Adv Ther January 2020 PMID 31705437

Ibuprofen Safety at the Golden Anniversary: Are all NSAIDs the Same? A Narrative Review.

Giustino Varrassi, Joseph V Pergolizzi, Pascal Dowling, Antonella Paladini

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Mentions

88
Peak: 13 in May 2024
across 6 sources since Nov 2019

Extended reach

290,866
potential audience

Total likes

1,591

Video views

57,323

Mentions per month

Nov 2019 – Sep 2025

Where it's discussed

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AI synopsis

What people are saying

Discussion emphasizes the long-standing safety profile of ibuprofen, with posts referencing recent reviews and regulatory changes, such as the French pharmacies removing it from shelves. The tone varies from factual to cautious, with some users debating drug safety and others expressing interest in the research, illustrating a moderate level of engagement.

AgreementModerate agreement

Most discussions acknowledge the review's insights, with some emphasizing the safety profile of ibuprofen and its significance over 50 years.

InterestHigh interest

The topic generates high interest, especially with mentions of recent publications, reviews, and debates about NSAID safety, indicating active curiosity.

EngagementModerate engagement

Postings include references to specific research, discussions about safety issues, and calls for further information, showing moderate depth of engagement.

ImpactNeutral impact

While some posts highlight the importance of the review and recent regulatory actions, overall influence on public health or policy remains limited, reflected in neutral impact scores.

Abstract in brief

  • Ibuprofen has been widely used for over 50 years and remains a common over-the-counter pain relief option, with its safety profile being well-studied through clinical trials and real-world data.
  • While generally safe, ibuprofen can cause gastrointestinal issues, and its risks for heart, kidney, and liver problems depend on factors like dose and patient health, with some evidence of complex interactions with infections and potential endocrine disruption.
  • Despite some concerns, ibuprofen is considered effective for many types of pain with a relatively favorable safety profile, though ongoing research continues to uncover its unique effects and risks compared to other NSAIDs.

Top posts

Most liked on X and Bluesky
Keith Siau
@drkeithsiau · X

@Scott_M23 Or striking the balance between COX-1 vs COX-2 inhibition https://t.co/xuTVa5Ad8S https://t.co/fYExobFdvk

Sep 2, 2023 · 7 likes · 1 share · 201,875 followers View post →
Marc Bevand
@zorinaq · X

@jesterchen42 @tagesschau @BMG_Bund @MedUni_Wien Results of the ANSM study were recently published in international medical literature. For example: https://t.co/uOpwPdhErC (November 2019) Because of the findings, French pharmacies were required to remove ibuprofen from the shelves in Jan 2020. It's now "behind the counter"

Mar 15, 2020 · 5 likes · 7,932 followers View post →
Álvaro
@Alvaroomega19 · X

@RaulMiralles4 @GPlandemiun @salud71385 @piter_vries @Mentor1Universa @DanielEcidi @amvtw @Loreno50077 @CapitaneaJose @DeMogollones @Manolotabaiba1 @PComentator @CafeyGrafeno @irma_vg @aliciacgviolin @BartEjea @MemnochAngel @jon_tr1ste @romsanra @putasycocas @84DiegoQM @Luis13104072 @No_se_alquila @Jorge06266221 @CarlosVecino4 @Paula13vega @Hondontown @miacat47 @BorregoUnadeca @LeilaYLab @sirkioso @ashgam666 @jesus_colega_ @Mirambella @SdeSanty @LekLaial @ElRecogelatas @Anorcr1 @AI2BO4 @toobaffled Medicamentos como este? No veo que el Ibuprofeno se haya retirado por eso

May 21, 2024 · 3 likes · 1 share · 1,114 followers View post →
Álvaro
@Alvaroomega19 · X

@dinamo1234 @PedroGrela @DeMogollones @Hondoncity @Manolotabaiba1 Toma, malabares. Ya te dije que un payaso como tú solo engañaba a los cuatro personajes que te dan la razón

May 3, 2024 · 2 likes · 1 share · 1,114 followers View post →
Antonio Lewis, MD
@AntonioLewisMD · X

NSAIDs are the most widely used OTC drugs ever (besides acetaminophen). Every physician should be an expert. Varrassi, G., Pergolizzi, J.V., Dowling, P. et al. Ibuprofen Safety at the Golden Anniversary: Are all NSAIDs the Same? A Narrative Review. Adv Ther (2020) #foamed https://t.co/V4MCpnki5U

May 15, 2020 · 2 likes · 661 followers View post →
omphaloskepsis
@fammi_ridere · X

@Metallbiker1 @Alvaroomega19 @bohemi4nCabo @Farmaenfurecida El Ibuprofeno puede tener efectos secundarios tan serios como la vacuna, incluso problemas cardiovasculares https://t.co/Em38fDWGSt

Apr 10, 2024 · 1 like · 1,262 followers View post →

All mentions

Ibuprofen and Kidney Damage Risks in Long-Term Use

Ibuprofen has been widely used for over 50 years and remains a common over-the-counter pain relief option, with its safety profile being well-studied through clinical trials and real-world data. This video explores the…

DIAB-HEALTH · May 20, 2024 686 views
Manolo Tabaiba
@Manolotabaiba1 · X

RT @Alvaroomega19: @RaulMiralles4 @GPlandemiun @salud71385 @piter_vries @Mentor1Universa @DanielEcidi @amvtw @Loreno50077 @CapitaneaJose @D…

