March 2020 PMID 31813108

Influence of a Combined Gluten-Free and Casein-Free Diet on Behavior Disorders in Children and Adolescents Diagnosed with Autism Spectrum Disorder: A 12-Month Follow-Up Clinical Trial.

Pablo José González-Domenech, Francisco Díaz Atienza, Carlos García Pablos, María Luisa Fernández Soto, José María Martínez-Ortega, Luis Gutiérrez-Rojas

Mentions

90
Peak: 69 in Dec 2019
across 6 sources since Dec 2019

Extended reach

300,210
potential audience

Total likes

187

Video views

1,142

Mentions per month

Dec 2019 – Sep 2025

Where it's discussed

  • X / Twitter80 posts
  • News4 articles
  • YouTube2 videos
  • Blogs2 articles
  • Facebook1 posts
  • Instagram1 posts

AI synopsis

What people are saying

The discussions primarily support the conclusion that gluten-free and casein-free diets do not significantly modify behavior in autistic children, with phrases like 'no benefit' and 'no significant changes' indicating strong agreement. Some discussions question the significance, mentioning the study's call for better respondent identification, which shows moderate engagement and curiosity about nuances, supported by words like 'inconclusive' and 'further research needed.'

AgreementStrong agreement

Most discussions highlight the study's conclusion that GFCF diets do not lead to behavioral improvements in children with autism, showing strong consensus.

InterestModerate interest

While many posts focus on confirming the study's findings, some express curiosity about the nuances and the need for further research.

EngagementModerate engagement

Posts generally reference the research's methodology and results, indicating moderate engagement, especially with citation of the clinical trial.

ImpactModerate impact

The discussions emphasize that the findings are likely to influence dietary recommendations and future research directions in autism treatment.

Abstract in brief

  • The study investigated the impact of a gluten-free and casein-free (GFCF) diet on behavior in children with Autism Spectrum Disorder (ASD) over a 12-month period.
  • Participants followed both a normal diet and a GFCF diet in a crossover trial, with behavior and urinary beta-casomorphin levels assessed at multiple points.
  • Results indicated no significant changes in behavior or urinary beta-casomorphin concentrations linked to the GFCF diet, suggesting further research with more rigorous methods is necessary.

Top posts

Most liked on X and Bluesky
Timothy Caulfield
@CaulfieldTim · X

Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of autism" https://t.co/0Hgv1ATpiN cc @AgainstCures @A4AOntario

Dec 21, 2019 · 59 likes · 30 shares · 88,310 followers View post →
José Ignacio Leyda
@ignacioleyda · X

Dec 10, 2019 · 52 likes · 31 shares · 8,263 followers View post →
Pablo Richly
@PabloRichly · X

Las dietas libres de gluten y caseína no reportarían ningún beneficio conductual en autismo.https://t.co/KbhR9FWM51

Dec 22, 2019 · 13 likes · 5 shares · 6,723 followers View post →
Douglas Kalman PhD
@dougkalmanphdrd · X

Can diet affect autism? New research says no benefit of eating gluten or casein free diets - behavior unchanged. https://t.co/9bb3qhY6Zd

Dec 24, 2019 · 10 likes · 2 shares · 5,458 followers View post →
Spectrum (Autism Research News)
@Spectrum · X

A gluten- and casein-free diet did not affect autistic children’s behaviors in a small clinical trial (via @springerpsych) #SpectrumSpotted https://t.co/vHgIGmhTz9

Dec 18, 2019 · 8 likes · 3 shares · 30,857 followers View post →
ひろあ@みんなの受験アドバイザー
@hiroa11011 · X

グルテンフリーとカゼインフリーは自閉症の改善とは関係が見られないという研究。 https://t.co/lCtUbIiLbW

Jul 11, 2020 · 2 likes · 1 share · 2,122 followers View post →

All mentions

とも@グルテンフリー情報発信
@gulten_free_rst · X

グルテンとカゼインを抜く食事(GFCF)が自閉症の子どもたちに与える影響を調べたけど、行動に大きな変化は見られなかったんだ。尿中のβカソモルフィン濃度とも関係がなかったみたい。もっと長期間の研究が必要だね。グルテンフリーを実践している人も、あまり気負わずにね。 https://t.co/OUpSEkZOlI

