Psychol Med September 2019 PMID 31258105

Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels.

Emanuele Felice Osimo, Luke James Baxter, Glyn Lewis, Peter B Jones, Golam M Khandaker

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Mentions

48
Peak: 14 in Jul 2019
across 5 sources since Jul 2019

Extended reach

293,622
potential audience

Total likes

62

Video views

1,625

Mentions per month

Jul 2019 – Dec 2025

Where it's discussed

  • X / Twitter37 posts
  • News5 articles
  • YouTube4 videos
  • Facebook1 posts
  • TikTok1 posts

AI synopsis

What people are saying

The discussions reflect a positive and analytical attitude, with many posts citing specific statistics such as 'a quarter of patients' with depression having low-grade inflammation, and referencing the meta-analytical approach, which shows their active engagement and recognition of the study’s potential to impact future research and treatment approaches.

AgreementModerate agreement

Most discussions acknowledge the findings, with many emphasizing that a significant portion of depressed patients show signs of low-grade inflammation, indicating general support for the publication's conclusions.

InterestHigh interest

The discussions demonstrate high curiosity, highlighted by phrases like 'A quarter of patients' and references to precise statistical data, showing engagement with the research.

EngagementModerate engagement

Posts contain references to the methodology and statistical details, such as mentions of 'meta-analysis' and 'heterogeneity,' indicating active analysis and deep engagement.

ImpactModerate impact

Bloggers and commentators recognize the importance of these findings, noting it could influence future treatments and understanding of depression, highlighting the potential significance of the research.

Abstract in brief

  • The systematic review and meta-analysis found that about 27% of people with depression have low-grade inflammation, indicated by CRP levels of 3 mg/L or higher, and this rate is consistent across different groups.
  • More than half of depressed patients (around 58%) show mildly elevated CRP levels (above 1 mg/L), and the odds of having inflammation are significantly higher in depressed individuals compared to healthy controls.
  • These results suggest that inflammation might be an important factor for a substantial portion of people with depression, potentially serving as a target for future treatments.]

Top posts

Most liked on X and Bluesky
Jesus Ramirez-Bermudez
@JRBneuropsiq · X

Source: Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels https://t.co/6Cx2VCSLPF

Feb 4, 2023 · 11 likes · 1 share · 31,449 followers View post →
Golam Khandaker
@golam_khandaker · X

A quarter of patients with depression show evidence of low-grade inflammation. Patients are about 50% more likely to have evidence of inflammation than controls. See our meta-analysis published in @PsychMedJournal - https://t.co/9KIWs7dZfc Well done @eosimo

Jul 3, 2019 · 9 likes · 6 shares · 2,185 followers View post →
Saúl Sánchez
@SaulNutri · X

May 7, 2023 · 8 likes · 1 share · 108,151 followers View post →
Christoph Burch
@ChristophBurch · X

Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels Osimo et al. Psychol Med. 2019 #openaccess https://t.co/TmfvwaUB4K https://t.co/FU9SbASYqX

Aug 28, 2019 · 8 likes · 4 shares · 15,641 followers View post →
Pedro Carrera Bastos
@pmcbastos · X

@CuiProdest_ Efectivamente: https://t.co/RPKAeH1tMS

Feb 9, 2020 · 6 likes · 2 shares · 1,469 followers View post →
Dr Chris Norris
@drchrisnorris · X

Low grade inflammation (LGI) and depression - open access https://t.co/zRyuIKBBeE https://t.co/f6hYK91634

Oct 31, 2021 · 2 likes · 1 share · 1,708 followers View post →

All mentions

Fredy
@AlfredoRuizRod7 · X

RT @SaulNutri:

May 7, 2023 · 1 share · 7 followers View post →
Saúl Sánchez
@SaulNutri · X

May 7, 2023 · 8 likes · 1 share · 108,151 followers View post →
Thierry zucco
@ZuccoT · X

