Front Immunol October 2020 PMID 31620139

Increased T Cell Differentiation and Cytolytic Function in Bangladeshi Compared to American Children.

Lisa E Wagar, Christopher R Bolen, Natalia Sigal, Cesar J Lopez Angel, Leying Guan, Beth D Kirkpatrick, Rashidul Haque, Robert J Tibshirani, Julie Parsonnet, William A Petri, Mark M Davis

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Mentions

18
Peak: 9 in Sep 2019
across 2 sources since Sep 2019

Extended reach

58,524
potential audience

Total likes

38

Video views

398

Mentions per month

Sep 2019 – Feb 2021

Where it's discussed

  • X / Twitter16 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions predominantly support the study's conclusions, with comments like 'Great paper' and references to notable researchers, demonstrating appreciation and validation. Technical mentions of tools and data analysis approaches reflect a level of detailed engagement, and the tone emphasizes the importance of understanding immune differences in children from different environments, contributing to a moderate impact perception.

AgreementModerate agreement

Most posts express positive reactions, praising the study and its authors, indicating agreement with the significance of the findings.

InterestModerate interest

Discussions show curiosity about the immunological differences and their implications, reflecting moderate interest.

EngagementHigh engagement

Multiple posts reference specific methods, tools like Astrolabe, and commendations on the research, showing deep engagement.

ImpactModerate impact

Posts highlight the potential importance of the findings for immunology and public health, suggesting the study could influence future research and understanding.

Abstract in brief

  • The study compares the immune responses of children from Bangladesh and the USA, finding that Bangladeshi children show increased T cell differentiation and cytolytic activity by age 2-3, indicating a more mature or activated immune system compared to American children.
  • Despite similar immune characteristics at 1 year of age, differences emerge over time, with Bangladeshi children exhibiting altered immune activation and cytokine profiles, possibly reflecting adaptation to a higher microbial environment.
  • Factors like ethnicity, microbial exposure, and health conditions such as stunting influence immune variations, highlighting the roles of IL8 and TGF in helping Bangladeshi children respond to microbial challenges.]

Top posts

Most liked on X and Bluesky
Petter Brodin
@BrodinPetter · X

Great paper, congrats to Lisa Wagar, the Davis lab et al - Increased T Cell Differentiation and Cytolytic Function in Bangladeshi Compared to American Children https://t.co/d5xJI3Vz8c

Sep 22, 2019 · 29 likes · 7 shares · 13,038 followers View post →
Frontiers - Immunology
@FrontImmunol · X

New Research: Increased T Cell Differentiation and Cytolytic Function in Bangladeshi Compared to American Children: During the first 5 years of life, children are especially vulnerable to infection-related morbidity and mortality. Conversely,… https://t.co/9zhXQHFRbi #immunology

Oct 18, 2019 · 2 likes · 1 share · 33,762 followers View post →
Astrolabe Diagnostics, Inc.
@astrolabediag · X

Come see how Astrolabe analyzes the data from Wagar et al. (https://t.co/9PpCJ3ERzk) and reproduces some of their results -- in ten minutes of work! https://t.co/rBmAtfIPsd #MassCytometry #ImmuneSystem #Immunology #Cytometry

Sep 23, 2019 · 2 likes · 1 share · 149 followers View post →
Cytof Manchester
@ManchesterCytof · X

Increased T Cell Differentiation and Cytolytic Function in Bangladeshi Compared to American Children https://t.co/iXfeaZui1w #cytofpub

Oct 21, 2019 · 1 like · 555 followers View post →
Cytof Manchester
@ManchesterCytof · X

Frontiers | Increased T Cell Differentiation and Cytolytic Function in Bangladeshi Compared to American Children | Immunology #cytofpub https://t.co/9bCinaoT21

Sep 20, 2019 · 1 like · 1 share · 555 followers View post →
UVA Science Pubs
@UvaScience_Pubs · X

Increased T Cell Differentiation and Cytolytic Function in Bangladeshi Compared to American Children. https://t.co/q3KxSb63yN https://t.co/EWIN11f64a

Oct 23, 2020 · 1 like · 260 followers View post →

All mentions

Astrolabe Diagnostics, Inc.
@astrolabediag · X

#Astrolabe supports customization of the labeling hierarchy which allows correct classification of any particular subsets in your panel https://t.co/DwqkhHibK5 #SingleCells #ImmuneMonitoring

