PubHawk
August 2020 PMID 32116073

The 'entourage effect' or 'hodge-podge hashish': the questionable rebranding, marketing, and expectations of cannabis polypharmacy.

Peter S Cogan

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Mentions

43
Peak: 18 in Mar 2020
across 4 sources since Mar 2020

Extended reach

199,289
potential audience

Total likes

6,836

Video views

154,794

Mentions per month

Mar 2020 – Apr 2025

Where it's discussed

  • X / Twitter34 posts
  • YouTube4 videos
  • News3 articles
  • Blogs2 articles

AI synopsis

What people are saying

Many comments, such as 'evidence for the widely touted entourage is thin' and references to unproven claims, demonstrate a critical stance towards the article’s findings. The tone is predominantly skeptical and dismissive, highlighting concerns over misleading marketing and the lack of solid scientific support, which reflects a collective disbelief in the purported benefits of cannabis polypharmacy promoted by commercial interests.

AgreementStrong disagreement

Most discussions strongly oppose the validity of the entourage effect, emphasizing the lack of scientific support and criticizing industry claims.

InterestModerate interest

There is moderate curiosity, with many users questioning the scientific basis and discussing the marketing tactics rather than engaging deeply with the research.

EngagementLow engagement

The tone is often dismissive or skeptical, with limited detailed discussion about the pharmacology; many posts simply condemn or criticize without exploring nuances.

ImpactLow impact

The collective sentiment suggests that these discussions see the article as raising critical issues that threaten industry credibility, thus perceiving it as having significant influence.

Abstract in brief

  • The concept of the cannabis entourage effect, first introduced in 1998, is often portrayed as a beneficial modulation of cannabis' therapeutic effects through the combination of various plant chemicals, but there is significant doubt about the scientific basis of these claims.
  • The article critically examines the literature supporting the entourage effect, highlighting that many claims are based on vague and unproven pharmacological activities, and points out potential adverse effects of some phytochemicals involved.
  • It questions the actual therapeutic value of the entourage effect, suggesting that its promotion is often driven by marketing rather than solid scientific evidence, leading to potential misuse and misrepresentation in the industry.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Amir Englund
@AmirEnglund · X

https://t.co/tVVCaCVfsv

Mar 4, 2020 · 4 likes · 4 shares · 2,586 followers View post →
Association of Cannabinoid Specialists
@cannaspecialist · X

Evidence for the widely touted Entourage is thin The ‘entourage effect’ or ‘hodge-podge hashish’: the questionable rebranding, marketing, and expectations of cannabis polypharmacy https://t.co/hvCkWTBPV4 #cannabis #medicine #patients #doctors @nejm @JAMA_current @CannabisJrnl https://t.co/4ZIA2RuHet

Jun 30, 2021 · 3 likes · 3 shares · 673 followers View post →
Graham Pechenik
@graham_pechenik · X

@MichaelHaichin @ManojDoss @sage_izzy And the entourage effect is certainly not without criticism: https://t.co/lw8OcWHO61 https://t.co/RM8s5CCpJ3

Jan 8, 2021 · 2 likes · 5,665 followers View post →
Greenthumb_one
@Greenthumb_one · X

The ‘entourage effect’ or ‘hodge-podge hashish’: the questionable rebranding, marketing, and expectations of cannabis polypharmacy [full-text pdf] https://t.co/lOKS8DOUsx #publichealthfirst https://t.co/zI81W5AI74 https://t.co/TralXpFlhr

Jun 30, 2021 · 1 like · 4,510 followers View post →
佐々伸也
@naoskihund · X

アントラージュ効果、臨床では十分な根拠が無いかそもそも効果がないと見込まれるってさ。 https://t.co/gh4thhWyUz https://t.co/QBXLV6y8U2 https://t.co/Og2X955bz2

Jan 8, 2021 · 1 like · 1 share · 4,118 followers View post →
Association of Cannabinoid Specialists
@cannaspecialist · X