RT @BlancFrdric7: https://t.co/bsQxBObit3

Mar 1, 2023 · 2 shares · 572 followers View post →
Philippe de Linares ⚓
@LinaresPhilippe · X

RT @BlancFrdric7: https://t.co/bsQxBObit3

Mar 1, 2023 · 2 shares · 246 followers View post →
Frédéric Blanc
@BlancFrdric7 · X

https://t.co/bsQxBObit3 https://t.co/y9pvsyk6AK

Feb 27, 2023 · 2 likes · 2 shares · 943 followers View post →
Marcia S Newman
@marciasgreen · X

Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels https://t.co/MT0lyiW2mr

Feb 6, 2023 · 4,951 followers View post →
Marcia S Newman
@marciasgreen · X

RT @JRBneuropsiq: Source: Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels https:/…

Feb 6, 2023 · 1 share · 4,951 followers View post →
Jesus Ramirez-Bermudez
@JRBneuropsiq · X

Source: Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels https://t.co/6Cx2VCSLPF

Feb 4, 2023 · 11 likes · 1 share · 31,449 followers View post →
PF Anderson @pfanderson@disabled.social
@pfanderson · X

Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels - PubMed https://t.co/WVEXN2bvhP

Oct 26, 2022 · 10,755 followers View post →
Madhan Ramanathan
@sportsphysiouk · X

RT @drchrisnorris: Low grade inflammation (LGI) and depression - open access https://t.co/zRyuIKBBeE https://t.co/f6hYK91634

Oct 31, 2021 · 1 share · 1,130 followers View post →
Dr Chris Norris
@drchrisnorris · X

Low grade inflammation (LGI) and depression - open access https://t.co/zRyuIKBBeE https://t.co/f6hYK91634

Oct 31, 2021 · 2 likes · 1 share · 1,708 followers View post →
Dr.やまて@海外の最新健康情報/親子向け情報/NEWSシェア
@yamatedentist · X

37件(被験者13541人)の研究を分析した結果、「鬱病でCRPが有意に上昇する」と結論付けた。CRPとは体内で炎症が起こると増えるタンパク質のこと。 つまり鬱は「心の炎症」ともいいえなくもない。 https://t.co/8Nx1p9P2xM https://t.co/PYG9PkRKHJ

Sep 1, 2020 · 1 like · 24 followers View post →
IberianCitizen
@IberianCitizen · X

RT @pmcbastos: @CuiProdest_ Efectivamente: https://t.co/RPKAeH1tMS

Feb 10, 2020 · 2 shares · 12,901 followers View post →
javierbutra
@javierbutra · X

RT @pmcbastos: @CuiProdest_ Efectivamente: https://t.co/RPKAeH1tMS

Feb 10, 2020 · 2 shares · 14,352 followers View post →
Pedro Carrera Bastos
@pmcbastos · X

@CuiProdest_ Efectivamente: https://t.co/RPKAeH1tMS

Feb 9, 2020 · 6 likes · 2 shares · 1,469 followers View post →
Severi Luoto
@SeveriLuoto · X

@WiringTheBrain And a recent review article: https://t.co/qAqzanpfgE https://t.co/y9HO3aBt0L

Jan 20, 2020 · 1,118 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @TrendsPsych: Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels #depression #ment…

Sep 13, 2019 · 1 share · 6,690 followers View post →
Trends in Psychiatry
@TrendsPsych · X

Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels #depression #mentalhealth https://t.co/QQzODQUxYf

Sep 13, 2019 · 1 share · 553 followers View post →
SidebySide for #MentalHealth
@ByYrSide · X

RT @golam_khandaker: A quarter of patients with depression show evidence of low-grade inflammation. Patients are about 50% more likely to h…

Sep 5, 2019 · 6 shares · 2,356 followers View post →
EskeleThor
@EskeleThor · X

RT @ChristophBurch: Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels Osimo et al. P…

