Ann Intern Med August 2019 PMID 31284301

Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia: A Multihospital Cohort Study.

Valerie M Vaughn, Scott A Flanders, Ashley Snyder, Anna Conlon, Mary A M Rogers, Anurag N Malani, Elizabeth McLaughlin, Sarah Bloemers, Arjun Srinivasan, Jerod Nagel, Scott Kaatz, Danielle Osterholzer, Rama Thyagarajan, Lama Hsaiky, Vineet Chopra

Full text PDF Download social card

Mentions

130

Peak: 58 in Jul 2019

across 5 sources since Jul 2019

Extended reach

380,678

potential audience

Total likes

102

Video views

Mentions per month

Jul 2019 – Aug 2025

Where it's discussed

X / Twitter83 posts
News32 articles
Facebook8 posts
Blogs6 articles
YouTube1 videos

AI synopsis

What people are saying

Many discussions highlight key findings of the research, particularly the point that two-thirds of patients received excessive antibiotics, leading to increased adverse events. Phrases like 'important and overlooked detail' and 'keep duration short' reflect a sense of urgency and seriousness in addressing antibiotic overuse. The tone in these discussions conveys a proactive approach to changing clinical guidelines based on the study's outcomes.

AgreementStrong agreement

The majority of discussions express strong support for the findings regarding excessive antibiotic use.

InterestHigh interest

Participants show a high level of curiosity about the implications of antibiotic duration on patient outcomes.

EngagementModerate engagement

While many posts reference the study, few delve deeply into the specifics of the methodology or data.

ImpactHigh impact

Users perceive the study's contributions to antibiotic stewardship as having a considerable influence on clinical practices.

Abstract in brief

The study examined the impact of excessive antibiotic treatment duration on patients hospitalized with pneumonia across 43 hospitals in Michigan.
Approximately two-thirds of the 6,481 patients received more antibiotics than necessary, particularly at discharge, with factors like respiratory cultures and previous antibiotic use influencing this excess.
Despite the overuse of antibiotics, the study found no reduction in adverse outcomes such as readmissions or infections, but each extra day of treatment increased the risk of antibiotic-related side effects by 5%.

Read the full abstract

All mentions

Optimal Duration of Antibiotic Therapy in Complex Infections

In this episode, we address a clinical question faced daily: Is it possible to end antibiotic treatment? The optimal duration of treatment is crucial yet complex, as findings show that every extra day of antibiotics…

SEIMC · Aug 12, 2025 8 views

Galadriel Pellejero

@ListeriaC · X

2/ ¿Cómo medimos la duración del tratamiento al alta hospitalaria?

Feb 15, 2025 · 150 followers View post →

Valerie Vaughn

@ValerieVaughnMD · X

RT @IDPharmacist: @accpinfdprn This work by @ValerieVaughnMD has also been helpful in discussions with our hospitalists re: #DurationofTx f…

May 6, 2021 · 1 share · 1,949 followers View post →

Melissa Johnson

@IDPharmacist · X

@accpinfdprn This work by @ValerieVaughnMD has also been helpful in discussions with our hospitalists re: #DurationofTx for pneumonia #IDPrn https://t.co/HNnrbQ2ORu

May 6, 2021 · 4 likes · 1 share · 4,144 followers View post →

Dusten Rose

@stellarelement · X

@RebekkaAnn Such an important and overlooked detail! It’s easy to be compliant with shorter courses or no antibiotics at discharge! #math #saveantibiotics

Sep 2, 2020 · 2 likes · 404 followers View post →

พิม.

