The social discussions exhibit strong support and interest in the study, with many examples emphasizing the differences in the small intestine microbiome from stool samples, such as mentions of the study's findings on segmental variability and their relevance to disease. The tone and choice of words like 'striking differences' and 'important' underline the perceived significance and potential impact of this research on understanding human health.
AgreementModerate agreement
Most discussions support the significance of the findings, emphasizing the differences in the small bowel microbiome compared to stool and highlighting the study's contributions.
InterestHigh interest
The posts demonstrate high interest through references to specific details, such as the variations between intestinal segments and implications for health, showing curiosity and engagement with the topic.
EngagementModerate engagement
Several comments reference complex concepts like microbial populations, operational taxonomic units, and the need for targeted small bowel analysis, indicating thoughtful engagement beyond surface-level discussion.
ImpactHigh impact
The discussions suggest that this research could substantially influence future clinical practices and microbiome research, as emphasized by comments on how stool tests might be insufficient or the importance of segment-specific microbiome data.
Abstract in brief
The study highlights that the microbial communities in the human small intestine are significantly different from those found in stool, with specific bacterial groups like Firmicutes and Proteobacteria being predominant in the small intestine.
Different segments of the small bowel (duodenum, jejunum, and further down) have distinct microbial signatures, although some overlap exists between segments.
These findings suggest that analyzing small intestine microbes separately from stool is important, as changes in their composition may play a role in human health and disease.
The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duodenal and stool microbiomes in the same subjects (stool samples don't allow us to get the whole picture!) https://t.co/vUzwjVzqa4
Nov 5, 2020 · 61 likes · 19 shares · 35,587 followersView post →
GE
Gabor Erdosi
@gerdosi · X
“The small bowel microbiome is markedly different from that in stool and also varies between segments. These findings may be important in determining how compositional changes in small intestinal microbiota contribute to human disease states.”
https://t.co/Dcld87Zh6g
Mar 16, 2020 · 29 likes · 1 share · 25,851 followersView post →
GH
GutMicrobiota Health
@GMFHx · X
The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duodenal and stool microbiomes in the same subjects https://t.co/pQlHjzSCnx
Dec 7, 2020 · 20 likes · 5 shares · 35,587 followersView post →
GH
GutMicrobiota Health
@GMFHx · X
The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duodenal and stool microbiomes in the same subjects https://t.co/AI1GX54YaP
Nov 16, 2020 · 17 likes · 4 shares · 35,587 followersView post →
MP
MAST Research Program
@MASTprogram · X
Let's “set sail” on the #REIMAGINE1000 campaign! Our nautical journey begins with a @DDS_Journal paper that identified microbial populations of different duodenal segments & compared these to stool #microbiome https://t.co/WnFOfqVO8Y
The study couldn’t have been possible w/o the https://t.co/WHvHph6KDb
Why is SIBO small intestinal bowel overgrowth challenging to treat? This video discusses the importance of exploring root causes beyond immediate symptom management, considering the distinct microbiomes in different…
Let's “set sail” on the #REIMAGINE1000 campaign! Our nautical journey begins with a @DDS_Journal paper that identified microbial populations of different duodenal segments & compared these to stool #microbiome https://t.co/WnFOfqVO8Y
The study couldn’t have been possible w/o the https://t.co/WHvHph6KDb
@mcarlin33 @ProbioticDr @NardineN3 @ISAPPscience @armstro265 @reid_probiotics More recently from @MarkPimentelMD and the REIMAGINE study
https://t.co/M7vjskskgR https://t.co/JHLzHZMjPr
The small intestinal #microbiome is markedly different from that in #stool. Direct-to-consumer stool tests don't capture changes in the small intestinal microbiota. Don't #wasteyourmoney with stool tests if evaluating small intestinal #microbiome!
