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J Am Coll Cardiol September 2019 PMID 31537271

From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events: JACC State-of-the-Art Review.

Amir Ahmadi, Edgar Argulian, Jonathon Leipsic, David E Newby, Jagat Narula

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Mentions

74
Peak: 11 in Sep 2019
across 5 sources since Sep 2019

Extended reach

1,603,763
potential audience

Total likes

24,283

Video views

1,252,127

Mentions per month

Sep 2019 – Dec 2025

Where it's discussed

  • X / Twitter63 posts
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  • Facebook2 posts
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AI synopsis

What people are saying

The overall tone reflects strong agreement and interest, with discussions highlighting the potential of noninvasive imaging and screening methods, such as ultrasound, to transform prevention strategies. Participants employ confident language like 'excellent article' and 'important lessons,' demonstrating their deep engagement and recognition of the publication’s potential impact on future cardiology practices.

AgreementStrong agreement

Most discussions support the findings and importance of early detection and intervention of atherosclerosis, emphasizing consensus with the publication's conclusions.

InterestHigh interest

The discussions focus heavily on the significance of early screening, noninvasive imaging, and implications for treatment, indicating high interest.

EngagementModerate engagement

Many participants reference specific studies, methods like artery screening, and clinical practices, demonstrating moderate to deep engagement.

ImpactHigh impact

The discourse suggests that the article could influence clinical practices, especially related to early detection strategies and personalized treatments, indicating high impact.

Abstract in brief

  • The review explains that most acute coronary events are linked to the rapid growth of nonobstructive plaques, rather than solely from the rupture of already-stenotic plaque, highlighting the importance of plaque progression in causing heart attacks.
  • Noninvasive imaging methods like CT angiography have confirmed that plaques which do not grow significantly over time rarely lead to coronary events, and that slowing or halting plaque growth with intensive lipid-lowering therapy can prevent plaque rupture.
  • The authors suggest that early detection of atherosclerosis and targeting plaque progression through personalized treatment could improve prevention strategies, moving beyond traditional risk assessment toward more tailored, effective management of cardiovascular disease.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Gil Carvalho MD PhD
@NutritionMadeS3 · X

https://t.co/QjX9S2O9eG

Nov 20, 2023 · 46 likes · 3 shares · 27,736 followers View post →
OPCI
@OPCILive · X

During this week's Journal Club, @LubbDup discusses "From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events". To watch the entire discussion: https://t.co/f7G5ALcrRz @ziadalinyc @Antocol17 @djc795 @JWMoses @DrAllenJ @ESHLOF https://t.co/efvj7pdwkh

Feb 19, 2022 · 21 likes · 8 shares · 1,706 followers View post →
Michael Albert, MD
@MichaelAlbertMD · X

“On the other hand, it has been convincingly demonstrated that intensive lipid-lowering therapy (to a low-density lipoprotein cholesterol level of <70 mg/dl) halts plaque progression.” Everyone should be less than 70! H/t ⁦@NutritionMadeS3⁩ https://t.co/V7Z6T9fncP

Jun 14, 2022 · 13 likes · 2 shares · 15,908 followers View post →
Joseph A. Daibes, DO
@drdaibes · X

Excellent review article from Dr Amir Ahmadi, and @argulian From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events JACC State-of-the-Art Review https://t.co/YWVjGYE9yR

Sep 17, 2019 · 6 likes · 1 share · 406 followers View post →
ماجد الحريبي | صيدلي
@majedalhoriby · X

From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events JACC 2019 https://t.co/NiVR9zYO1a

Oct 3, 2019 · 5 likes · 1 share · 51,091 followers View post →
YourArteries.net
@yourarteries · X

@AnnMarieNavar @ericpetersonMD Or better yet, "treat the disease rather than the likelihood of disease," as five cardiologists recommended in this JACC State-of-the-Art review, by screening people for early-stage atherosclerosis: https://t.co/vc7e1UPXEY

Aug 23, 2022 · 4 likes · 1 share · 7 followers View post →

All mentions

KaizenPerformance
@KaizenPerf · X

"This Exercise shrinks PLAQUE in your arteries (!) | New trial" https://t.co/m853FSnTUx

Feb 20, 2025 · 306 followers View post →
BedrosGesaratsian ֍Ⓥ
@gesaratsian · X

@joycloete @MohammedAlo It depends on the individual but I would say many months if not years. For example, a 1.2% reduction in 6 months: ⬇️ https://t.co/wau7EqOMqu

