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Neuroimage Clin January 2021 PMID 31978826

Hippocampal plasticity underpins long-term cognitive gains from resistance exercise in MCI.

Kathryn M Broadhouse, Maria Fiatarone Singh, Chao Suo, Nicola Gates, Wei Wen, Henry Brodaty, Nidhi Jain, Guy C Wilson, Jacinda Meiklejohn, Nalin Singh, Bernhard T Baune, Michael Baker, Nasim Foroughi, Yi Wang, Nicole Kochan

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Mentions

130
Peak: 26 in Feb 2020
across 5 sources since Jan 2020

Extended reach

161,162
potential audience

Total likes

173

Video views

8,514

Mentions per month

Jan 2020 – Jul 2025

Where it's discussed

  • News81 articles
  • X / Twitter39 posts
  • Blogs4 articles
  • YouTube3 videos
  • Facebook3 posts

AI synopsis

What people are saying

Numerous posts highlight the significance of hippocampal plasticity and resistance training in mitigating cognitive decline, with phrases like 'high-impact,' 'protects the brain,' and 'crucial for preventing Alzheimer's.' The seriousness and enthusiasm in the tone, along with references to practical applications and upcoming interventions, underscore the high level of engagement and perceived importance of the research.

AgreementModerate agreement

Most discussions acknowledge and support the findings about hippocampal plasticity and resistance exercise benefits in MCI, showing general agreement.

InterestHigh interest

The posts demonstrate high interest, with many calling the research 'important,' 'high-impact,' or referencing its significance for preventing dementia.

EngagementModerate engagement

Users actively share and summarize key findings, quote parts of the study, and praise the research team, indicating moderate but meaningful engagement.

ImpactModerate impact

The discussions suggest the study could influence future health and exercise practices for at-risk populations, showing a moderate potential impact.

Abstract in brief

  • Dementia currently affects 47 million people globally, with projections suggesting this number could triple by 2050, highlighting the need for potential prevention strategies.
  • The SMART trial investigated the long-term effects of resistance training on the brains of individuals with Mild Cognitive Impairment (MCI), finding that resistance exercise significantly protects key brain areas from atrophy linked to Alzheimer's disease.
  • Results showed that participants engaged in progressive resistance training (PRT) experienced notable cognitive improvements and structural brain protection compared to those in sham training groups, with specific areas of the hippocampus benefiting from the exercise even a year after the training ended.
Read the full abstract

Top posts

Most liked on X and Bluesky
Jose Antonio PhD
@JoseAntonioPhD · X

6 months of high intensity resistance exercise is capable of not only promoting better cognition in those with MCI, but also protecting AD-vulnerable hippocampal subfields from degeneration for at least 12 months post-intervention. https://t.co/TTqva4FVci

Feb 7, 2020 · 58 likes · 14 shares · 22,197 followers View post →
J P Fanton
@HealthyFellow · X

#Hippocampal #plasticity underpins long-term #cognitive gains from #resistance #exercise in #MCI https://t.co/SaMFIEg4Im Attn: @NathanMDCunha @NaumovskiNenad @Domenico_Sergi9 @AndrewMcKune @NuroUnderground @BrainHealthProj @NeuroscienceNew #brain #cardiovascular

Jan 25, 2020 · 6 likes · 3 shares · 26,025 followers View post →
Christoph Burch
@ChristophBurch · X

Hippocampal Plasticity Underpins Long-Term Cognitive Gains From Resistance Exercise in Mild Cognitive Impairment (MCI) Kathryn M Broadhouse et al. Neuroimage Clin. 2020 #openaccess https://t.co/bdJP3PrgJ4 https://t.co/DBLFCxq7HR

Apr 21, 2020 · 5 likes · 2 shares · 15,346 followers View post →
Tidbit - Graphical Abstract Maker
@readatidbit · X