@pimuaitsu · X

RT @2minmed: #VisualAbstract: Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia https://t.co/…

Oct 12, 2019 · 12 shares · 296 followers View post →

Francesca Gioia

@FrancescaGioi10 · X

RT @2minmed: #VisualAbstract: Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia https://t.co/…

Oct 11, 2019 · 12 shares · 236 followers View post →

ana maria

@anitamehlis · X

https://t.co/qKrRcLp3Hq

Oct 9, 2019 · 53 followers View post →

MD.Tafyan

@MD_Tafyan · X

RT @2minmed: #VisualAbstract: Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia https://t.co/…

Oct 8, 2019 · 12 shares · 421 followers View post →

Tejal Gandhi

@Tejal_N_Gandhi · X

RT @2minmed: #VisualAbstract: Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia https://t.co/…

Oct 8, 2019 · 12 shares · 284 followers View post →

2 Minute Medicine®

@2minmed · X

RT @2minmed: #VisualAbstract: Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia https://t.co/…

Oct 8, 2019 · 12 shares · 5,405 followers View post →

Megan Rose Carr LaPorte

@mlaporteMD · X

RT @2minmed: #VisualAbstract: Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia https://t.co/…

Oct 8, 2019 · 12 shares · 193 followers View post →

Sang Usayaporn

@ABOsteward · X

RT @2minmed: #VisualAbstract: Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia https://t.co/…

Oct 8, 2019 · 12 shares · 152 followers View post →

Sidnei Santos

@sidneiocds · X

RT @2minmed: #VisualAbstract: Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia https://t.co/…

Oct 7, 2019 · 12 shares · 173 followers View post →

Kamol

@KamolMU · X

RT @2minmed: #VisualAbstract: Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia https://t.co/…

Oct 7, 2019 · 12 shares · 101 followers View post →

Valerie Vaughn

@ValerieVaughnMD · X

RT @2minmed: #VisualAbstract: Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia https://t.co/…

Oct 7, 2019 · 12 shares · 1,949 followers View post →

2 Minute Medicine®

@2minmed · X

#VisualAbstract: Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia https://t.co/UMSg0yoeLc #StudyGraphics #adverseevent https://t.co/7YQHWx4Wn1

Oct 7, 2019 · 15 likes · 12 shares · 5,405 followers View post →

Bhuvan K.C.

@kcnomics · X

RT @LessIsMoreMed: Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia: A Multihospital Cohort…

Sep 27, 2019 · 1 share · 242 followers View post →

Dr Jessica Otte, CCFP, FCFP

@LessIsMoreMed · X

Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia: A Multihospital Cohort Study. - PubMed - NCBI https://t.co/ZJH2krmgpw via @pearltrees

Sep 27, 2019 · 1 like · 1 share · 6,060 followers View post →

David Llantén

@d_llanten · X

RT @AnnalsofIM: Check out these clinical practice points on excess #antibiotic treatment duration and adverse events in patients hospitaliz…

Aug 9, 2019 · 4 shares · 386 followers View post →

Antibiotic Steward Bassam Ghanem

@ABsteward · X

RT @AnnalsofIM: Check out these clinical practice points on excess #antibiotic treatment duration and adverse events in patients hospitaliz…

Aug 9, 2019 · 4 shares · 59,550 followers View post →

GhostWarrior⚔

@ghostcatbce · X

RT @AnnalsofIM: Check out these clinical practice points on excess #antibiotic treatment duration and adverse events in patients hospitaliz…

Aug 9, 2019 · 4 shares · 2,475 followers View post →

Save Antibiotics

@saveantibiotics · X

RT @AnnalsofIM: Check out these clinical practice points on excess #antibiotic treatment duration and adverse events in patients hospitaliz…

Aug 9, 2019 · 4 shares · 15,321 followers View post →

Annals of Int Med

@AnnalsofIM · X

Check out these clinical practice points on excess #antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia https://t.co/6iWreWJ2EI. #MedEd https://t.co/ylfUrcifXc

Aug 9, 2019 · 2 likes · 4 shares · 72,419 followers View post →

HCP Feed

@FeedHcp · X

Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia A Multihospital Cohort Study,,https://t.co/Rm4sBcYm6y,

Aug 5, 2019 · 24 followers View post →

Patient Safety Enhancement Program (UMVA)

@PSEPUMVA · X

*scans list* "Cool stuff!" *record scratch* *double take* "Hey! I know that paper title!" *looks closer*