May 22, 2024 · 1 share · 830 followers View post →
Álvaro
@Alvaroomega19 · X

@RaulMiralles4 @GPlandemiun @salud71385 @piter_vries @Mentor1Universa @DanielEcidi @amvtw @Loreno50077 @CapitaneaJose @DeMogollones @Manolotabaiba1 @PComentator @CafeyGrafeno @irma_vg @aliciacgviolin @BartEjea @MemnochAngel @jon_tr1ste @romsanra @putasycocas @84DiegoQM @Luis13104072 @No_se_alquila @Jorge06266221 @CarlosVecino4 @Paula13vega @Hondontown @miacat47 @BorregoUnadeca @LeilaYLab @sirkioso @ashgam666 @jesus_colega_ @Mirambella @SdeSanty @LekLaial @ElRecogelatas @Anorcr1 @AI2BO4 @toobaffled Medicamentos como este? No veo que el Ibuprofeno se haya retirado por eso

May 21, 2024 · 3 likes · 1 share · 1,114 followers View post →
Manolo Tabaiba
@Manolotabaiba1 · X

RT @Alvaroomega19: @dinamo1234 @PedroGrela @DeMogollones @Hondoncity @Manolotabaiba1 Toma, malabares. Ya te dije que un payaso como tú solo…

May 4, 2024 · 1 share · 830 followers View post →
Álvaro
@Alvaroomega19 · X

@dinamo1234 @PedroGrela @DeMogollones @Hondoncity @Manolotabaiba1 Toma, malabares. Ya te dije que un payaso como tú solo engañaba a los cuatro personajes que te dan la razón

May 3, 2024 · 2 likes · 1 share · 1,114 followers View post →
Álvaro
@Alvaroomega19 · X

@Aquilin84000846 @MariolySosaP Tampoco tome ningún medicamento entonces, siguiendo esa lógica. https://t.co/jHFbSNKbsk

May 2, 2024 · 1,114 followers View post →
omphaloskepsis
@fammi_ridere · X

@Metallbiker1 @Alvaroomega19 @bohemi4nCabo @Farmaenfurecida El Ibuprofeno puede tener efectos secundarios tan serios como la vacuna, incluso problemas cardiovasculares https://t.co/Em38fDWGSt

Apr 10, 2024 · 1 like · 1,262 followers View post →
Thomas F. Varley
@ThosVarley · X

@7Jugo @PaulAustin3w Dude, that's not how this works. You can't claim "my drug is safer than all other drugs" and then when someone says "is it as safe as this drug that the FDA allows to be sold OTC", turn around and say "no u." But try this on for size: https://t.co/UJpy3a7pJB

Feb 26, 2024 · 4,667 followers View post →
Le Mat
@_Settia_ · X

RT @drkeithsiau: @Scott_M23 Or striking the balance between COX-1 vs COX-2 inhibition https://t.co/xuTVa5Ad8S https://t.co/fYExobFdvk

Sep 2, 2023 · 1 share · 342 followers View post →
Keith Siau
@drkeithsiau · X

@Scott_M23 Or striking the balance between COX-1 vs COX-2 inhibition https://t.co/xuTVa5Ad8S https://t.co/fYExobFdvk

Sep 2, 2023 · 7 likes · 1 share · 201,875 followers View post →
Alejandro Vargas
@AVargas7759 · X

Muy buena revisión sobre AINES https://t.co/QnHectrh11 https://t.co/kP5rce3woi

Jun 5, 2020 · 626 followers View post →
Antonio Lewis, MD
@AntonioLewisMD · X

NSAIDs are the most widely used OTC drugs ever (besides acetaminophen). Every physician should be an expert. Varrassi, G., Pergolizzi, J.V., Dowling, P. et al. Ibuprofen Safety at the Golden Anniversary: Are all NSAIDs the Same? A Narrative Review. Adv Ther (2020) #foamed https://t.co/V4MCpnki5U

May 15, 2020 · 2 likes · 661 followers View post →
Marc Bevand
@zorinaq · X

@jesterchen42 @tagesschau @BMG_Bund @MedUni_Wien Results of the ANSM study were recently published in international medical literature. For example: https://t.co/uOpwPdhErC (November 2019) Because of the findings, French pharmacies were required to remove ibuprofen from the shelves in Jan 2020. It's now "behind the counter"

Mar 15, 2020 · 5 likes · 7,932 followers View post →
Catherina
@justthevax · X

@theclaudbarr1 @HildegardP @mikew4EU @Adam_SH69 why is there no mention of this in this recent review? https://t.co/K1JzBs48CC

Mar 14, 2020 · 4,668 followers View post →
giuvarr
@giuvarr · X

Here is the link, in case you would have copy of the paper - https://t.co/NsBH6QS7CV https://t.co/cvnz5w0Z6f

Nov 13, 2019 · 1,471 followers View post →
Anestesistas & Anestesiologistas
@AnestesistasA · X

https://t.co/9beps8fLCx https://t.co/TFM9HMa8DC

Nov 12, 2019 · 263 followers View post →
giuvarr
@giuvarr · X

Springer has just published on @AdvancesTherapy an interesting review on #ibuprofen, in the occasion of the golden anniversary of the drug - https://t.co/NsBH6QS7CV

Nov 12, 2019 · 1,471 followers View post →
Advances in Therapy
@AdvancesTherapy · X

Read our latest narrative review authored by the Anesthesia and Pain Section Editor of Advances in Therapy @giuvarr - #Ibuprofen Safety at the Golden Anniversary: Are all #NSAIDs the Same? https://t.co/uHam3dzIrx https://t.co/KSfascaEj6

Nov 11, 2019 · 1,192 followers View post →
giuvarr
@giuvarr · X

Just appeared on line, the golden anniversary of ibuprofen and its safety profile - https://t.co/5sBpm6n9lV

Nov 10, 2019 · 1,471 followers View post →
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