PubHawk
Int J Mol Sci August 2019 PMID 31374866

Propolis Reduces the Expression of Autophagy-Related Proteins in Chondrocytes under Interleukin-1β Stimulus.

Consuelo Arias, Nicolás Saavedra, Kathleen Saavedra, Marysol Alvear, Alejandro Cuevas, Silvya Stuchi Maria-Engler, Dulcineia S P Abdalla, Luis A Salazar

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Mentions

3
Peak: 1 in Aug 2019
across 2 sources since Aug 2019

Extended reach

1,827
potential audience

Total likes

9

Video views

83

Mentions per month

Aug 2019 – Aug 2024

Where it's discussed

  • X / Twitter2 posts
  • YouTube1 videos

AI synopsis

What people are saying

The discussions highlight the potential of propolis to regulate cartilage health by mentioning its effects on autophagy-related proteins and osteoarthritis markers, using words like 'promising' and 'potential' that convey cautious optimism and a moderate level of engagement with the research's implications.

AgreementModerate agreement

Most discussions express some level of support or positive recognition of the research findings, indicating general agreement with its potential significance.

InterestModerate interest

Participants show moderate curiosity, as they acknowledge the study's relevance to osteoarthritis but do not delve deeply into detailed mechanisms.

EngagementModerate engagement

The discussions reflect some engagement with the content, with mentions of molecular pathways and potential therapeutic effects, though not extensively explored.

ImpactModerate impact

There is a perception that the findings could have meaningful implications for osteoarthritis treatment, though the overall tone remains cautious.

Abstract in brief

  • Propolis extract (EEP) decreases the expression of autophagy-related proteins (LC3, ATG5, AKT1) in chondrocytes stimulated with IL1, which suggests it may help regulate the autophagy pathway involved in osteoarthritis.
  • EEP treatment reduces nitric oxide production, lowers osteoarthritis markers like MMP13, and increases markers of healthy cartilage such as collagen II, indicating potential protective effects on damaged cartilage.
  • The study suggests that EEP could have beneficial effects for osteoarthritis by modulating molecular pathways in chondrocytes, potentially decreasing cartilage breakdown and promoting cartilage health.]
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Top posts

Most liked on X and Bluesky
Autophagy Papers
@AutophagyPapers · X

Propolis Reduces the Expression of Autophagy-Related Proteins in Chondrocytes under Interleukin-1β Stimulus. https://t.co/WNrfqb59PH

Aug 4, 2019 · 1,705 followers View post →
Health Time
@healthtimetaylo · X

Propolis reduces the expression of autophagy-related proteins in chondrocytes under interleukin-1β stimulus. https://t.co/YhZoHorhrr

Dec 10, 2019 · 40 followers View post →

All mentions

Health Time
@healthtimetaylo · X

Propolis reduces the expression of autophagy-related proteins in chondrocytes under interleukin-1β stimulus. https://t.co/YhZoHorhrr

Dec 10, 2019 · 40 followers View post →
Autophagy Papers
@AutophagyPapers · X

Propolis Reduces the Expression of Autophagy-Related Proteins in Chondrocytes under Interleukin-1β Stimulus. https://t.co/WNrfqb59PH

Aug 4, 2019 · 1,705 followers View post →