وبكذا وجدوا ان ١) هذا الفيروس مشابه لسارس الى حد كبير اكثر من فيروس ميرس وايضاً وجدوا ٢) ان S-protein الموجود في فيروس سارس يشبه الموجود في هذا الفيروس .. https://t.co/lswdl6IqoR https://t.co/CuIrYKJtsb
Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission.
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AI synopsis
What people are saying
The discussions highlight the public's concern regarding the origins and risks associated with the coronavirus. For instance, several users mention the artificial modifications of the virus, with phrases like 'artificially designed' indicating alarm and curiosity. Others discuss the spike protein's interaction with the human ACE2 receptor, emphasizing the potential for human transmission by using emphatic language and urgent tones, which elevates the perceived importance of the findings.
Most discussions reflect a general support for the findings of the publication, though some express skepticism over specific claims.
The topics of viral evolution and transmission risk generate significant curiosity among participants.
While many users are engaged in the discussion, few delve into the technical aspects of research methods or detailed implications.
There is a strong belief that the publication holds significant implications for public health and understanding of the virus.
Abstract in brief
- The novel coronavirus, which originated from the Wuhan outbreak, has undergone significant evolutionary changes that affect its transmission capabilities.
- Research focuses on modeling the virus's spike protein, a critical component for the virus to infect human cells.
- Understanding these changes helps assess the risk of human transmission and informs public health responses.
Top posts
Most liked on X and Bluesky@abeaube @Technocrat21mb @ItIsIMack @CausticBitchNC @RussellSieg @ShellyPersisted @kelly2277 @ml_bear https://t.co/O6C7AAAZxm
2019-nCoVのゲノム研究→ウイルスゲノムの配列を見る限り、最も近縁はコウモリのコロナウィルスHKU9-1。 SARS-CoVと同様にS-proteinが受容体(アンジオテンシン変換酵素 2)と結合する可能性。https://t.co/fwmN6V2zAO
なるほど、新型コロナウイルスは細胞表面のACE2(アンギオテンシン変換酵素2)受容体(SARSウイルスもこれを利用)を介してヒト肺胞上皮細胞に感染すると考えられるわけか。https://t.co/4dOv2Qoohs 中国発の論文https://t.co/KP2wZB49D2 ではタンパク質3次元構造の予測から受容体結合力をSARSと比較
21日,中科院上海巴斯德研究所、军事医学研究院国家应急防控药物工程技术研究中心和中科院分子植物中心合成生物学重点实验室合作在线发表“Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission” #对人感染力很强 https://t.co/jSIouddvkS
Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission https://t.co/WWWflNiGHi
All mentions
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This video explores the evolution of the novel coronavirus from the Wuhan outbreak. It focuses on modeling the virus's spike protein, which is crucial for human infection, to assess transmission risk and inform public…
Evolution of the Novel Coronavirus and Its Transmission Risks
The video explores the evolution of the novel coronavirus originating from the Wuhan outbreak. It highlights significant changes in its spike protein, critical for the virus's ability to infect human cells, aiding in…
but https://t.co/Y5AW1RsYwW
Evolution of the novel coronavirus from the ongoing Wuhan outbreak an... - https://t.co/kLzLs7pnKB
RT @criticalWnews: Quatre des protéines les plus importantes du #SARSCoV2 (résidus d'acides aminés d'interface, 4 insertions uniques dans…