Evidence for the widely touted Entourage is thin The ‘entourage effect’ or ‘hodge-podge hashish’: the questionable rebranding, marketing, and expectations of cannabis polypharmacy https://t.co/fte5bnqhff #cannabis #medicine #patients #doctors @nejm @JAMA_current @CannabisJrnl https://t.co/m9k1tVOwyf

Feb 3, 2021 · 1 like · 1 share · 673 followers View post →

All mentions

Xero Phyte -
@Xero_Phyte · X

@AQICQC @AurelienBrnrd @newsweedFR Malheureusement l'effet d'entourage n'existe visiblement pas, c'etait une bonne hypothèse de Mechoulam au début des années 2000, mais depuis la science a évoluée, et a largement démontré que ce n'était pas probant. https://t.co/Ad9NjSlPYc

Aug 19, 2023 · 995 followers View post →
rkztkt
@rkztktremi · X

@420revolt @Dokyuso2012Tdn @rengoku56771 アントラージュ効果には科学的根拠がない。マーケティングのスローガンなのです。ひょっとして、あなたはベンダーですか？ https://t.co/HYM5kxVm5I こんにゃくゼリーやお餅は、メディア全体が「悪影響はゼロだ」と消費を推奨しているわけではありません。

Apr 20, 2023 · 164 followers View post →
Association of Cannabinoid Specialists
@cannaspecialist · X

RT @cannaspecialist: Evidence for the widely touted Entourage is thin The ‘entourage effect’ or ‘hodge-podge hashish’: the questionable re…

Apr 19, 2023 · 3 shares · 673 followers View post →
Balázs Szigeti
@psybalazs · X

@ClawHelton @GCampbellPsych Is there any hard evidence for the differential effects of #CBD isolate vs full spectrum (without D9THC) CBD products? I am somewhat suspicious of the 'entourage effect' after reading this https://t.co/FDU74liPeG, but admittedly I am not following the literature.

Dec 21, 2022 · 3,272 followers View post →
Association of Cannabinoid Specialists
@cannaspecialist · X

RT @cannaspecialist: Evidence for the widely touted Entourage is thin The ‘entourage effect’ or ‘hodge-podge hashish’: the questionable re…

Mar 21, 2022 · 1 share · 673 followers View post →
Saturn Fan
@JimtheBruce1 · X

@pukeuprainbows @politico University School of Pharmacy, Denver, CO Claims of a cannabis entourage effect invoke ill-defined and unsubstantiated pharmacological activities which are commonly leveraged toward the popularization and sale of ostensible therapeutic products. https://t.co/eUnnAFrKvf

Nov 8, 2021 · 122 followers View post →
Intl. Academy on the Science & Impact of Cannabis
@IASIC3 · X

From a 2020 article in Expert Review of Clinical Pharmacology author Peter Cogan penned an opinion piece and literature review of the broad definition of the entourage effect. #MedicalEffects #PublicHealth #EntourageEffect https://t.co/1WFf0xIrVu

Nov 4, 2021 · 504 followers View post →
CosmHeimdall ⚛
@CosmHeimdall · X

RT @cannaspecialist: Evidence for the widely touted Entourage is thin The ‘entourage effect’ or ‘hodge-podge hashish’: the questionable re…

Jun 30, 2021 · 3 shares · 1,272 followers View post →
Greenthumb_one
@Greenthumb_one · X

The ‘entourage effect’ or ‘hodge-podge hashish’: the questionable rebranding, marketing, and expectations of cannabis polypharmacy [full-text pdf] https://t.co/lOKS8DOUsx #publichealthfirst https://t.co/zI81W5AI74 https://t.co/TralXpFlhr

Jun 30, 2021 · 1 like · 4,510 followers View post →
Association of Cannabinoid Specialists
@cannaspecialist · X

Evidence for the widely touted Entourage is thin The ‘entourage effect’ or ‘hodge-podge hashish’: the questionable rebranding, marketing, and expectations of cannabis polypharmacy https://t.co/hvCkWTBPV4 #cannabis #medicine #patients #doctors @nejm @JAMA_current @CannabisJrnl https://t.co/4ZIA2RuHet