Resistance training for preventing #Alzheimers ? Check out this #visualabstract https://t.co/Ka7SKuVumC https://t.co/2UlKdJNObm

Aug 8, 2021 · 4 likes · 703 followers View post →
Tommy Lundberg
@TLexercise · X

RE

Feb 10, 2020 · 3 likes · 7,801 followers View post →
Jon Chung
@drjonathanchung · X

Hippocampal plasticity underpins long-term cognitive gains from resistance exercise in mild cognitive impairment

Oct 6, 2024 · 2 likes · 2,072 followers View post →

All mentions

ニア@関西体刺し一門代表
@kongai_san2 · X

まともに筋トレしてへんから自分が言ったことすぐ忘れるんや！https://t.co/Nr8pHDsFOD

Jul 14, 2025 · 2 likes · 926 followers View post →
Jon Chung
@drjonathanchung · X

Hippocampal plasticity underpins long-term cognitive gains from resistance exercise in mild cognitive impairment

Oct 6, 2024 · 2 likes · 2,072 followers View post →
Madam Mitochondria
@Madam_Mito · X

@AlgoTradeAll @MedEckardt @de_bose @KiesowPaul @yeeseak @yeesak @daveasprey https://t.co/QnlpfUOlAU Resistance training is extremely important for reducing risk.

Feb 1, 2023 · 10,590 followers View post →
Tidbit - Graphical Abstract Maker
@readatidbit · X

Resistance training for preventing #Alzheimers ? Check out this #visualabstract https://t.co/Ka7SKuVumC https://t.co/2UlKdJNObm

Aug 8, 2021 · 4 likes · 703 followers View post →
Sarcopenia_papers
@sarc_papers · X

Hippocampal plasticity underpins long-term cognitive gains from resistance exercise in MCI. https://t.co/xDdzLPvLH5 https://t.co/Ib95nCZ3S8

Jan 5, 2021 · 553 followers View post →
Roger Hilfiker
@RogerHilfiker · X

RT @ChristophBurch: Hippocampal Plasticity Underpins Long-Term Cognitive Gains From Resistance Exercise in Mild Cognitive Impairment (MCI)…

Apr 21, 2020 · 2 shares · 1,617 followers View post →
Christoph Burch
@ChristophBurch · X

Hippocampal Plasticity Underpins Long-Term Cognitive Gains From Resistance Exercise in Mild Cognitive Impairment (MCI) Kathryn M Broadhouse et al. Neuroimage Clin. 2020 #openaccess https://t.co/bdJP3PrgJ4 https://t.co/DBLFCxq7HR

Apr 21, 2020 · 5 likes · 2 shares · 15,346 followers View post →
Peter Dashevici
@expreacher · X

Strength training can protect brain from degeneration in those at risk of Alzheimer’s https://t.co/6VFJ0JGKc8 Multi institutional research Hippocampal plasticity underpins long-term cognitive gains from resistance exercise in MCI https://t.co/US88XOwTNE

Mar 9, 2020 · 1 like · 1,988 followers View post →
Dr. Roger A. Fielding, PhD
@RogerFielding5 · X

RT @MarcasBamman: Now this is high-impact stuff from an outstanding team! Hippocampal Plasticity Underpins Long-Term Cognitive Gains From…

Feb 17, 2020 · 6 shares · 689 followers View post →
Nick Krontiris
@nick_krontiris · X

Hippocampal plasticity underpins long-term cognitive gains from resistance exercise in MCI (open access) #exercise #fitness #fit #FitFam #FitLife #FitnessAddict #Workout #TrainHard #GymLife #GymTime #muscle #strength #lift #GetStrong #aging #Alzheimers

Feb 12, 2020 · 19,312 followers View post →
Leslie Muse
@LeslieMuse · X

Hippocampal plasticity underpins long-term cognitive gains from resistance exercise in MCI - ScienceDirect https://t.co/yoFU5hGo1U

