J Neurogastroenterol Motil October 2019 PMID 31587548

A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.

Sumire Mori, Toshihiko Tomita, Kazuki Fujimura, Haruki Asano, Tomohiro Ogawa, Takahisa Yamasaki, Takashi Kondo, Tomoaki Kono, Katsuyuki Tozawa, Tadayuki Oshima, Hirokazu Fukui, Takeshi Kimura, Jiro Watari, Hiroto Miwa

Download social card

Mentions

12
Peak: 5 in Jun 2020
across 3 sources since Dec 2019

Extended reach

40,284
potential audience

Total likes

745

Video views

10,169

Mentions per month

Dec 2019 – Jan 2026

Where it's discussed

  • X / Twitter9 posts
  • YouTube2 videos
  • Reddit1 posts

AI synopsis

What people are saying

Several posts focus on the study's findings, such as magnesium oxide improving bowel transit time and overall bowel movements, indicating active interest and engagement. The tone varies from supportive to analytical, with mentions of how this research could influence treatment options, which underscores a recognition of its potential impact in clinical practice.

AgreementModerate agreement

Most discussions acknowledge the positive findings about magnesium oxide improving bowel movements and transit time, indicating general support for the study's conclusions.

InterestHigh interest

Interest in the topic is high, with many posts referencing specific results like increased transit time and stool improvements, suggesting curiosity and relevance.

EngagementModerate engagement

Posts often delve into details such as effects on colonic transit or treatment implications, showing moderate to deep engagement.

ImpactModerate impact

Some discussions highlight the potential clinical importance of magnesium oxide as a treatment, reflecting moderate recognition of its significance.

Abstract in brief

  • This study tested whether magnesium oxide (MgO) helps Japanese women with mild to moderate chronic constipation, finding it improved bowel movements, stool form, colonic transit time, and quality of life compared to a placebo.
  • The results showed that around 70% of patients taking MgO had overall improvement, significantly better than 25% in the placebo group, and MgO also increased spontaneous bowel movements and improved stool form and transit time.
  • However, MgO didn’t significantly increase complete spontaneous bowel movement response rates, but it was effective in making bowel movements better and quicker, suggesting it’s a beneficial treatment for managing chronic constipation.]

Top posts

Most liked on X and Bluesky
青島周一
@syuichiao89 · X

A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation https://t.co/WoYdEwUylL

Jun 28, 2020 · 7 likes · 5 shares · 8,608 followers View post →
青島周一
@syuichiao89 · X

健常者に酸化マグネシウムを臨床用量で投与したらわりと大変やで

Apr 30, 2024 · 4 likes · 8,608 followers View post →
猫になりたい薬剤師
@Vannyamoto · X

答え:2019年 https://t.co/b0WYNBNKiX 古くから使用されている薬では臨床試験が実施されていないことがあります。承認プロセスが未成熟だったこともありますが、実臨床での実績があるためです。 一方で、改めて臨床試験を実施したところ効果がないこともあります。いずれにせよ盲信には注意です。

Feb 14, 2025 · 1 like · 1,045 followers View post →
山本雄一郎(薬局薬学のエディター)
@kumamotoPh · X

RT @syuichiao89: A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation…

Jun 28, 2020 · 5 shares · 7,634 followers View post →
Dr.Avocado
@k1h · X

RT @syuichiao89: A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation…

Jun 28, 2020 · 5 shares · 3,617 followers View post →
Yossef
@hazetemple · X

RT @syuichiao89: A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation…

Jun 28, 2020 · 5 shares · 337 followers View post →

All mentions

猫になりたい薬剤師
@Vannyamoto · X

答え:2019年 https://t.co/b0WYNBNKiX 古くから使用されている薬では臨床試験が実施されていないことがあります。承認プロセスが未成熟だったこともありますが、実臨床での実績があるためです。 一方で、改めて臨床試験を実施したところ効果がないこともあります。いずれにせよ盲信には注意です。

Feb 14, 2025 · 1 like · 1,045 followers View post →
青島周一
@syuichiao89 · X

健常者に酸化マグネシウムを臨床用量で投与したらわりと大変やで

Apr 30, 2024 · 4 likes · 8,608 followers View post →
ExceptionalND
@Exceptional_ND · X

MAGNESIUM OXIDE (MgO) improves colonic transit time by 19 hrs❗️

Apr 13, 2023 · 97 followers View post →
SleepPapers
@PapersSleep · X

A randomized, double-blind, placebo-controlled trial on the effect of intranasal corticosteroid as a treatment for moderate to severe obstructive sleep apnea with coexisting chronic rhinitis. https://t.co/PjM6xRGNen https://t.co/dHSQhXdxEV

Aug 24, 2020 · 98 followers View post →
山本雄一郎(薬局薬学のエディター)
@kumamotoPh · X

RT @syuichiao89: A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation…

Jun 28, 2020 · 5 shares · 7,634 followers View post →
げんしー
@genshi_genshi · X

RT @syuichiao89: A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation…

Jun 28, 2020 · 5 shares · 12 followers View post →
Dr.Avocado
@k1h · X

RT @syuichiao89: A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation…

Jun 28, 2020 · 5 shares · 3,617 followers View post →
Yossef
@hazetemple · X

RT @syuichiao89: A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation…

Jun 28, 2020 · 5 shares · 337 followers View post →
青島周一
@syuichiao89 · X

A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation https://t.co/WoYdEwUylL

Jun 28, 2020 · 7 likes · 5 shares · 8,608 followers View post →
Constipation Treatment that Works - also linked to milk allergy ...
Reddit

... 10.5056/jnm18194 A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.

Dec 28, 2019 View →