Fertil Steril July 2019 PMID 31133384

Effect of GnRH agonist and letrozole treatment in women with recurrent implantation failure.

Naama Steiner, Guy Shrem, Samer Tannus, S Yehuda Dahan, Jacques Balayla, Alexander Volodarsky-Perel, Seang-Lin Tan, Michael H Dahan

Mentions

10
Peak: 6 in May 2019
across 2 sources since May 2019

Extended reach

148,513
potential audience

Total likes

743

Video views

115,461

Mentions per month

May 2019 – Mar 2025

Where it's discussed

  • X / Twitter6 posts
  • YouTube4 videos

AI synopsis

What people are saying

The discussions clearly favor the combination therapy, with many posts highlighting improvements in pregnancy and live birth rates, and some referencing its potential to address endometriosis, using phrases like 'may be superior' and 'potential benefit,' which reflect cautious optimism and suggest the article's moderate impact on ongoing fertility treatment debates.

AgreementModerate agreement

Most discussions acknowledge the positive findings of the study, emphasizing dual suppression therapy's potential benefits in improving fertility outcomes.

InterestHigh interest

Participants show high interest, often discussing the clinical implications and potential advantages of combining GnRH agonist with letrozole, as well as their relevance to endometriosis.

EngagementModerate engagement

Comments feature some depth, referencing mechanisms like endometrial receptivity and personalized treatment, but generally stay within supportive or explanatory tones.

ImpactModerate impact

While the discussion recognizes the possible significance for fertility treatments, there is limited evidence of widespread influence beyond specific patient groups or clinical practices.

Abstract in brief

  • This study examined the effects of combining GnRH agonist and letrozole versus using GnRH agonist alone or no treatment on women with recurrent implantation failure, finding that the combination therapy improved pregnancy and live birth rates.
  • Women treated with both GnRH agonist and letrozole showed higher clinical pregnancy (63%) and live birth rates (56%) compared to those with only GnRH agonist or no pretreatment.
  • The researchers suggest that the improved outcomes may be due to changes in endometrial receptivity or addressing undiagnosed endometriosis, indicating the potential benefit of dual suppression therapy in enhancing fertility success in these women.]

Top posts

Most liked on X and Bluesky
Jacques Balayla MD, MPH
@jacques_balayla · X

Effect of GnRH agonist and letrozole treatment in women with recurrent implantation failure https://t.co/zlvreWmXUw

May 31, 2019 · 3 likes · 725 followers View post →
JorgeLuisSantiF
@JorgeLuisSantiF · X

Effect of GnRH agonist and letrozole treatment in women with recurrent implantation failure https://t.co/fDFNOMbXDT

May 27, 2019 · 2 likes · 1 share · 9,745 followers View post →
JorgeLuisSantiF
@JorgeLuisSantiF · X

Effect of GnRH agonist and letrozole treatment in women with recurrent implantation failure https://t.co/ExHXbvACF6

May 29, 2019 · 1 like · 9,745 followers View post →
JorgeLuisSantiF
@JorgeLuisSantiF · X

Effect of GnRH agonist and letrozole treatment in women with recurrent... https://t.co/KBaTRDkDBS

May 29, 2019 · 1 like · 1 share · 9,745 followers View post →
Max Ezzati, MD
@MaxEzzatiMD · X

Effect of GnRH agonist and letrozole treatment in women with recurrent implantation failure: Dual suppression with GnRH agonist and letrozole may be superior to GnRH agonist-only suppression #endometriosis https://t.co/Q3bCg7BYf5

May 26, 2019 · 1 like · 1,986 followers View post →
Franco Lisi fecondazione assistita Roma
@FrancoLisi · X

Effect of GnRH agonist and letrozole treatment in women with recurrent implantation failure https://t.co/Mt44PosDHW

May 24, 2019 · 1,103 followers View post →

All mentions

Jacques Balayla MD, MPH
@jacques_balayla · X

Effect of GnRH agonist and letrozole treatment in women with recurrent implantation failure https://t.co/zlvreWmXUw

May 31, 2019 · 3 likes · 725 followers View post →
JorgeLuisSantiF
@JorgeLuisSantiF · X

Effect of GnRH agonist and letrozole treatment in women with recurrent implantation failure https://t.co/ExHXbvACF6

May 29, 2019 · 1 like · 9,745 followers View post →
JorgeLuisSantiF
@JorgeLuisSantiF · X

Effect of GnRH agonist and letrozole treatment in women with recurrent... https://t.co/KBaTRDkDBS

May 29, 2019 · 1 like · 1 share · 9,745 followers View post →
JorgeLuisSantiF
@JorgeLuisSantiF · X

Effect of GnRH agonist and letrozole treatment in women with recurrent implantation failure https://t.co/fDFNOMbXDT

May 27, 2019 · 2 likes · 1 share · 9,745 followers View post →
Max Ezzati, MD
@MaxEzzatiMD · X

Effect of GnRH agonist and letrozole treatment in women with recurrent implantation failure: Dual suppression with GnRH agonist and letrozole may be superior to GnRH agonist-only suppression #endometriosis https://t.co/Q3bCg7BYf5

May 26, 2019 · 1 like · 1,986 followers View post →
Franco Lisi fecondazione assistita Roma
@FrancoLisi · X

Effect of GnRH agonist and letrozole treatment in women with recurrent implantation failure https://t.co/Mt44PosDHW

May 24, 2019 · 1,103 followers View post →