JAMA Netw Open August 2019 PMID 31461147

Association Between Hormone Therapy and Muscle Mass in Postmenopausal Women: A Systematic Review and Meta-analysis.

Ayesha A Javed, Alexandra J Mayhew, Alison K Shea, Parminder Raina

Mentions

31
Peak: 8 in Aug 2019
across 3 sources since Aug 2019

Extended reach

242,531
potential audience

Total likes

4,052

Video views

70,370

Mentions per month

Aug 2019 – Oct 2025

Where it's discussed

  • News15 articles
  • X / Twitter14 posts
  • YouTube2 videos

AI synopsis

What people are saying

Discussions reflect recognition of the study's conclusion that hormone therapy is not effective in muscle mass retention post-menopause, with posts referencing scientific results and physiological mechanisms, using neutral or slightly contemplative language that indicates cautious acknowledgment rather than controversy or enthusiasm.

AgreementModerate agreement

Most discussions indicate that hormone therapy does not significantly aid in maintaining muscle mass in postmenopausal women, showing general agreement with the publication’s findings.

InterestModerate interest

Participants show moderate interest, as evidenced by technical references and mentions of related physiological concepts, but few express strong curiosity or debate.

EngagementNeutral engagement

The engagement appears moderate, with some posters citing scientific studies and suggesting practical implications, but lacking in detailed analysis or personal insights.

ImpactModerate impact

The shared discussions suggest that the findings may influence clinical perspectives and personal health decisions, though the overall tone remains informational rather than transformative.

Top posts

Most liked on X and Bluesky
GDLeahy
@GDLeahy · X

Association Between Hormone Therapy and Muscle Mass in Postmenopausal Women A Systematic Review and Meta-analysis: https://t.co/EHClkPcBor @EricRawsonPhD @mackinprof @FitGreyStrong @NanciGuestRDPhD

Aug 28, 2019 · 9 likes · 8 shares · 673 followers View post →
Bert Mandelbaum, MD
@MandelbaumMD · X

RT @jamanetworkopen: Systematic review & meta-analysis finds hormone replacement therapy not helpful in muscle mass retention in postmenopausal women. https://t.co/kADqx1Dzqn

Sep 23, 2019 · 2 likes · 1,463 followers View post →
Stuart Phillips (he/him)
@mackinprof · X

@marcelomed76 Women post-menopause & HRT: https://t.co/08wr3Hh8Tl - nothing Women on oral contraceptives: https://t.co/2S8or5cd5Z - potentially negative

Mar 9, 2020 · 1 like · 56,052 followers View post →
シル
@shiru__u · X

@Guesasaurio @diogeneslover @danfromluthadel @Willy_Inkrose Lo de la masa muscular es evidente, a los chicos trans que empiezan a hormonarse de pronto el ejercicio les va mejor, y a las chicas trans al revés. La masa muscular se pierde rapidísimo por los estrógenos. También afectan al uso del glucógeno muscular, sí https://t.co/bGhTzPky1C

Jun 23, 2021 · 1 like · 356 followers View post →
Stuart Phillips (he/him)
@mackinprof · X

RT @GDLeahy: Association Between Hormone Therapy and Muscle Mass in Postmenopausal Women A Systematic Review and Meta-analysis: https://t.c…

Aug 29, 2019 · 8 shares · 56,052 followers View post →
JAMA Network Open
@JAMANetworkOpen · X

Systematic review & meta-analysis finds hormone replacement therapy not helpful in muscle mass retention in postmenopausal women. https://t.co/ZIYvglAZVV

Sep 10, 2019 · 1 share · 25,227 followers View post →

All mentions

Nightfox1090
@nightfox1090 · X

@NotsoArtsyAstra So the hormones used to effect this change alter the bone density and muscle mass of the individual undergoing the procedures which lowers both explosive and prolonged power according to JAMA and AMA (JAMA linked here) https://t.co/845IgSO78y

