J Affect Disord November 2019 PMID 31382100

Classical psychedelics for the treatment of depression and anxiety: A systematic review.

Silvia Muttoni, Maddalena Ardissino, Christopher John

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Mentions

78
Peak: 28 in Aug 2019
across 6 sources since Aug 2019

Extended reach

135,181
potential audience

Total likes

511

Video views

10,877

Mentions per month

Aug 2019 – Dec 2021

Where it's discussed

  • X / Twitter43 posts
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AI synopsis

What people are saying

Discussions reveal a positive overall sentiment towards the publication, with many emphasizing its promising results and potential to change mental health treatments. For example, phrases like 'incredible results' and 'sustained beneficial effects' highlight the excitement about the findings, while comments on system barriers—such as 'the problem is the prohibition'—underscore the belief in its societal significance.

AgreementModerate agreement

Most discussions reflect support for the research, highlighting positive findings about psychedelics' potential in treating depression and anxiety, with words like 'incredible results' and 'beneficial effects' indicating strong agreement.

InterestHigh interest

Posts demonstrate high curiosity, referencing diverse studies, the history of research, and societal implications, which shows active engagement with the topic.

EngagementModerate engagement

Several discussions involve referencing specific outcomes, such as sustained antidepressant effects and minimal side effects, suggesting a deeper exploration of the research findings.

ImpactHigh impact

The tone suggests that respondents perceive this research as significant, with statements about the treatment's transformative potential and a desire for greater understanding and acceptance, implying high perceived impact.

Abstract in brief

  • This systematic review examines the potential of classical psychedelics like ayahuasca, psilocybin, and LSD as alternative treatments for depression and anxiety, especially in cases resistant to traditional therapies.
  • The analysis of seven clinical trials involving 130 patients shows that psychedelics can produce immediate and sustained improvements in depression and anxiety symptoms, with minimal and transient side effects such as headaches, nausea, and mild cardiovascular changes.
  • Due to the limited number of studies and participants, more research is needed, but current evidence suggests that psychedelics could be a promising and well-tolerated option for managing treatment-resistant depression and anxiety.

Top posts

Most liked on X and Bluesky
Arnþór
@arnthorjon · X

#Psychedelic treatments produced significant and sustained #antidepressant and #anxiolytic effects, were well tolerated and with no persisting adverse effects. Classical psychedelics for the treatment of #depression and #anxiety: A systematic review https://t.co/k7GR4SiGrj

Aug 5, 2019 · 11 likes · 10 shares · 1,397 followers View post →
Amsterdam Psychedelic Research Association (APRA)
@APRAresearch · X

Classical psychedelics for the treatment of depression and anxiety: A systematic review. https://t.co/DbBWryQ8Ze

Aug 6, 2019 · 2 likes · 4 shares · 4,008 followers View post →
Amsterdam Psychedelic Research Association (APRA)
@APRAresearch · X

Classical psychedelics for the treatment of depression and anxiety: A systematic review. https://t.co/9JrsdfnMHW

Jul 14, 2020 · 2 likes · 4,008 followers View post →
Arrigo Piantavanci
@pat7331 · X

@Alessan67153720 @RijkM73 @Blowjoint @GianpaoL0 @klaudioz83 @AzzurraBarbuto @Mov5Stelle Vede qual è il problema, la chiusura preclude la conoscenza. In ospedale usano la morfina e cannabinoidi sintetici sono già prodotti farmaceutici. Ma le ripeto, il proibizionismo è criminogeno e l'unica cura è la conoscenza. https://t.co/etemgWYqVX

Jul 11, 2020 · 2 likes · 638 followers View post →
Gabriel Gimenez MD
@ggimenezendocri · X

Classical psychedelics for the treatment of depression and anxiety: A ... https://t.co/KwweelifzT psychedelics (asLSD) show sustained beneficial effects for people with depression ir anxyety

