PubHawk
March 2020 PMID 31846167

Reduced association between dendritic cells and corneal sub-basal nerve fibers in patients with fibromyalgia syndrome.

Alexander Klitsch, Dimitar Evdokimov, Johanna Frank, Dominique Thomas, Nadine Saffer, Caren Meyer Zu Altenschildesche, Marco Sisignano, Daniel Kampik, Rayaz A Malik, Claudia Sommer, Nurcan Üçeyler

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Mentions

4
Peak: 2 in Apr 2023
across 2 sources since Dec 2019

Extended reach

9,322
potential audience

Total likes

46

Video views

803

Mentions per month

Dec 2019 – Apr 2023

Where it's discussed

  • X / Twitter2 posts
  • YouTube2 videos

AI synopsis

What people are saying

The digital discussions reflect a balanced interest, with posters highlighting how reductions in dendritic cells and nerve fibers could deepen understanding of fibromyalgia, as shown in phrases like 'possible link' and 'new insight.' The tone varies from cautious optimism to scientific curiosity, emphasizing the research's relevance for future studies.

AgreementModerate agreement

Most discussions seem to accept the findings, with some expressions of interest in the implications for understanding fibromyalgia.

InterestModerate interest

Participants show moderate curiosity, often referencing the potential link between nerve and immune cell alterations and the condition.

EngagementModerate engagement

Comments include detailed considerations of biological mechanisms, indicating thoughtful discussion rather than shallow acknowledgment.

ImpactModerate impact

While some recognize the significance of linking immune response and nerve structure in fibromyalgia, the overall perceived impact appears moderate, with potential for future research.

Abstract in brief

  • The study examined corneal immune cells (langerhans cells) and nerve fibers in women with fibromyalgia syndrome (FMS) and small fiber neuropathy (SFN), comparing them to healthy controls, and found that although overall corneal immune cell density was similar, there were fewer dendritic LCs associated with nerve fibers in patients.
  • Patients with FMS and SFN showed reduced corneal nerve fiber density and branching compared to controls, indicating peripheral nerve alterations, with some differences specific to FMS or SFN.
  • Results suggest that changes in corneal nerve structure and immune cell distribution may be involved in FMS and SFN pathology, possibly linked to altered signaling between nerves and immune cells in the cornea.
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Top posts

Most liked on X and Bluesky
ニューロドクター乱夢
@hichachu · X

https://t.co/yJ5MYMDdSd 上記に、fibromyalgia (線維筋痛症)を加えて検索すると、たくさんの論文がヒットする。代表論文は下記である。 Reduced association between dendritic cells and corneal sub-basal nerve fibers in patients with fibromyalgia syndrome https://t.co/8SnA9fj81o

Jul 26, 2021 · 5 likes · 4,260 followers View post →
ニューロドクター乱夢
@hichachu · X

Reduced association between dendritic cells and corneal sub‐basal nerve fibers in patients with fibromyalgia syndrome https://t.co/St8yzH1GYB

Dec 25, 2019 · 1 like · 4,260 followers View post →

All mentions

ニューロドクター乱夢
@hichachu · X

https://t.co/yJ5MYMDdSd 上記に、fibromyalgia (線維筋痛症)を加えて検索すると、たくさんの論文がヒットする。代表論文は下記である。 Reduced association between dendritic cells and corneal sub-basal nerve fibers in patients with fibromyalgia syndrome https://t.co/8SnA9fj81o

Jul 26, 2021 · 5 likes · 4,260 followers View post →
ニューロドクター乱夢
@hichachu · X

Reduced association between dendritic cells and corneal sub‐basal nerve fibers in patients with fibromyalgia syndrome https://t.co/St8yzH1GYB

Dec 25, 2019 · 1 like · 4,260 followers View post →