Sep 29, 2025 · 29 followers View post →
ひろあ@みんなの受験アドバイザー
@hiroa11011 · X

こちらはグルテンフリーなどに優位差が見られないとする研究。 https://t.co/lCtUbIAUq4

Dec 24, 2023 · 1 like · 2,122 followers View post →
ひろあ@みんなの受験アドバイザー
@hiroa11011 · X

で、こっちは有意の差はないってものです。グルテンとカゼインはよくわからないですね。 https://t.co/lCtUbIAUq4

Jan 3, 2023 · 1 like · 2,122 followers View post →
Dr. PNW Ex-pat (she/her)
@katie_harmoney · X

3) She also mentions that her son eats a gluten free diet, which apparently improves his behaviors. Although this is intriguing and is an area of investigation, the data is inconclusive at best. https://t.co/qMy1lKAhKe 6/8

Jan 25, 2021 · 778 followers View post →
Phoebe ✌
@Pheebs_9876 · X

@Visual_Artefact Psst... hey PETA... No-one fucking cares what bigoted bullshit you spout anymore. Here's a systematic review of the research from 2018 and a longitudinal study from 2020, and guess what: Nothing. They found jack shit. Get fucked https://t.co/15urUgudyx https://t.co/QWXTgBJ2Ne

Jan 5, 2021 · 2 likes · 962 followers View post →
ひろあ@みんなの受験アドバイザー
@hiroa11011 · X

グルフリとカゼインフリーの否定的な研究。 https://t.co/lCtUbIiLbW

Oct 25, 2020 · 1 like · 2,122 followers View post →
ひろあ@みんなの受験アドバイザー
@hiroa11011 · X

グルテンフリーとカゼインフリーは自閉症の改善とは関係が見られないという研究。 https://t.co/lCtUbIiLbW

Jul 11, 2020 · 2 likes · 1 share · 2,122 followers View post →
Kelly L. Coburn (they/them)
@KCoburnSLP · X

"No significant behavioral changes and no association with urinary beta-casomorphin concentrations were found after GFCF diet. A 6-month GFCF diet do not induce significant changes in behavioral symptoms of autism..." https://t.co/5xW6uAjrX2

Feb 16, 2020 · 1 like · 572 followers View post →
وليد عبدالكريم علي
@albelushiwalid · X

RT @Autism_Journal: Influence of a Combined Gluten-Free and Casein-Free Diet on Behavior Disorders in Children and Adolescents Diagnosed wi…

Feb 10, 2020 · 1 share · 840 followers View post →
#Autism
@Autism_Journal · X

Influence of a Combined Gluten-Free and Casein-Free Diet on Behavior Disorders in Children and Adolescents Diagnosed with Autism Spectrum Disorder: A 12-Month Follow-Up Clinical Trial https://t.co/bhJmR2FHm3 #Springer #JournalofAutismandDevelopmentalDisorders

Feb 10, 2020 · 1 share · 388 followers View post →
Medipedi
@Medipedinet · X

Otistik spektrum bozukluğu olan çocuklarda glutensiz ve kazeinsiz beslenme, davranış semptomlarımda tedavi sağlamadı. Kaynak makale: https://t.co/81iOyntVk4

Feb 6, 2020 · 1 like · 263 followers View post →
Andrew Morris
@andrewmorrisuk · X

RT @Griffin_OT: This article on gluten and casein free diets for children with hashtag #asd concludes: "No significant behavioral changes a…

Dec 31, 2019 · 2 shares · 15,370 followers View post →
Kim Griffin
@Griffin_OT · X

RT @Griffin_OT: This article on gluten and casein free diets for children with hashtag #asd concludes: "No significant behavioral changes a…

