, Xavier de la Torre, Philipp Zimmer, Rymantas Kazlauskas, Catrin Goebel, Francesco Botrè, Patrick Diel, Maria Kristina Parr

Mentions

137
Peak: 8 in Jun 2019
across 5 sources since May 2019

Extended reach

1,343,279
potential audience

Total likes

13,053

Video views

660,858

Mentions per month

May 2019 – Sep 2025

Where it's discussed

  • News74 articles
  • X / Twitter47 posts
  • YouTube8 videos
  • Facebook5 posts
  • Blogs3 articles

AI synopsis

What people are saying

The group of discussions collectively shows a positive view on the potential performance-enhancing effects of ecdysteroids, with many referencing scientific studies and their own interests in supplements like Turkesterone. The tone balances curiosity, humor, and skepticism, emphasizing the substance's promising results and its possible regulation in sports.

AgreementModerate agreement

Most social discussions support the research showing performance benefits from ecdysteroids, comparing it to natural food sources like spinach and referencing studies with positive muscle gain results.

InterestHigh interest

Several posts express curiosity about the study’s findings, mentioning potential doping implications and seeking advice on supplements, indicating high engagement with the topic.

EngagementModerate engagement

Posts delve into details about specific compounds (like Turkesterone), mention their effects, and refer to research articles, showing active discussion and sharing of information.

ImpactModerate impact

The conversations highlight potential influences on sports regulations and supplement choices, though mostly in a speculative or humorous manner, indicating some impact but not profound societal change.

Abstract in brief

  • Ecdysterone, a natural steroid hormone, may enhance physical performance by binding to estrogen receptors, and recent studies in rats suggest it could be more effective than some banned anabolic agents, but human data is limited.
  • A 10-week study with young men found that those taking ecdysterone supplements showed significant increases in muscle mass and bench press performance, with no signs of liver or kidney toxicity, indicating its potential as a performance enhancer.
  • The research indicates that ecdysterone could deserve consideration for inclusion among prohibited sports substances, similar to anabolic agents, due to its significant performance-enhancing effects observed in human and in vitro studies.]

Top posts

Most liked on X and Bluesky
LORD NEWS BRASIL
@Lordnewsbrasil · X

2️⃣ ECDISTERONA (20-Hydroxyecdysone)

Jun 11, 2025 · 54 likes · 3 shares · 95,629 followers View post →
The Gut Health Doctor | Dr Megan Rossi (RD, PhD)
@TheGutHealthDoc · X

SPINACH

Oct 20, 2019 · 45 likes · 4 shares · 23,578 followers View post →
Bryce Hanna
@photobiogenesis · X

Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans https://t.co/MGoBlsvmld

Mar 26, 2021 · 16 likes · 2 shares · 34,128 followers View post →
Saúl Sánchez
@SaulNutri · X

Jun 3, 2022 · 10 likes · 3 shares · 107,994 followers View post →
Pablo Richly
@PabloRichly · X

Otra buena estrategia publicitaria disfrazada de ciencia. Lean el paper (full accesible en ResearchGate o Sci-Hub) y saquen sus conclusiones. https://t.co/XeuqE8rPjG https://t.co/BkeVLKZguV

Jul 1, 2019 · 9 likes · 2 shares · 6,728 followers View post →
HeightOptimized
@HeightOptimized · X

https://t.co/gLPqsEW0CD

May 27, 2024 · 4 likes · 17,645 followers View post →

All mentions

Thiago Lucas
@Thiago8Crypto · X

RT @Lordnewsbrasil: 2️⃣ ECDISTERONA (20-Hydroxyecdysone)

Jun 11, 2025 · 3 shares · 247 followers View post →
Ana Xerem
@ana_xerem · X

RT @Lordnewsbrasil: 2️⃣ ECDISTERONA (20-Hydroxyecdysone)

Jun 11, 2025 · 3 shares · 416 followers View post →
Gerson Maderi
@GMaderi · X

RT @Lordnewsbrasil: 2️⃣ ECDISTERONA (20-Hydroxyecdysone)

