Adv Ther March 2020 PMID 32016788

Efficacy and Safety of Intravitreal Aflibercept Treat-and-Extend Regimens in Exudative Age-Related Macular Degeneration: 52- and 96-Week Findings from ALTAIR : A Randomized Controlled Trial.

Masahito Ohji, Kanji Takahashi, Annabelle A Okada, Masato Kobayashi, Yoshimi Matsuda, Yasuhiro Terano

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Mentions

18
Peak: 9 in Feb 2020
across 3 sources since Feb 2020

Extended reach

13,387
potential audience

Total likes

19

Video views

2,792

Mentions per month

Feb 2020 – Sep 2024

Where it's discussed

  • X / Twitter15 posts
  • News2 articles
  • YouTube1 videos

AI synopsis

What people are saying

The overall tone reflects strong support and interest in the study's findings, with posts referencing specific elements like the comparable improvements in visual acuity and the potential for longer dosage intervals, supported by mentions of infographics, video summaries, and clinical trial details. The words and tone suggest a positive reception and recognition of the study's potential influence on treatment practices in ophthalmology.

AgreementModerate agreement

Most discussions emphasize the positive findings of the ALTAIR study, supporting the effectiveness and safety of the treatment regimen.

InterestHigh interest

Posts show high curiosity and enthusiasm about the study, with references to infographic summaries, video abstracts, and treatment comparisons.

EngagementModerate engagement

Participants reference detailed aspects like dosage intervals, safety profiles, and implications for treatment burden, indicating moderate active engagement.

ImpactModerate impact

The discussions highlight the significance of the research, suggesting impacts on treatment protocols and patient outcomes, especially with mentions of reduced treatment burden and inflammation.

Abstract in brief

  • The study shows that intravitreal injections of aflibercept using treat-and-extend regimens are effective and safe for patients with exudative age-related macular degeneration, improving vision and reducing retinal thickness over 52 and 96 weeks.
  • Patients in both the 2-week and 4-week adjustment groups experienced similar improvements in visual acuity and anatomical outcomes, with the treatment safe and well-tolerated.
  • The treatment involved regularly scheduled injections, with most patients maintaining intervals of 12 weeks or longer before subsequent doses, demonstrating the durability and safety of this approach over nearly two years.]

Top posts

Most liked on X and Bluesky
Ophthopedia
@ophthopedia · X

Ophthopedia Update: Infographic: Efficacy and safety of intravitreal aflibercept treat-and-extend regimens in exudative age-related macular degeneration: ALTAIR study https://t.co/JIdtFchFr6 #Ophthalmology #Eye #Ophthotwitter https://t.co/NGQocwgukf

Sep 19, 2024 · 4 likes · 3 shares · 2,539 followers View post →
SpeedyGonzalesi
@chaperonycon · X

#eylea has less anti drug antibodies than #beovu and less inflammation figures. Dosage interval could be comparable, as altair study suggests. https://t.co/HxriqzweIk https://t.co/NsFleaSlF0

Feb 8, 2020 · 2 likes · 2 shares · 70 followers View post →
KKESH Pharmacy
@KKESHPharmacy · X

RT @AdvancesTherapy: The results from the ALTAIR study have just been published - investigating the efficacy and safety of intravitreal #af…

Feb 16, 2020 · 2 shares · 1,540 followers View post →
Ophthalmology Ther
@Ophthal_Therapy · X

The results of the ALTAIR study were published in our sister journal Advances in Therapy. Read the full article #openaccess here: https://t.co/ax1u5fQpJ0 https://t.co/WYpLQ6wYEy

Feb 7, 2020 · 1,405 followers View post →
Advances in Therapy
@AdvancesTherapy · X

The published study can be found here: https://t.co/QkUvFfnaL4 #openaccess https://t.co/A0hdP6b4rl

Feb 7, 2020 · 1 share · 1,192 followers View post →
Advances in Therapy
@AdvancesTherapy · X

The results from the ALTAIR study have just been published - investigating the efficacy and safety of intravitreal #aflibercept treat-and-extend regimens in exudative age-related macular degeneration: https://t.co/EN6utdzml5 #ophthalmology https://t.co/5WcAz2JFqN

Feb 4, 2020 · 2 shares · 1,192 followers View post →

All mentions

Dr G.Sudha
@g_ophthalmology · X

RT @ophthopedia: Ophthopedia Update: Infographic: Efficacy and safety of intravitreal aflibercept treat-and-extend regimens in exudative ag…