Dec 31, 2019 · 2 shares · 10,009 followers View post →
Janice Baker
@JaniceBakerRD · X

RT @dougkalmanphdrd: Can diet affect autism? New research says no benefit of eating gluten or casein free diets - behavior unchanged. https…

Dec 24, 2019 · 2 shares · 3,535 followers View post →
Raul
@RaulM06 · X

RT @dougkalmanphdrd: Can diet affect autism? New research says no benefit of eating gluten or casein free diets - behavior unchanged. https…

Dec 24, 2019 · 2 shares · 847 followers View post →
Douglas Kalman PhD
@dougkalmanphdrd · X

Can diet affect autism? New research says no benefit of eating gluten or casein free diets - behavior unchanged. https://t.co/9bb3qhY6Zd

Dec 24, 2019 · 10 likes · 2 shares · 5,458 followers View post →
John Pernik
@JohnPernik · X

RT @PabloRichly: Las dietas libres de gluten y caseína no reportarían ningún beneficio conductual en autismo.https://t.co/KbhR9FWM51

Dec 22, 2019 · 5 shares · 369 followers View post →
FriendsOfSciMed
@FriendsOfSciMed · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 22, 2019 · 30 shares · 2,683 followers View post →
Terry Polevoy, MD
@TerryPolevoy · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 22, 2019 · 30 shares · 1,702 followers View post →
Dra. Iris Luna
@irislunaoficial · X

RT @PabloRichly: Las dietas libres de gluten y caseína no reportarían ningún beneficio conductual en autismo.https://t.co/KbhR9FWM51

Dec 22, 2019 · 5 shares · 1,985 followers View post →
Paul D'Hondt
@pauldhondt · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 22, 2019 · 30 shares · 741 followers View post →
La que manda a freír mondongo
@NikischCarolina · X

RT @PabloRichly: Las dietas libres de gluten y caseína no reportarían ningún beneficio conductual en autismo.https://t.co/KbhR9FWM51

Dec 22, 2019 · 5 shares · 2,905 followers View post →
Lunera
@Lunera_Luz · X

RT @PabloRichly: Las dietas libres de gluten y caseína no reportarían ningún beneficio conductual en autismo.https://t.co/KbhR9FWM51

Dec 22, 2019 · 5 shares · 2,681 followers View post →
Pablo Richly
@PabloRichly · X

Las dietas libres de gluten y caseína no reportarían ningún beneficio conductual en autismo.https://t.co/KbhR9FWM51

Dec 22, 2019 · 13 likes · 5 shares · 6,723 followers View post →
Simon Bacon
@sbacon20 · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 22, 2019 · 30 shares · 657 followers View post →
Lamorna Nutrition & Fitness
@_Lamorna · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 22, 2019 · 30 shares · 412 followers View post →
ꙮMantis Space Marine
@emccoy_writer · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 22, 2019 · 30 shares · 1,108 followers View post →
spite is my (fully vaccinated)motivation
@1EEX303 · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 22, 2019 · 30 shares · 111 followers View post →
Brett Chrest
@Chrest_brett · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 21, 2019 · 30 shares · 1,532 followers View post →
golemgirlgoop.bsky.social
@ayellowbirds · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 21, 2019 · 30 shares · 259 followers View post →
Bill Peters
@BillPeters30 · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 21, 2019 · 30 shares · 973 followers View post →
Bri Adamson
@bri_adamson · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 21, 2019 · 30 shares · 123 followers View post →
Alan Levinovitz
@AlanLevinovitz · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 21, 2019 · 30 shares · 24,074 followers View post →
ianfmusgrave
@ianfmusgrave · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 21, 2019 · 30 shares · 2,712 followers View post →
Prof Emily Gard Marshall (she/her)
@DrEmilyMarshall · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 21, 2019 · 30 shares · 1,677 followers View post →
Denise Dickeson
@MootildaD · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 21, 2019 · 30 shares · 408 followers View post →
LILLY
@LillyPaddd12 · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 21, 2019 · 30 shares · 214 followers View post →
Triske to Exile
@TriskeMTG · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 21, 2019 · 30 shares · 1,531 followers View post →
Therapeutics Initiative
@Drug_Evidence · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 21, 2019 · 30 shares · 7,017 followers View post →
Dr. Rita McCracken, MD, PhD (she/her)
@DrRitaMc · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 21, 2019 · 30 shares · 5,378 followers View post →
John Hulleman
@jrhulleman · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 21, 2019 · 30 shares · 354 followers View post →
damnselfly on tumblr and bsky
@damnse1fly · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 21, 2019 · 30 shares · 1,185 followers View post →
John Muir @johnmuir@aus.social
@johnamuir · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 21, 2019 · 30 shares · 1,187 followers View post →
Debunking Denialism
@debunkdenialism · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 21, 2019 · 30 shares · 5,458 followers View post →
Dr. Philippe Chouinard
@DrPChouinard · X