Aug 5, 2019 · 950 followers View post →

Aisling Rafferty

@AisRafferty · X

RT @robcunney: 5%⬆️ adverse events for each day excess #antibiotic for CAP: keep duration short! https://t.co/5tTODpjtf0 @AMSInSight @DrNua…

Jul 27, 2019 · 10 shares · 80 followers View post →

SDSF

@isatirl · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 22, 2019 · 14 shares · 658 followers View post →

Ebymar Arismendi

@EbymarArismendi · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 22, 2019 · 14 shares · 126 followers View post →

SergioAquino

@SergioAquinoOk · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 21, 2019 · 14 shares · 1,028 followers View post →

Carolina.Uribe

@Carolina_UribeR · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 21, 2019 · 14 shares · 129 followers View post →

Mauro Gomes

@dr_maurogomes · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 21, 2019 · 14 shares · 461 followers View post →

Leticia Martínez Campos

@LetiMarCam · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 21, 2019 · 14 shares · 1,615 followers View post →

Carlos Dueñas

@CarlosJ_Duenas · X

RT @juanelosag: "Two thirds of patients (hospitalized with pneumonia) received excess antibiotic therapy...Excess antibiotic treatment was…

Jul 21, 2019 · 1 share · 455 followers View post →

Laura Valdesoiro

@LauraValdesoiro · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 21, 2019 · 14 shares · 209 followers View post →

Almansour

@malmansour81 · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 21, 2019 · 14 shares · 209 followers View post →

osenvira

@osenvira · X

RT @IlindelatorreMD: Esto debe ser un llamado para que los médicos receten y documenten al momento del alta de la terapia con antibióticos…

Jul 21, 2019 · 9 shares · 1,360 followers View post →

Pediatric Pulmonology - Luigi Cutolo, MD, PhD

@lucutolo · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 21, 2019 · 14 shares · 570 followers View post →

Yurisita

@yurisita411 · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 20, 2019 · 14 shares · 694 followers View post →

Lydiana Avila

@LydianaAvila · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 20, 2019 · 14 shares · 427 followers View post →

Kada Bentata

@bentatakadaalg · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 20, 2019 · 14 shares · 394 followers View post →

SENP

@SENPneumoped · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 20, 2019 · 14 shares · 2,068 followers View post →

AvancesMedicos

@MedicosAvances · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 20, 2019 · 14 shares · 176 followers View post →

American Thoracic Society (ATS)

@atscommunity · X

Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort study: https://t.co/HUd8Bioujs

Jul 20, 2019 · 25 likes · 14 shares · 41,967 followers View post →

Dr Suja Somanadhan

@sujas15 · X

RT @robcunney: 5%⬆️ adverse events for each day excess #antibiotic for CAP: keep duration short! https://t.co/5tTODpjtf0 @AMSInSight @DrNua…

Jul 20, 2019 · 10 shares · 3,423 followers View post →

Héctor Carvajal

@DrHCarvajal · X

RT @IlindelatorreMD: Esto debe ser un llamado para que los médicos receten y documenten al momento del alta de la terapia con antibióticos…

Jul 20, 2019 · 9 shares · 1,692 followers View post →

Mª Dolores Díaz

@mdialop1 · X

RT @jbb4jbb4: Excess Antibiotic Use in Patients Hospitalized With Pneumonia | Ann Intern Med | ACP | https://t.co/ytoHT3wYRs

Jul 20, 2019 · 1 share · 114 followers View post →

Adaucio Morales

@adaucior · X

RT @IlindelatorreMD: Esto debe ser un llamado para que los médicos receten y documenten al momento del alta de la terapia con antibióticos…

Jul 20, 2019 · 9 shares · 113 followers View post →

JuanManuel

@JuanmaTorrado · X

RT @IlindelatorreMD: Esto debe ser un llamado para que los médicos receten y documenten al momento del alta de la terapia con antibióticos…

