Nat Ecol Evol July 2019 PMID 31182815

Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats.

Zixia Huang, Conor V Whelan, Nicole M Foley, David Jebb, Frédéric Touzalin, Eric J Petit, Sébastien J Puechmaille, Emma C Teeling

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Peak: 46 in Jun 2019

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The group shows strong agreement and keen interest, as evidenced by comments praising the research as a 'good start' and 'noting its significance,' often emphasizing the longitudinal approach and unique mechanisms uncovered, reflecting substantial engagement and recognition of potential impact.

AgreementModerate agreement

Most discussions express a positive view of the study, highlighting its novelty and importance, indicating general support for its findings.

InterestHigh interest

Discussion shows high interest, with many posters emphasizing the significance of the research and its potential implications for aging and longevity.

EngagementModerate engagement

Posts include specific references to longitudinal analysis, unique mechanisms, and microRNA findings, reflecting active engagement with the research details.

ImpactModerate impact

Shared content highlights the study's importance in advancing understanding of mammalian longevity, suggesting a moderate but meaningful perceived impact.

Abstract in brief

This study conducted an eight-year longitudinal analysis of gene expression in long-lived bats (Myotis myotis) to understand the molecular mechanisms behind their extended healthspan.
Unlike humans and other mammals, bats show unique gene expression patterns related to DNA repair, autophagy, immunity, and tumor suppression, which may contribute to their longevity.
The research also identified specific microRNAs that regulate these aging-related genes, offering potential targets for future aging interventions and deeper insights into the biological processes that promote healthy aging in mammals.

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David Hayman

@dtsh2 · X

RT @teague_o: @DavidQuammen @batgirl_susan @John_F_Taylor This is a good start: Longitudinal comparative transcriptomics reveals unique mec…

Jul 29, 2019 · 1 share · 1,274 followers View post →

Teague O'Mara

@teague_o · X

@DavidQuammen @batgirl_susan @John_F_Taylor This is a good start: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/U9TfJCi6SE

Jul 29, 2019 · 3 likes · 1 share · 1,426 followers View post →

Bat1k Genome Project

@bat1kgenomes · X

RT @GenomeBiolEvol: Zixia Huang (@ZixiaH) from @BatLabUCD performed longitudinal transcriptomics in bats, the longest-lived mammals by body…

Jul 24, 2019 · 5 shares · 2,571 followers View post →

Yolanda Espinosa Parrilla

@SuoriYol · X

RT @GenomeBiolEvol: Zixia Huang (@ZixiaH) from @BatLabUCD performed longitudinal transcriptomics in bats, the longest-lived mammals by body…

Jul 23, 2019 · 5 shares · 22 followers View post →

David Jebb

@jebb_david · X

RT @GenomeBiolEvol: Zixia Huang (@ZixiaH) from @BatLabUCD performed longitudinal transcriptomics in bats, the longest-lived mammals by body…

Jul 23, 2019 · 5 shares · 231 followers View post →

Darren O'Connell

@Dar_OConnell · X

RT @GenomeBiolEvol: Zixia Huang (@ZixiaH) from @BatLabUCD performed longitudinal transcriptomics in bats, the longest-lived mammals by body…

Jul 23, 2019 · 5 shares · 689 followers View post →

Yue Hao 郝樾

@yue_hao · X

RT @GenomeBiolEvol: Zixia Huang (@ZixiaH) from @BatLabUCD performed longitudinal transcriptomics in bats, the longest-lived mammals by body…

Jul 23, 2019 · 5 shares · 398 followers View post →

マグネット2号機

@magnet2nd · X

【論文メモ】非常に長寿(41年以上)なコウモリの血液トランスクリプトーム比較。0~7歳以上の各年齢のコウモリの発現量を解析。最も多く発現していた遺伝子上位100位の発現量は全トランスクリプトーム量の75%以上を占め、オートファジーやDNA修復にかかわる遺伝子が見つかった。https://t.co/HkDpi6Gp0y

Jul 10, 2019 · 19 followers View post →

LongevityHub

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Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats - https://t.co/zg0Lx5WoL2 - #longevity #health

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Trump Brain Worm

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RT @BarbastellaJ: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/H5…

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Margaret Bryer

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RT @BarbastellaJ: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/nk…

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Michelle Wille

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Daniel Becker

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RT @BarbastellaJ: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/nk…

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Lizzie Platt

@HenlakeBats · X

RT @BarbastellaJ: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/nk…

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Journal of Bat Research & Conservation

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Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/nkrXfsGc3Y

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Martin Denzel

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RT @MyAgeGroup: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats | Nature Ecology…

Jun 28, 2019 · 2 shares · 2,902 followers View post →

Bérénice A. Benayoun, PhD

@BBParis1984 · X

RT @MyAgeGroup: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats | Nature Ecology…

Jun 28, 2019 · 2 shares · 3,425 followers View post →

MyAgeGroup

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Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats | Nature Ecology & Evolution. BB. https://t.co/uz6XXWcoMy

Jun 28, 2019 · 4 likes · 2 shares · 1,547 followers View post →

Bérénice A. Benayoun, PhD

@BBParis1984 · X

RT @Prof_M_Ristow: Longitudinal comparative #transcriptomics reveals unique mechanisms underlying extended #healthspan in long-lived #bat-s…