Quatre des protéines les plus importantes du #SARSCoV2 (résidus d'acides aminés d'interface, 4 insertions uniques dans la glycoprotéine avancée aux positions 442, 472, 479, 487) ont été modifiées artificiellement (étude chinoise 16 Janvier 2020) #COVID19 https://t.co/qVwlEHV0Km
RT @parasite2006: なるほど、新型コロナウイルスは細胞表面のACE2(アンギオテンシン変換酵素2)受容体(SARSウイルスもこれを利用)を介してヒト肺胞上皮細胞に感染すると考えられるわけか。https://t.co/4dOv2Qoohs 中国発の論文https:…
Il serait également bon de mentionner l'étude chinoise publiée en ligne le 21 Janvier 2020 qui suggère à demi-mot que le #SARSCoV2 a été artificiellement conçu. "Evolution of the novel coronavirus from the ongoing Wuhan outbreak .." https://t.co/s8Zm48Ep61 https://t.co/L6frPWaxtA
Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission @BillGertz I’ve read of efforts to manipulate this virus for human contagion. Was the US jointly funding this ? https://t.co/m5RqSneLG3
@TonyBaduy @PeterDClack @B_Bolshevik100 @HMS_Indomitable @flyonthewall182 @TheDisproof @AtomsksSanakan @fishbonker66 @TMV_Intel @d_e_mol @8BrianVogel4 @91996340e81d45a @KSulza @JimBabw19270992 @DawnTJ90 @JosephsEddy @MikeDel21893959 @NoelTurner194 @nicolasDenver @fcmfcs2019 @katiebecker16 @swcrisis @sueytonius @legjoints @PolAnimalAus @GillesnFio @AOECOIN @ClimateSkeptic4 @corchem @Samanth71003012 @MedBennett @OG_Advisors @GuitarMan59LP @tracemetalclean @DMRDartford @JackJsherebkin @MonkeyMyBack @BridgetAshmore @D16584667 @drwaheeduddin @Kenneth72712993 @TinFoilAwards @UreyZen @RoyPentland @GeoffSchuler @mentalmal1 @ubikkgoat @JohnBrennan @Comey There is no reference to any pangolin strain in the Xu letter cited. https://t.co/umzNG4sKpn… And except for the RBM region where the Pangolin strain is almost identical, the rest of the genome is quite different. CoV2 however is 96% identical t
@Leitadas_L0en @FlavioDoutor Quando nego tiver com preguiça e zoar o documentário sem assistir manda ele ler os artigos e refutar na revista. O documentário é bom! Aqui os links: https://t.co/CM0gTnkL4j https://t.co/srvnqttaFB https://t.co/rThujMT6UR https://t.co/TiBHtGPRdo
[Title]Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modelling of its spike protein for risk of human transmission.
pdf : https://t.co/PXMgTw1JYw authors : Xintian Xu 1†, Ping Chen 2,5†, Jingfang Wang 3†, Jiannan Feng 4, Hui Zhou 2, Xuan Li 2*, Wu Zhong 4* & Pei Hao 1,5*
Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission Received January 16, 2020; accepted January 20, 2020; published online January 21, 2020 SCIENCE CHINA Life Sciences https://t.co/DqNH6W6iij
I call gene scientists to replicate the result of the following paper: https://t.co/aDQP7Wm8uG and investigate on “binding free energy” and “capacity of contagion”. https://t.co/2ddo2mlShk
https://t.co/0bIx6S5UTh
PubMed: Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission.: Related Articles Evolution of the novel coronavirus from the ongoing Wuhan… https://t.co/8f7X82ZipB #coronavirus #SARS_CoV_2 #covid19
RT @KevinAHarperVO: Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human…
Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission https://t.co/WWWflNiGHi
https://t.co/WWWflNiGHi