Jun 11, 2025 · 3 shares · 14 followers View post →
LORD NEWS BRASIL
@Lordnewsbrasil · X

2️⃣ ECDISTERONA (20-Hydroxyecdysone)

Jun 11, 2025 · 54 likes · 3 shares · 95,629 followers View post →
DanielSMatthews
@DanielSMatthews · X

@AmandaAskell N.B. This: https://t.co/VnJzjEn9Ge and this: https://t.co/gPX3WFtbUD

May 7, 2025 · 1,621 followers View post →
Lee Stevenson
@bashuser · X

Even though these enhance performance and act similar to an anabolic steroid they can't ban them because they are found in much of our food. https://t.co/lh1Pcjyzdg

Dec 28, 2024 · 1 like · 1,693 followers View post →
HeightOptimized
@HeightOptimized · X

https://t.co/gLPqsEW0CD

May 27, 2024 · 4 likes · 17,645 followers View post →
Solemn Transcendence
@Blue_Ray_9 · X

RT @Blue_Ray_9: @AJA_Cortes https://t.co/T3c4iJOAqX https://t.co/R6ywaKcE3B

Mar 13, 2024 · 1 share · 2,109 followers View post →
Solemn Transcendence
@Blue_Ray_9 · X

@AJA_Cortes https://t.co/T3c4iJOAqX https://t.co/R6ywaKcE3B

Mar 13, 2024 · 1 like · 1 share · 2,109 followers View post →
Sefa Uygun
@sefauygunn · X

Yine bir çalışmada ekdisteron'un androjenik olmadığı teorisi: Ekdisteronların testosteron seviyelerini artırmadığı, ancak yine de güçlü anabolik etkilere sahip olduğunu gösteren takip araştırması tarafından kısmen doğrulanmıştır. https://t.co/GQEzUwjxxS

Aug 2, 2023 · 3 likes · 38,615 followers View post →
Frank Anthony | Peak Performance
@Frankanthony_ · X

@Nutradvance https://t.co/ndjwajz1wY Turkesterone is an ecdysteroid. WADA has been considering adding it to the banned substance list due to how effective it is.

Jun 9, 2023 · 1,290 followers View post →
Nick Norwitz MD PhD
@nicknorwitz · X

@thalesnemo @KenDBerryMD Chitin address above Ecdysteroids steroid hormones found in arthropods , that regulate their development Have been used in sports performance too: https://t.co/54pzPQaH3f "Significantly higher increases in muscle mass were observed in those participants [given] ecdysterone."

Dec 30, 2022 · 1 like · 111,058 followers View post →
MoviesDoe
@MoviesDoe · X

Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans https://t.co/KfqVBt5q2G

Aug 1, 2022 · 1 like · 21,556 followers View post →
Isabel Alonso Troncoso
@IsabelAlonsoTr1 · X

Ecdisterona Con intención de aumentar síntesis endógena de testosterona.... Ecdysteroids: A novel class of anabolic agents?: https://t.co/xvtsJQYS46 Ecdysteroids as non-conventional anabolic agent.. https://t.co/L43AbtMS3Q

Jul 2, 2022 · 670 followers View post →
Cesar C.
@CesarC2084 · X

RT @SaulNutri:

Jun 3, 2022 · 3 shares · 223 followers View post →
MMalaj
@MMalaj1 · X

RT @SaulNutri:

Jun 3, 2022 · 3 shares · 28 followers View post →
Manuel NR.
@ManuelNR2 · X

RT @SaulNutri:

Jun 3, 2022 · 3 shares · 259 followers View post →
Saúl Sánchez
@SaulNutri · X

Jun 3, 2022 · 10 likes · 3 shares · 107,994 followers View post →
Moira
@zkMoira · X

@Steven_McKie Any reason why you chose Turkesterone over Ecdysterone? Trying to formulate my stack now and referencing yours as a starter point https://t.co/JeCIic0akA