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Jim Johnson, PhD

@JimJohnsonSci · X

RT @Prof_M_Ristow: Longitudinal comparative #transcriptomics reveals unique mechanisms underlying extended #healthspan in long-lived #bat-s…

Jun 28, 2019 · 2 shares · 12,841 followers View post →

Michael Ristow, MD

@Prof_M_Ristow · X

Longitudinal comparative #transcriptomics reveals unique mechanisms underlying extended #healthspan in long-lived #bat-s. https://t.co/ZfgSxAVyTm

Jun 28, 2019 · 9 likes · 2 shares · 6,981 followers View post →

Bioinfo - MRD

@BioinfoULA · X

RT @BatResearch: kudos to @EmmaTeeling1 for a nice paper. Longitudinal comparative transcriptomics reveals unique mechanisms underlying ext…

Jun 18, 2019 · 1 share · 728 followers View post →

E. Yağmur Erten

@yagmur_erten · X

47/ #365papers "Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats", Huang et al. 2019 https://t.co/RWpeL6dNF2

Jun 18, 2019 · 1,301 followers View post →

Celia P. Martinez-Jimenez

@celia4science · X

RT @AgingBiology: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/vQ…

Jun 16, 2019 · 5 shares · 396 followers View post →

annibal_ms

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RT @AgingBiology: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/vQ…

Jun 14, 2019 · 5 shares · 304 followers View post →

Jake

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RT @AgingBiology: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/vQ…

Jun 14, 2019 · 5 shares · 55 followers View post →

Julia B.

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RT @AgingBiology: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/vQ…

Jun 13, 2019 · 5 shares · 2,259 followers View post →

Aging Science News

@AgingBiology · X

Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/vQmD85lPSr

Jun 13, 2019 · 12 likes · 5 shares · 31,387 followers View post →

Daniel Becker

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RT @batpapers: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats. https://t.co/L4eY…

Jun 12, 2019 · 1 share · 3,179 followers View post →

Bat_papers

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Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats. https://t.co/L4eYJXW5h8

Jun 12, 2019 · 1 share · 1,250 followers View post →

Darren O'Connell

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RT @BatLabUCD: https://t.co/5jVrokWQ72

Jun 12, 2019 · 2 shares · 689 followers View post →

Physical Geography BHARATVARSH

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Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats | Nature Ecology & Evolution https://t.co/eP0VydYrKc

Jun 12, 2019 · 1 like · 1,053 followers View post →

Kathe Chacon

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RT @NatureEcoEvo: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/hN…

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ScienceForAll

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RT @EvolPaper: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/S4PMv…

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Evolutionary Genomics

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Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/S4PMvXpRWK @NatureEcoEvo

Jun 12, 2019 · 3 likes · 2 shares · 5,057 followers View post →

Kevin Mitchell

@WiringTheBrain · X

RT @robertclab: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/eR02…

Jun 12, 2019 · 1 share · 40,450 followers View post →

Robert Castelo

@robertclab · X

Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/eR02pCkPvW by the lab of @EmmaTeeling1

Jun 12, 2019 · 4 likes · 1 share · 919 followers View post →

Neil Gemmell

@ProfGemmell · X

RT @NatureEcoEvo: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/hN…

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NatureEcoEvo

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RT @NatureEcoEvo: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/hN…

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Nonia Pariente

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RT @NatureEcoEvo: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/hN…

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Alexander Suh 서상재

@alexander_suh · X

RT @NatureEcoEvo: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/hN…

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Kiyotaka Yabe

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Taki Kawakami

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RT @NatureEcoEvo: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/hN…

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NatureEcoEvo

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Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/hNcRQONoDN https://t.co/SnOyUjmiab

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Edward Hurme

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RT @BarbastellaJ: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/H5…

Jun 11, 2019 · 8 shares · 1,112 followers View post →

David Hayman

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RT @BarbastellaJ: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/H5…

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UCD Science

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RT @BatLabUCD: https://t.co/5jVrokWQ72

Jun 11, 2019 · 2 shares · 9,077 followers View post →

Bat Researcher - A.Prof. Aaron Irving

@BatResearch · X

kudos to @EmmaTeeling1 for a nice paper. Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats Nature Ecology & Evolution (2019) 10.6.19 https://t.co/LapWse3Tn4

Jun 10, 2019 · 1 share · 2,525 followers View post →

Josep Vidal O+

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RT @BarbastellaJ: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/H5…

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Marcel A. Muller

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RT @BarbastellaJ: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/H5…

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Teague O'Mara

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RT @BarbastellaJ: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/H5…

Jun 10, 2019 · 8 shares · 1,426 followers View post →

Attila D. Sandor

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RT @BarbastellaJ: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/H5…

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Daniel Becker

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RT @BarbastellaJ: Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/H5…

Jun 10, 2019 · 8 shares · 3,179 followers View post →

Journal of Bat Research & Conservation

@BarbastellaJ · X

Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats https://t.co/H5VnqA7N1b @NatureEcoEvo

Jun 10, 2019 · 17 likes · 8 shares · 4,551 followers View post →

UCD BatLab

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Jun 10, 2019 · 4 likes · 2 shares · 1,534 followers View post →

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Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Bats and Longevity: Insights into Healthy Aging and Immune Adaptations

Bats' Unique Longevity and Immune Systems Explored