Feb 15, 2025 · 2,407 followers View post →
シル
@shiru__u · X

@Guesasaurio @diogeneslover @danfromluthadel @Willy_Inkrose Lo de la masa muscular es evidente, a los chicos trans que empiezan a hormonarse de pronto el ejercicio les va mejor, y a las chicas trans al revés. La masa muscular se pierde rapidísimo por los estrógenos. También afectan al uso del glucógeno muscular, sí https://t.co/bGhTzPky1C

Jun 23, 2021 · 1 like · 356 followers View post →
Stuart Phillips (he/him)
@mackinprof · X

@marcelomed76 Women post-menopause & HRT: https://t.co/08wr3Hh8Tl - nothing Women on oral contraceptives: https://t.co/2S8or5cd5Z - potentially negative

Mar 9, 2020 · 1 like · 56,052 followers View post →
Bert Mandelbaum, MD
@MandelbaumMD · X

RT @jamanetworkopen: Systematic review & meta-analysis finds hormone replacement therapy not helpful in muscle mass retention in postmenopausal women. https://t.co/kADqx1Dzqn

Sep 23, 2019 · 2 likes · 1,463 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @JAMANetworkOpen: Systematic review & meta-analysis finds hormone replacement therapy not helpful in muscle mass retention in postmenopa…

Sep 10, 2019 · 1 share · 6,704 followers View post →
JAMA Network Open
@JAMANetworkOpen · X

Systematic review & meta-analysis finds hormone replacement therapy not helpful in muscle mass retention in postmenopausal women. https://t.co/ZIYvglAZVV

Sep 10, 2019 · 1 share · 25,227 followers View post →
MedNewsToday
@today_med · X

!! Association Between #Hormone Therapy and #Muscle Mass in Postmenopausal Women A Systematic Review and Meta-analysis https://t.co/VjSO5zgJbO #medical #medicine

Aug 31, 2019 View post →
Fábio L Orsatti, PhD
@fabiorsatti · X

RT @GDLeahy: Association Between Hormone Therapy and Muscle Mass in Postmenopausal Women A Systematic Review and Meta-analysis: https://t.c…

Aug 29, 2019 · 8 shares · 649 followers View post →
David Scott
@DavidScottPhD · X

RT @GDLeahy: Association Between Hormone Therapy and Muscle Mass in Postmenopausal Women A Systematic Review and Meta-analysis: https://t.c…

Aug 29, 2019 · 8 shares · 2,945 followers View post →
FitGreyStrong
@FitGreyStrong · X

RT @GDLeahy: Association Between Hormone Therapy and Muscle Mass in Postmenopausal Women A Systematic Review and Meta-analysis: https://t.c…

Aug 29, 2019 · 8 shares · 2,298 followers View post →
Nanci Guest PhD, RD, CSCS
@NanciGuestRDPhD · X

RT @GDLeahy: Association Between Hormone Therapy and Muscle Mass in Postmenopausal Women A Systematic Review and Meta-analysis: https://t.c…

Aug 29, 2019 · 8 shares · 10,516 followers View post →
Stuart Phillips (he/him)
@mackinprof · X

RT @GDLeahy: Association Between Hormone Therapy and Muscle Mass in Postmenopausal Women A Systematic Review and Meta-analysis: https://t.c…

Aug 29, 2019 · 8 shares · 56,052 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @GDLeahy: Association Between Hormone Therapy and Muscle Mass in Postmenopausal Women A Systematic Review and Meta-analysis: https://t.c…

Aug 28, 2019 · 8 shares · 6,704 followers View post →
GDLeahy
@GDLeahy · X

Association Between Hormone Therapy and Muscle Mass in Postmenopausal Women A Systematic Review and Meta-analysis: https://t.co/EHClkPcBor @EricRawsonPhD @mackinprof @FitGreyStrong @NanciGuestRDPhD

Aug 28, 2019 · 9 likes · 8 shares · 673 followers View post →