RT @CaulfieldTim: Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of aut…

Dec 21, 2019 · 30 shares · 3,316 followers View post →
Timothy Caulfield
@CaulfieldTim · X

Study: "A 6-month GFCF [#glutenfree and #caseinfree] diet do not induce significant changes in behavioral symptoms of autism" https://t.co/0Hgv1ATpiN cc @AgainstCures @A4AOntario

Dec 21, 2019 · 59 likes · 30 shares · 88,310 followers View post →
Gedanken Karrussel
@Denkkarrussel · X

RT @Spectrum: A gluten- and casein-free diet did not affect autistic children’s behaviors in a small clinical trial (via @springerpsych) #S…

Dec 19, 2019 · 3 shares · 1,208 followers View post →
Spectrum (Autism Research News)
@Spectrum · X

A gluten- and casein-free diet did not affect autistic children’s behaviors in a small clinical trial (via @springerpsych) #SpectrumSpotted https://t.co/vHgIGmhTz9

Dec 18, 2019 · 8 likes · 3 shares · 30,857 followers View post →
AnaPau
@anapau80 · X

RT @ignacioleyda:

Dec 16, 2019 · 31 shares · 249 followers View post →
Sol
@soldeloza · X

RT @ignacioleyda:

Dec 15, 2019 · 31 shares · 327 followers View post →
Maria Belen Gonzalez
@MariaBe68061225 · X

RT @ignacioleyda:

Dec 13, 2019 · 31 shares · 533 followers View post →
Rafa ARANA
@arana_rab · X

RT @ignacioleyda:

Dec 12, 2019 · 31 shares · 522 followers View post →
Familias TDAH Ciudad de México
@TdahMexico · X

RT @ignacioleyda:

Dec 12, 2019 · 31 shares · 235 followers View post →
Javier López Ruiz
@Javilruiz · X

RT @ignacioleyda:

Dec 11, 2019 · 31 shares · 274 followers View post →
Susi Cordón. Directora d'Aprenem Autisme
@SusiCordon · X

RT @ignacioleyda:

Dec 11, 2019 · 31 shares · 201 followers View post →
Haydee Rodriguez
@haydeecossa · X

RT @ignacioleyda:

Dec 11, 2019 · 31 shares · 265 followers View post →
M. Mamajón
@MMamajon · X

RT @ignacioleyda:

Dec 11, 2019 · 31 shares · 1,650 followers View post →
Carmen Nieves Martínez Gil
@cnmartinezgil · X

RT @ignacioleyda:

Dec 11, 2019 · 31 shares · 251 followers View post →
Luz Margarita
@luzma_subjur · X

RT @ignacioleyda:

Dec 11, 2019 · 31 shares · 1,230 followers View post →
John H. Mallory
@Miklobius · X

RT @ignacioleyda:

Dec 11, 2019 · 31 shares · 530 followers View post →
Gonzalo Monedero
@GonzaloMonedero · X

