Anesthesiology November 2019 PMID 31490294

Nitrous Oxide Impairs Axon Regeneration after Nervous System Injury in Male Rats.

Krista J Stewart, Bermans J Iskandar, Brenton M Meier, Elias B Rizk, Nithya Hariharan, Joyce Koueik, Adin-Christian Andrei, Kirk J Hogan

Mentions

4
Peak: 1 in Oct 2019
across 3 sources since Oct 2019

Extended reach

2,020
potential audience

Total likes

3

Video views

560

Mentions per month

Oct 2019 – Nov 2019

Where it's discussed

  • Facebook2 posts
  • X / Twitter1 posts
  • YouTube1 videos

AI synopsis

What people are saying

Discussions reflect strong agreement with the research, often emphasizing the detrimental effects of nitrous oxide on nerve regeneration, exemplified by phrases like 'interfere with axonal recovery' and 'raises concerns.' The tone is analytical and cautious, highlighting potential implications for clinical use and public health, which underscores the perceived significance of the study.

AgreementStrong agreement

Most discussions acknowledge and agree with the publication's findings about nitrous oxide impairing nerve regeneration.

InterestModerate interest

While there is general interest in the implications, some users focus mainly on the core findings rather than on broader implications.

EngagementModerate engagement

Several discussions mention specific cellular effects and potential clinical concerns, indicating active engagement.

ImpactHigh impact

The consensus highlights that these findings could influence medical practices and policies regarding nitrous oxide use, suggesting high potential impact.

Abstract in brief

  • Nitrous oxide (N2O) can cause neurotoxicity and impair nerve cell regeneration after injuries to the central nervous system in male rats, both in vitro and in vivo models.
  • A single or repeated exposure to nitrous oxide significantly reduces axon regeneration and reverses the positive effects of folic acid on nerve recovery after injuries like spinal cord and optic nerve trauma.
  • Overall, these findings suggest that nitrous oxide can hinder the nerve's ability to repair itself after injury, which raises concerns about its impact on nervous system recovery.]

Top posts

Most liked on X and Bluesky
Paul
@alassesingollo · X

Nitrous Oxide Impairs Axon Regeneration after Nervous System Injury in Male Rats: These experiments suggest that nitrous oxide can interfere with axonal regeneration and functional recovery following central nervous system injury https://t.co/rXElmwXkqh

Oct 24, 2019 · 1,461 followers View post →

All mentions

Paul
@alassesingollo · X

Nitrous Oxide Impairs Axon Regeneration after Nervous System Injury in Male Rats: These experiments suggest that nitrous oxide can interfere with axonal regeneration and functional recovery following central nervous system injury https://t.co/rXElmwXkqh

Oct 24, 2019 · 1,461 followers View post →