Because IV iron can induce hypophosphatemia, 2 RCTs compared the effects of iron isomaltoside (AKA ferric derisomaltose) vs ferric carboxymaltose and report the former resulted in lower hypophosphatemia over 35 days https://t.co/UKyHy81oq1 #VisualAbstract
Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia: Two Randomized Clinical Trials.
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Feb 2020 – Oct 2025Where it's discussed
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X / Twitter63 posts
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AI synopsis
What people are saying
Numerous discussions reference the clinical significance of the research, particularly pointing out the lower incidence of hypophosphatemia with iron isomaltoside. Phrases like 'this paper shows almost 75% incidence with ferric carboxymaltose' highlight the urgency and importance of these findings. The tone is both informative and urgent, suggesting that the findings could lead to a shift in clinical practices surrounding iron treatments.
The majority of posts express strong support for the findings of the study, highlighting the advantages of iron isomaltoside.
There is a high level of curiosity and relevance as many participants actively engage with the study's implications for treatment.
Users show deep engagement by discussing specific data points, safety concerns, and biochemical mechanisms involved in hypophosphatemia.
Contributors perceive significant potential implications for clinical practice, as evidenced by discussions around patient experiences and treatment choices.
Abstract in brief
- The study compares the effects of two intravenous iron formulations, iron isomaltoside and ferric carboxymaltose, on hypophosphatemia in patients with iron-deficiency anemia.
- A total of 245 patients were enrolled in two clinical trials, with serum phosphate and other related biomarkers measured at multiple points during the study.
- Results showed that the incidence of hypophosphatemia was significantly lower in patients receiving iron isomaltoside compared to those receiving ferric carboxymaltose.
Top posts
Most liked on X and BlueskyEffects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia: Two Randomized Clinical Trials | Clinical Pharmacy and Pharmacology | @JAMA_current https://t.co/VWdzlgRUUj
En este estudio, 2 dosis de 750 mg de hierro #carboximaltosa separadas por una semana produjeron un 11% de hipofosfatemia grave (<1 mg/dl). Ojo al fósforo si dosis repetidas o síntomas: "Doctor, me pone hierro pero me canso más, no puedo con las piernas". https://t.co/iwfxfjuSAP https://t.co/YnyrQoFwUG
Myles Wolf and colleagues in @JAMA_current Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia: 2 RCTs https://t.co/1Dx0Gl4HTE
@kidney_boy Great case @TheSkeletonKG! Have had a few cases including severe hypophos with osteomalacia after regular ferric carboxymaltose infusions over yrs. Not a high incidence with other iron preparations.This paper shows almost 75% incidence with ferr carbmalt. https://t.co/7plW0WAZUz
Great job #nephtwitter! Yes, Hypophosphatemia is the answer. ✨ Ferric carboxymaltose causes increase in FGF-23 levels ➡️ phosphaturic hormone leading to kidney phos excretion ✨ @TheSkeletonKG case 9 addresses this perfectly! https://t.co/9EEoEKvUU5 https://t.co/eg3dJtZvrK https://t.co/3YUrUY2pAp
All mentions
Comparing Iron Formulations: Insights on Hypophosphatemia
Eisenmangel gehört für die meisten Ärzte weltweit zum Tagesgeschäft. In dieser Podcastfolge analysieren wir Forschungsergebnisse zu intravenösen Eisenformulierungen und deren Auswirkungen auf Hypophosphatämie bei…
Comparative Risks of Iron Therapy in Iron Deficiency Anemia
Bei Eisenmangel wird häufig eine Behandlung mit Eisentabletten oder Eiseninfusionen durchgeführt. Es sind jedoch einige wichtige Punkte zu beachten, da die Infusionen schwerwiegende Probleme wie Phosphatverlust und…
Current Standards for Renal Anaemia Treatment by Prof. Iain Macdougall
https://t.co/Kny5F01WSK
RT @PA_Maday: Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia https://t.co/VqBhwMXkCV…
Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia https://t.co/66Jf00Gyxr
@ph_ttkt https://t.co/zpfqIyzMcL
RT @pinacol: 【RCT】経口鉄剤1ヶ月以上へ忍容性がない又は不応の鉄欠乏性貧血患者へのイソマルトシド鉄静注は、カルボキシマルトース鉄注と比較して、低リン血症の発生率を減少させた。 https://t.co/nv8YjJbRmY
RT @pinacol: 【RCT】経口鉄剤1ヶ月以上へ忍容性がない又は不応の鉄欠乏性貧血患者へのイソマルトシド鉄静注は、カルボキシマルトース鉄注と比較して、低リン血症の発生率を減少させた。 https://t.co/nv8YjJbRmY
RT @salvadorpayan: En este estudio, 2 dosis de 750 mg de hierro #carboximaltosa separadas por una semana produjeron un 11% de hipofosfatemi…
RT @salvadorpayan: En este estudio, 2 dosis de 750 mg de hierro #carboximaltosa separadas por una semana produjeron un 11% de hipofosfatemi…
RT @salvadorpayan: En este estudio, 2 dosis de 750 mg de hierro #carboximaltosa separadas por una semana produjeron un 11% de hipofosfatemi…
RT @salvadorpayan: En este estudio, 2 dosis de 750 mg de hierro #carboximaltosa separadas por una semana produjeron un 11% de hipofosfatemi…
En este estudio, 2 dosis de 750 mg de hierro #carboximaltosa separadas por una semana produjeron un 11% de hipofosfatemia grave (<1 mg/dl). Ojo al fósforo si dosis repetidas o síntomas: "Doctor, me pone hierro pero me canso más, no puedo con las piernas". https://t.co/iwfxfjuSAP https://t.co/YnyrQoFwUG
@PromiseAlharbi https://t.co/p5nhBoncvX
リンの低下が少ないかも? Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia Two Randomized Clinical Trials https://t.co/y0HOZAmzB9
RT @luyimin2009: @drkeithsiau Great summary! To add: ferric carboxymaltose could acutely elevate iFGF23 to induce hypophosphatemia. https:/…
RT @luyimin2009: @drkeithsiau Great summary! To add: ferric carboxymaltose could acutely elevate iFGF23 to induce hypophosphatemia. https:/…
RT @luyimin2009: @drkeithsiau Great summary! To add: ferric carboxymaltose could acutely elevate iFGF23 to induce hypophosphatemia. https:/…
@drkeithsiau Great summary! To add: ferric carboxymaltose could acutely elevate iFGF23 to induce hypophosphatemia. https://t.co/YMd5Mdk6cK
Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia https://t.co/VqBhwMXkCV https://t.co/jrCGPzoD8x
RT @NWiegley: Great job #nephtwitter! Yes, Hypophosphatemia is the answer. ✨ Ferric carboxymaltose causes increase in FGF-23 levels ➡️ pho…
RT @NWiegley: Great job #nephtwitter! Yes, Hypophosphatemia is the answer. ✨ Ferric carboxymaltose causes increase in FGF-23 levels ➡️ pho…
Great job #nephtwitter! Yes, Hypophosphatemia is the answer. ✨ Ferric carboxymaltose causes increase in FGF-23 levels ➡️ phosphaturic hormone leading to kidney phos excretion ✨ @TheSkeletonKG case 9 addresses this perfectly! https://t.co/9EEoEKvUU5 https://t.co/eg3dJtZvrK https://t.co/3YUrUY2pAp
Wolf et al. No differences in efficacy between #ferinject and #monofer, but there are differences in #hypophosphataemia https://t.co/SuJcQCksay
@hswapnil Did they look at serum phosphorus? Carboxymaltose has much higher risk for hypophosphatemia. #Kidneywk https://t.co/7plW0WAZUz
RT @VijayanMD: @kidney_boy Great case @TheSkeletonKG! Have had a few cases including severe hypophos with osteomalacia after regular ferric…
RT @VijayanMD: @kidney_boy Great case @TheSkeletonKG! Have had a few cases including severe hypophos with osteomalacia after regular ferric…
RT @VijayanMD: @kidney_boy Great case @TheSkeletonKG! Have had a few cases including severe hypophos with osteomalacia after regular ferric…
@kidney_boy Great case @TheSkeletonKG! Have had a few cases including severe hypophos with osteomalacia after regular ferric carboxymaltose infusions over yrs. Not a high incidence with other iron preparations.This paper shows almost 75% incidence with ferr carbmalt. https://t.co/7plW0WAZUz
静脈注射での鉄剤補充による、低リン血症の比較 https://t.co/YR3vTTcOPc
RT @DukeKidney: Myles Wolf and colleagues in @JAMA_current Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in I…
RT @DukeKidney: Myles Wolf and colleagues in @JAMA_current Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in I…
Myles Wolf and colleagues in @JAMA_current Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia: 2 RCTs https://t.co/1Dx0Gl4HTE
