April 2020 PMID 32001253

Anaphylaxis-a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment, Development and Evaluation (GRADE) analysis.

Marcus S Shaker, Dana V Wallace, David B K Golden, John Oppenheimer, Jonathan A Bernstein, Ronna L Campbell, Chitra Dinakar, Anne Ellis, Matthew Greenhawt, David A Khan, David M Lang, Eddy S Lang, Jay A Lieberman, Jay Portnoy, Matthew A Rank

Mentions

73
Peak: 13 in Apr 2021
across 5 sources since May 2020

Extended reach

53,400
potential audience

Total likes

34

Video views

644

Mentions per month

May 2020 – Mar 2025

Where it's discussed

  • News38 articles
  • X / Twitter19 posts
  • Facebook6 posts
  • Blogs6 articles
  • YouTube4 videos

AI synopsis

What people are saying

The overall tone demonstrates strong agreement and high interest, with posts emphasizing the importance of epinephrine and the ineffectiveness of antihistamines for biphasic reactions, such as describing it as a 'game changer.' Although posts show active engagement through sharing detailed opinions and referencing the publication, the perceived impact remains moderate, as some discussions focus on reaffirming existing practices rather than widespread changes.

AgreementModerate agreement

Most posts note that the publication aligns with current best practices, supporting the emphasis on epinephrine as the primary treatment.

InterestHigh interest

Readers show high interest by frequently referencing the article and actively discussing treatment strategies and implications.

EngagementModerate engagement

Many discussions include references to specific guidelines and practice updates, indicating thoughtful engagement.

ImpactModerate impact

The social discussions reflect an awareness of how this publication might influence clinical practices, though some appear to treat it as informational rather than transformative.

Abstract in brief

  • Anaphylaxis is a potentially life-threatening allergic reaction with diverse symptoms, and severe cases or those needing multiple epinephrine doses are at higher risk for biphasic responses.
  • Current evidence indicates that antihistamines and glucocorticoids are not effective in preventing biphasic anaphylaxis, though they may be useful as premedication in specific situations like certain chemotherapy or allergen immunotherapy protocols.
  • Epinephrine remains the primary treatment for both uniphasic and biphasic anaphylaxis, and all patients should be monitored until symptoms resolve, receive education on managing future episodes, and be instructed on trigger avoidance and self-injection of epinephrine.

Top posts

Most liked on X and Bluesky
David Alvarado
@DrDavid_algz7 · X

doi: 10.1016/j.jaci.2020.01.017.

Apr 2, 2021 · 10 likes · 4 shares · 15 followers View post →
หนอนน้อยอ่านเปเปอร์
@AcademicWorm · X

มาอัปเดตกัน Anaphylaxis-a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment, Development and Evaluation (GRADE) analysis. J Allergy Clin Immunol 2020

May 5, 2020 · 6 likes · 2 shares · 166 followers View post →
David Alvarado
@DrDavid_algz7 · X

doi: 10.1016/j.jaci.2020.01.017. #wakandaurg Declaraciones de buenas prácticas adicionales: 1. Administrar

Apr 2, 2021 · 6 likes · 3 shares · 15 followers View post →
Dra.Stimuplex
@maladeras · X

@DrCriticalCare doi: 10.1016/j.jaci.2020.01.017. Epub 2020 Jan 28

Mar 29, 2022 · 3 likes · 75 followers View post →
David Alvarado
@DrDavid_algz7 · X

doi: 10.1016/j.jaci.2020.01.017. #wakandaurg https://t.co/wLhxj6azy9

Apr 2, 2021 · 2 likes · 2 shares · 15 followers View post →
永井友基@みんほす!
@yukina_minhos · X

Uptodateや以下参照してます https://t.co/e8F6q8kZSj

Mar 18, 2022 · 1 like · 18,168 followers View post →

All mentions

Dra.Stimuplex
@maladeras · X

@DrCriticalCare doi: 10.1016/j.jaci.2020.01.017. Epub 2020 Jan 28

Mar 29, 2022 · 3 likes · 75 followers View post →
永井友基@みんほす!
@yukina_minhos · X

Uptodateや以下参照してます https://t.co/e8F6q8kZSj

Mar 18, 2022 · 1 like · 18,168 followers View post →
PHSTeaching
@PMCHPHS · X

Anaphylaxis-a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment, Develo… https://t.co/LuwNgVuYci