Feb 15, 2022 · 1 like · 2,371 followers View post →
I
@IamwhatIeat3 · X

ほeうれん草に含まれるエクジステロンが筋力、筋量を増強する。実験で使われたエクジステロン100mgはほうれん草6kg分。 https://t.co/DP6keRFLQd

Sep 19, 2021 · 2 followers View post →
Saúl Sánchez
@SaulNutri · X

@Manchukk @ivoox Te dejo algo por aquí https://t.co/VyXrYtnYar

Aug 15, 2021 · 2 likes · 107,994 followers View post →
Chuy Garza
@Chuygzaa · X

@BioLayne I've been coming accross a lot of hype, but very little research. This is the only paper I've found. This should make a good Wednesday video (both Turkesterone and Ecdysteroids). Only 10 weeks but "No increase in biomarkers for... toxicity" "https://t.co/6bSraMZQwC

Jul 15, 2021 · 337 followers View post →
Hank Ouspensky
@BrianCooke · X

RT @ck_eternity_: Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans https:…

Mar 26, 2021 · 2 shares · 705 followers View post →
Bryce Hanna
@photobiogenesis · X

Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans https://t.co/MGoBlsvmld

Mar 26, 2021 · 16 likes · 2 shares · 34,128 followers View post →
Bioempower Leaders
@bioempowers · X

Fuente: Isenmann, E., Ambrosio, G., Joseph, J. F., Mazzarino, M., de la Torre, X., Zimmer, P., Kazlauskas, R., Goebel, C., Diel, P. and Parr, M. K. (2019) 'Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans'.

Oct 11, 2020 · 2 likes · 1,483 followers View post →
Satellite Cell Bot
@MuscleStemCell · X

Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans. https://t.co/fBvxmtfNWn

Aug 1, 2020 · 919 followers View post →
Bioemprender
@bioemprenderES · X

Por lo tanto, Popeye el marinero podría ser un gran biólogo encubierto. No tengo pruebas pero tampoco dudas. Fuente: Isenmann et al., 2019 'Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans', Arch Toxicol, 93(7)

Jan 27, 2020 · 1 like · 6,067 followers View post →
DimeComoSea
@DimeComoSea · X

Según el estudio de Monica Mazzarino et al. Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans. Archive für Toxikologie Se necesitan 6.5 kg de espinaca para que se considere dopaje

Jan 2, 2020 · 3,165 followers View post →
The Gut Health Doctor | Dr Megan Rossi (RD, PhD)
@TheGutHealthDoc · X

SPINACH

Oct 20, 2019 · 45 likes · 4 shares · 23,578 followers View post →
POPLINE
@POPLINE_org · X

RT @EurekaMag: Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans https://t.…

Oct 13, 2019 · 2 shares · 5,251 followers View post →
EurekaMag
@EurekaMag · X

Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans https://t.co/eqDjNXw5tn

Oct 13, 2019 · 2 shares · 6,536 followers View post →
Dr. F
@DrF59896059 · X

天然#ステロイドホルモンでホウレンソウにも含まれるエクジステロンとロイシン各100mg併用x2でヒト#10週介入 #筋肉量増加。ポパイも#ドーピング?#スポーツ#文献Isenmann et al. 2019 Ecdysteroids as non-conventional anabolic agent: performance...https://t.co/r99T4Qz885

Jul 26, 2019 · 1 like View post →
1StopSupplements
@1StopSupps · X

Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans https://t.co/dBsEEXFd9q #ecdysterone

Jul 12, 2019 · 111 followers View post →
k
@kaspernilsen · X

RT @Toppform_gym: @strongerbysci Nice! We’re going to get some #Ecdysterone! https://t.co/RtrzYCwuM1 #Muscle #Bodybuilding #Supplements

Jul 11, 2019 · 2 shares · 275 followers View post →
Toppform Oslo
@Toppform_gym · X

RT @Toppform_gym: @strongerbysci Nice! We’re going to get some #Ecdysterone! https://t.co/RtrzYCwuM1 #Muscle #Bodybuilding #Supplements