Jul 19, 2019 · 9 shares · 569 followers View post →

Pseudo-mona

@LissMinelli · X

RT @IlindelatorreMD: Esto debe ser un llamado para que los médicos receten y documenten al momento del alta de la terapia con antibióticos…

Jul 19, 2019 · 9 shares · 313 followers View post →

Agelvis Martínez MD

@agelvisr · X

RT @IlindelatorreMD: Esto debe ser un llamado para que los médicos receten y documenten al momento del alta de la terapia con antibióticos…

Jul 19, 2019 · 9 shares · 280 followers View post →

Dr. Ilin Gilberto de la Torre M.

@IlindelatorreMD · X

Jul 19, 2019 · 20 likes · 9 shares · 45,837 followers View post →

Ciara Kirke

@ciarakirke · X

RT @robcunney: 5%⬆️ adverse events for each day excess #antibiotic for CAP: keep duration short! https://t.co/5tTODpjtf0 @AMSInSight @DrNua…

Jul 19, 2019 · 10 shares · 2,832 followers View post →

TSCUH Research

@TSCUHresearch · X

RT @robcunney: 5%⬆️ adverse events for each day excess #antibiotic for CAP: keep duration short! https://t.co/5tTODpjtf0 @AMSInSight @DrNua…

Jul 19, 2019 · 10 shares · 830 followers View post →

Karen Burns

@dfeatamr · X

RT @robcunney: 5%⬆️ adverse events for each day excess #antibiotic for CAP: keep duration short! https://t.co/5tTODpjtf0 @AMSInSight @DrNua…

Jul 19, 2019 · 10 shares · 634 followers View post →

Clare Rock MD MS

@ClareRock1 · X

RT @robcunney: 5%⬆️ adverse events for each day excess #antibiotic for CAP: keep duration short! https://t.co/5tTODpjtf0 @AMSInSight @DrNua…

Jul 19, 2019 · 10 shares · 832 followers View post →

Rob Cunney

@robcunney · X

5%⬆️ adverse events for each day excess #antibiotic for CAP: keep duration short! https://t.co/5tTODpjtf0 @AMSInSight @DrNuala @astghughes @EasyASP @dfeatamr @FfitzP @ClareRock1 @raseaton66

Jul 19, 2019 · 15 likes · 10 shares · 1,778 followers View post →

Juan Berenguer

@jbb4jbb4 · X

Excess Antibiotic Use in Patients Hospitalized With Pneumonia | Ann Intern Med | ACP | https://t.co/ytoHT3wYRs

Jul 19, 2019 · 1 like · 1 share · 576 followers View post →

Juan E Losa. Infectólogo. HUFA. URJC. Sandoval Sur

@juanelosag · X

"Two thirds of patients (hospitalized with pneumonia) received excess antibiotic therapy...Excess antibiotic treatment was associated with patient-reported adverse events". Vaugh VM, et al. Ann Intern Med 2019; doi: 10.7326/M18-3640. https://t.co/k3z5VXl9VW

Jul 16, 2019 · 3 likes · 1 share · 3,815 followers View post →

MRPM

@surfactante · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 13, 2019 · 9 shares · 275 followers View post →

Enrique Zamora García

@EzamoraGarc · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 13, 2019 · 9 shares · 2,656 followers View post →

Rev.Pat.Respiratoria

@PatRespiratoria · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 13, 2019 · 9 shares · 4,298 followers View post →

Pediatric Pulmonology - Luigi Cutolo, MD, PhD

@lucutolo · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 12, 2019 · 9 shares · 570 followers View post →

Equity and Health

@equityhealthdev · X

RT @GlobalPHObserv: Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With #Pneumonia: A Multihospital Cohor…

Jul 12, 2019 · 2 shares · 3,465 followers View post →

Culture of Health Eq

@CofHEQ · X

RT @GlobalPHObserv: Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With #Pneumonia: A Multihospital Cohor…