Apr 22, 2021 · 66 followers View post →
La RESIstance TLX
@laresistanceTLX · X

RT @DrDavid_algz7: doi: 10.1016/j.jaci.2020.01.017. #wakandaurg https://t.co/wLhxj6azy9

Apr 6, 2021 · 2 shares · 988 followers View post →
La RESIstance TLX
@laresistanceTLX · X

RT @DrDavid_algz7: doi: 10.1016/j.jaci.2020.01.017.

Apr 6, 2021 · 4 shares · 988 followers View post →
La RESIstance TLX
@laresistanceTLX · X

RT @DrDavid_algz7: doi: 10.1016/j.jaci.2020.01.017. #wakandaurg Declaraciones de buenas prácticas adicionales: 1. Administrar

Apr 6, 2021 · 3 shares · 988 followers View post →
David Abarca
@abarcvs · X

RT @DrDavid_algz7: doi: 10.1016/j.jaci.2020.01.017. #wakandaurg Declaraciones de buenas prácticas adicionales: 1. Administrar

Apr 2, 2021 · 3 shares · 824 followers View post →
David Abarca
@abarcvs · X

RT @DrDavid_algz7: doi: 10.1016/j.jaci.2020.01.017.

Apr 2, 2021 · 4 shares · 824 followers View post →
Tirof-Ivan
@Ilescasivan · X

RT @DrDavid_algz7: doi: 10.1016/j.jaci.2020.01.017.

Apr 2, 2021 · 4 shares · 1,473 followers View post →
Dive Bañuelos
@Dr_Dive · X

RT @DrDavid_algz7: doi: 10.1016/j.jaci.2020.01.017. #wakandaurg Declaraciones de buenas prácticas adicionales: 1. Administrar

Apr 2, 2021 · 3 shares · 6,954 followers View post →
Dive Bañuelos
@Dr_Dive · X

RT @DrDavid_algz7: doi: 10.1016/j.jaci.2020.01.017.

Apr 2, 2021 · 4 shares · 6,954 followers View post →
Dive Bañuelos
@Dr_Dive · X

RT @DrDavid_algz7: doi: 10.1016/j.jaci.2020.01.017. #wakandaurg https://t.co/wLhxj6azy9

Apr 2, 2021 · 2 shares · 6,954 followers View post →
David Alvarado
@DrDavid_algz7 · X

doi: 10.1016/j.jaci.2020.01.017. #wakandaurg Declaraciones de buenas prácticas adicionales: 1. Administrar

Apr 2, 2021 · 6 likes · 3 shares · 15 followers View post →
David Alvarado
@DrDavid_algz7 · X

doi: 10.1016/j.jaci.2020.01.017.

Apr 2, 2021 · 10 likes · 4 shares · 15 followers View post →
David Alvarado
@DrDavid_algz7 · X

doi: 10.1016/j.jaci.2020.01.017. #wakandaurg https://t.co/wLhxj6azy9

Apr 2, 2021 · 2 likes · 2 shares · 15 followers View post →
Girish Narayan
@ErGirishN · X

https://t.co/qjjqyu81da

May 26, 2020 · 124 followers View post →
Mingtian 明天
@jalatbus · X

RT @AcademicWorm: มาอัปเดตกัน Anaphylaxis-a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment,…

May 5, 2020 · 2 shares · 366 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @AcademicWorm: มาอัปเดตกัน Anaphylaxis-a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment,…

May 5, 2020 · 2 shares · 6,712 followers View post →
หนอนน้อยอ่านเปเปอร์
@AcademicWorm · X

มาอัปเดตกัน Anaphylaxis-a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment, Development and Evaluation (GRADE) analysis. J Allergy Clin Immunol 2020

May 5, 2020 · 6 likes · 2 shares · 166 followers View post →