Dig Dis Sci September 2020 PMID 32140945

Mapping the Segmental Microbiomes in the Human Small Bowel in Comparison with Stool: A REIMAGINE Study.

Gabriela G S Leite, Stacy Weitsman, Gonzalo Parodi, Shreya Celly, Rashin Sedighi, Maritza Sanchez, Walter Morales, Maria Jesus Villanueva-Millan, Gillian M Barlow, Ruchi Mathur, Simon K Lo, Laith H Jamil, Shirley Paski, Ali Rezaie, Mark Pimentel

Mentions

41
Peak: 13 in Nov 2020
across 4 sources since Mar 2020

Extended reach

209,331
potential audience

Total likes

174

Video views

656

Mentions per month

Mar 2020 – Nov 2025

Where it's discussed

  • X / Twitter36 posts
  • YouTube2 videos
  • News2 articles
  • Reddit1 posts

AI synopsis

What people are saying

The social discussions exhibit strong support and interest in the study, with many examples emphasizing the differences in the small intestine microbiome from stool samples, such as mentions of the study's findings on segmental variability and their relevance to disease. The tone and choice of words like 'striking differences' and 'important' underline the perceived significance and potential impact of this research on understanding human health.

AgreementModerate agreement

Most discussions support the significance of the findings, emphasizing the differences in the small bowel microbiome compared to stool and highlighting the study's contributions.

InterestHigh interest

The posts demonstrate high interest through references to specific details, such as the variations between intestinal segments and implications for health, showing curiosity and engagement with the topic.

EngagementModerate engagement

Several comments reference complex concepts like microbial populations, operational taxonomic units, and the need for targeted small bowel analysis, indicating thoughtful engagement beyond surface-level discussion.

ImpactHigh impact

The discussions suggest that this research could substantially influence future clinical practices and microbiome research, as emphasized by comments on how stool tests might be insufficient or the importance of segment-specific microbiome data.

Abstract in brief

  • The study highlights that the microbial communities in the human small intestine are significantly different from those found in stool, with specific bacterial groups like Firmicutes and Proteobacteria being predominant in the small intestine.
  • Different segments of the small bowel (duodenum, jejunum, and further down) have distinct microbial signatures, although some overlap exists between segments.
  • These findings suggest that analyzing small intestine microbes separately from stool is important, as changes in their composition may play a role in human health and disease.

Top posts

Most liked on X and Bluesky
GutMicrobiota Health
@GMFHx · X

The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duodenal and stool microbiomes in the same subjects (stool samples don't allow us to get the whole picture!) https://t.co/vUzwjVzqa4

Nov 5, 2020 · 61 likes · 19 shares · 35,587 followers View post →
Gabor Erdosi
@gerdosi · X

“The small bowel microbiome is markedly different from that in stool and also varies between segments. These findings may be important in determining how compositional changes in small intestinal microbiota contribute to human disease states.” https://t.co/Dcld87Zh6g

Mar 16, 2020 · 29 likes · 1 share · 25,851 followers View post →
GutMicrobiota Health
@GMFHx · X

The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duodenal and stool microbiomes in the same subjects https://t.co/pQlHjzSCnx

Dec 7, 2020 · 20 likes · 5 shares · 35,587 followers View post →
GutMicrobiota Health
@GMFHx · X

The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duodenal and stool microbiomes in the same subjects https://t.co/AI1GX54YaP

Nov 16, 2020 · 17 likes · 4 shares · 35,587 followers View post →
MAST Research Program
@MASTprogram · X

Let's “set sail” on the #REIMAGINE1000 campaign! Our nautical journey begins with a @DDS_Journal paper that identified microbial populations of different duodenal segments & compared these to stool #microbiome https://t.co/WnFOfqVO8Y The study couldn’t have been possible w/o the https://t.co/WHvHph6KDb

Sep 17, 2024 · 8 likes · 2 shares · 3,139 followers View post →
Sean Spencer, MD, PhD
@SeanPaulSpencer · X

Foundational work by @MarkPimentelMD, @MASTprogram, @GabrielaGSLeite, @AliRezaieMD PMID: 32140945- https://t.co/oW4rear8Hm PMID: 37315761- https://t.co/BuHG9sE0hR 13/n

Apr 26, 2024 · 7 likes · 1 share · 1,233 followers View post →

All mentions

Ruchi Mathur MD
@RuchiMathurMD · X

RT @MASTprogram: Let's “set sail” on the #REIMAGINE1000 campaign! Our nautical journey begins with a @DDS_Journal paper that identified mic…

