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Adv Sci (Weinh) November 2019 PMID 31763151

Janus Nanobullets Combine Photodynamic Therapy and Magnetic Hyperthermia to Potentiate Synergetic Anti-Metastatic Immunotherapy.

Zheng Wang, Fan Zhang, Dan Shao, Zhimin Chang, Lei Wang, Hanze Hu, Xiao Zheng, Xuezhao Li, Fangman Chen, Zhaoxu Tu, Mingqiang Li, Wen Sun, Li Chen, Wen-Fei Dong

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Mentions

8
Peak: 3 in Sep 2019
across 2 sources since Sep 2019

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Sep 2019 – Sep 2023

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AI synopsis

What people are saying

The comments reflect a mostly favorable perspective toward the publication, with phrases like 'potentiate synergetic therapy' and 'innovative particles,' indicating excitement and recognition of breakthrough potential. The tone highlights its promising approach in targeted cancer treatment, driving interest and engagement among readers attuned to emerging medical technologies.

AgreementModerate agreement

Most discussions express positive support or acknowledgment of the research's potential, indicating general agreement with its significance.

InterestHigh interest

The discussions demonstrate strong curiosity about the innovative combination of therapies and the potential benefits for cancer treatment.

EngagementModerate engagement

Participants refer to specific aspects like photodynamic therapy, magnetic hyperthermia, and immune responses, showing active engagement.

ImpactModerate impact

There is a shared view that this research could be transformational in cancer therapy, suggesting a moderate recognition of its potential influence.

Abstract in brief

  • Janus nanobullets are innovative particles that combine photodynamic therapy (PDT) and magnetic hyperthermia to enhance anti-metastatic immunotherapy, targeting both primary tumors and distant metastases effectively.
  • These nanoparticles consist of chlorine e6 (Ce6) loaded within mesoporous silica bodies and magnetic heads, designed for tumor targeting, controlled drug release triggered by redox and pH conditions, and prolonged circulation, especially when cloaked with cancer cell membranes.
  • When used together with an anti-CTLA4 antibody, these nanobullets induce immunogenic cell death, leading to strong, tumor-specific immune responses that can eradicate both primary and metastatic tumors with minimal side effects.]
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Advanced Portfolio News
@AdvPortfolio · X

Anti‐metastatic immunotherapy with Janus nanobullets. Read more on this approach of combining #photodynamic therapy and #magnetic hyperthermia in https://t.co/TtMkDp8LWQ https://t.co/dWOYtNfQDM

Sep 13, 2019 · 8 likes · 5 shares · 34,868 followers View post →
EurekaMag
@EurekaMag · X

Janus Nanobullets Combine Photodynamic Therapy and Magnetic Hyperthermia to Potentiate Synergetic Anti-Metastatic Immunotherapy https://t.co/Bz29CcPBY9

Nov 13, 2020 · 3 shares · 6,529 followers View post →
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@POPLINE_org · X

RT @EurekaMag: Janus Nanobullets Combine Photodynamic Therapy and Magnetic Hyperthermia to Potentiate Synergetic Anti-Metastatic Immunother…

Nov 13, 2020 · 3 shares · 5,184 followers View post →
CRS NANO
@CRS_FG_NANO · X

RT @AdvSciNews: Anti‐metastatic immunotherapy with Janus nanobullets. Read more on this approach of combining #photodynamic therapy and #m…

Sep 13, 2019 · 5 shares · 3,039 followers View post →
Science Alerts
@Science_Alerts · X

RT @EurekaMag: Janus Nanobullets Combine Photodynamic Therapy and Magnetic Hyperthermia to Potentiate Synergetic Anti-Metastatic Immunother…

Nov 13, 2020 · 3 shares · 1,214 followers View post →
Arnab Halder
@arnabkemi · X

RT @AdvSciNews: Anti‐metastatic immunotherapy with Janus nanobullets. Read more on this approach of combining #photodynamic therapy and #m…

Sep 13, 2019 · 5 shares · 763 followers View post →

All mentions

Science Alerts
@Science_Alerts · X

RT @EurekaMag: Janus Nanobullets Combine Photodynamic Therapy and Magnetic Hyperthermia to Potentiate Synergetic Anti-Metastatic Immunother…

Nov 13, 2020 · 3 shares · 1,214 followers View post →
POPLINE
@POPLINE_org · X

RT @EurekaMag: Janus Nanobullets Combine Photodynamic Therapy and Magnetic Hyperthermia to Potentiate Synergetic Anti-Metastatic Immunother…

Nov 13, 2020 · 3 shares · 5,184 followers View post →
EurekaMag
@EurekaMag · X

Janus Nanobullets Combine Photodynamic Therapy and Magnetic Hyperthermia to Potentiate Synergetic Anti-Metastatic Immunotherapy https://t.co/Bz29CcPBY9

Nov 13, 2020 · 3 shares · 6,529 followers View post →
ImmunotherapyPapers
@Immunotx_papers · X

Janus Nanobullets Combine Photodynamic Therapy and Magnetic Hyperthermia to Potentiate Synergetic Anti-Metastatic Immunotherapy. https://t.co/ctjgy8wGrA

Nov 26, 2019 · 247 followers View post →
Arnab Halder
@arnabkemi · X

RT @AdvSciNews: Anti‐metastatic immunotherapy with Janus nanobullets. Read more on this approach of combining #photodynamic therapy and #m…

Sep 13, 2019 · 5 shares · 763 followers View post →
CRS NANO
@CRS_FG_NANO · X

RT @AdvSciNews: Anti‐metastatic immunotherapy with Janus nanobullets. Read more on this approach of combining #photodynamic therapy and #m…

Sep 13, 2019 · 5 shares · 3,039 followers View post →
Advanced Portfolio News
@AdvPortfolio · X

Anti‐metastatic immunotherapy with Janus nanobullets. Read more on this approach of combining #photodynamic therapy and #magnetic hyperthermia in https://t.co/TtMkDp8LWQ https://t.co/dWOYtNfQDM

Sep 13, 2019 · 8 likes · 5 shares · 34,868 followers View post →