Feb 11, 2020 · 61 followers View post →
Tommy Lundberg
@TLexercise · X

RE

Feb 10, 2020 · 3 likes · 7,801 followers View post →
Raul
@RaulM06 · X

RT @JoseAntonioPhD: 6 months of high intensity resistance exercise is capable of not only promoting better cognition in those with MCI, but…

Feb 8, 2020 · 14 shares · 851 followers View post →
中武 壮以知
@soichinakatake · X

「6か月間の高強度の筋トレは、認知障害患者の認知を向上させ、介入後少なくとも12か月間、海馬を変性から保護できることを示している」 Hippocampal Plasticity Underpins Long-Term Cognitive Gains From Resistance Exercise in MCI https://t.co/P3fENJuCts

Feb 7, 2020 · 137 followers View post →
Juan Carlos Bórquez
@jcborquezp · X

RT @JoseAntonioPhD: 6 months of high intensity resistance exercise is capable of not only promoting better cognition in those with MCI, but…

Feb 7, 2020 · 14 shares · 232 followers View post →
Alexandre Langis
@AlexandreLangis · X

RT @JoseAntonioPhD: 6 months of high intensity resistance exercise is capable of not only promoting better cognition in those with MCI, but…

Feb 7, 2020 · 14 shares · 89 followers View post →
Eisnel Hdez
@EisnelHR · X

RT @JoseAntonioPhD: 6 months of high intensity resistance exercise is capable of not only promoting better cognition in those with MCI, but…

Feb 7, 2020 · 14 shares · 26 followers View post →
Trainervickk
@TrainerVickk · X

RT @JoseAntonioPhD: 6 months of high intensity resistance exercise is capable of not only promoting better cognition in those with MCI, but…

Feb 7, 2020 · 14 shares · 343 followers View post →
DrHorwitz
@DrHorwitz · X

RT @JoseAntonioPhD: 6 months of high intensity resistance exercise is capable of not only promoting better cognition in those with MCI, but…

Feb 7, 2020 · 14 shares · 13,743 followers View post →
Cindy Kugler
@Exspec85 · X

RT @JoseAntonioPhD: 6 months of high intensity resistance exercise is capable of not only promoting better cognition in those with MCI, but…

Feb 7, 2020 · 14 shares · 234 followers View post →
SmartNutrition
@SmartNutrition1 · X

RT @JoseAntonioPhD: 6 months of high intensity resistance exercise is capable of not only promoting better cognition in those with MCI, but…

Feb 7, 2020 · 14 shares · 2,654 followers View post →
Daniel Moreno
@dmorenoost · X

RT @JoseAntonioPhD: 6 months of high intensity resistance exercise is capable of not only promoting better cognition in those with MCI, but…

Feb 7, 2020 · 14 shares · 641 followers View post →
Jon Denoris
@JonDenoris · X

RT @JoseAntonioPhD: 6 months of high intensity resistance exercise is capable of not only promoting better cognition in those with MCI, but…

Feb 7, 2020 · 14 shares · 611 followers View post →
Alex
@AlexViKu · X

RT @MarcasBamman: Now this is high-impact stuff from an outstanding team! Hippocampal Plasticity Underpins Long-Term Cognitive Gains From…

Feb 7, 2020 · 6 shares · 97 followers View post →
Jose
@Jose_8523 · X

RT @JoseAntonioPhD: 6 months of high intensity resistance exercise is capable of not only promoting better cognition in those with MCI, but…

Feb 7, 2020 · 14 shares · 291 followers View post →
eleanorina
@_eleanorina · X

RT @JoseAntonioPhD: 6 months of high intensity resistance exercise is capable of not only promoting better cognition in those with MCI, but…

Feb 7, 2020 · 14 shares · 3,180 followers View post →
ᴰᴬᴴᴸᴵᴬ
@dahlia8888_ · X

RT @JoseAntonioPhD: 6 months of high intensity resistance exercise is capable of not only promoting better cognition in those with MCI, but…