Aug 5, 2019 · 2 likes · 523 followers View post →
DMT
@TheDMTCoin · X

New study and systematic review entitled in the Journal of Affective Disorders: “Classical psychedelics for the treatment of depression and anxiety: A systematic review” Concludes: “...psychedelics appear to be… https://t.co/6lex1LfH9f

Aug 6, 2019 · 2 likes · 1 share · 271 followers View post →

All mentions

Cannapedia_io
@Cannapedia_io · X

RT @estarita_javier: @JesMo12 @Alvinsch Cuales son los estudios?, Mira aquí algunos para enriquecer la discusión Cannabis Dolor: https://…

Dec 31, 2021 · 1 share · 2,219 followers View post →
Javier Estarita
@estarita_javier · X

@JesMo12 @Alvinsch Cuales son los estudios?, Mira aquí algunos para enriquecer la discusión Cannabis Dolor: https://t.co/DjltiuFN6W https://t.co/WsLBya4BFx PTSD https://t.co/rseLduMQau Insomnio https://t.co/BpDy6eVmUf Psicodélicos Depresión https://t.co/hDCyVXsiKv TOC https://t.co/rZZSatEqyR

Dec 31, 2021 · 1 like · 1 share · 168 followers View post →
Rem.i.am Syrdidymus
@TSilverSky1 · X

RT @ViewsOnDrugsBot: Classical #psychedelics for the treatment of depression and anxiety: A systematic review 1/5 https://t.co/mhoIPVNH87

Oct 4, 2021 · 3 shares · 166 followers View post →
Views on Drugs
@ViewsOnDrugsBot · X

RT @ViewsOnDrugsBot: Classical #psychedelics for the treatment of depression and anxiety: A systematic review 1/5 https://t.co/mhoIPVNH87

Oct 4, 2021 · 3 shares · 2,060 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @ViewsOnDrugsBot: Classical #psychedelics for the treatment of depression and anxiety: A systematic review 1/5 https://t.co/mhoIPVNH87

Jul 15, 2021 · 3 shares · 6,711 followers View post →
Views on Drugs
@ViewsOnDrugsBot · X

Classical #psychedelics for the treatment of depression and anxiety: A systematic review 1/5 https://t.co/mhoIPVNH87

Jul 15, 2021 · 1 like · 3 shares · 2,060 followers View post →
Nicholas Fulford
@IsoFulford · X

@Novamind_Inc Research into the classical psychedelics - as you know - are showing incredible results. It is a pity that these very useful and potent treatments remained on hold for decades after being driven underground by drug paranoia in the late 1960s. https://t.co/3q7AFAFspy

Mar 20, 2021 · 2 likes · 58 followers View post →
Yazeed
@flexyazeed · X

: مرجع: Classical psychedelics for the treatment of depression and anxiety: A systematic review، https://t.co/vKqTRLjxSc

Aug 30, 2020 · 2 likes · 153 followers View post →
Amsterdam Psychedelic Research Association (APRA)
@APRAresearch · X

Classical psychedelics for the treatment of depression and anxiety: A systematic review. https://t.co/9JrsdfnMHW

Jul 14, 2020 · 2 likes · 4,008 followers View post →
Arrigo Piantavanci
@pat7331 · X

@Alessan67153720 @RijkM73 @Blowjoint @GianpaoL0 @klaudioz83 @AzzurraBarbuto @Mov5Stelle Vede qual è il problema, la chiusura preclude la conoscenza. In ospedale usano la morfina e cannabinoidi sintetici sono già prodotti farmaceutici. Ma le ripeto, il proibizionismo è criminogeno e l'unica cura è la conoscenza. https://t.co/etemgWYqVX

Jul 11, 2020 · 2 likes · 638 followers View post →
Stephen Pimentel
@StephenPiment · X

Classical psychedelics for the treatment of depression and anxiety: A systematic review https://t.co/LLSClxpWuO