RT @JAMA_current: Because IV iron can induce hypophosphatemia, 2 RCTs compared the effects of iron isomaltoside (AKA ferric derisomaltose)…
Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia: Two Randomized Clinical Trials. https://t.co/WH3pXJedHa
RT @GIdietitian: Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia: Two Randomized Clinic…
RT @GIdietitian: Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia: Two Randomized Clinic…
RT @JAMA_current: Because IV iron can induce hypophosphatemia, 2 RCTs compared the effects of iron isomaltoside (AKA ferric derisomaltose)…
Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia https://t.co/atphhlM8m8
RT @JAMA_current: Because IV iron can induce hypophosphatemia, 2 RCTs compared the effects of iron isomaltoside (AKA ferric derisomaltose)…
RT @GIdietitian: Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia: Two Randomized Clinic…
Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia. https://t.co/t8Fwbn8dZd
RT @GIdietitian: Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia: Two Randomized Clinic…
RT @GIdietitian: Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia: Two Randomized Clinic…
RT @GIdietitian: Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia: Two Randomized Clinic…
RT @JAMA_current: Because IV iron can induce hypophosphatemia, 2 RCTs compared the effects of iron isomaltoside (AKA ferric derisomaltose)…
RT @JAMA_current: Because IV iron can induce hypophosphatemia, 2 RCTs compared the effects of iron isomaltoside (AKA ferric derisomaltose)…
RT @JAMA_current: Because IV iron can induce hypophosphatemia, 2 RCTs compared the effects of iron isomaltoside (AKA ferric derisomaltose)…
RT @GIdietitian: Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia: Two Randomized Clinic…
RT @JAMA_current: Because IV iron can induce hypophosphatemia, 2 RCTs compared the effects of iron isomaltoside (AKA ferric derisomaltose)…
RT @JAMA_current: Because IV iron can induce hypophosphatemia, 2 RCTs compared the effects of iron isomaltoside (AKA ferric derisomaltose)…
RT @JAMA_current: Because IV iron can induce hypophosphatemia, 2 RCTs compared the effects of iron isomaltoside (AKA ferric derisomaltose)…
RT @JAMA_current: Because IV iron can induce hypophosphatemia, 2 RCTs compared the effects of iron isomaltoside (AKA ferric derisomaltose)…
RT @JAMA_current: Because IV iron can induce hypophosphatemia, 2 RCTs compared the effects of iron isomaltoside (AKA ferric derisomaltose)…
RT @JAMA_current: Because IV iron can induce hypophosphatemia, 2 RCTs compared the effects of iron isomaltoside (AKA ferric derisomaltose)…
Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia: Two Randomized Clinical Trials | Clinical Pharmacy and Pharmacology | @JAMA_current https://t.co/VWdzlgRUUj
RT @JAMA_current: Because IV iron can induce hypophosphatemia, 2 RCTs compared the effects of iron isomaltoside (AKA ferric derisomaltose)…
RT @JAMA_current: Because IV iron can induce hypophosphatemia, 2 RCTs compared the effects of iron isomaltoside (AKA ferric derisomaltose)…
RT @JAMA_current: Because IV iron can induce hypophosphatemia, 2 RCTs compared the effects of iron isomaltoside (AKA ferric derisomaltose)…
RT @JAMA_current: Because IV iron can induce hypophosphatemia, 2 RCTs compared the effects of iron isomaltoside (AKA ferric derisomaltose)…
RT @JAMA_current: Because IV iron can induce hypophosphatemia, 2 RCTs compared the effects of iron isomaltoside (AKA ferric derisomaltose)…
RT @JAMA_current: Because IV iron can induce hypophosphatemia, 2 RCTs compared the effects of iron isomaltoside (AKA ferric derisomaltose)…
Because IV iron can induce hypophosphatemia, 2 RCTs compared the effects of iron isomaltoside (AKA ferric derisomaltose) vs ferric carboxymaltose and report the former resulted in lower hypophosphatemia over 35 days https://t.co/UKyHy81oq1 #VisualAbstract
Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia https://t.co/de2kqv9uEV
From our chief. Congrats on your exciting discovery! https://t.co/OhWoSoix5u