The overall discussions reflect high agreement on the study's conclusion that pangolins are unlikely the direct source of SARS-CoV-2, exemplified by phrases like 'disproved pangolin theory' and 'research shows no direct link.' The tone is scientific and confident, emphasizing the importance of genomics and molecular evidence in tracing the virus's history, which demonstrates deep engagement and recognition of the study's impact on understanding COVID-19 origins.
AgreementStrong agreement
Most discussions emphasize that the research convincingly shows SARS-CoV-2 did not originate directly from pangolins, supporting consensus views in the scientific community.
InterestHigh interest
Discussions focus heavily on the origins of the virus, a highly relevant and engaging topic amid ongoing debates and research efforts.
EngagementHigh engagement
Posts include references to detailed analyses, molecular evidence, and scientific studies, showing deep engagement with the research methodology and conclusions.
ImpactHigh impact
The discussions underscore the significance of correctly identifying the virus's origins for public health, policy, and scientific understanding, indicating high impact.
Abstract in brief
The study analyzed 70 SARS-CoV-2 genomes from China and other regions, estimating that the most recent common ancestor existed around late November 2019, with the virus evolving at a rate of about 1.19 to 1.31 x 10^-3 substitutions per site per year.
Researchers examined genomic data from pangolins and bats, finding that a bat coronavirus (BetaCoV Yunnan RaTG13) was more similar to SARS-CoV-2 than pangolin samples, and noting that pangolins did not carry certain spike protein features linked to human infectivity.
A key finding was a unique peptide insertion (PRRA) in the human virus's spike protein, which might influence how the virus infects cells and spreads, but this insertion was absent in pangolin viruses, suggesting that SARS-CoV-2 did not directly originate from pangolins.
اگر گوگل کنید "Hubei lockdown"، تاریخ شروع قرنطینه رو ۲۳ ژانویه ۲۰۲۰ میاره. تا آن روز بیش از ۷ م. نفر از شهر #Wuhan خارج شده بودن (توییت کوتشده)؛ حکومت چین مرکز ویروس را هنوز قرنطینه نکرده بود. بررسی ژنوم ویروس، تاریخ پیدایش رو ۲۴ نوامبر ۲۰۱۹ نشون داده.
https://t.co/LJzQ5QR0Ci https://t.co/IsEd6Lrqxt
Mar 28, 2020 · 37 likes · 10 shares · 5,541 followersView post →
PL
Philippe Lemoine
@phl43 · X
By the way, not only is there no evidence that anyone even suspected the existence of SARS-CoV-2 until December, but genetic evidence, based on which it has been estimated that the virus originated in late November, also makes that overwhelmingly unlikely. https://t.co/FSUSfzYCK0
Nice study! The authors also identified "an unexpected furin cleavage site at the S1/S2 boundary of #SARSCoV2". Several groups have also noticed this furin site: chinaXiv:202002.00004; chinaXiv:202002.00062; Antivir Res 176:104742; JMV:10.1002/jmv.25731 @veeslerlab @DrEricDing https://t.co/NEC2g2T1QQ
Mar 10, 2020 · 11 likes · 5 shares · 1,765 followersView post →
PE
Plan International EU
@PlanEU · X
In this moment of crisis and uncertainty, it's important to support #children in processing their feelings and understanding the virus.
3/3. Everything well referenced! it is so great to find articles that summarize the overwhelming amount of information around us. REFERENCES cited here:
- https://t.co/I6rw7OJomz
- https://t.co/tls6m1vwdL
- https://t.co/1QrnDopfJK
- https://t.co/cE7gk2dRbo
This video demonstrates how to analyze the similarity between SARS-CoV-2 and bat coronaviruses using genome sequences and bioinformatics tools like BLASTN, along with bash commands for data filtering.
As most of us process our own feelings of anxiety, stress, and uncertainty during COVID-19, it's crucial to support children in understanding this virus. This video features our CEO answering children's questions about…
This video explores the origins of the SARS-CoV-2 coronavirus, focusing on its potential evolution from bats and the analysis of related genomes. Techniques like blastn and bash commands are used to examine viral…
This video explains why the current coronavirus SARS-CoV-2 is believed to originate from bats. Using blastn to compare sequences and exploring genomic similarities, it provides insights into the virus's evolutionary…
40/47 A molecular dating estimate based on the SARS-CoV-2 genomic sequences indicates an earlier origin, also concluding, “that the human SARS‐CoV‐2 virus, which is responsible for the current outbreak of COVID‐19, did not come directly from pangolins.” https://t.co/Ajmh77E0UP
RT @soheiil7: اگر گوگل کنید "Hubei lockdown"، تاریخ شروع قرنطینه رو ۲۳ ژانویه ۲۰۲۰ میاره. تا آن روز بیش از ۷ م. نفر از شهر #Wuhan خارج شده…
Nov 9, 2020 · 10 shares · 286 followersView post →
M
Marlon
@Mar_Sido · X
@dr_zissou Y'a toujours une question derrière.