Apr 26, 2020 · 12,723 followers View post →
James Hawkins
@DrJamesHawkins · X

Classical psychedelics for the treatment of depression and anxiety: A systematic review. https://t.co/2rffxgzWKB

Jan 9, 2020 · 1,192 followers View post →
Edinburgh Watch
@EdinburghWatch · X

RT @DrJamesHawkins: Classical psychedelics for the treatment of depression and anxiety: A systematic review. https://t.co/eEgmOwFsNf

Jan 4, 2020 · 1 share · 12,020 followers View post →
James Hawkins
@DrJamesHawkins · X

Classical psychedelics for the treatment of depression and anxiety: A systematic review. https://t.co/eEgmOwFsNf

Jan 4, 2020 · 1 share · 1,192 followers View post →
TJ, #FullMetaJacket
@coristus · X

@Cernovich Classical psychedelics for the treatment of depression and anxiety: A systematic review. https://t.co/Bacq1H59aT

Sep 30, 2019 · 2,440 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @APRA_bot: Classical psychedelics for the treatment of depression and anxiety: A systematic review. https://t.co/DbBWryQ8Ze

Aug 9, 2019 · 2 shares · 6,711 followers View post →
TB
@TB47134218 · X

RT @APRA_bot: Classical psychedelics for the treatment of depression and anxiety: A systematic review. https://t.co/DbBWryQ8Ze

Aug 9, 2019 · 2 shares · 3,670 followers View post →
Jorge Herrera
@Georgeudea · X

RT @arnthorjon: #Psychedelic treatments produced significant and sustained #antidepressant and #anxiolytic effects, were well tolerated and…

Aug 6, 2019 · 10 shares · 928 followers View post →
Guia do Psiconauta
@GuiaPsiconauta · X

RT @APRA_bot: Classical psychedelics for the treatment of depression and anxiety: A systematic review. https://t.co/DbBWryQ8Ze

Aug 6, 2019 · 4 shares · 70 followers View post →
Michael Hermann
@MichaelManurun9 · X

RT @APRA_bot: Classical psychedelics for the treatment of depression and anxiety: A systematic review. https://t.co/DbBWryQ8Ze

Aug 6, 2019 · 4 shares · 581 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @decrimcanada: New study and systematic review entitled in the Journal of Affective Disorders: “Classical psychedelics for the treatment…

Aug 6, 2019 · 1 share · 6,711 followers View post →
DMT
@TheDMTCoin · X

New study and systematic review entitled in the Journal of Affective Disorders: “Classical psychedelics for the treatment of depression and anxiety: A systematic review” Concludes: “...psychedelics appear to be… https://t.co/6lex1LfH9f

Aug 6, 2019 · 2 likes · 1 share · 271 followers View post →
Hamish Kibblewhite
@rutjumper · X

RT @arnthorjon: #Psychedelic treatments produced significant and sustained #antidepressant and #anxiolytic effects, were well tolerated and…

Aug 6, 2019 · 10 shares · 231 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @APRA_bot: Classical psychedelics for the treatment of depression and anxiety: A systematic review. https://t.co/DbBWryQ8Ze

Aug 6, 2019 · 4 shares · 6,711 followers View post →
LapisPhilosoforum
@ShamanofDrums · X

RT @APRA_bot: Classical psychedelics for the treatment of depression and anxiety: A systematic review. https://t.co/DbBWryQ8Ze

Aug 6, 2019 · 4 shares · 2,473 followers View post →
Amsterdam Psychedelic Research Association (APRA)
@APRAresearch · X

Classical psychedelics for the treatment of depression and anxiety: A systematic review. https://t.co/DbBWryQ8Ze

Aug 6, 2019 · 2 likes · 4 shares · 4,008 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @painmanwise: Classical psychedelics for the treatment of depression and anxiety: A systematic review. https://t.co/XKvdGanzeO

Aug 6, 2019 · 1 share · 6,711 followers View post →
painmanwise
@painmanwise · X

Classical psychedelics for the treatment of depression and anxiety: A systematic review. https://t.co/XKvdGanzeO

