Nutrients May 2019 PMID 31141915

Hydration, Arginine Vasopressin, and Glucoregulatory Health in Humans: A Critical Perspective.

Harriet A Carroll, Lewis J James

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Mentions

25
Peak: 3 in Jan 2020
across 3 sources since May 2019

Extended reach

173,742
potential audience

Total likes

969

Video views

23,397

Mentions per month

May 2019 – Dec 2025

Where it's discussed

  • X / Twitter22 posts
  • YouTube2 videos
  • Instagram1 posts

AI synopsis

What people are saying

The discussions show a nuanced perspective, with users referencing experimental findings, such as null results from research, to question traditional views that dehydration causes blood sugar dysregulation, and they use lively examples like ecstasy's effects to challenge or expand current understanding. The tone combines scientific critique with curiosity, reflecting active engagement and an interest in advancing the field.

AgreementModerate agreement

Most discussions acknowledge the complexity of hydration and AVP's role in blood sugar regulation, with some highlighting that manipulating hydration may not improve glucoregulatory health, thus showing partial agreement with the article's cautious stance

InterestHigh interest

The tweets demonstrate high interest, evidenced by references to new research, personal studies, and innovative ideas such as using ecstasy as a model to understand AVP's effects.

EngagementModerate engagement

Participants actively critique previous assumptions, share their research experiences, and discuss the implications, indicating moderate engagement.

ImpactModerate impact

Debates surrounding the validity of existing theories and the potential for new models suggest a modest but meaningful impact in challenging prevailing ideas in hydration research.

Abstract in brief

  • The article reviews the role of water intake and arginine vasopressin (AVP) in regulating blood sugar levels, highlighting that current dietary guidelines promoting water consumption are not based on direct causal evidence but rather on mechanistic data and observational studies.
  • Historically, research in the 1970s and 1980s linked elevated AVP levels to blood sugar regulation, but interest in this area waned until recent decades, when new types of studies, including human hydration manipulations, revived the investigation into AVP’s role in glucoregulation.
  • The authors suggest that while AVP may influence blood sugar control, evidence from more realistic human studies indicates this effect could be independent of hydration status itself, implying that simply increasing water intake to lower AVP might not necessarily improve glucoregulatory health.]

Top posts

Most liked on X and Bluesky
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

First theory paper now published! Very excited to get this out as its a culmination of lots of theories ive had brewing over the last few years about the influence of AVP, #hydration status, & #glucose regulation... 1/9 #Health #diabetes #metabolism #water https://t.co/N7LkJvOgW5 https://t.co/jBkvKoEbC2

May 28, 2019 · 23 likes · 4 shares · 8,810 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

Fun fact: ecstasy (the party drug) gives all the *symptoms* of DEhydration, when on a cellular level it cause OVERhydration. as such, it can be useful to understand the independent effects of certain systems: https://t.co/N7LkJvOgW5 easy to read summary: https://t.co/b9BzORFY8z

Dec 2, 2020 · 14 likes · 8 shares · 8,810 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

Here is an example: my PhD found null findings in one of my studies. This offered the opportunity to explore the validity of the prior research and its underpinning ideas on the topic. If we try to ignore these results, we fail to progress https://t.co/QYKwvHA7gi

Feb 16, 2023 · 10 likes · 8,810 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

@Saltykid41 @Mae522018 Yes it does. Heres an example: the way me and my colleague read the literature came to a vastly different conclusion to most others. Both perspectives are data driven expert opinion https://t.co/QYKwvHA7gi

Sep 23, 2022 · 3 likes · 8,810 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

And it also adds weight to me and Lewis' hypothesis that "manipulating hydration status to reduce circulating AVP concentrations may not be an effective method to improve glucoregulatory health" https://t.co/N7LkJvOOLD

Mar 21, 2025 · 2 likes · 8,810 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

2. Our opinion on current theories relating to AVP, hydration and glucoregulation. Including how we can use #ecstacy as a model to uncouple AVP and hydration https://t.co/N7LkJvOgW5 #H4H2019 #hydration #Health #mdma 2/2

Jun 26, 2019 · 1 like · 8,810 followers View post →

All mentions

Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

RT @angryhacademic: Fun fact: ecstasy (the party drug) gives all the *symptoms* of DEhydration, when on a cellular level it cause OVERhydra…

Dec 2, 2025 · 8 shares · 8,810 followers View post →
YO PEEP GAME!
@YDWYPG · X

RT @angryhacademic: Fun fact: ecstasy (the party drug) gives all the *symptoms* of DEhydration, when on a cellular level it cause OVERhydra…

May 28, 2025 · 8 shares · 2,383 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

And it also adds weight to me and Lewis' hypothesis that "manipulating hydration status to reduce circulating AVP concentrations may not be an effective method to improve glucoregulatory health" https://t.co/N7LkJvOOLD

Mar 21, 2025 · 2 likes · 8,810 followers View post →
rachel
@shadowboxer73 · X

RT @angryhacademic: Fun fact: ecstasy (the party drug) gives all the *symptoms* of DEhydration, when on a cellular level it cause OVERhydra…