Hier is 'n wetenskaplike geskrif vanuit Sjina self oor die virus. Die verkorte skakel is: https://t.co/jwQhJkL7fN As dié skakel nie werk nie hier's die oorspronklike direkte skakel; https://t.co/7cz8c8nhM5 Die opskrif van die geskrif is soos dié skermgreep. https://t.co/oxctcWnQy5
RT @syntropian: references https://t.co/kN5FD20uyu https://t.co/swgAbiSc54 https://t.co/H6A63KDQ63 https://t.co/GvgvfDA8sW
Keep up with the research on the world's most popular topic - all thanks to #Openaccess papers
@BiyaAli9 @ObnoxiousBrat Hi Biya, I am sure you shared this with purest of intentions however I have reason to believe this isn't accurate and I hope you can remove it. 1. Size is 50-200 um, and not all masks work https://t.co/WwH7xmNqY9 https://t.co/l4zZDKfJhh 2. Iran regularly has higher temp
RT @parasite2006: なるほど、新型コロナウイルスは細胞表面のACE2(アンギオテンシン変換酵素2)受容体(SARSウイルスもこれを利用)を介してヒト肺胞上皮細胞に感染すると考えられるわけか。https://t.co/4dOv2Qoohs 中国発の論文https:…
@nanne_ny หรือมีความรู้งูงูปลาปลา จับแพะชนแกะไปหมดเลย ลองอ่านดูได้นะคะ ขอบคุณที่บอก อ่านสนุกเหมือนกัน fake news นี่มันเริ่มอย่างนี้นี่เอง https://t.co/tdFwJA1W9y
@tcabarrus C'est une course contre la montre. Les chauves-souris,le passent à un animal intermédiaire ou+ et,ça rendrait malades nos proches.. Pasteur disait: le microbe n'est rien, le milieu c'est tout. On
@CTGgn @georgebest1969 yes, and here are other 3 related paper: https://t.co/1ADoLzaUxs https://t.co/gGwNhgvDfu https://t.co/RxdGQ45gun
RT @parasite2006: なるほど、新型コロナウイルスは細胞表面のACE2(アンギオテンシン変換酵素2)受容体(SARSウイルスもこれを利用)を介してヒト肺胞上皮細胞に感染すると考えられるわけか。https://t.co/4dOv2Qoohs 中国発の論文https:…
なるほど、新型コロナウイルスは細胞表面のACE2(アンギオテンシン変換酵素2)受容体(SARSウイルスもこれを利用)を介してヒト肺胞上皮細胞に感染すると考えられるわけか。https://t.co/4dOv2Qoohs 中国発の論文https://t.co/KP2wZB49D2 ではタンパク質3次元構造の予測から受容体結合力をSARSと比較
RT @kai958531911: 2019-nCoVの進化とヒトへ伝播するスパイクタンパク質のモデリング Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of i…
2019-nCoVの進化とヒトへ伝播するスパイクタンパク質のモデリング Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission | SpringerLink https://t.co/jwpepRjzv3
New article: Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission. https://t.co/ejuxs1N0KG #coronavirus #wuhan #2019ncov
根据这篇论文 https://t.co/hmyJu4LvLv 新冠状病毒的S蛋白质和SARS的相比,整体相似性不高,但是RBD domain的相似性很高,但是RBD domain里跟ACE2结合起决定作用的5个氨基酸残基被替换了4个,导致跟ACE2的结合能降低了35%,但是仍然具备很强的结合能力。#coronavirus #武汉病毒
despite its sequence diversity with SARS-CoV S-protein. Thus poses a significant public health risk for human transmission via the S-protein–ACE2 binding pathway. https://t.co/SRiax8p5B4
Another serious paper on the structure of 2019-nCoV: https://t.co/5ot4dDRhkk Xin Xu et al, Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission, Life Sciences, Science China, 21st January 2020
@zerohedge Chinese men have increased incidence of ACE2 polymorphisms. ACE2 is believed to be the binding site. ACE2 is on the X chromosome. “Thus the Wuhan CoV poses a significant public health risk for human transmission via the S-protein–ACE2 binding pathway.” https://t.co/L8usNg6Wsg
Additional info https://t.co/5EtBoSF5dN
@MattyMcClain @MackayIM @maiamajumder @biorxivpreprint I've got 2 more papers you might have seen but interesting nonetheless. https://t.co/p5dodq4xg0 https://t.co/9dbH4oXZCE