Aug 6, 2019 · 1 share · 227 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @LetOurPeopleGro: Classical psychedelics for the treatment of depression and anxiety: A systematic review https://t.co/atVjfWSOrD

Aug 6, 2019 · 1 share · 6,711 followers View post →
#ChristiansForFREEDOM
@LetOurPeopleGro · X

Classical psychedelics for the treatment of depression and anxiety: A systematic review https://t.co/atVjfWSOrD

Aug 6, 2019 · 1 share · 3,055 followers View post →
DannyMo
@MotykaDanny · X

RT @arnthorjon: #Psychedelic treatments produced significant and sustained #antidepressant and #anxiolytic effects, were well tolerated and…

Aug 5, 2019 · 10 shares · 304 followers View post →
Nicholas
@nicknovak86 · X

RT @arnthorjon: #Psychedelic treatments produced significant and sustained #antidepressant and #anxiolytic effects, were well tolerated and…

Aug 5, 2019 · 10 shares · 499 followers View post →
Lisa Dinkler
@lisadinkler · X

RT @arnthorjon: #Psychedelic treatments produced significant and sustained #antidepressant and #anxiolytic effects, were well tolerated and…

Aug 5, 2019 · 10 shares · 267 followers View post →
Topher Hübel
@topherhuebel · X

RT @arnthorjon: #Psychedelic treatments produced significant and sustained #antidepressant and #anxiolytic effects, were well tolerated and…

Aug 5, 2019 · 10 shares · 1,668 followers View post →
API Studio
@CannaApi · X

RT @arnthorjon: #Psychedelic treatments produced significant and sustained #antidepressant and #anxiolytic effects, were well tolerated and…

Aug 5, 2019 · 10 shares · 953 followers View post →
Gabriel Gimenez MD
@ggimenezendocri · X

Classical psychedelics for the treatment of depression and anxiety: A ... https://t.co/KwweelifzT psychedelics (asLSD) show sustained beneficial effects for people with depression ir anxyety

Aug 5, 2019 · 2 likes · 523 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @arnthorjon: #Psychedelic treatments produced significant and sustained #antidepressant and #anxiolytic effects, were well tolerated and…

Aug 5, 2019 · 10 shares · 6,711 followers View post →
Psychedelic Newsfeed
@PsychedlicNews · X

Classical psychedelics for the treatment of depression and anxiety: A systematic review https://t.co/Urx59eYcWa #psychedelics #LSD #psilocybin #ayahuasca #depression #antidepressants #mentalhealth

Aug 5, 2019 · 1 like · 805 followers View post →
Arnþór
@arnthorjon · X

#Psychedelic treatments produced significant and sustained #antidepressant and #anxiolytic effects, were well tolerated and with no persisting adverse effects. Classical psychedelics for the treatment of #depression and #anxiety: A systematic review https://t.co/k7GR4SiGrj

Aug 5, 2019 · 11 likes · 10 shares · 1,397 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @cannabisRNileen: Classical psychedelics for the treatment of depression and anxiety: A systematic review https://t.co/CBeXR1yYSJ

Aug 4, 2019 · 1 share · 6,711 followers View post →
Eileen Konieczny
@cannabisRNileen · X

Classical psychedelics for the treatment of depression and anxiety: A systematic review https://t.co/CBeXR1yYSJ

Aug 4, 2019 · 1 like · 1 share · 451 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @Afzali_K: Classical psychedelics for the treatment of depression and anxiety: a systematic review - https://t.co/Ukvt95OmzJ #ScholarAle…

Aug 3, 2019 · 1 share · 6,711 followers View post →
Kamran Afzali
@Afzali_K · X

Classical psychedelics for the treatment of depression and anxiety: a systematic review - https://t.co/Ukvt95OmzJ #ScholarAlerts

Aug 3, 2019 · 1 like · 1 share · 148 followers View post →