Aug 29, 2019 · 4 shares · 403 followers View post →
Pan Intzirtzis
@IntziP · X

RT @ChristophBurch: Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels Osimo et al. P…

Aug 28, 2019 · 4 shares · 146 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @ChristophBurch: Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels Osimo et al. P…

Aug 28, 2019 · 4 shares · 6,690 followers View post →
Christoph Burch
@ChristophBurch · X

Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels Osimo et al. Psychol Med. 2019 #openaccess https://t.co/TmfvwaUB4K https://t.co/FU9SbASYqX

Aug 28, 2019 · 8 likes · 4 shares · 15,641 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @MazenSalama: Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels - https://t.co/T6c…

Jul 9, 2019 · 1 share · 6,690 followers View post →
Dataemia
@Dataemia · X

Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels - https://t.co/T6cfITCrzr

Jul 9, 2019 · 1 share · 959 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @ucl_discovery: Open Access UCL Research: Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of…

Jul 9, 2019 · 1 share · 6,690 followers View post →
UCL Discovery
@ucl_discovery · X

Open Access UCL Research: Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels https://t.co/WbbtnS2Z0o

Jul 9, 2019 · 1 share · 2,507 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @raj_psyc: A quarter of patients with #depression show evidence of low-grade #inflammation (OR-1.46), Over 50% show mildly elevated #CR…

Jul 8, 2019 · 3 shares · 6,690 followers View post →
Agnes Ayton
@AgnesAyton · X

RT @raj_psyc: A quarter of patients with #depression show evidence of low-grade #inflammation (OR-1.46), Over 50% show mildly elevated #CR…

Jul 8, 2019 · 3 shares · 7,429 followers View post →
Co•Production Norfolk
@CoProNorfolk · X

RT @raj_psyc: A quarter of patients with #depression show evidence of low-grade #inflammation (OR-1.46), Over 50% show mildly elevated #CR…

Jul 8, 2019 · 3 shares · 4,627 followers View post →
raj_psyc
@raj_psyc · X

A quarter of patients with #depression show evidence of low-grade #inflammation (OR-1.46), Over 50% show mildly elevated #CRP levels (OR=1.47) SR/MA (37 studies with 13,541 patients with 155,728 controls) Note #Heterogeneity https://t.co/d3gRd9Jhsl

Jul 8, 2019 · 1 like · 3 shares · 12,577 followers View post →
Prof Helen L. Fisher
@HelenLFisher · X

RT @golam_khandaker: A quarter of patients with depression show evidence of low-grade inflammation. Patients are about 50% more likely to h…

Jul 4, 2019 · 6 shares · 3,683 followers View post →
Research at CPFT
@CPFT_Research · X

RT @golam_khandaker: A quarter of patients with depression show evidence of low-grade inflammation. Patients are about 50% more likely to h…

Jul 4, 2019 · 6 shares · 2,912 followers View post →
Jas
@ptork66 · X

RT @golam_khandaker: A quarter of patients with depression show evidence of low-grade inflammation. Patients are about 50% more likely to h…

Jul 4, 2019 · 6 shares · 82 followers View post →
Emanuele Osimo
@eosimo · X

RT @golam_khandaker: A quarter of patients with depression show evidence of low-grade inflammation. Patients are about 50% more likely to h…

Jul 3, 2019 · 6 shares · 813 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @golam_khandaker: A quarter of patients with depression show evidence of low-grade inflammation. Patients are about 50% more likely to h…

Jul 3, 2019 · 6 shares · 6,690 followers View post →
Golam Khandaker
@golam_khandaker · X

A quarter of patients with depression show evidence of low-grade inflammation. Patients are about 50% more likely to have evidence of inflammation than controls. See our meta-analysis published in @PsychMedJournal - https://t.co/9KIWs7dZfc Well done @eosimo

Jul 3, 2019 · 9 likes · 6 shares · 2,185 followers View post →
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