https://t.co/Qg3U8U4RJw Potential caffeine downside Vitamin D receptor activation is needed to inhibit the NLRP3 inflammasome & caspase-1, a central inflammatory enzyme that activates interleukin cytokines Caffeine decreases vitamin D receptor expression https://t.co/fPE5R1y6l3
Vitamin D Receptor Inhibits NLRP3 Activation by Impeding Its BRCC3-Mediated Deubiquitination.
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Jul 2020 – Oct 2023Where it's discussed
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X / Twitter23 posts
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YouTube3 videos
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Facebook2 posts
AI synopsis
What people are saying
The discussions reflect appreciation for the research's potential health implications, such as controlling inflammation through vitamin D, with phrases like 'Vitamin D helps prevent it' and mentions of its relevance to COVID and aging, demonstrating both recognition of scientific significance and influence on health narratives.
Most discussions acknowledge the inhibitory role of vitamin D receptor (VDR) on NLRP3 activation, with some posts explicitly referencing the research findings.
Participants show moderate interest, connecting the research to broader health topics like COVID, aging, and nutrition, but some posts divert to unrelated topics or skepticism.
Posts cite mechanisms, implications, or related compounds like caffeine and vitamins, indicating active engagement with the scientific content while some are brief or general.
Several comments suggest that understanding VDR's role could influence health strategies or treatments, though the overall perceived impact varies among users.
Abstract in brief
- The NLRP3 inflammasome is essential for triggering inflammation by activating cytokines like IL-1β and IL-18, and its dysregulation is linked to autoimmune diseases.
- Researchers have discovered that the vitamin D receptor (VDR) acts as a negative regulator for NLRP3, preventing its activation and reducing inflammation.
- This indicates that VDR signaling could be a promising target for treating diseases related to NLRP3 inflammasome activation.
Top posts
Most liked on X and Bluesky@richardursomd Ianamd but noticed <<vitamin D negatively regulates the NLRP3 inflammasome via VDR signaling to effectively inhibit IL-1β secretion.>> https://t.co/Gubuc461Ib
Link between vitamin D and NLRP3 inflammasome VitD Receptor Inhibits NLRP3 Activation by Impeding Its BRCC3-Mediated Deubiquitination, Vitamin D is shown to enhance the vitamin D receptor (VDR)-Mediated Inhibition of NLRP3 Inflammasome Activation https://t.co/Qhx4dZNvbu 18/x
2/2 (thanks again, @fredeyragues) Vitamin D Receptor Inhibits NLRP3 Activation by Impeding Its BRCC3-Mediated Deubiquitination https://t.co/AVWYemrf7J
Wild Effect of Vitamin D on Aging & Longevity https://t.co/ZSsomfm1x9 via @YouTube
RT @Andiesimplelife: @francispouliot_ Vitamin D helps prevent it. https://t.co/RnwSUfrHAM
All mentions
Vitamin D's Role in Aging and Inflammation Regulation
The vitamin D receptor inhibits NLRP3 inflammasome activation by preventing BRCC3-mediated deubiquitination, reducing inflammation, and potentially influencing aging and longevity. This highlights VDR as a target for…
Vitamin D Forms and Their Impact on Inflammation and NLRP3 Activation
Learn how different forms of vitamin D influence inflammation by regulating NLRP3 inflammasome activity and explore potential therapeutic targets for inflammatory diseases.
Vitamin D's Role in Regulating NLRP3 Inflammasome Activation
This video explains how the vitamin D receptor inhibits NLRP3 inflammasome activation, reducing inflammation. The NLRP3 inflammasome is vital for cytokine activation and is linked to autoimmune diseases.
@heniek_htw Published Dec 2019 Vitamin D Receptor Inhibits NLRP3 Activation by Impeding Its BRCC3-Mediated Deubiquitination https://t.co/CiZ5ri6Sxv
The vitamin D receptor inhibits NLRP3 activation. (2) Covid also Drives NLRP3 activation as does Fructose associated uric acid production in the liver once the serum becomes saturated. https://t.co/28I3YIe7cu https://t.co/bt9ZS6FRgJ
https://t.co/SHDKyD8O7B
RT @Woodynist: 2/2 (thanks again, @fredeyragues) Vitamin D Receptor Inhibits NLRP3 Activation by Impeding Its BRCC3-Mediated Deubiquitina…
2/2 (thanks again, @fredeyragues) Vitamin D Receptor Inhibits NLRP3 Activation by Impeding Its BRCC3-Mediated Deubiquitination https://t.co/AVWYemrf7J
RT @jojiswims: https://t.co/Qg3U8U4RJw Potential caffeine downside Vitamin D receptor activation is needed to inhibit the NLRP3 inflammaso…
https://t.co/Qg3U8U4RJw Potential caffeine downside Vitamin D receptor activation is needed to inhibit the NLRP3 inflammasome & caspase-1, a central inflammatory enzyme that activates interleukin cytokines Caffeine decreases vitamin D receptor expression https://t.co/fPE5R1y6l3
You're using the WRONG Vitamin D https://t.co/mFjAIy0W7R via @YouTube
Health medical Nutrition https://t.co/8daxakOcB4
https://t.co/7WevNxFb9s https://t.co/Ydv7nkL8YR
Thomas DeLauer You're using the WRONG Vitamin D https://t.co/9VEIlpGqOy #keto
Link between vitamin D and NLRP3 inflammasome VitD Receptor Inhibits NLRP3 Activation by Impeding Its BRCC3-Mediated Deubiquitination, Vitamin D is shown to enhance the vitamin D receptor (VDR)-Mediated Inhibition of NLRP3 Inflammasome Activation https://t.co/Qhx4dZNvbu 18/x
Wild Effect of Vitamin D on Aging & Longevity https://t.co/ZSsomfm1x9 via @YouTube
Wild Effect of Vitamin D on Aging & Longevity https://t.co/THPpJc9f8x via @YouTube
Vitamin D3 & K2 is one of the most important supplements that you could take. Vitamin C, D3, K2, Quercetin & Zinc, a healthy diet & exercise. Why isn’t the government promoting this? No profits for corrupt politicians & pharmaceutical companies. https://t.co/qDslShmF3C
https://t.co/l8UJCKRmIm https://t.co/Ib7XsotRCn The Best and Worst of Your Week One of the main reasons why losing weight is so hard to accomplish is that each 24 hour period presents a new set of challenges.
https://t.co/bBTsPQ32SF https://t.co/K27at3ONjC The Daunting Risks of Laparoscopic Obesity Surgery Laparoscopic obesity surgery has a list of daunting risks that occur in the post-surgery period. The complicat
RT @robertwrand: @richardursomd Ianamd but noticed <<vitamin D negatively regulates the NLRP3 inflammasome via VDR signaling to effectively…
RT @robertwrand: @richardursomd Ianamd but noticed <<vitamin D negatively regulates the NLRP3 inflammasome via VDR signaling to effectively…
@richardursomd Ianamd but noticed <<vitamin D negatively regulates the NLRP3 inflammasome via VDR signaling to effectively inhibit IL-1β secretion.>> https://t.co/Gubuc461Ib
RT @Andiesimplelife: @francispouliot_ Vitamin D helps prevent it. https://t.co/RnwSUfrHAM
RT @Andiesimplelife: @francispouliot_ Vitamin D helps prevent it. https://t.co/RnwSUfrHAM
https://t.co/LrwIH9NfRk