Sep 20, 2024 · 3 shares · 160 followers View post →
Dr. Alsayed Shaaban
@DrAlsayedShaab1 · X

RT @ophthopedia: Ophthopedia Update: Infographic: Efficacy and safety of intravitreal aflibercept treat-and-extend regimens in exudative ag…

Sep 20, 2024 · 3 shares · 69 followers View post →
DrAyman1982
@DrAyman1982 · X

RT @ophthopedia: Ophthopedia Update: Infographic: Efficacy and safety of intravitreal aflibercept treat-and-extend regimens in exudative ag…

Sep 20, 2024 · 3 shares · 18 followers View post →
Ophthopedia
@ophthopedia · X

Ophthopedia Update: Infographic: Efficacy and safety of intravitreal aflibercept treat-and-extend regimens in exudative age-related macular degeneration: ALTAIR study https://t.co/JIdtFchFr6 #Ophthalmology #Eye #Ophthotwitter https://t.co/NGQocwgukf

Sep 19, 2024 · 4 likes · 3 shares · 2,539 followers View post →
AdisJournals
@AdisJournals · X

We've just published a video abstract to accompany the ALTAIR study in @AdvancesTherapy. The 4 minute video can be watched here: https://t.co/5pFaUxozvt #openaccess #videoabstract #digital https://t.co/A1F2JTjUwj

Nov 10, 2020 · 577 followers View post →
Ethical GmbH
@Ethicalgmbh · X

Efficacy and Safety of Intravitreal Aflibercept Treat-and-Extend Regimens in Exudative Age-Related Macular Degeneration: 52- and 96-Week Findings from ALTAIR https://t.co/xoVyJHeS4L #clinicalresearch #clinicaltrials #endpointadjudication #electronichealthrecords #clinicalstudy https://t.co/iaIowd3LIh

Mar 6, 2020 · 487 followers View post →
KKESH Pharmacy
@KKESHPharmacy · X

RT @AdvancesTherapy: The results from the ALTAIR study have just been published - investigating the efficacy and safety of intravitreal #af…

Feb 16, 2020 · 2 shares · 1,540 followers View post →
M.
@tomorrowdaworld · X

RT @chaperonycon: #eylea has less anti drug antibodies than #beovu and less inflammation figures. Dosage interval could be comparable, as a…

Feb 9, 2020 · 2 shares · 252 followers View post →
Miljenko Zuanic
@Miljenkoz · X

RT @chaperonycon: #eylea has less anti drug antibodies than #beovu and less inflammation figures. Dosage interval could be comparable, as a…

Feb 9, 2020 · 2 shares · 380 followers View post →
SpeedyGonzalesi
@chaperonycon · X

#eylea has less anti drug antibodies than #beovu and less inflammation figures. Dosage interval could be comparable, as altair study suggests. https://t.co/HxriqzweIk https://t.co/NsFleaSlF0

Feb 8, 2020 · 2 likes · 2 shares · 70 followers View post →
SpeedyGonzalesi
@chaperonycon · X

#eylea 12 week dosage interval possible for more than 50% of patients. #Novartis #beovu apparently not alone in the leading position concerning treatment burden. #wetamd https://t.co/HxriqzweIk

Feb 8, 2020 · 70 followers View post →
Ophthalmology Ther
@Ophthal_Therapy · X

The results of the ALTAIR study were published in our sister journal Advances in Therapy. Read the full article #openaccess here: https://t.co/ax1u5fQpJ0 https://t.co/WYpLQ6wYEy

Feb 7, 2020 · 1,405 followers View post →
AdisJournals
@AdisJournals · X

RT @AdvancesTherapy: The published study can be found here: https://t.co/QkUvFfnaL4 #openaccess https://t.co/A0hdP6b4rl

Feb 7, 2020 · 1 share · 577 followers View post →
Advances in Therapy
@AdvancesTherapy · X

The published study can be found here: https://t.co/QkUvFfnaL4 #openaccess https://t.co/A0hdP6b4rl

Feb 7, 2020 · 1 share · 1,192 followers View post →
Advances in Therapy
@AdvancesTherapy · X

The results from the ALTAIR study have just been published - investigating the efficacy and safety of intravitreal #aflibercept treat-and-extend regimens in exudative age-related macular degeneration: https://t.co/EN6utdzml5 #ophthalmology https://t.co/5WcAz2JFqN

Feb 4, 2020 · 2 shares · 1,192 followers View post →
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