De quand date ce nouveau virus ? https://t.co/P47cH8HTAv
Arrivée multiple / potentiel de réduction du R au Brésil ? https://t.co/znycYRXZPC
Diversité du virus, clade D614G, multiples introductions dans la population ? https://t.co/di1VBTFK8n
@dharmang_dmg @GordonGChang @FoxNews "she believes is not evidence" & is to claim something true without proof #China #Covid19 Genetic sequence shows the claim false! 96% of genome is shared with #coronavirus of horseshoe bats and possibly pangolins https://t.co/i0waIMUfxw
@BillyBostickson @jwordfish @luigi_warren @ydeigin @R_H_Ebright @PaulGodolphin @Real_Adam_B @TheSeeker268 @uacjess @AntGDuarte @BioObject @Daoyu15 @JJ2000426 @Nomdeplumi1 @_coltseavers @scottburke777 @still_a_nerd @jjcouey @Harvard2H @franciscodeasis @CarltheChippy @DefeatTheElites @ico_dna @nerdhaspower @RolandBakerIII @DrAntoniSerraT1 Re: "flawed logic of Rambaut's analysis which has since been debunked."
Really?
This is when consilience/replication is important in science:
https://t.co/xhOyxtFgJF
https://t.co/xzmyMx1biK
https://t.co/xMHvADHrOU
https://t.co/d5vmYzRIFE
https://t.co/7LjR3P7Av4
@chrismartenson @chrismartenson https://t.co/MxrkTlQBrN "Interestingly, the coronavirus carried by pangolins did not havethe RRAR motif. Therefore, we concluded that the human SARS‐CoV‐2 virus, whichis responsible for the recent outbreak of COVID‐19, did not come directly from pangolins."
@AnaDeCanha @JaSantaolalla Aunque me he equivocado en el tono, decir que se ha demostrado en varios trabajos que el virus tiene un origen natural y que especular con conspiracionismos no tiene sentido. Unos de ejemplos:
https://t.co/OtzVKQBMUF
https://t.co/b2RoNjGmx5
https://t.co/3xI5zROCie
@MikeMikkelsen10 @19Insomnia82 Nein, diese Daten sind ziemlich sicher: https://t.co/bNmlW9FYs4
Bei der aktuellen Ansteckungsfähigkeit sind bereits relativ kurz nach dem ersten Auftreten gehäuft Lungenentzündungen unklarer Herkunft aufgetreten. Wäre das Virus länger im Umlauf, wären die früher aufgefallen.
"Pangolin coronavirus samples were less similar to SARS‐CoV‐ 2 virus than to BetaCoV/bat/Yunnan/RaTG13/2013 virus & did not have RRAR motif. Therefore, SARS‐CoV‐2 virus, responsible for current outbreak of COVID‐19, did not come directly from pangolins" https://t.co/G7FOVtTMmU
@titanflux @rvolt24 @joshrogin @K_G_Andersen "Pangolin coronavirus samples were less similar to SARS‐CoV‐ 2 virus than to BetaCoV/bat/Yunnan/RaTG13/2013 virus & did not have RRAR motif. Therefore, SARS‐CoV‐2 virus, responsible for current outbreak of COVID‐19, did not come directly from pangolins" https://t.co/G7FOVtTMmU
@Bradley68441168 @JeremyKonyndyk @joshrogin @blakehounshell "Pangolin coronavirus samples were less similar to SARS‐CoV‐ 2 virus than to BetaCoV/bat/Yunnan/RaTG13/2013 virus & did not have RRAR motif. Therefore, SARS‐CoV‐2 virus, responsible for current outbreak of COVID‐19, did not come directly from pangolins" https://t.co/G7FOVtTMmU
@stgoldst @joshrogin @JeremyKonyndyk @blakehounshell "Pangolin coronavirus samples were less similar to SARS‐CoV‐ 2 virus than to BetaCoV/bat/Yunnan/RaTG13/2013 virus & did not have RRAR motif. Therefore, SARS‐CoV‐2 virus, responsible for current outbreak of COVID‐19, did not come directly from pangolins" https://t.co/G7FOVtTMmU
@SportyBecky @AlexKepfer @ColinCowherd I think that researchers are able to pretty conclusively study the evolutionary history of each strain (phylogenetic analysis). This stuff really confuses me but relates to how molecular dating can reveal its originating point, which is mid Nov.
https://t.co/Ee35z4yEdE
The "Scientist" publishing that paper about pangolin as a possible host for Sars-cov-2 is being paid by the Chinese CDC as a emeritus professor.