Jul 12, 2019 · 2 shares · 1,094 followers View post →

Jubert Benedicto

@pulmodocjubert · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 12, 2019 · 9 shares · 857 followers View post →

Patrick A. Laird, DNP, APRN, ACNP-BC, NEA-BC

@Patrick_A_Laird · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 12, 2019 · 9 shares · 122 followers View post →

Andrea Levine

@LetMeIntubateU · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 12, 2019 · 9 shares · 412 followers View post →

diego acosta

@diegofacostah · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 12, 2019 · 9 shares · 25 followers View post →

Oscar Gabriel Jiménez

@OscarGJC · X

RT @atscommunity: Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort…

Jul 12, 2019 · 9 shares · 630 followers View post →

American Thoracic Society (ATS)

@atscommunity · X

Excess antibiotic treatment duration and adverse events in patients hospitalized with #pneumonia: A multihospital cohort study: https://t.co/HUd8BiG5b0

Jul 12, 2019 · 8 likes · 9 shares · 41,967 followers View post →

Global Health Observ

@GlobalPHObserv · X

Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With #Pneumonia: A Multihospital Cohort Study https://t.co/3CnDfCbYpn

Jul 11, 2019 · 2 likes · 2 shares · 6,541 followers View post →

Maria Queralt Gorgas

@qgorgas · X

RT @petita_libelula: Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia: A Multihospital Cohor…

Jul 10, 2019 · 1 share · 1,465 followers View post →

Bob Jordan

@BobJordanHLC · X

RT @TodaysHospital: Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia https://t.co/jncBGYvnkN

Jul 9, 2019 · 1 share · 201 followers View post →

IndianaACP

@AcpIndiana · X

Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia https://t.co/pEliPyo2GI

Jul 9, 2019 · 316 followers View post →

ArkansasACP

@ArkansasACP · X

Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia https://t.co/yWzOZnmGyL

Jul 9, 2019 · 292 followers View post →

IllinoisACP

@IllinoisACP · X

Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia https://t.co/9MpS6GYf1b

Jul 9, 2019 · 639 followers View post →

Today's Hospitalist

@TodaysHospital · X

Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia https://t.co/jncBGYvnkN

Jul 9, 2019 · 1 like · 1 share · 2,952 followers View post →

SMARTMD

@SMART_MD · X

Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia: A Multihospital Cohort Study https://t.co/9jnsu3ZAgJ via @AnnalsofIM

Jul 9, 2019 · 3,871 followers View post →

Sara Ortonobes

@petita_libelula · X

Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia: A Multihospital Cohort Study https://t.co/rhnthrn0Bm

Jul 9, 2019 · 1 like · 1 share · 388 followers View post →

Elizabeth Monsees

@eamonsees · X

RT @UM_IHPI: NEW: @ValerieVaughnMD & colleagues report their findings about overprescribing of #antibiotics to #pneumonia patients in a new…

Jul 8, 2019 · 3 shares · 146 followers View post →

Valerie Vaughn

@ValerieVaughnMD · X

RT @UM_IHPI: NEW: @ValerieVaughnMD & colleagues report their findings about overprescribing of #antibiotics to #pneumonia patients in a new…

Jul 8, 2019 · 3 shares · 1,949 followers View post →

Pub Health Monitor

@monitor_PH · X

RT @UM_IHPI: NEW: @ValerieVaughnMD & colleagues report their findings about overprescribing of #antibiotics to #pneumonia patients in a new…

Jul 8, 2019 · 3 shares · 1,825 followers View post →

U-M IHPI

@UM_IHPI · X

NEW: @ValerieVaughnMD & colleagues report their findings about overprescribing of #antibiotics to #pneumonia patients in a new @AnnalsofIM paper: https://t.co/GR6DtImcyB https://t.co/vQEXgxeKQR

Jul 8, 2019 · 2 likes · 3 shares · 7,479 followers View post →

Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia: A Multihospital Cohort Study.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Optimal Duration of Antibiotic Therapy in Complex Infections