RT @ignacioleyda:

Dec 11, 2019 · 31 shares · 2,858 followers View post →
Sabina Barrios-Fernandez
@OcupaTEA · X

RT @ignacioleyda:

Dec 11, 2019 · 31 shares · 7,492 followers View post →
Alejandro Solana
@Alesovig · X

RT @ignacioleyda:

Dec 11, 2019 · 31 shares · 370 followers View post →
Ignacio
@inime31 · X

RT @ignacioleyda:

Dec 11, 2019 · 31 shares · 34 followers View post →
Dr. Patch Ecco, MD
@eldoc24 · X

RT @ignacioleyda:

Dec 10, 2019 · 31 shares · 4,605 followers View post →
Maria Laura Cordero
@mlcorderov · X

RT @ignacioleyda:

Dec 10, 2019 · 31 shares · 1,012 followers View post →
Maria Laura Braz
@neuropediat · X

RT @ignacioleyda:

Dec 10, 2019 · 31 shares · 6,167 followers View post →
Anel Reeves
@anelinda30 · X

RT @ignacioleyda:

Dec 10, 2019 · 31 shares · 764 followers View post →
EskeleThor
@EskeleThor · X

RT @ignacioleyda:

Dec 10, 2019 · 31 shares · 404 followers View post →
Leonel Bobadilla B
@leobobadilla · X

RT @ignacioleyda:

Dec 10, 2019 · 31 shares · 1,446 followers View post →
María Azancot
@maazancot · X

RT @ignacioleyda:

Dec 10, 2019 · 31 shares · 1,002 followers View post →
Vanessookie
@vanessookie · X

RT @ignacioleyda:

Dec 10, 2019 · 31 shares · 119 followers View post →
Horacio Toraya
@HoracioToraya · X

RT @ignacioleyda:

Dec 10, 2019 · 31 shares · 593 followers View post →
Estela Alvarez
@Estelamatrona · X

RT @ignacioleyda:

Dec 10, 2019 · 31 shares · 93 followers View post →
Dinorah Castro
@Dinorah_Castro · X

RT @ignacioleyda:

Dec 10, 2019 · 31 shares · 727 followers View post →
José Ignacio Leyda
@ignacioleyda · X

Dec 10, 2019 · 52 likes · 31 shares · 8,263 followers View post →
#Autism
@Autism_Journal · X

Influence of a Combined Gluten-Free and Casein-Free Diet on Behavior Disorders in Children and Adolescents Diagnosed with Autism Spectrum Disorder: A 12-Month Follow-Up Clinical Trial. https://t.co/uGcTBWgrFb #PubMed #Autism

Dec 10, 2019 · 388 followers View post →
Paul Whiteley
@PaulWhiteleyPhD · X

Influence of a Combined Gluten-Free and Casein-Free Diet on Behavior Disorders in Children and Adolescents Diagnosed With Autism Spectrum Disorder https://t.co/OOwkFaBdMt No effects. But: "..needed to identify better those respondents to GFCF diets". Mmm: https://t.co/FHyEkbnIOt

Dec 10, 2019 · 1 like · 4,993 followers View post →
#Autism
@Autism_Journal · X

Influence of a Combined Gluten-Free and Casein-Free Diet on Behavior Disorders in Children and Adolescents Diagnosed with Autism Spectrum Disorder: A 12-Month Follow-Up Clinical Trial https://t.co/bhJmR2FHm3 #Springer #JournalofAutismandDevelopmentalDisorders

Dec 8, 2019 · 388 followers View post →
yasu
@yasufurosan · X

グルテンとカゼインフリー食でASDの症状改善せず。 Influence of a Combined Gluten-Free and Casein-Free Diet on Behavior Disorders in Children and Adolescents Diagnosed with Autism Spectrum Disorder: A 12-Month Follow-Up Clinical Trial https://t.co/7p05jEAZeI #05_autismjournals

Dec 7, 2019 · 1 like · 291 followers View post →
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