This REAL SCIENCE's research shows that pangolin IS NOT the intermediary host for the virus.
Stop CCP lies
Seriously... is no one reading the biology literature on SARS-CoV-2? It didn’t even exist as its own strain until the end of November.
https://t.co/00wEzUy9Iw https://t.co/36mRUwFe98 https://t.co/v82d3gZOQf
3/3. Todo muy bien referenciado. Que genial encontrar artículos que compilen la abrumadora cantidad de información alrededor. Referencias citadas en el artículo:
- https://t.co/xD4gJT9IEX
- https://t.co/4oxOYgO4GJ
- https://t.co/1QrnDopfJK
3/3. Everything well referenced! it is so great to find articles that summarize the overwhelming amount of information around us. REFERENCES cited here:
- https://t.co/I6rw7OJomz
- https://t.co/tls6m1vwdL
- https://t.co/1QrnDopfJK
- https://t.co/cE7gk2dRbo
Why not just retract? It's more than OK to get stuff wrong and try again. That's how science works. Literally none of the peer-reviewed literature (including phylogenetic analyses of the virus' MRCA) suggests that it even existed until the end of November
https://t.co/00wEzUy9Iw https://t.co/LxFED6gcmE
By the way, not only is there no evidence that anyone even suspected the existence of SARS-CoV-2 until December, but genetic evidence, based on which it has been estimated that the virus originated in late November, also makes that overwhelmingly unlikely. https://t.co/FSUSfzYCK0
@ydnadydnad There is still a grey region regarding SARS-CoV-2 origin. Studies tell that there is a possibility of it being a recombinant type. Also, its origin is very recent (late Nov. 2019 https://t.co/31VGP8hYaI). Unanswered is where and under which conditions did the recombination occur.
@t4_mg @Chulio92 @marietweetss @realDonaldTrump What’s the source? A molecular dating estimate placed the virus’ origin in November 2019. https://t.co/pPQvtCceVg. This is the same family of viruses that caused the 2002 outbreak in Guangdong and subsequently Hong Kong.
Genomic sequences Based on Bayesian time‐scaled phylogenetic analysis using the tip‐dating method, Estimated the time to the most recent common ancestor & evolutionary rate of SARS‐CoV‐2, ranged from 22 to 24 Nov-19
-Journal of Medical
RT @soheiil7: اگر گوگل کنید "Hubei lockdown"، تاریخ شروع قرنطینه رو ۲۳ ژانویه ۲۰۲۰ میاره. تا آن روز بیش از ۷ م. نفر از شهر #Wuhan خارج شده…
Mar 29, 2020 · 10 shares · 64 followersView post →
آ
آرام
@Beehava53 · X
RT @soheiil7: اگر گوگل کنید "Hubei lockdown"، تاریخ شروع قرنطینه رو ۲۳ ژانویه ۲۰۲۰ میاره. تا آن روز بیش از ۷ م. نفر از شهر #Wuhan خارج شده…
Mar 29, 2020 · 10 shares · 49 followersView post →
M
MehdiMMJ
@MehdiMMJ · X
RT @soheiil7: اگر گوگل کنید "Hubei lockdown"، تاریخ شروع قرنطینه رو ۲۳ ژانویه ۲۰۲۰ میاره. تا آن روز بیش از ۷ م. نفر از شهر #Wuhan خارج شده…
Mar 29, 2020 · 10 shares · 41,802 followersView post →
BK
Babak Khan
@BabakKhaaan · X
RT @soheiil7: اگر گوگل کنید "Hubei lockdown"، تاریخ شروع قرنطینه رو ۲۳ ژانویه ۲۰۲۰ میاره. تا آن روز بیش از ۷ م. نفر از شهر #Wuhan خارج شده…
Mar 28, 2020 · 10 shares · 1,577 followersView post →
S
sanam
@sanam18873207 · X
RT @soheiil7: اگر گوگل کنید "Hubei lockdown"، تاریخ شروع قرنطینه رو ۲۳ ژانویه ۲۰۲۰ میاره. تا آن روز بیش از ۷ م. نفر از شهر #Wuhan خارج شده…
Mar 28, 2020 · 10 shares · 545 followersView post →
NG
Nahid Ghani
@NahidGhani · X
RT @soheiil7: اگر گوگل کنید "Hubei lockdown"، تاریخ شروع قرنطینه رو ۲۳ ژانویه ۲۰۲۰ میاره. تا آن روز بیش از ۷ م. نفر از شهر #Wuhan خارج شده…
Mar 28, 2020 · 10 shares · 24,236 followersView post →
S
Soheil
@Soheilx · X
اگر گوگل کنید "Hubei lockdown"، تاریخ شروع قرنطینه رو ۲۳ ژانویه ۲۰۲۰ میاره. تا آن روز بیش از ۷ م. نفر از شهر #Wuhan خارج شده بودن (توییت کوتشده)؛ حکومت چین مرکز ویروس را هنوز قرنطینه نکرده بود. بررسی ژنوم ویروس، تاریخ پیدایش رو ۲۴ نوامبر ۲۰۱۹ نشون داده.