Jan 10, 2025 · 536 followers View post →
Gil Carvalho MD PhD
@NutritionMadeS3 · X

@Ro11TideGirl yes, some studies indicate some regression. there are trials using exercise, diet and medication. the degree of regression is usually modest although it's associated with a very significant risk reduction https://t.co/QjX9S2NBp8

Apr 8, 2024 · 27,736 followers View post →
AXELIFE
@AXELIFE_fr · X

From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events: JACC State-of-the-Art Review - ScienceDirect | @scoopit https://t.co/r4z4IlG2yx

Mar 14, 2024 · 199 followers View post →
Jerry Dean Bowers
@vipertoxin · X

» (174) This Exercise shrinks PLAQUE in your arteries (!) | New trial - YouTube https://t.co/gRLRaX04Yv

Nov 29, 2023 · 555 followers View post →
Mööp
@Meoeop · X

RT @NutritionMadeS3: https://t.co/QjX9S2O9eG

Nov 21, 2023 · 3 shares · 274 followers View post →
Science With Sanjay
@SanjayScience · X

RT @NutritionMadeS3: https://t.co/QjX9S2O9eG

Nov 20, 2023 · 3 shares · 183 followers View post →
Victoria VALPARAISO
@Orange_Atomique · X

RT @NutritionMadeS3: https://t.co/QjX9S2O9eG

Nov 20, 2023 · 3 shares · 180 followers View post →
Gil Carvalho MD PhD
@NutritionMadeS3 · X

https://t.co/QjX9S2O9eG

Nov 20, 2023 · 46 likes · 3 shares · 27,736 followers View post →
Scott Servilla
@scstse · X

@RFRedberg Or at least personalized medicine using angiogpraphy to detect and prevent plaque progression instead of treating every case of hyperlipidemia like a nail and statins the only hammer? https://t.co/xDkJLdkqlz

Jun 26, 2023 · 101 followers View post →
Das
@shivadas29 · X

@Umair2017 @MichaelJBlaha Plaque microstructures during metformin therapy in type 2 diabetic subjects with coronary artery disease: optical coherence tomography analysis 2022 https://t.co/X9AbQxlZz1

Oct 11, 2022 · 387 followers View post →
Das
@ssdas29 · X

@Umair2017 @MichaelJBlaha Plaque microstructures during metformin therapy in type 2 diabetic subjects with coronary artery disease: optical coherence tomography analysis 2022 https://t.co/X9AbQxlZz1

Oct 11, 2022 · 396 followers View post →
Yeiscimin Escobedo
@YeisciminE · X

Sep 4, 2022 · 1,482 followers View post →
Simon Brežan MD
@BrezanSimonMD · X

https://t.co/xHv0V39OfA #CardioTwitter #MedTwitter #CVD https://t.co/Ci6UTeJl2i

Aug 26, 2022 · 783 followers View post →
Meded
@cryptovitas · X

RT @BrezanSimonMD: From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events: JACC State-of-the-Art Review Importan…

Aug 26, 2022 · 1 share · 3,180 followers View post →
Simon Brežan MD
@BrezanSimonMD · X

From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events: JACC State-of-the-Art Review Important lessons for redefin of #prevention, screening and early LLT th for subclin #atherosclerosis https://t.co/xHv0V2RF1s #CardioTwitter #MedTwitter #CVD

Aug 26, 2022 · 1 like · 1 share · 783 followers View post →
Linda
@wordfinga · X

RT @yourarteries: @AnnMarieNavar @ericpetersonMD Or better yet, "treat the disease rather than the likelihood of disease," as five cardiolo…

Aug 24, 2022 · 1 share · 4,598 followers View post →
YourArteries.net
@yourarteries · X

@AnnMarieNavar @ericpetersonMD Or better yet, "treat the disease rather than the likelihood of disease," as five cardiologists recommended in this JACC State-of-the-Art review, by screening people for early-stage atherosclerosis: https://t.co/vc7e1UPXEY

Aug 23, 2022 · 4 likes · 1 share · 7 followers View post →
YourArteries.net
@yourarteries · X

@drscottyk .@drscottyk Artery screening to detect early-stage atherosclerosis, as recommended at https://t.co/AGNHTJE1MW, is the subject of my slim draft book available at https://t.co/7XTN4QxMGs. I seek a cardiologist to partner on improving the book to reach a wider public audience.

