Birth Defects Res October 2019 PMID 31197966

Trichloroethylene in drinking water throughout gestation did not produce congenital heart defects in Sprague Dawley rats.

John M DeSesso, Prägati S Coder, Raymond G York, Robert A Budinsky, Lynn H Pottenger, Shiladitya Sen, Joelle M Lucarell, Christopher Bevan, James S Bus

Mentions

10
Peak: 2 in Apr 2020
across 4 sources since Feb 2020

Extended reach

1,596
potential audience

Total likes

24

Video views

531

Mentions per month

Feb 2020 – Jun 2024

Where it's discussed

  • News6 articles
  • YouTube2 videos
  • X / Twitter1 posts
  • Blogs1 articles

AI synopsis

What people are saying

Many posts show a balanced tone, pointing out contradictions in animal studies and discussing the relevance of these findings with phrases like 'highlights apparent contradictions' and questioning 'study results.' The tone suggests a cautious curiosity, reflecting interest and engagement but not full consensus or high impact, based on the language used to analyze the study's implications.

AgreementModerate agreement

Most discussions acknowledge the study's findings, with some posts expressing support or tentative agreement, but not unanimously affirming strong concurrence.

InterestModerate interest

Participants seem moderately interested, as they raise questions or highlight contradictions without deep dives into implications.

EngagementModerate engagement

Comments include references to contradictions and discussions about study design, indicating a reasonable level of active engagement.

ImpactNeutral impact

The overall impact appears limited, with some noting the study's implications for understanding TCE safety but not suggesting a major societal shift.

Abstract in brief

  • The study examined whether consuming trichloroethylene (TCE) in drinking water during pregnancy causes heart defects in rats and found no evidence of such defects at a high dose of 1000 ppm.
  • While higher doses of TCE reduced water intake slightly, there were no significant effects on maternal or fetal weights, and the only fetal heart anomaly observed was a common, minor ventricular septal defect also seen in control groups.
  • The research confirmed that pregnant rats were systemically exposed to TCE (via its metabolite, trichloroacetic acid), but TCE ingestion at 1000 ppm throughout gestation did not result in increased congenital heart defects in their offspring.]

Top posts

Most liked on X and Bluesky
Michael Stiles
@southernmike1 · X

@drdavidmichaels @g_coudray @reveal @ShogrenE Sprague Dawley rats study highlights apparent contradictions in animal Trichloroethylene (TCE) studies. https://t.co/JYf5jjzNBt https://t.co/FreuXnxm5U

Feb 29, 2020 · 996 followers View post →

All mentions

Michael Stiles
@southernmike1 · X

@drdavidmichaels @g_coudray @reveal @ShogrenE Sprague Dawley rats study highlights apparent contradictions in animal Trichloroethylene (TCE) studies. https://t.co/JYf5jjzNBt https://t.co/FreuXnxm5U

Feb 29, 2020 · 996 followers View post →
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