https://t.co/LJzQ5QR0Ci https://t.co/IsEd6Lrqxt
Mar 28, 2020 · 37 likes · 10 shares · 5,541 followersView post →
LT
Levent Ertur KocaSinanMahÜlküSAlanA Lüleburgaz TR
@ErturLevent · X
Evolutionary history, potential intermediate animal host, and cross‐species analyses of SARS‐CoV‐2 https://t.co/UvSQt4lgm0
@jchatterleyCNN @ErturLevent
Why is it said that #coronavirus (#SARSCoV2 ) is related to bats?
I explain that in this video:
https://t.co/6fezjmZkOg
Please move your conspiracy theories to the last option.
Warning: Technical video #bioinformatics
Some interesting pieces on the origins of the Coronavirus, though not entirely in agreement:
https://t.co/lGVnZrhMbU
https://t.co/mMsUwac2aq
https://t.co/e8E99Eb4G3
Mar 22, 2020 · 2 likes · 2,095 followersView post →
RT @ZhouLabUCR: Nice study! The authors also identified "an unexpected furin cleavage site at the S1/S2 boundary of #SARSCoV2". Several gro…
Mar 11, 2020 · 5 shares · 4,984 followersView post →
DO
Dr. Tran, D.O.
@Logicopa · X
RT @ZhouLabUCR: Nice study! The authors also identified "an unexpected furin cleavage site at the S1/S2 boundary of #SARSCoV2". Several gro…
Mar 11, 2020 · 5 shares · 433 followersView post →
ZL
Zhou Lab
@ZhouLabUCR · X
Nice study! The authors also identified "an unexpected furin cleavage site at the S1/S2 boundary of #SARSCoV2". Several groups have also noticed this furin site: chinaXiv:202002.00004; chinaXiv:202002.00062; Antivir Res 176:104742; JMV:10.1002/jmv.25731 @veeslerlab @DrEricDing https://t.co/NEC2g2T1QQ
Mar 10, 2020 · 11 likes · 5 shares · 1,765 followersView post →
BI
Bat Researcher - A.Prof. Aaron Irving
@BatResearch · X
Evolutionary history, potential intermediate animal host, and cross-species analyses of SARS-CoV-2. J Med Virol. 2020 Feb 27 https://t.co/I23SoHaWXG " Therefore, .. SARS-CoV-2 virus, which is responsible for the recent outbreak of COVID-19, did not come directly from pangolins. "
Mar 6, 2020 · 3 likes · 2,526 followersView post →
TL
the paper link
@the_paper_link · X
Trend new: *Li X* et al (J Med Virol) __Evolutionary history, potential intermediate animal host, and cross-species analyses of SARS-CoV-2__
https://t.co/vI8Xd4W3ae
Trend up+34: *Li X* et al (J Med Virol) __Evolutionary history, potential intermediate animal host, and cross-species analyses of SARS-CoV-2__
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Trend new: *Li X* et al (J Med Virol) __Evolutionary history, potential intermediate animal host, and cross-species analyses of SARS-CoV-2__
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Trend up+339: *Li X* et al (J Med Virol) __Evolutionary history, potential intermediate animal host, and cross-species analyses of SARS-CoV-2__
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Trend new: *Li X* et al (J Med Virol) __Evolutionary history, potential intermediate animal host, and cross-species analyses of SARS-CoV-2__
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