Jun 30, 2021 · 3 likes · 3 shares · 673 followers View post →
Association of Cannabinoid Specialists
@cannaspecialist · X

Evidence for the widely touted Entourage is thin The ‘entourage effect’ or ‘hodge-podge hashish’: the questionable rebranding, marketing, and expectations of cannabis polypharmacy https://t.co/fte5bnqhff #cannabis #medicine #patients #doctors @nejm @JAMA_current @CannabisJrnl https://t.co/m9k1tVOwyf

Feb 3, 2021 · 1 like · 1 share · 673 followers View post →
Jordan Tishler MD
@JordanTishlerMD · X

Evidence for the widely touted Entourage is thin The ‘entourage effect’ or ‘hodge-podge hashish’: questionable rebranding, marketing, & expectations of cannabis polypharmacy https://t.co/zr9WPpVMhb #mmj #health #wellness #sexuality @bostonglobe @bostonherald @latimes @nytimes https://t.co/uBStAKGrZE

Feb 3, 2021 · 1 share · 4,265 followers View post →
Graham Pechenik
@graham_pechenik · X

@MichaelHaichin @ManojDoss @sage_izzy And the entourage effect is certainly not without criticism: https://t.co/lw8OcWHO61 https://t.co/RM8s5CCpJ3

Jan 8, 2021 · 2 likes · 5,665 followers View post →
しろくま
@bluemoon_bear · X

RT @naoskihund: アントラージュ効果、臨床では十分な根拠が無いかそもそも効果がないと見込まれるってさ。 https://t.co/gh4thhWyUz https://t.co/QBXLV6y8U2 https://t.co/Og2X955bz2

Jan 8, 2021 · 1 share · 96 followers View post →
佐々伸也
@naoskihund · X

アントラージュ効果、臨床では十分な根拠が無いかそもそも効果がないと見込まれるってさ。 https://t.co/gh4thhWyUz https://t.co/QBXLV6y8U2 https://t.co/Og2X955bz2

Jan 8, 2021 · 1 like · 1 share · 4,118 followers View post →
Jim Long
@WIDUWall_I · X

@macbarry5 @RadicalRuss @InAweofArt Not just "one": The 'entourage effect' or 'hodge-podge hashish': the questionable rebranding, marketing, and expectations of cannabis polypharmacy. https://t.co/z6EnIGyoKk https://t.co/aaq2FumfCl

Jul 15, 2020 · 141 followers View post →
Jim Long
@WIDUWall_I · X

@ALGOP The 'entourage effect' or 'hodge-podge hashish': the questionable rebranding, marketing, and expectations of cannabis polypharmacy. From Denver Co. unproven medical benefits of cannabis as medicine. https://t.co/z6EnIGyoKk https://t.co/vi4QfDvbau

Mar 14, 2020 · 141 followers View post →
eksogen
@eksogenisk · X

RT @AmirEnglund: https://t.co/tVVCaCVfsv

Mar 14, 2020 · 4 shares · 1,937 followers View post →
Will Lawn
@Will_Lawn · X

RT @AmirEnglund: https://t.co/tVVCaCVfsv

Mar 13, 2020 · 4 shares · 1,179 followers View post →
Bertoglio lab (FMC/UFSC)
@bertogliolab · X

The ‘entourage effect’ or ‘hodge-podge hashish’: the questionable rebranding, marketing, and expectations of cannabis polypharmacy https://t.co/T3tpbiK1hZ

Mar 12, 2020 · 1,745 followers View post →
Jim Long
@WIDUWall_I · X

@CSTribune Denver CO Pharmacy School on unproven pot medical claims: "The 'entourage effect' or 'hodge-podge hashish': the questionable rebranding, marketing, and expectations of cannabis polypharmacy." https://t.co/z6EnIGyoKk https://t.co/V4UXrBwdo5