Feb 7, 2020 · 14 shares · 415 followers View post →
Jose Antonio PhD
@JoseAntonioPhD · X

6 months of high intensity resistance exercise is capable of not only promoting better cognition in those with MCI, but also protecting AD-vulnerable hippocampal subfields from degeneration for at least 12 months post-intervention. https://t.co/TTqva4FVci

Feb 7, 2020 · 58 likes · 14 shares · 22,197 followers View post →
James McKendry, Ph.D.
@james_mckendry · X

RT @MarcasBamman: Now this is high-impact stuff from an outstanding team! Hippocampal Plasticity Underpins Long-Term Cognitive Gains From…

Feb 7, 2020 · 6 shares · 1,311 followers View post →
Garrett Hester, PhD
@GarrettHester2 · X

RT @MarcasBamman: Now this is high-impact stuff from an outstanding team! Hippocampal Plasticity Underpins Long-Term Cognitive Gains From…

Feb 7, 2020 · 6 shares · 279 followers View post →
Abigail Mackey
@AbigailMackey1 · X

RT @MarcasBamman: Now this is high-impact stuff from an outstanding team! Hippocampal Plasticity Underpins Long-Term Cognitive Gains From…

Feb 7, 2020 · 6 shares · 3,717 followers View post →
Tommy Lundberg
@TLexercise · X

RT @MarcasBamman: Now this is high-impact stuff from an outstanding team! Hippocampal Plasticity Underpins Long-Term Cognitive Gains From…

Feb 7, 2020 · 6 shares · 7,801 followers View post →
louis c waddell jr md
@louiscwaddellj1 · X

https://t.co/rmhLFLBzLM resistance exercise may be good medicine for the hippocampus, at least it seemed to be in these MCI patiens

Feb 6, 2020 · 7 followers View post →
UniSCResearchBank
@USCResearchBank · X

#OA article: Hippocampal plasticity underpins long-term cognitive gains from resistance exercise in MCI (2020) @Kbroadhouse et al. DOWNLOAD HERE: https://t.co/wCMs6o70kw https://t.co/7FFfouHryi

Feb 3, 2020 · 960 followers View post →
Christine Ross DVM
@AnimalHRV · X

RT @HealthyFellow: #Hippocampal #plasticity underpins long-term #cognitive gains from #resistance #exercise in #MCI https://t.co/SaMFIEg4Im…

Jan 28, 2020 · 3 shares · 1,495 followers View post →
Prof Nenad Naumovski (PhD)
@NaumovskiNenad · X

RT @HealthyFellow: #Hippocampal #plasticity underpins long-term #cognitive gains from #resistance #exercise in #MCI https://t.co/SaMFIEg4Im…

Jan 25, 2020 · 3 shares · 1,223 followers View post →
Nathan M D'Cunha
@NathanMDCunha · X

RT @HealthyFellow: #Hippocampal #plasticity underpins long-term #cognitive gains from #resistance #exercise in #MCI https://t.co/SaMFIEg4Im…

Jan 25, 2020 · 3 shares · 1,480 followers View post →
J P Fanton
@HealthyFellow · X

#Hippocampal #plasticity underpins long-term #cognitive gains from #resistance #exercise in #MCI https://t.co/SaMFIEg4Im Attn: @NathanMDCunha @NaumovskiNenad @Domenico_Sergi9 @AndrewMcKune @NuroUnderground @BrainHealthProj @NeuroscienceNew #brain #cardiovascular

Jan 25, 2020 · 6 likes · 3 shares · 26,025 followers View post →
Paperbirds_Neurology
@PaperbirdsN · X

New article: Hippocampal plasticity underpins long-term cognitive gains from resistance exercise in MCI. https://t.co/nmwukaPQ8o #alzheimers #neurology

Jan 25, 2020 · 456 followers View post →