Consider that A. The #coronavirus family from SARS and this virus enter the body using the Angiotensin II receptor. (Paper from last Tuesday, but they knew it before) https://t.co/vnAhRJDPAf And B. We luckily HAVE generic Receptor Blockers for Angiotensin II
RT @syntropian: references https://t.co/kN5FD20uyu https://t.co/swgAbiSc54 https://t.co/H6A63KDQ63 https://t.co/GvgvfDA8sW
@del_amire Kalau mau baca mir : https://t.co/q5SIFb9hsh
惊讶的是,SARS-CoV 中五个重要的界面氨基酸残基中的四个:442、472、479和487位被替换了!替换之后,武汉冠状病毒S蛋白和SARS冠状病毒S蛋白在RBD结构域中,依然共享几乎相同的3-D结构。https://t.co/sGhp9mOxdk
Or consider that A. The #coronavirus family from SARS and this virus enter the body using the Angiotensin II receptor. (Paper from last Tuesday, but they knew it before) https://t.co/vnAhRJDPAf And B. We luckily HAVE generic Receptor Blockers for Angiotensin II #BellLetsTaIk
references https://t.co/kN5FD20uyu https://t.co/swgAbiSc54 https://t.co/H6A63KDQ63 https://t.co/GvgvfDA8sW
Mais surtout l'étude chinoise, utilisée pour étayer la rumeur, ne formule qu'une hypothèse et ne conclut pas formellement que la chauve-souris est l'animal "réservoir" du coronavirus et qu'elle l'a transmis à l'homme https://t.co/Dx9p7NFWOR #Wuhan #coronavirus
Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission https://t.co/htFUIJgsAb
RT @AlharthiMeshari: وبكذا وجدوا ان ١) هذا الفيروس مشابه لسارس الى حد كبير اكثر من فيروس ميرس وايضاً وجدوا ٢) ان S-protein الموجود في في…
وبكذا وجدوا ان ١) هذا الفيروس مشابه لسارس الى حد كبير اكثر من فيروس ميرس وايضاً وجدوا ٢) ان S-protein الموجود في فيروس سارس يشبه الموجود في هذا الفيروس .. https://t.co/lswdl6IqoR https://t.co/CuIrYKJtsb
Not that anybody cares, but here are some actual, fact-based data drawn from newly-published #research on the current strains of the #coronavirus making news these days. #nCoV2019 https://t.co/fbN1Yugj4e
@wongkim728 https://t.co/21aqOOojgw
RT @ThomasS4217: @abeaube @Technocrat21mb @ItIsIMack @CausticBitchNC @RussellSieg @ShellyPersisted @kelly2277 @ml_bear https://t.co/O6C7AAA…
@abeaube @Technocrat21mb @ItIsIMack @CausticBitchNC @RussellSieg @ShellyPersisted @kelly2277 @ml_bear https://t.co/O6C7AAAZxm
RT @Cloud__Movement: @zhanglifan @hopefulland 根据在本月16日发表在科技杂志上的论文宣称: 该冠状病毒已经被军方实验室彻底研究,鸣谢部分声称研究经费源于2018年的科技创新基金。 https://t.co/DLP4YsmA8D…
Evolution of the novel coronavirus from the ongoing Wuhan outbreak an... - https://t.co/wtnUITGSah
RT @Lisa_Crossman: @benhwhite Sharing ancestry with Bat coronavirus! https://t.co/B1JWhSfRCc
@benhwhite Sharing ancestry with Bat coronavirus! https://t.co/B1JWhSfRCc
@evilinside44 @linyuanyuan89 https://t.co/f9NKVG9oV1
RT @MarcGozlan: The #Wuhan #nCoV shares with the SARS #coronavirus a common ancestor that resembles the bat coronavirus HKU9-1. The RBD dom…
RT @MarcGozlan: The #Wuhan #nCoV shares with the SARS #coronavirus a common ancestor that resembles the bat coronavirus HKU9-1. The RBD dom…
RT @MarcGozlan: The #Wuhan #nCoV shares with the SARS #coronavirus a common ancestor that resembles the bat coronavirus HKU9-1. The RBD dom…
RT @MarcGozlan: The #Wuhan #nCoV shares with the SARS #coronavirus a common ancestor that resembles the bat coronavirus HKU9-1. The RBD dom…
The #Wuhan #nCoV shares with the SARS #coronavirus a common ancestor that resembles the bat coronavirus HKU9-1. The RBD domain of the Wuhan CoV S-protein supports strong interaction with human ACE2 molecules https://t.co/Elh9fAdPUD #nCoV2019 https://t.co/wpm7zLAaEO