Sep 18, 2024 · 2 shares · 1,697 followers View post →
viscerainstytut
@viscerainstytut · X

RT @MASTprogram: Let's “set sail” on the #REIMAGINE1000 campaign! Our nautical journey begins with a @DDS_Journal paper that identified mic…

Sep 18, 2024 · 2 shares · 22 followers View post →
MAST Research Program
@MASTprogram · X

Let's “set sail” on the #REIMAGINE1000 campaign! Our nautical journey begins with a @DDS_Journal paper that identified microbial populations of different duodenal segments & compared these to stool #microbiome https://t.co/WnFOfqVO8Y The study couldn’t have been possible w/o the https://t.co/WHvHph6KDb

Sep 17, 2024 · 8 likes · 2 shares · 3,139 followers View post →
Ali Rezaie MD MSc
@AliRezaieMD · X

RT @SeanPaulSpencer: Foundational work by @MarkPimentelMD, @MASTprogram, @GabrielaGSLeite, @AliRezaieMD PMID: 32140945- https://t.co/oW4rea…

Apr 26, 2024 · 1 share · 5,137 followers View post →
Sean Spencer, MD, PhD
@SeanPaulSpencer · X

Foundational work by @MarkPimentelMD, @MASTprogram, @GabrielaGSLeite, @AliRezaieMD PMID: 32140945- https://t.co/oW4rear8Hm PMID: 37315761- https://t.co/BuHG9sE0hR 13/n

Apr 26, 2024 · 7 likes · 1 share · 1,233 followers View post →
Peter Voshol
@Peter_Voshol · X

RT @gerdosi: “The small bowel microbiome is markedly different from that in stool and also varies between segments. These findings may be i…

Sep 10, 2021 · 1 share · 1,895 followers View post →
Pam Emmer
@lifeaftersibo · X

RT @john_damianosMD: @mcarlin33 @ProbioticDr @NardineN3 @ISAPPscience @armstro265 @reid_probiotics More recently from @MarkPimentelMD and t…

Jul 10, 2021 · 1 share · 831 followers View post →
John Damianos, M.D.
@john_damianosMD · X

@mcarlin33 @ProbioticDr @NardineN3 @ISAPPscience @armstro265 @reid_probiotics More recently from @MarkPimentelMD and the REIMAGINE study https://t.co/M7vjskskgR https://t.co/JHLzHZMjPr

Jul 5, 2021 · 5 likes · 1 share · 24,130 followers View post →
Ali Arj
@AliArjomand · X

The small intestinal #microbiome is markedly different from that in #stool. Direct-to-consumer stool tests don't capture changes in the small intestinal microbiota. Don't #wasteyourmoney with stool tests if evaluating small intestinal #microbiome! https://t.co/aIl9Ttcz7L https://t.co/eI69qMh5lN

Feb 23, 2021 · 1 like · 784 followers View post →
Jordan Russell, Ph.D
@russelltyjor · X

RT @metagenomic_lit: Mapping the Segmental Microbiomes in the Human Small Bowel in Comparison with Stool: A REIMAGINE Study. https://t.co/n…

Dec 30, 2020 · 1 share · 122 followers View post →
Metagenomics Papers
@metagenomic_lit · X

Mapping the Segmental Microbiomes in the Human Small Bowel in Comparison with Stool: A REIMAGINE Study. https://t.co/npU7FhsdUA

Dec 30, 2020 · 1 like · 1 share · 3,687 followers View post →
Aline
@Aline42206985 · X

RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…

Dec 7, 2020 · 5 shares · 11 followers View post →
4QuorumSensing
@4QuorumSensing · X

RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…

Dec 7, 2020 · 5 shares · 6,326 followers View post →
GutMicrobiota Health
@GMFHx · X

The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duodenal and stool microbiomes in the same subjects https://t.co/pQlHjzSCnx

Dec 7, 2020 · 20 likes · 5 shares · 35,587 followers View post →
GutMicrobiota Health
@GMFHx · X

The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duodenal and stool microbiomes in the same subjects https://t.co/AI1GX54YaP

Nov 16, 2020 · 17 likes · 4 shares · 35,587 followers View post →
CholoQ
@chol_gyu · X

RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…

Nov 5, 2020 · 19 shares · 1,372 followers View post →
Sneha Surya Narayana Murthy
@MurthySneha · X

RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…

Nov 5, 2020 · 19 shares · 425 followers View post →
ImmunoLatinXs "Científicos Comunicando Ciencia"
@ImmunoLatinXs · X

RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…

Nov 5, 2020 · 19 shares · 1,564 followers View post →
Yolanda Sanz
@YolandaSanz_Lab · X

RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…

Nov 5, 2020 · 19 shares · 459 followers View post →
Mark A Carlson
@macsun · X

RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…

Nov 5, 2020 · 19 shares · 740 followers View post →
Ildiko ☕️
@IldikoMe · X

RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…

Nov 5, 2020 · 19 shares · 1,773 followers View post →
UCCpsychiatry
@UCCpsychiatry · X

RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…

Nov 5, 2020 · 19 shares · 3,526 followers View post →
Viviana
@VivianAya93 · X

RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…

Nov 5, 2020 · 19 shares · 133 followers View post →
Shared Nutrition ❣️
@sharednutrition · X

RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…

Nov 5, 2020 · 19 shares · 98 followers View post →
Benjamin Gold
@BenjamminGold · X

RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…

Nov 5, 2020 · 19 shares · 2,064 followers View post →
GutMicrobiota Health
@GMFHx · X

The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duodenal and stool microbiomes in the same subjects (stool samples don't allow us to get the whole picture!) https://t.co/vUzwjVzqa4

Nov 5, 2020 · 61 likes · 19 shares · 35,587 followers View post →
MAST Research Program
@MASTprogram · X

Cover of .@DDS_Journal September 2020 ~ We show the small bowel #microbiome is different from that in stool and varies between segments. This may be important in determining how compositional changes in small intestinal microbiota contribute to disease. https://t.co/IQPaZ2mNml https://t.co/YgHO04pZ5Q

Nov 3, 2020 · 6 likes · 3,139 followers View post →
Digestive Diseases and Sciences
@DDS_Journal · X

September Issue! https://t.co/WbLfd3Klot COVID-2019.2 Reboot: Returning a GI Fellowship to Pre-pandemic Practices How Can FLIP Enhance Your Clinical Practice? Mapping the Segmental #Microbiomes in the Human Small Bowel in Comparison with Stool: A REIMAGINE Study https://t.co/hPy7RBG1I8

Aug 11, 2020 · 867 followers View post →
Marit Kolby
@MaritKolby · X

@ggkuhnle @BenoitChassaing And - forget the fecal microbiota. We need to worry about what's going on in the small bowel. That's where inflammation is induced. Look up @gerdosi and read the papers in his pinned tweet, lot's of useful info. Let me know if you want more :-) https://t.co/KnMs1uP1CW

Jul 1, 2020 · 1 like · 4,899 followers View post →
Gabor Erdosi
@gerdosi · X

“The small bowel microbiome is markedly different from that in stool and also varies between segments. These findings may be important in determining how compositional changes in small intestinal microbiota contribute to human disease states.” https://t.co/Dcld87Zh6g

Mar 16, 2020 · 29 likes · 1 share · 25,851 followers View post →
ibs-smart
@ibssmart · X

RT @MASTprogram: Results from the #REIMAGINEStudy: 16S rRNA sequencing identified differences in over 2000 operational taxonomic units betw…

Mar 13, 2020 · 3 shares · 525 followers View post →
Gemelli Biotech
@GemelliBiotech · X

RT @MASTprogram: Results from the #REIMAGINEStudy: 16S rRNA sequencing identified differences in over 2000 operational taxonomic units betw…

Mar 13, 2020 · 3 shares · 418 followers View post →
Dimiter Dimitrov MD PhD
@SystemsMedicine · X

REIMAGINE Study (Small Intestine #Microbiome): https://t.co/DUVuctFeKM https://t.co/H8337DJuv3

Mar 11, 2020 · 253 followers View post →
Craig Cheyne
@craigcheyne1 · X

RT @MASTprogram: Results from the #REIMAGINEStudy: 16S rRNA sequencing identified differences in over 2000 operational taxonomic units betw…

Mar 10, 2020 · 3 shares · 14 followers View post →
MAST Research Program
@MASTprogram · X

Results from the #REIMAGINEStudy: 16S rRNA sequencing identified differences in over 2000 operational taxonomic units between the small intestinal and stool #microbiomes. https://t.co/dzITah9W6z https://t.co/56bnM8DJHk

Mar 10, 2020 · 6 likes · 3 shares · 3,139 followers View post →
Symbiosis papers
@Symbiosispapers · X

Mapping the Segmental Microbiomes in the Human Small Bowel in Comparison with Stool: A REIMAGINE Study. https://t.co/DYoItMf7Vd

Mar 7, 2020 · 1,104 followers View post →
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