Feb 24, 2021 · 149 followers View post →
UVA Science Pubs
@UvaScience_Pubs · X

Increased T Cell Differentiation and Cytolytic Function in Bangladeshi Compared to American Children. https://t.co/q3KxSb63yN https://t.co/EWIN11f64a

Oct 23, 2020 · 1 like · 260 followers View post →
Cytof Manchester
@ManchesterCytof · X

Increased T Cell Differentiation and Cytolytic Function in Bangladeshi Compared to American Children https://t.co/iXfeaZui1w #cytofpub

Oct 21, 2019 · 1 like · 555 followers View post →
David Ochayon
@DOchayon · X

RT @FrontImmunol: New Research: Increased T Cell Differentiation and Cytolytic Function in Bangladeshi Compared to American Children: Durin…

Oct 18, 2019 · 1 share · 288 followers View post →
Frontiers - Immunology
@FrontImmunol · X

New Research: Increased T Cell Differentiation and Cytolytic Function in Bangladeshi Compared to American Children: During the first 5 years of life, children are especially vulnerable to infection-related morbidity and mortality. Conversely,… https://t.co/9zhXQHFRbi #immunology

Oct 18, 2019 · 2 likes · 1 share · 33,762 followers View post →
UVA Science Pubs
@UvaScience_Pubs · X

Increased T Cell Differentiation and Cytolytic Function in Bangladeshi Compared to American Children. https://t.co/CNHbHg05km

Oct 18, 2019 · 1 like · 260 followers View post →
Frontiers - Infectious Disease
@FrontInfectDis · X

RT @ManchesterCytof: Frontiers | Increased T Cell Differentiation and Cytolytic Function in Bangladeshi Compared to American Children | Imm…

Oct 8, 2019 · 1 share · 3,824 followers View post →
Patrick Dunn
@biocoimeadai · X

RT @BrodinPetter: Great paper, congrats to Lisa Wagar, the Davis lab et al - Increased T Cell Differentiation and Cytolytic Function in Ban…

Oct 1, 2019 · 7 shares · 362 followers View post →
ImmunoConcept
@ImmunoConcept · X

RT @BrodinPetter: Great paper, congrats to Lisa Wagar, the Davis lab et al - Increased T Cell Differentiation and Cytolytic Function in Ban…

Sep 25, 2019 · 7 shares · 546 followers View post →
Astrolabe Diagnostics, Inc.
@astrolabediag · X

Come see how Astrolabe analyzes the data from Wagar et al. (https://t.co/9PpCJ3ERzk) and reproduces some of their results -- in ten minutes of work! https://t.co/rBmAtfIPsd #MassCytometry #ImmuneSystem #Immunology #Cytometry

Sep 23, 2019 · 2 likes · 1 share · 149 followers View post →
Maria Jenmalm
@mjnmlm · X

RT @BrodinPetter: Great paper, congrats to Lisa Wagar, the Davis lab et al - Increased T Cell Differentiation and Cytolytic Function in Ban…

Sep 23, 2019 · 7 shares · 942 followers View post →
eric hoyeon song
@ericsongg · X

RT @BrodinPetter: Great paper, congrats to Lisa Wagar, the Davis lab et al - Increased T Cell Differentiation and Cytolytic Function in Ban…

Sep 22, 2019 · 7 shares · 1,551 followers View post →
HIPC
@hipcProject · X

RT @BrodinPetter: Great paper, congrats to Lisa Wagar, the Davis lab et al - Increased T Cell Differentiation and Cytolytic Function in Ban…

Sep 22, 2019 · 7 shares · 1,356 followers View post →
Chirag Krishna
@chirag_msk · X

RT @BrodinPetter: Great paper, congrats to Lisa Wagar, the Davis lab et al - Increased T Cell Differentiation and Cytolytic Function in Ban…

Sep 22, 2019 · 7 shares · 422 followers View post →
Petter Brodin
@BrodinPetter · X

Great paper, congrats to Lisa Wagar, the Davis lab et al - Increased T Cell Differentiation and Cytolytic Function in Bangladeshi Compared to American Children https://t.co/d5xJI3Vz8c

Sep 22, 2019 · 29 likes · 7 shares · 13,038 followers View post →
Cytof Manchester
@ManchesterCytof · X

Frontiers | Increased T Cell Differentiation and Cytolytic Function in Bangladeshi Compared to American Children | Immunology #cytofpub https://t.co/9bCinaoT21

Sep 20, 2019 · 1 like · 1 share · 555 followers View post →