https://t.co/aIl9Ttcz7L https://t.co/eI69qMh5lN
RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…
Dec 7, 2020 · 5 shares · 6,326 followersView post →
GH
GutMicrobiota Health
@GMFHx · X
The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duodenal and stool microbiomes in the same subjects https://t.co/pQlHjzSCnx
Dec 7, 2020 · 20 likes · 5 shares · 35,587 followersView post →
GH
GutMicrobiota Health
@GMFHx · X
The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duodenal and stool microbiomes in the same subjects https://t.co/AI1GX54YaP
Nov 16, 2020 · 17 likes · 4 shares · 35,587 followersView post →
C
CholoQ
@chol_gyu · X
RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…
Nov 5, 2020 · 19 shares · 1,372 followersView post →
SM
Sneha Surya Narayana Murthy
@MurthySneha · X
RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…
Nov 5, 2020 · 19 shares · 425 followersView post →
IC
ImmunoLatinXs "Científicos Comunicando Ciencia"
@ImmunoLatinXs · X
RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…
Nov 5, 2020 · 19 shares · 1,564 followersView post →
YS
Yolanda Sanz
@YolandaSanz_Lab · X
RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…
Nov 5, 2020 · 19 shares · 459 followersView post →
MC
Mark A Carlson
@macsun · X
RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…
Nov 5, 2020 · 19 shares · 740 followersView post →
I
Ildiko ☕️
@IldikoMe · X
RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…
Nov 5, 2020 · 19 shares · 1,773 followersView post →
U
UCCpsychiatry
@UCCpsychiatry · X
RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…
Nov 5, 2020 · 19 shares · 3,526 followersView post →
V
Viviana
@VivianAya93 · X
RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…
Nov 5, 2020 · 19 shares · 133 followersView post →
SN
Shared Nutrition ❣️
@sharednutrition · X
RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…
RT @GMFHx: The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duoden…
Nov 5, 2020 · 19 shares · 2,064 followersView post →
GH
GutMicrobiota Health
@GMFHx · X
The small intestine remains largely overlooked in microbiome science. New research finds striking differences between the duodenal and stool microbiomes in the same subjects (stool samples don't allow us to get the whole picture!) https://t.co/vUzwjVzqa4
Nov 5, 2020 · 61 likes · 19 shares · 35,587 followersView post →
MP
MAST Research Program
@MASTprogram · X
Cover of .@DDS_Journal September 2020 ~ We show
the small bowel #microbiome is different from that in stool and varies between segments. This may be important in determining how compositional changes in small intestinal microbiota contribute to disease. https://t.co/IQPaZ2mNml https://t.co/YgHO04pZ5Q
Nov 3, 2020 · 6 likes · 3,139 followersView post →
DS
Digestive Diseases and Sciences
@DDS_Journal · X
September Issue! https://t.co/WbLfd3Klot
COVID-2019.2 Reboot: Returning a GI Fellowship to Pre-pandemic Practices
How Can FLIP Enhance Your Clinical Practice?
Mapping the Segmental #Microbiomes in the Human Small Bowel in Comparison with Stool: A REIMAGINE Study https://t.co/hPy7RBG1I8
@ggkuhnle @BenoitChassaing And - forget the fecal microbiota. We need to worry about what's going on in the small bowel. That's where inflammation is induced. Look up @gerdosi and read the papers in his pinned tweet, lot's of useful info. Let me know if you want more :-) https://t.co/KnMs1uP1CW
“The small bowel microbiome is markedly different from that in stool and also varies between segments. These findings may be important in determining how compositional changes in small intestinal microbiota contribute to human disease states.”
https://t.co/Dcld87Zh6g
Mar 16, 2020 · 29 likes · 1 share · 25,851 followersView post →
IS
ibs-smart
@ibssmart · X
RT @MASTprogram: Results from the #REIMAGINEStudy:
16S rRNA sequencing identified differences in over 2000 operational taxonomic units betw…
Mar 13, 2020 · 3 shares · 525 followersView post →
GB
Gemelli Biotech
@GemelliBiotech · X
RT @MASTprogram: Results from the #REIMAGINEStudy:
16S rRNA sequencing identified differences in over 2000 operational taxonomic units betw…
Mar 13, 2020 · 3 shares · 418 followersView post →
DP
Dimiter Dimitrov MD PhD
@SystemsMedicine · X
REIMAGINE Study (Small Intestine #Microbiome): https://t.co/DUVuctFeKM https://t.co/H8337DJuv3
Results from the #REIMAGINEStudy:
16S rRNA sequencing identified differences in over 2000 operational taxonomic units between the small intestinal and stool #microbiomes.
https://t.co/dzITah9W6z https://t.co/56bnM8DJHk
Mar 10, 2020 · 6 likes · 3 shares · 3,139 followersView post →
SP
Symbiosis papers
@Symbiosispapers · X
Mapping the Segmental Microbiomes in the Human Small Bowel in Comparison with Stool: A REIMAGINE Study. https://t.co/DYoItMf7Vd
Resolving The Paradox of Colon Cancer | PDF | Gastrointestinal ...
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doi: 10.1007/s10620-020-06173-x colonic mucosa by using 16S rDNA sequence analysis. J Appl Microbiol 124. Wang M, Ahrné S, Jeppsson B, Molin G. Comparison ...