Mar 10, 2020 · 141 followers View post →
Jim Long
@WIDUWall_I · X

@Nemopunk15 @Find_Your_CALM From the epicenter of USA pot, Denver, CO. Marketing marijuana not medical medical marijuana. "The 'entourage effect' or 'hodge-podge hashish': the questionable rebranding, marketing, and expectations of cannabis polypharmacy". https://t.co/z6EnIGyoKk https://t.co/T4szOpQDQA

Mar 9, 2020 · 1 like · 141 followers View post →
Jim Long
@WIDUWall_I · X

@MarkBellingShow More evidence of the deceptive practices of the cannabis industry. "The 'entourage effect' or 'hodge-podge hashish': the questionable rebranding, marketing, and expectations of cannabis polypharmacy". https://t.co/z6EnIGyoKk https://t.co/cI9HlvwXRW

Mar 5, 2020 · 141 followers View post →
Jim Long
@WIDUWall_I · X

@SpeakerVos @SenFitzgerald More evidence of the folly of medical pot. "The 'entourage effect' or 'hodge-podge hashish': the questionable rebranding, marketing, and expectations of cannabis polypharmacy". https://t.co/z6EnIGyoKk https://t.co/lJjGgbehcz

Mar 5, 2020 · 141 followers View post →
Jim Long
@WIDUWall_I · X

@wisgop Another study questioning "medical" marijuana. "The 'entourage effect' or 'hodge-podge hashish': the questionable rebranding, marketing, and expectations of cannabis polypharmacy". https://t.co/z6EnIGyoKk https://t.co/t40RvyTjgz

Mar 5, 2020 · 141 followers View post →
Jim Long
@WIDUWall_I · X

@FoxBusiness Why cannabis stocks are a risky investment.The 'entourage effect' or 'hodge-podge hashish': the questionable rebranding, marketing, and expectations of cannabis polypharmacy. https://t.co/z6EnIGyoKk https://t.co/dxpFTFGwnX

Mar 5, 2020 · 141 followers View post →
the paper link
@the_paper_link · X

Trend new: *Cogan PS* (Expert Rev Clin Pharmacol) __The 'entourage effect' or 'hodge-podge hashish': the questionable rebranding, marketing, and expectations of cannabis polypharmacy__ https://t.co/L3l5bzV8bb

Mar 4, 2020 · 137 followers View post →
Manoj Doss not exist
@ManojDoss · X

RT @AmirEnglund: https://t.co/tVVCaCVfsv

Mar 4, 2020 · 4 shares · 6,084 followers View post →
Spellyr
@Sp3llyr · X

RT @AmirEnglund: https://t.co/tVVCaCVfsv

Mar 4, 2020 · 4 shares · 707 followers View post →
Amir Englund
@AmirEnglund · X

https://t.co/tVVCaCVfsv

Mar 4, 2020 · 4 likes · 4 shares · 2,586 followers View post →
cbdmedbot
@cbdmedbot · X

The 'entourage effect' or 'hodge-podge hashish': the questionable rebranding, marketing, and expectations of cannabis polypharmacy. https://t.co/Jz4Is6h1qR

Mar 3, 2020 · 157 followers View post →
The Richard Rose Report
@TheRRreport · X

The 'entourage effect' or 'hodge-podge hashish': the questionable rebranding, marketing, and expectations of cannabis polypharmacy. Expert Rev Clin Pharmacol. 2020 Mar 02;:1-11 Authors: Cogan PS Abstract Introduction: The concept of a cannabis 'entour… https://t.co/u1fFbUVJhl

Mar 3, 2020 · 149 followers View post →
Cannabis Belgique
@CannabisBelge · X

The ‘entourage effect’ or ‘hodge-podge hashish’: the questionable rebranding, marketing, and expectations of cannabis polypharmacy. https://t.co/UNiUmkF3fQ

Mar 3, 2020 · 652 followers View post →
Taverne de Schaka
@TavernedeSchaka · X

The ‘entourage effect’ or ‘hodge-podge hashish’: the questionable rebranding, marketing, and expectations of cannabis polypharmacy. https://t.co/TNDtsLVG7x

Mar 3, 2020 · 291 followers View post →