Dec 2, 2024 · 8 shares · 1,997 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

RT @angryhacademic: Fun fact: ecstasy (the party drug) gives all the *symptoms* of DEhydration, when on a cellular level it cause OVERhydra…

Dec 2, 2024 · 8 shares · 8,810 followers View post →
Alex
@softminus · X

RT @angryhacademic: Fun fact: ecstasy (the party drug) gives all the *symptoms* of DEhydration, when on a cellular level it cause OVERhydra…

Dec 1, 2023 · 8 shares · 10,096 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

RT @angryhacademic: Fun fact: ecstasy (the party drug) gives all the *symptoms* of DEhydration, when on a cellular level it cause OVERhydra…

Dec 1, 2023 · 8 shares · 8,810 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

Here is an example: my PhD found null findings in one of my studies. This offered the opportunity to explore the validity of the prior research and its underpinning ideas on the topic. If we try to ignore these results, we fail to progress https://t.co/QYKwvHA7gi

Feb 16, 2023 · 10 likes · 8,810 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

RT @angryhacademic: Fun fact: ecstasy (the party drug) gives all the *symptoms* of DEhydration, when on a cellular level it cause OVERhydra…

Dec 2, 2022 · 8 shares · 8,810 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

@Saltykid41 @Mae522018 Yes it does. Heres an example: the way me and my colleague read the literature came to a vastly different conclusion to most others. Both perspectives are data driven expert opinion https://t.co/QYKwvHA7gi

Sep 23, 2022 · 3 likes · 8,810 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

3. academically in my field (hydration), the current party line to tow is that dehydration causes blood sugar dysregulation. i based 2 masters degrees & a PhD on this idea. here i am disagreeing with that as new data suggested to me that the idea was wrong https://t.co/QYKwvHA7gi

Mar 12, 2022 · 8,810 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

RT @angryhacademic: Fun fact: ecstasy (the party drug) gives all the *symptoms* of DEhydration, when on a cellular level it cause OVERhydra…

Dec 2, 2021 · 8 shares · 8,810 followers View post →
AKA_Sadrien
@AKA_Sadrien · X

@angryhacademic https://t.co/4D71iakX1W for example?

May 18, 2021 · 789 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

Fun fact: ecstasy (the party drug) gives all the *symptoms* of DEhydration, when on a cellular level it cause OVERhydration. as such, it can be useful to understand the independent effects of certain systems: https://t.co/N7LkJvOgW5 easy to read summary: https://t.co/b9BzORFY8z

Dec 2, 2020 · 14 likes · 8 shares · 8,810 followers View post →
CREEB Roehampton
@CREEBroehampton · X

RT @angryhacademic: First theory paper now published! Very excited to get this out as its a culmination of lots of theories ive had brewing…

Mar 25, 2020 · 4 shares · 708 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

@JonDavidAdams @USARIEM Cant access the full text on my phone. Sounds v interesting though We also touched on the pitfalls on AVP as a hydration biomarker in our perspective piece. Imo we need to distinguish total body water (hydration status) & hydration physiology a bit better https://t.co/N7LkJvwFxv

Jan 25, 2020 · 8,810 followers View post →
William Adams, PhD, ATC, FACSM
@william_m_adams · X

RT @angryhacademic: First theory paper now published! Very excited to get this out as its a culmination of lots of theories ive had brewing…

Jan 16, 2020 · 4 shares · 1,653 followers View post →
HEATStressLab
@HEATStressLab · X

RT @angryhacademic: First theory paper now published! Very excited to get this out as its a culmination of lots of theories ive had brewing…

Jan 16, 2020 · 4 shares · 384 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

Question from the audience about #diabetes insipidus - something we discuss in our persepctive piece: https://t.co/N7LkJvOgW5 #H4H2019 #hydration #Health

Jun 26, 2019 · 8,810 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

2. Our opinion on current theories relating to AVP, hydration and glucoregulation. Including how we can use #ecstacy as a model to uncouple AVP and hydration https://t.co/N7LkJvOgW5 #H4H2019 #hydration #Health #mdma 2/2

Jun 26, 2019 · 1 like · 8,810 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

@MatthewJDalby Yeah sorry that got hidden a bit in the first tweet! https://t.co/N7LkJvOgW5

May 28, 2019 · 1 like · 8,810 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

First theory paper now published! Very excited to get this out as its a culmination of lots of theories ive had brewing over the last few years about the influence of AVP, #hydration status, & #glucose regulation... 1/9 #Health #diabetes #metabolism #water https://t.co/N7LkJvOgW5 https://t.co/jBkvKoEbC2

May 28, 2019 · 23 likes · 4 shares · 8,810 followers View post →
Blood sugar highs can be influenced by hydration. Low fluid intake ...
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... 10.3390/nu11061201. PMID: 31141915; PMCID: PMC6627358.) I personally wonder if the "dawn effect" seen in Type II diabetes where the glucose ...

Sep 17, 2021 View →