2019-nCoVのゲノム研究→ウイルスゲノムの配列を見る限り、最も近縁はコウモリのコロナウィルスHKU9-1。 SARS-CoVと同様にS-proteinが受容体(アンジオテンシン変換酵素 2)と結合する可能性。https://t.co/fwmN6V2zAO
RT @LioCavic: Le #coronavirus de #Wuhan partagerait un ancêtre commun avec les coronavirus du #SRAS. Cet un ancêtre ressemble à un coronavi…
Le #coronavirus de #Wuhan partagerait un ancêtre commun avec les coronavirus du #SRAS. Cet un ancêtre ressemble à un coronavirus de #chauvesouris, HK9-1. https://t.co/icJ4GZyhHU
The transmission of #WuhanCoV across species/humans is similar to SARS-CoV and MERS-CoV, although it is not clear yet and could be a different mechanism. https://t.co/Qw4cEZgfCs
This note published in the journal SCIENCE #CHINA Life Sciences explain the #Wuhan 2019-nCoV #Coronavirus origen. ➖ Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission. https://t.co/CaEYqPELwY https://t.co/jgUlTQTjZC
"Transmisión de especies cruzadas": lo que dicen algunos papers recientes sobre el nuevo Coronavirus. Dos estudios señalan que el nuevo #Coronavirus se generó en #Murciélagos, llegando a los humanos a través de #Serpientes: https://t.co/jYd722VyNL https://t.co/EsIMYJ2HNh https://t.co/g5KIg7mAzj
@hoaxeye @TitoElBandito https://t.co/8OUipt0xjm
RT @Laurie_Garrett: Virology of #nCoV2019 from a big Chinese team finds the new virus binds to human lung cells using the same molecular me…
あとで読む #新型コロナウイルス [https://t.co/zmIPVk6IXT] Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission https://t.co/slL5rxr1xD
RT @onlyyoontv: “The RBD domain of the Wuhan CoV S-protein supports strong interaction with human ACE2 molecules despite its sequence diver…
From Weibo and 'Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission' #nCoV2019 #nCoV https://t.co/sLeKYgMEpa
RT @TheMenacheryLab: So I'd be cautious with this interpretation. The paper (https://t.co/Q4SlezUNAm) models the structural interactions be…
RT @TheMenacheryLab: So I'd be cautious with this interpretation. The paper (https://t.co/Q4SlezUNAm) models the structural interactions be…
RT @drkristenkc: “Wuhan CoV poses a significant public health risk for human transmission via the S-protein–ACE2 binding pathway” ...risk o…
RT @PDChina: Chinese scientists found that the receptor-binding pathway of #nCoV2019 and #SARS are similar from a study of the virus’ evolu…
RT @Laurie_Garrett: Virology of #nCoV2019 from a big Chinese team finds the new virus binds to human lung cells using the same molecular me…
RT @onlyyoontv: “The RBD domain of the Wuhan CoV S-protein supports strong interaction with human ACE2 molecules despite its sequence diver…
RT @PDChinaScience: Chinese scientists found that the receptor-binding pathway of #nCoV2019 and #SARS are similar from a study of the virus…
RT @TheMenacheryLab: So I'd be cautious with this interpretation. The paper (https://t.co/Q4SlezUNAm) models the structural interactions be…
RT @Laurie_Garrett: Virology of #nCoV2019 from a big Chinese team finds the new virus binds to human lung cells using the same molecular me…
RT @TheMenacheryLab: So I'd be cautious with this interpretation. The paper (https://t.co/Q4SlezUNAm) models the structural interactions be…
