January 2020 PMID 31283837

Linoleic acid-derived metabolites constitute the majority of oxylipins in the rat pup brain and stimulate axonal growth in primary rat cortical neuron-glia co-cultures in a sex-dependent manner.

Marie Hennebelle, Rhianna K Morgan, Sunjay Sethi, Zhichao Zhang, Hao Chen, Ana Cristina Grodzki, Pamela J Lein, Ameer Y Taha

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Mentions

Peak: 2 in Mar 2022

across 2 sources since Jul 2019

Extended reach

11,357

potential audience

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Video views

1,113

Mentions per month

Jul 2019 – Jan 2025

Where it's discussed

X / Twitter3 posts
YouTube2 videos

AI synopsis

What people are saying

The discussions reflect a generally positive attitude, emphasizing the use of innovative techniques and the implications for brain development, such as the statement praising the resource from mgi_mouse and mentions of sex-dependent neuronal effects, which underscores their perceived significance. The tone varies from technical acknowledgment to mild enthusiasm, contributing to an overall impression of interest with an understanding of the potential impact.

AgreementModerate agreement

Most discussions acknowledge the significance of the findings, especially highlighting the sex-dependent effects on neuronal growth.

InterestModerate interest

Participants demonstrate moderate curiosity, as seen in references to methods and potential applications, but depth of focus varies.

EngagementModerate engagement

While some posts show active engagement by mentioning the resource used and the importance of open science, others are more superficial.

ImpactModerate impact

The mention of methodology and biological insights suggests a recognition of the study's potential influence on neuroscience research.

Abstract in brief

The study found that linoleic acid (LA) and its oxidized metabolites (OXLAMs) are major components in the brains of 1-day-old rat pups, with levels and roles that may differ between sexes.
Both LA and 13HODE, a key OXLAM, promote axonal growth in primary rat cortical neurons, but their effects depend on the sex of the pups, with LA boosting growth in females and 13HODE in males.
Overall, the research highlights that these fatty acids and their metabolites are involved in early brain development and exhibit sex-specific influences on neuronal growth.]

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All mentions

Understanding Sunflower Oil: Oxidized Metabolites and Health Impacts

This video explores whether sunflower oil is healthy by analyzing oxidized metabolites OXLAMS and 9HODE, which are linked to inflammation and disease. It discusses how a balanced diet affects these substances and offers…

Vital Aging World · Dec 30, 2024 828 views

Understanding OXLAMS and 9HODE in Inflammation Processes

This episode explores oxidized metabolites of Omega6 fatty acid Linoleic acid, OXLAMS and 9HODE, their formation, and role in inflammation and diseases. Learn about the balance between Omega3 and Omega6 for health.

Vital Aging Lab · Jan 28, 2025 285 views

OpenSci Talk

@OpenSciTalk · X

RT @RobotRrid: .@mgi_mouse your resource, https://t.co/E6dUZ9xP4I, was just reported to be used in "Linoleic acid-derived metabolites const…

Mar 20, 2022 · 1 share · 4,088 followers View post →

RRID Robot

@RobotRrid · X

.@mgi_mouse your resource, https://t.co/E6dUZ9xP4I, was just reported to be used in "Linoleic acid-derived metabolites constitute the m…": https://t.co/bNCHlJDN4h (https://t.co/1892IpRAe6). Thank you for making your #methodsmatter. #OpenScience

Mar 20, 2022 · 1 share · 161 followers View post →

BioMassSpec

@realBioMassSpec · X

Jul 10, 2019 · 5,991 followers View post →