Aug 21, 2022 · 7 followers View post →
YourArteries.net
@yourarteries · X

@cardiojaydoc02 Why not the low-cost, noninvasive carotid artery ultrasound? Five cardiologists have proposed that doctors test people for clogged arteries, using that test or any of three others, and offer those found to have clogged arteries a statin prescription. https://t.co/vc7e1UPXEY

Aug 15, 2022 · 7 followers View post →
YourArteries.net
@yourarteries · X

.@DrLipid Artery screening to detect early-stage atherosclerosis, as recommended at https://t.co/zzau11bUCw, is the subject of my slim draft book available free at https://t.co/7XTN4QxMGs. I seek a cardiologist to partner on improving the book to reach a wider public audience.

Aug 12, 2022 · 7 followers View post →
Gil Carvalho MD PhD
@NutritionMadeS3 · X

@thoroughlyconf1 @maximumcharacte @DrNadolsky https://t.co/5x1vBRDK41 https://t.co/sB3xTJ6htQ

Aug 9, 2022 · 27,749 followers View post →
YourArteries.net
@yourarteries · X

.@Dr_DanMD Artery screening to detect early-stage atherosclerosis, as recommended at https://t.co/zzau11bUCw, is the subject of my slim draft book available at https://t.co/7XTN4QxMGs. I seek a cardiologist to partner on improving the book to reach a wider public audience.

Jul 31, 2022 · 7 followers View post →
YourArteries.net
@yourarteries · X

.@AmitGoyalMD Artery screening to detect early-stage atherosclerosis, as recommended at https://t.co/zzau10UjdW, is the subject of my slim draft book available at https://t.co/7XTN4QPny0. I seek a cardiologist to partner on improving the book to reach a wider public audience.

Jul 31, 2022 · 7 followers View post →
YourArteries.net
@yourarteries · X

.@CardioNerds Artery screening to detect early-stage atherosclerosis, as recommended at https://t.co/zzau11bUCw, is the subject of my slim draft book available at https://t.co/7XTN4QxMGs. I seek a cardiologist to partner on improving the book to reach a wider public audience.

Jul 31, 2022 · 7 followers View post →
YourArteries.net
@yourarteries · X

.@SethJBaumMD Artery screening to detect early-stage atherosclerosis, as recommended at https://t.co/AGNHTJE1MW, is the subject of my slim draft book available at https://t.co/7XTN4QxMGs. I seek a cardiologist to partner on improving the book to reach a wider public audience.

Jul 24, 2022 · 7 followers View post →
YourArteries.net
@yourarteries · X

.@dramitkhera Artery screening to detect early-stage atherosclerosis, as recommended at https://t.co/AGNHTJE1MW, is the subject of my slim draft book available at https://t.co/7XTN4QxMGs. I seek a cardiologist to partner on improving the book to reach a wider public audience.

Jul 24, 2022 · 7 followers View post →
YourArteries.net
@yourarteries · X

'@AnumSaeedMD Artery screening to detect early-stage atherosclerosis, as recommended at https://t.co/AGNHTJE1MW, is the subject of my slim draft book available at https://t.co/7XTN4QxMGs. I seek a cardiologist to partner on improving the book to reach a wider public audience.

Jul 18, 2022 · 7 followers View post →
YourArteries.net
@yourarteries · X

'@KoushikReddyMD Artery screening to detect early-stage atherosclerosis, as recommended at https://t.co/AGNHTJE1MW, is the subject of my slim draft book available at https://t.co/7XTN4QxMGs. I seek a cardiologist to partner on improving the book to reach a wider public audience.

Jul 18, 2022 · 7 followers View post →
YourArteries.net
@yourarteries · X

'@DrOstfeld Artery screening to detect early-stage atherosclerosis, as recommended at https://t.co/AGNHTJE1MW, is the subject of my slim draft book available at https://t.co/7XTN4QxMGs. I seek a cardiologist to partner on improving the book to reach a wider public audience.

Jul 18, 2022 · 7 followers View post →
YourArteries.net
@yourarteries · X

'@kcferdmd Artery screening to detect early-stage atherosclerosis, as recommended at https://t.co/AGNHTJE1MW, is the subject of my slim draft book available at https://t.co/7XTN4QxMGs. I seek a cardiologist to partner on improving the book to reach a wider public audience.

Jul 18, 2022 · 7 followers View post →
YourArteries.net
@yourarteries · X

'@ronblankstein Artery screening to detect early-stage atherosclerosis, as recommended at https://t.co/AGNHTJE1MW, is the subject of my slim draft book available at https://t.co/7XTN4QxMGs. I seek a cardiologist to partner on improving the book to reach a wider public audience.

