Nat Microbiol April 2020 PMID 32094589

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses.

Michael Letko, Andrea Marzi, Vincent Munster

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Mentions

119

Peak: 13 in Feb 2020

across 5 sources since Feb 2020

Extended reach

91,029

potential audience

Total likes

Video views

1,947

Mentions per month

Feb 2020 – Oct 2024

Where it's discussed

News68 articles
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Blogs8 articles
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YouTube2 videos

AI synopsis

What people are saying

Overall, the discussions demonstrate a balanced appreciation of the article’s scientific value, with examples like referencing detailed studies and noting how understanding receptor usage could guide surveillance. Words such as 'good article' and mentions of 'significant insights' convey respect and acknowledgment of its importance, indicating a moderate level of interest and impact.

AgreementModerate agreement

Many posters acknowledge the significance of the study, with mentions of its relevance to SARS-CoV-2 research and references to prior work, indicating general support.

InterestModerate interest

Discussions reflect moderate interest, as posters express curiosity about the mechanisms and implications, without highly emotional or enthusiastic language.

EngagementModerate engagement

Comments include referencing specific researchers and methods, showing some depth of engagement with the scientific content.

ImpactModerate impact

Posts highlight the potential influence on understanding viral entry and surveillance efforts, suggesting perceived scientific and public health impact.

Abstract in brief

Over the last 20 years, several coronaviruses have jumped from animals to humans, leading to severe respiratory diseases, with limited tools for testing their infection capabilities.
A new method has been developed to quickly screen lineage B betacoronaviruses, like SARS-CoV and SARS-CoV-2, for their ability to infect human cells and use different receptors.
The study reveals that the way host cells process these viruses plays a crucial role in their entry, showing that overcoming this barrier allows some viruses to infect human cells through an unidentified receptor, and confirms that human ACE2 is the receptor for SARS-CoV-2.

Read the full abstract

All mentions

Understanding SARS-CoV-2: Key Questions Answered

This video addresses the most frequently asked questions about the SARS-CoV-2 coronavirus. Topics include its structure, symptoms of COVID-19, prevention strategies, and current treatment options, as well as its origin…

Serra Ozari (Alumni) · Mar 16, 2020 1,910 views

Zoonotic Bat Coronaviruses: Addressing Infection Barriers with Trypsin Treatment

This video explores how specific bat coronaviruses can infect humans, highlighting research on trypsin treatment to overcome infection barriers. Key findings suggest that both receptor binding and spike protein cleavage…

Reyna Arteaga · Sep 15, 2020 38 views

Chris Lancashire

@ChrisLancashir3 · X

RT @Amy31129057: Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B beta coronaviruses (February 24,…

Oct 10, 2024 · 2 shares · 3,366 followers View post →

꧁•⊹ ʙɪɢ ʀɪɢ

@B1gR1gBarb1e · X

RT @virologyanon: @quay_dr https://t.co/iNuzMQjCEc *Munster

Apr 26, 2024 · 4 shares · 1,835 followers View post →

Tony Macaroni (the original)

@TonyMac24628499 · X

RT @virologyanon: @quay_dr https://t.co/iNuzMQjCEc *Munster

Apr 26, 2024 · 4 shares · 512 followers View post →

GrinerATodd

@supertodd1 · X

RT @virologyanon: @quay_dr https://t.co/iNuzMQjCEc *Munster

Apr 18, 2024 · 4 shares · 1,565 followers View post →

Austere Religious Scholar &Patriot Encourager

@PossDoug · X

RT @virologyanon: @quay_dr https://t.co/iNuzMQjCEc *Munster

Apr 18, 2024 · 4 shares · 8,915 followers View post →

Fredy13

@Goofygrandpa · X

@53v3n0fn1n3 I think it is this paper https://t.co/LZQhhr7rFB

Apr 18, 2024 · 2 likes · 421 followers View post →

Anonymous Virologist PhD

@virologyanon · X

@quay_dr https://t.co/iNuzMQjCEc *Munster

Apr 17, 2024 · 19 likes · 4 shares · 1,742 followers View post →

Project Wuhan Engineering

@pcfurin · X

@BillyBostickson @Florin_Uncovers @franciscodeasis @MonaRahalkar @VBruttel @tony_vandongen @EcoHealthNYC @PeterDaszak 'Chimera' could refer to just the spike protein in this case. Guess that makes sense. E.g. what Letko, Marzi and Munster did in their 2020 Nature Microbiology paper: https://t.co/KdsYfRrNwE https://t.co/hp5kjkp8pN

Jan 19, 2024 · 1 like · 69 followers View post →

bubba’s lmn chop shop

@LmBubba · X

RT @Amy31129057: Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B beta coronaviruses (February 24,…

Sep 25, 2023 · 2 shares · 1,940 followers View post →

QuestionIt

@Amy31129057 · X

Sep 24, 2023 · 3 likes · 2 shares · 9,416 followers View post →

QuestionIt

@Amy31129057 · X

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B beta coronaviruses (February 24, 2020) Do you see it yet @RandPaul @RobertKennedyJr @SenRonJohnson https://t.co/TDUPkfW1yU https://t.co/SOqJUATZMr https://t.co/rWr7WtPSNm

Sep 24, 2023 · 9,416 followers View post →

Jim Haslam

@jhas5 · X

@FViromics Dr Letko, why did you discuss the FCS in SARS2 with journalists? https://t.co/2wVARvW06m But your paper with Dr Munster ignore it? https://t.co/v8oqg4m4vh