Jul 11, 2019 · 2 shares · 244 followers View post →
Toppform Oslo
@Toppform_gym · X

@strongerbysci Nice! We’re going to get some #Ecdysterone! https://t.co/RtrzYCwuM1 #Muscle #Bodybuilding #Supplements

Jul 11, 2019 · 4 likes · 2 shares · 244 followers View post →
didaclopez
@didaclopez · X

@gemaesteve L'article publicat a Archives of Toxicology parla específicament de l'ecdisterona i de suplements rics en ecdisterona, i no del consum d'espinacs https://t.co/bSAyrUnuoP

Jul 2, 2019 · 3,440 followers View post →
Pablo Richly
@PabloRichly · X

Otra buena estrategia publicitaria disfrazada de ciencia. Lean el paper (full accesible en ResearchGate o Sci-Hub) y saquen sus conclusiones. https://t.co/XeuqE8rPjG https://t.co/BkeVLKZguV

Jul 1, 2019 · 9 likes · 2 shares · 6,728 followers View post →
Gilles Mengual
@GillesMengual · X

RT @marcriedel_: Ou comment manger des #épinards rends vraiment "plus fort"... Mais pas du tout à cause du fer: l'#ecdysterone contenue à l…

Jun 30, 2019 · 2 shares · 1,478 followers View post →
Martial BX
@Martial_Bx · X

RT @marcriedel_: Ou comment manger des #épinards rends vraiment "plus fort"... Mais pas du tout à cause du fer: l'#ecdysterone contenue à l…

Jun 30, 2019 · 2 shares · 475 followers View post →
Marc Riedel
@marcriedel_ · X

Ou comment manger des #épinards rends vraiment "plus fort"... Mais pas du tout à cause du fer: l'#ecdysterone contenue à l'interieur multiplierait jusqu'à 3x les performances musculaires des participants par rapport à ceux prenant un placebo https://t.co/bEZa9Fis7n https://t.co/1psgjTnRFS

Jun 30, 2019 · 2 likes · 2 shares · 1,465 followers View post →
Čongor Nadj / Nagy Csongor
@CongorN · X

Eating spinach does boost power. Is it a dopping? Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans. - PubMed - NCBI https://t.co/q5zu0Lk3eJ

Jun 28, 2019 · 1 like · 245 followers View post →
Tobias Tiemeier
@T0bbitie · X

@GregNuckols german media covered a recent study examining effects of ecdysterone on strength gains in the bench press a lot in the last days. Results showed 3 times more gains than the placebo over 10 weeks. Your thoughts? https://t.co/R5KApwR5NH

Jun 27, 2019 · 20 followers View post →
Olga Peña PhD.
@OlgaPena · X

RT @marciam: @OlgaPena In other anti-#doping news, there's been some press today on recent WADA-funded research on the performance effect o…

Jun 25, 2019 · 1 share · 3,795 followers View post →
Marcia MacDonald @marcia@spore.social
@marciam · X

@OlgaPena In other anti-#doping news, there's been some press today on recent WADA-funded research on the performance effect of a phytosteroid from spinach extract. Popeye jokes in abundance. Here's the paper from Eduard Isenmann, Maria Kristina Parr, @Botrek et al: https://t.co/iKO5kxU69e

Jun 25, 2019 · 1 like · 1 share · 935 followers View post →
Jordan Older
@JordanOlder_ · X

RT @JordanOlder_: Remember Popeye? Gain 2kg pure muscle in 10 weeks with spinach extract. This spinach extract is banned by sports organi…

Jun 19, 2019 · 1 share · 33,572 followers View post →
Jordan Older
@JordanOlder_ · X

Remember Popeye? Gain 2kg pure muscle in 10 weeks with spinach extract. This spinach extract is banned by sports organizations, so it's not recommended for any competitive athletes. https://t.co/IkxApKn6Zd

May 31, 2019 · 1 like · 1 share · 33,572 followers View post →