Jul 18, 2022 · 7 followers View post →
YourArteries.net
@yourarteries · X

'@ErinMichos Artery screening to detect early-stage atherosclerosis, as recommended at https://t.co/AGNHTJE1MW, is the subject of my slim draft book available at https://t.co/7XTN4QxMGs. I seek a cardiologist to partner on improving the book to reach a wider public audience.

Jul 18, 2022 · 7 followers View post →
Alvaro Reyes
@aerq_md · X

RT @MichaelAlbertMD: “On the other hand, it has been convincingly demonstrated that intensive lipid-lowering therapy (to a low-density lipo…

Jun 14, 2022 · 2 shares · 74 followers View post →
David E. Albert, M.D
@DrDave01 · X

RT @MichaelAlbertMD: “On the other hand, it has been convincingly demonstrated that intensive lipid-lowering therapy (to a low-density lipo…

Jun 14, 2022 · 2 shares · 16,538 followers View post →
Michael Albert, MD
@MichaelAlbertMD · X

“On the other hand, it has been convincingly demonstrated that intensive lipid-lowering therapy (to a low-density lipoprotein cholesterol level of <70 mg/dl) halts plaque progression.” Everyone should be less than 70! H/t ⁦@NutritionMadeS3⁩ https://t.co/V7Z6T9fncP

Jun 14, 2022 · 13 likes · 2 shares · 15,908 followers View post →
Gil Carvalho MD PhD
@NutritionMadeS3 · X

@Nutradvance @FrogHarmless btw this is the evidence I´m referring to re: lowering it enough stops plaque growth: https://t.co/sB3xTJnSSq

Jun 14, 2022 · 2 likes · 27,749 followers View post →
Gil Carvalho MD PhD
@NutritionMadeS3 · X

@PeterFaberSP in general if apoB is truly low plaque does not grow (or very slowly), may even reverse a bit. maybe there are exceptions like people with high lp(a) https://t.co/sB3xTJnSSq

May 20, 2022 · 1 like · 27,749 followers View post →
@APSIC
@APSIC6 · X

RT @OPCILive: During this week's Journal Club, @LubbDup discusses "From Subclinical Atherosclerosis to Plaque Progression and Acute Coronar…

Feb 20, 2022 · 8 shares · 1,535 followers View post →
sajannarayanan
@sajannarayanan · X

RT @OPCILive: During this week's Journal Club, @LubbDup discusses "From Subclinical Atherosclerosis to Plaque Progression and Acute Coronar…

Feb 19, 2022 · 8 shares · 964 followers View post →
Hiteshi KC Chauhan
@HiteshiKc · X

RT @OPCILive: During this week's Journal Club, @LubbDup discusses "From Subclinical Atherosclerosis to Plaque Progression and Acute Coronar…

Feb 19, 2022 · 8 shares · 440 followers View post →
Fernando A Sosa
@FernanOCT · X

RT @OPCILive: During this week's Journal Club, @LubbDup discusses "From Subclinical Atherosclerosis to Plaque Progression and Acute Coronar…

Feb 19, 2022 · 8 shares · 346 followers View post →
Antonious Attallah, MD, FACC, FSCAI
@AntoniousAttall · X

RT @OPCILive: During this week's Journal Club, @LubbDup discusses "From Subclinical Atherosclerosis to Plaque Progression and Acute Coronar…

Feb 19, 2022 · 8 shares · 9,762 followers View post →
Ziad Ali
@ziadalinyc · X

RT @OPCILive: During this week's Journal Club, @LubbDup discusses "From Subclinical Atherosclerosis to Plaque Progression and Acute Coronar…

Feb 19, 2022 · 8 shares · 12,231 followers View post →
Evan Shlofmitz
@ESHLOF · X

RT @OPCILive: During this week's Journal Club, @LubbDup discusses "From Subclinical Atherosclerosis to Plaque Progression and Acute Coronar…

Feb 19, 2022 · 8 shares · 1,559 followers View post →
David J. Cohen, MD, MSc
@djc795 · X

RT @OPCILive: During this week's Journal Club, @LubbDup discusses "From Subclinical Atherosclerosis to Plaque Progression and Acute Coronar…