Jun 30, 2023 · 1 like · 3,698 followers View post →

bioRxiv Published

@biorxiv_pubd · X

Functional assessment of cell entry and receptor usage for lineage B ?-coronaviruses, including 2019-nCoV published as: https://t.co/dcFg3nBaDO @NatureMicrobiol #biorxiv

Aug 22, 2022 · 2,905 followers View post →

BatOneHealth

@BatOneHealth · X

Modelamiento y predicción: necesitamos integración de datos desde campo, secuencias genéticas, hasta ensayos funcionales de la capacidad de diferentes virus de infectar células humanas. Esto ayudaría a priorizar planes de vigilancia epidemiológica. https://t.co/HwLeOK2iga

Nov 26, 2021 · 1,064 followers View post →

BatOneHealth

@BatOneHealth · X

…Ces prédictions peuvent être utilisées pour prioriser les efforts de surveillance sur le terrain. https://t.co/HwLeOK2iga

Nov 24, 2021 · 1,064 followers View post →

Tyler Starr

@tylernstarr · X

RT @BatOneHealth: Development of computational and wet lab pipelines to translate sequence information from the field into assessments of a…

Nov 24, 2021 · 1 share · 2,879 followers View post →

BatOneHealth

@BatOneHealth · X

Development of computational and wet lab pipelines to translate sequence information from the field into assessments of a virus’s ability to infect human hosts could help to prioritize surveillance efforts https://t.co/HwLeOK2iga

Nov 23, 2021 · 1 like · 1 share · 1,064 followers View post →

Billy Bostickson

@BillyBostickson · X

Jun 16, 2021 · 1 like · 18,485 followers View post →

FDS

@fds71644083 · X

Aug 15, 2020 · 2 likes · 709 followers View post →

Eclecticity

@twistopherrobin · X

So here's 1 example of a "good" article. (1) It's from NIH virologists (2) It's in a good pub: Nature Microbiology "Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses" by Michael Letko, et al: https://t.co/0w2FaGy1zw

Mar 31, 2020 · 3,418 followers View post →

CRISP_SCIENCE

@ScienceCrisp · X

野生動物からヒトへ感染しそうなコロナウイルスを予測する Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betaCoV. Letko M et al. Nat Microbiol 2020-02-24. https://t.co/r7m0bTsmFc crisp_bio 2020-03-11 https://t.co/y6DD6Wan2o

Mar 10, 2020 · 1,920 followers View post →

dr jiggly nubbins

@jigglynubbins · X

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses | Nature Microbiology https://t.co/y7GgnIMtNo

Mar 5, 2020 · 1,901 followers View post →

Ciekawość.Nauka i Natura

@nauka_natura · X

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses | Nature Microbiology https://t.co/TEXhhZd5q9

Mar 2, 2020 · 1 like · 1,237 followers View post →

kai

@kai958531911 · X

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses | Nature Microbiology https://t.co/IKCUpC952v

Feb 28, 2020 · 263 followers View post →

今と未来を生きるための気付きとヒント！

@DreamStarAngel3 · X

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses | Nature Microbiology https://t.co/QHHpyjcVim

Feb 28, 2020 · 1,416 followers View post →

the paper link

@the_paper_link · X

Trend up+44: *Letko M* et al (Nat Microbiol) __Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses__ https://t.co/W0o7pmtxTp

Feb 27, 2020 · 136 followers View post →

the paper link

@the_paper_link · X

Trend new: *Letko M* et al (Nat Microbiol) __Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses__ https://t.co/W0o7pmtxTp

Feb 26, 2020 · 136 followers View post →

Yuri Zurita

@zurita_yuri · X

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses. https://t.co/fj998xkhra - via Researcher (@ResearcherApp)

Feb 26, 2020 · 474 followers View post →

NFTdose

@PaperbirdsH · X

New article: Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses. https://t.co/HgBUYOaoPW #coronavirus #COVID19 #2019ncov

Feb 26, 2020 · 302 followers View post →

J.R.

@cellcaller3 · X

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses Via: nature https://t.co/teBiUIfjeu

Feb 25, 2020 · 320 followers View post →

Dr Kevin Purcell @kevinpurcell.bsky.social

@kevinpurcell · X

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses | Nature Microbiology https://t.co/l3QaAAVKxa

Feb 24, 2020 · 2 likes · 1,503 followers View post →

AgNCanada ⭈ Fighting for Truth & Justice CA/USA

@AGNCanada · X

#COVID2019 #COVIDー19 #WUHAN Silver Biotics #ProtectYourself https://t.co/Bmyy7EG5q2

Feb 24, 2020 · 2,758 followers View post →

kai

@kai958531911 · X

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses | Nature Microbiology https://t.co/IKCUpC952v

Feb 24, 2020 · 263 followers View post →

Lorena Abadía-Patiño Asesora en Microbiología

@AbadiaEn · X

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses https://t.co/Wbhp6KmTNO

Feb 24, 2020 · 217 followers View post →

micropapers

@micro_papers · X

NM/ Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses https://t.co/89YdIHcP8m

Feb 24, 2020 · 332 followers View post →

Joost Snijder

@joostsnijder · X

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses https://t.co/g5UJJclwdv

Feb 24, 2020 · 1,366 followers View post →

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Understanding SARS-CoV-2: Key Questions Answered

Zoonotic Bat Coronaviruses: Addressing Infection Barriers with Trypsin Treatment