June 2019 PMID 31215466

miR-34a promotes bone regeneration in irradiated bone defects by enhancing osteoblastic differentiation of mesenchymal stromal cells in rats.

Huan Liu, Yan Dong, Xiaoke Feng, Liya Li, Yang Jiao, Shizhu Bai, Zhihong Feng, Hao Yu, Xuejian Li, Yimin Zhao

Mentions

10
Peak: 2 in Jun 2019
across 4 sources since Jun 2019

Extended reach

17,573
potential audience

Total likes

4

Video views

513

Mentions per month

Jun 2019 – May 2022

Where it's discussed

  • X / Twitter4 posts
  • YouTube2 videos
  • Facebook2 posts
  • News2 articles

AI synopsis

What people are saying

The overall tone indicates strong interest and agreement, with comments referencing the significance of miR-34a in enhancing bone regeneration, and terms like 'promotes' and 'potential' highlight optimism about the research’s implications. The use of technical terms such as 'osteoblastic differentiation' and hashtags like #BoneScienceNews reflects active engagement and recognition of the study's relevance in the field.

AgreementModerate agreement

Most discussions express approval and recognition of miR-34a's positive role in bone healing, indicating general agreement with the publication's findings.

InterestHigh interest

The discussions demonstrate high interest, referring to the research as promising and highlighting its potential clinical implications.

EngagementModerate engagement

Participants engage by sharing related hashtags, summarizing the study's significance, and referencing specific processes like osteoblastic differentiation.

ImpactModerate impact

Some comments hint at potential impacts on bone regenerative therapies and future research directions, suggesting moderate perceived importance.

Abstract in brief

  • Radiation exposure hampers bone healing, making recovery from bone defects after tumor removal difficult.
  • The study explored miR-34a's role in aiding bone regeneration in irradiated areas by analyzing its expression in bone marrow stem cells and their differentiation under radiation.
  • Results showed that increasing miR-34a levels improved bone cell differentiation and healed bone defects in rat models, suggesting that targeting miR-34a could be a useful strategy in post-radiation bone recovery.

Top posts

Most liked on X and Bluesky
ASBMR
@ASBMR · X

miR-34a promotes bone regeneration in irradiated bone defects by enhancing osteoblastic differentiation of mesenchymal stromal cells in rats #BoneScienceNews https://t.co/4miexi0wRK

Jun 30, 2019 · 1 like · 1 share · 6,016 followers View post →
Boster Bio
@BosterbioCo · X

Learn ALPL in 3 Minutes https://t.co/oZepe0ZsMm. P.S- If you cannot find antibodies that fit your needs, contact us TODAY ! We have a full suite of custom antibody services covering research to diagnostic and therapeutic applications.

May 5, 2022 · 7,983 followers View post →
Dr Ritu Trivedi, डा ऋतु त्रिवेदी
@ritu_trivedi · X

RT @ASBMR: miR-34a promotes bone regeneration in irradiated bone defects by enhancing osteoblastic differentiation of mesenchymal stromal c…

Jun 30, 2019 · 1 share · 1,802 followers View post →
@RadOncPapers
@radoncpapers · X

miR-34a promotes bone regeneration in irradiated bone defects by enhancing osteoblastic differentiation of mesenchymal stromal cells in rats. https://t.co/FbJB2X9cRP H/T @NCBI #radonc #PubMed https://t.co/joqhYPaHJ7

Jul 1, 2020 · 1,256 followers View post →

All mentions

Boster Bio
@BosterbioCo · X

Learn ALPL in 3 Minutes https://t.co/oZepe0ZsMm. P.S- If you cannot find antibodies that fit your needs, contact us TODAY ! We have a full suite of custom antibody services covering research to diagnostic and therapeutic applications.

May 5, 2022 · 7,983 followers View post →
@RadOncPapers
@radoncpapers · X

miR-34a promotes bone regeneration in irradiated bone defects by enhancing osteoblastic differentiation of mesenchymal stromal cells in rats. https://t.co/FbJB2X9cRP H/T @NCBI #radonc #PubMed https://t.co/joqhYPaHJ7

Jul 1, 2020 · 1,256 followers View post →
Dr Ritu Trivedi, डा ऋतु त्रिवेदी
@ritu_trivedi · X

RT @ASBMR: miR-34a promotes bone regeneration in irradiated bone defects by enhancing osteoblastic differentiation of mesenchymal stromal c…

Jun 30, 2019 · 1 share · 1,802 followers View post →
ASBMR
@ASBMR · X

miR-34a promotes bone regeneration in irradiated bone defects by enhancing osteoblastic differentiation of mesenchymal stromal cells in rats #BoneScienceNews https://t.co/4miexi0wRK

Jun 30, 2019 · 1 like · 1 share · 6,016 followers View post →