RT @PDChina: Chinese scientists found that the receptor-binding pathway of #nCoV2019 and #SARS are similar from a study of the virus’ evolu…
RT @PDChina: Chinese scientists found that the receptor-binding pathway of #nCoV2019 and #SARS are similar from a study of the virus’ evolu…
RT @TheMenacheryLab: So I'd be cautious with this interpretation. The paper (https://t.co/Q4SlezUNAm) models the structural interactions be…
RT @PDChina: Chinese scientists found that the receptor-binding pathway of #nCoV2019 and #SARS are similar from a study of the virus’ evolu…
RT @TheMenacheryLab: So I'd be cautious with this interpretation. The paper (https://t.co/Q4SlezUNAm) models the structural interactions be…
RT @PDChinaScience: Chinese scientists found that the receptor-binding pathway of #nCoV2019 and #SARS are similar from a study of the virus…
RT @PDChina: Chinese scientists found that the receptor-binding pathway of #nCoV2019 and #SARS are similar from a study of the virus’ evolu…
RT @PDChina: Chinese scientists found that the receptor-binding pathway of #nCoV2019 and #SARS are similar from a study of the virus’ evolu…
RT @PDChina: Chinese scientists found that the receptor-binding pathway of #nCoV2019 and #SARS are similar from a study of the virus’ evolu…
RT @PDChina: Chinese scientists found that the receptor-binding pathway of #nCoV2019 and #SARS are similar from a study of the virus’ evolu…
RT @PDChina: Chinese scientists found that the receptor-binding pathway of #nCoV2019 and #SARS are similar from a study of the virus’ evolu…
RT @PDChinaScience: Chinese scientists found that the receptor-binding pathway of #nCoV2019 and #SARS are similar from a study of the virus…
RT @PDChina: Chinese scientists found that the receptor-binding pathway of #nCoV2019 and #SARS are similar from a study of the virus’ evolu…
RT @PDChina: Chinese scientists found that the receptor-binding pathway of #nCoV2019 and #SARS are similar from a study of the virus’ evolu…
RT @PDChina: Chinese scientists found that the receptor-binding pathway of #nCoV2019 and #SARS are similar from a study of the virus’ evolu…
https://t.co/QEsuT1S4GZ Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission
RT @deng_ziqi: "....Wuhan CoV poses a significant public health risk for human transmission via the S-protein–ACE2 binding pathway..." Evol…
Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission https://t.co/vFFLFk5qcV
RT @bitex2047: 21日,中科院上海巴斯德研究所、军事医学研究院国家应急防控药物工程技术研究中心和中科院分子植物中心合成生物学重点实验室合作在线发表“Evolution of the novel coronavirus from the ongoing Wuhan…
"....Wuhan CoV poses a significant public health risk for human transmission via the S-protein–ACE2 binding pathway..." Evolution of the novel coronavirus from the ongoing Wuhan outbreak an... - #wuhanvirus #WuhanCoronavirus https://t.co/DJ5hUsfB8P https://t.co/fI8XONYoiH
Pura ciencia bbs 武汉新型冠状病毒的进化来源和传染人的分子作用通路Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission https://t.co/Ys3D0FJmru
21日,中科院上海巴斯德研究所、军事医学研究院国家应急防控药物工程技术研究中心和中科院分子植物中心合成生物学重点实验室合作在线发表“Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission” #对人感染力很强 https://t.co/jSIouddvkS
Evolution of the novel coronavirus from the ongoing Wuhan outbreak an... - https://t.co/KZOaAhy6g8