Feb 19, 2022 · 8 shares · 18,818 followers View post →
OPCI
@OPCILive · X

During this week's Journal Club, @LubbDup discusses "From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events". To watch the entire discussion: https://t.co/f7G5ALcrRz @ziadalinyc @Antocol17 @djc795 @JWMoses @DrAllenJ @ESHLOF https://t.co/efvj7pdwkh

Feb 19, 2022 · 21 likes · 8 shares · 1,706 followers View post →
Gil Carvalho MD PhD
@NutritionMadeS3 · X

@PeterFaberSP @OlivePufa except if you push LDL-c/ApoB low enough, you halt and possibly even reverse plaque growth https://t.co/sB3xTJnSSq so elevated ApoB is indeed the causal crux. now if they develop other interventions that stop retention even with high ApoB, that could work too

Jan 31, 2022 · 1 like · 27,749 followers View post →
Gil Carvalho MD PhD
@NutritionMadeS3 · X

@paulkinkade @ScepticalDoctor @brimbporter @nutrition_facts 150 TC corresponds roughly to ~70 LDL-c, where plaque progression is halted https://t.co/sB3xTJnSSq so it should prevent HD. BUT if i already HAVE it, i may need to go even lower stylistically I would NOT use that language - "immune to" - nowadays. hype-ish and can be unclear

Jan 29, 2022 · 1 like · 27,749 followers View post →
Adams CardioMD
@AdamsCardioMD · X

From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events https://t.co/O94grXS5n8

Oct 20, 2019 · 607 followers View post →
Dr Maged Shurrab
@msshurrab · X

RT @majedalhoriby: From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events JACC 2019 https://t.co/NiVR9zYO1a

Oct 3, 2019 · 1 share · 1,192 followers View post →
ماجد الحريبي | صيدلي
@majedalhoriby · X

From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events JACC 2019 https://t.co/NiVR9zYO1a

Oct 3, 2019 · 5 likes · 1 share · 51,091 followers View post →
aarthi madhanakumar
@aarthimadhan · X

RT @victorfarah75: From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events https://t.co/6SaJVNQtDQ

Sep 29, 2019 · 1 share · 98 followers View post →
Victor Farah, MD
@victorfarah75 · X

From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events https://t.co/6SaJVNQtDQ

Sep 29, 2019 · 1 like · 1 share · 279 followers View post →
Alex Kharlamov MD FESC FACC FEACVI
@drskharlamov · X

RT @drskharlamov: From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events | JACC https://t.co/OIG9pcvlte

Sep 26, 2019 · 1 share · 1,676 followers View post →
Alex Kharlamov MD FESC FACC FEACVI
@drskharlamov · X

From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events | JACC https://t.co/OIG9pcvlte

Sep 26, 2019 · 1 like · 1 share · 1,676 followers View post →
ctca_papers
@ctcapapers1 · X

From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events: JACC State-of-the-Art Review. https://t.co/0ROrGVlyPu

Sep 22, 2019 · 104 followers View post →
Dr. John A Rumberger, PhD, MD, FACC, MSCCT
@DrRumberger · X

From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events https://t.co/oITWbB70em although the ACC always make the model of ASO too simple, forgetting remodeling and minimal lumen narrowing as the major culprit - this is an excellent article

Sep 18, 2019 · 2,437 followers View post →
Adams CardioMD
@AdamsCardioMD · X

From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events https://t.co/O94grXS5n8

Sep 18, 2019 · 607 followers View post →
Georgeta Vaidean
@georgeta · X

Will early ASC detection/imagistics redefine the traditional paradigm of #CvPrev based on population-derived risk estimates? >>>"From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events" https://t.co/6tKItge5gH https://t.co/z1Hu1pjbqU

Sep 17, 2019 · 380 followers View post →
Aditya A Joshi
@AdvancedHFBuddy · X

RT @drdaibes: Excellent review article from Dr Amir Ahmadi, and @argulian From Subclinical Atherosclerosis to Plaque Progression and Acute…

Sep 17, 2019 · 1 share · 1,766 followers View post →
Joseph A. Daibes, DO
@drdaibes · X

Excellent review article from Dr Amir Ahmadi, and @argulian From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events JACC State-of-the-Art Review https://t.co/YWVjGYE9yR

Sep 17, 2019 · 6 likes · 1 share · 406 followers View post →
Dataemia
@Dataemia · X

From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events: JACC State-of-the-Art Review - https://t.co/gfSpfwsRnO https://t.co/hUkYvhPG30

Sep 16, 2019 · 969 followers View post →