Dermatol Ther (Heidelb) February 2020 PMID 31686337

Rapid Response of Biologic Treatments of Moderate-to-Severe Plaque Psoriasis: A Comprehensive Investigation Using Bayesian and Frequentist Network Meta-analyses.

Richard B Warren, Kyoungah See, Russel Burge, Ying Zhang, Alan Brnabic, Gaia Gallo, Alyssa Garrelts, Alexander Egeberg

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Mentions

10
Peak: 3 in Dec 2019
across 3 sources since Nov 2019

Extended reach

26,362
potential audience

Total likes

19

Video views

1,214

Mentions per month

Nov 2019 – Nov 2020

Where it's discussed

  • X / Twitter7 posts
  • News2 articles
  • YouTube1 videos

AI synopsis

What people are saying

Discussions express strong agreement with the article, especially regarding the rapid action of biologics like ixekizumab and brodalumab, using words like 'most rapid response' and phrases such as 'transforming treatment.' Posts delve into specific details like week 2 outcomes and mention how these therapies improve patient satisfaction, reflecting high interest and acknowledgment of their importance in dermatology.

AgreementModerate agreement

Most comments agree with the findings, highlighting the rapid effects of certain biologics like ixekizumab and brodalumab.

InterestHigh interest

Discussions show high interest, with posts emphasizing treatment speed and benefits, signaling engagement with the topic.

EngagementModerate engagement

Posts reference specific results, such as week 2 responses, indicating thoughtful engagement and deeper understanding.

ImpactHigh impact

The overall tone suggests acknowledgment of significant advancements in psoriasis treatment, implying high perceived impact.

Abstract in brief

  • This study compares the speed of effectiveness of 11 biologic treatments for moderate-to-severe psoriasis over the first 12 weeks, using advanced statistical methods (Bayesian and Frequentist network meta-analyses).
  • The results show that brodalumab and ixekizumab produce the fastest and most significant improvements in skin symptoms (PASI scores) and quality of life (DLQI) at various time points, particularly at weeks 2, 4, 8, and 12.
  • Overall, ixekizumab and brodalumab stand out for providing quick and effective relief in psoriasis, which is important for patient satisfaction and treatment decisions.]

Top posts

Most liked on X and Bluesky
Arvind Canchi (Conjeevaram)
@arvindcanchi · X

Ixekizumab and brodalumab provide the most rapid response and earliest clinical benefit in Rx of Psoriasis at week 2 among the biologics. Have a renal TX pt with Psoriasis. No data in that group I guess @silvishah @raja_1980 @BhushanSree @SreejithDr https://t.co/FsvMx1e06L

Dec 8, 2019 · 12 likes · 2 shares · 10,909 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @AdisJournals: Watch our latest video abstract accompanying a @DermatolTher meta-analysis! This short video is a great intro to the art…

Nov 17, 2020 · 1 share · 6,709 followers View post →
Krithika Mohan
@krithicism · X

RT @arvindcanchi: Ixekizumab and brodalumab provide the most rapid response and earliest clinical benefit in Rx of Psoriasis at week 2 amon…

Dec 9, 2019 · 2 shares · 2,741 followers View post →
Dermatology and Therapy
@DermatolTher · X

Biologic therapies have transformed the treatment of moderate-to-severe #psoriasis and have markedly improved multiple #patient outcomes. This article: https://t.co/TYZhQldwYx investigates the rapid response of biologic treatments for moderate-to severe plaque #psoriasis https://t.co/GnSsS60Y0T

Nov 6, 2019 · 1 share · 2,074 followers View post →
Anace Pastor ✨️ Renalis
@anace710 · X

RT @arvindcanchi: Ixekizumab and brodalumab provide the most rapid response and earliest clinical benefit in Rx of Psoriasis at week 2 amon…

Dec 9, 2019 · 2 shares · 1,899 followers View post →
AdisJournals
@AdisJournals · X

Watch our latest video abstract accompanying a @DermatolTher meta-analysis! This short video is a great intro to the article: https://t.co/yd6DxBEYrI #psoriasis #biologics #dermatology https://t.co/ro79Y53OkH

Nov 17, 2020 · 1 share · 579 followers View post →

All mentions

SystematicReviewBot
@EvidenceRobot · X

RT @AdisJournals: Watch our latest video abstract accompanying a @DermatolTher meta-analysis! This short video is a great intro to the art…

Nov 17, 2020 · 1 share · 6,709 followers View post →
AdisJournals
@AdisJournals · X

Watch our latest video abstract accompanying a @DermatolTher meta-analysis! This short video is a great intro to the article: https://t.co/yd6DxBEYrI #psoriasis #biologics #dermatology https://t.co/ro79Y53OkH

Nov 17, 2020 · 1 share · 579 followers View post →
Krithika Mohan
@krithicism · X

RT @arvindcanchi: Ixekizumab and brodalumab provide the most rapid response and earliest clinical benefit in Rx of Psoriasis at week 2 amon…

Dec 9, 2019 · 2 shares · 2,741 followers View post →
Anace Pastor ✨️ Renalis
@anace710 · X

RT @arvindcanchi: Ixekizumab and brodalumab provide the most rapid response and earliest clinical benefit in Rx of Psoriasis at week 2 amon…

Dec 9, 2019 · 2 shares · 1,899 followers View post →
Arvind Canchi (Conjeevaram)
@arvindcanchi · X

Ixekizumab and brodalumab provide the most rapid response and earliest clinical benefit in Rx of Psoriasis at week 2 among the biologics. Have a renal TX pt with Psoriasis. No data in that group I guess @silvishah @raja_1980 @BhushanSree @SreejithDr https://t.co/FsvMx1e06L

Dec 8, 2019 · 12 likes · 2 shares · 10,909 followers View post →
PremiumDermato
@premiumdermato · X

RT @DermatolTher: Biologic therapies have transformed the treatment of moderate-to-severe #psoriasis and have markedly improved multiple #p…

Nov 6, 2019 · 1 share · 218 followers View post →
Dermatology and Therapy
@DermatolTher · X

Biologic therapies have transformed the treatment of moderate-to-severe #psoriasis and have markedly improved multiple #patient outcomes. This article: https://t.co/TYZhQldwYx investigates the rapid response of biologic treatments for moderate-to severe plaque #psoriasis https://t.co/GnSsS60Y0T

Nov 6, 2019 · 1 share · 2,074 followers View post →