Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/YEy0HP5p8v Plus: @HoLabHIV 's commentary: SARS-CoV-2: a storm is raging https://t.co/yRf8VqFZ7U https://t.co/m2hHfp3dK4
Clinical and immunological features of severe and moderate coronavirus disease 2019.
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Mar 2020 – Mar 2025Where it's discussed
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AI synopsis
What people are saying
In the discussions, several users pointed out key findings from the article, such as the relationship between T cell levels and the severity of COVID-19, with one user noting how severe cases show significantly depleted CD4 and CD8 T cells. Others mentioned how particular biomarkers, like LDH levels, correlate with COVID severity, using terms like 'critical' and 'urgent' to underline the study's relevance, thus contributing to a tone of seriousness and urgency in addressing the pandemic.
Many discussions reflect a consensus on the importance of the findings presented in the publication.
Users express a high level of curiosity regarding the clinical and immunological aspects of COVID-19 severity.
Posts often reference specific findings and implications, indicating thoughtful consideration of the paper's content.
Participants perceive the research as crucial for understanding COVID-19, believing it could influence treatments and clinical practices.
Abstract in brief
- The study analyzes the clinical and immunological differences between severe and moderate cases of COVID-19 in 21 patients, revealing that severe cases show more respiratory distress and significant immune system impacts.
- Severe cases had higher levels of inflammation markers and lower counts of T lymphocytes, especially CD4 and CD8 cells, suggesting a compromised immune response.
- These findings highlight potential immunological indicators that could correlate with the severity of COVID-19, emphasizing the importance of monitoring T cell levels in affected patients.
Top posts
Most liked on X and BlueskyOtros estudios han relacionado los niveles bajos de albúmina con resultados deficientes en COVID-19. https://t.co/akrjIOBUMV https://t.co/DsU8Vuii4t https://t.co/cearul3j6i
Understanding immune activation #inflammation and severity of SARS-CoV-2 @jclinicalinvest Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/sJnuvoNtZJ
@gfj1979 @zinocker Check recent clinical reports on COVID-19. More severe cases [E.g. in Table 2. of reference below] typically show high(ish) neutrophils, but definitely a high neutrophil-to-lymphocyte ratio (NLR). There are even studies reporting on the NLR in COVID. https://t.co/PJpYZpFVP6
(5) Patients with moderate vs. severe COVID-19 have an altered distribution of Treg subsets (e.g., severe cases w/ lower proportion of nTregs and higher proportion of mTregs), suggesting that therapies that re-establish Treg homeostasis may be beneficial. https://t.co/RGLGhoGDwd
RT @jclinicalinvest: Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/CEpIDFuiMA Plus: @HoLabHIV 's commentary: SARS-CoV-2: a storm is raging https://t.co/JS0gfLTsbV https://t.co/19w9l4BGrR
All mentions
Understanding COVID-19: Transmission and Complications
Neste vídeo, iremos falar sobre COVID-19, suas origens e modos de transmissão. Estudaremos ainda as complicações de coagulação, onde altos índices de trombose e sangramento foram observados. Aprofunde-se nos tratamentos…
Understanding COVID-19 Tests and Symptoms
This video explains COVID-19 transmission, symptoms, and how testing works, based on research from the University of Brasilia. It aims to provide a clear understanding of how COVID-19 is detected and its health impacts.
Mar 27, 2020 the retrospective study based on the data released by the National Health Commission of China shows "the median age of severe and moderate cases was 61.0 and 52.0 years, respectively”, the observation confirmed later. https://t.co/9XqFLlFZFi https://t.co/z0tFA50zxw
@kerstinmitk @RealGayArbys https://t.co/O7CexgEhG3
#Sars https://t.co/lu4NdWbzF8
@IsabellWelpe @WinfriedFelser @MarcBrup @fitterhappierAJ Effekte auf das Inflammasom und myeloide Zellen: https://t.co/lJzRFQG3S5 Effekte auf T Zellen: https://t.co/oM8ilLrcgM SARS2➡️Diabetes: https://t.co/vC8tInOfut Außerdem viele paper zu Thrombosen. Warum früh Paxlovid? Begrenzt ggf Infektion auf obere Atemwege➡️wenig Schäden
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/lwAUr2r0LN
JCI - Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/6LFYVJU3nj
https://t.co/4Tr48KsSlG
RT @Tony_Calles:
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
@The_Oysterlady @drdpogson @DECENTRADICAL @MichaelYeadon3 All pts on ICU with COVID-19 will have been seen by many specialists, many times, had many tests, & the diagnosis will have been confirmed with CT scans... ...it's a well defined new clinical syndrome, not dependant solely on PCR testing. [ref: https://t.co/vtuai3kwE8] https://t.co/Np9JkWoh1M
RT @IlindelatorreMD: Otros estudios han relacionado los niveles bajos de albúmina con resultados deficientes en COVID-19. https://t.co/ak…
RT @IlindelatorreMD: Otros estudios han relacionado los niveles bajos de albúmina con resultados deficientes en COVID-19. https://t.co/ak…
RT @IlindelatorreMD: Otros estudios han relacionado los niveles bajos de albúmina con resultados deficientes en COVID-19. https://t.co/ak…
Otros estudios han relacionado los niveles bajos de albúmina con resultados deficientes en COVID-19. https://t.co/akrjIOBUMV https://t.co/DsU8Vuii4t https://t.co/cearul3j6i
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @jclinicalinvest: Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/YEy0HP5p8v Plus: @H…
RT @jclinicalinvest: Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/YEy0HP5p8v Plus: @H…
RT @jclinicalinvest: Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/YEy0HP5p8v Plus: @H…
@StevePhillipsMD @JamesTodaroMD https://t.co/kdsMf5twSK
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
(5) Patients with moderate vs. severe COVID-19 have an altered distribution of Treg subsets (e.g., severe cases w/ lower proportion of nTregs and higher proportion of mTregs), suggesting that therapies that re-establish Treg homeostasis may be beneficial. https://t.co/RGLGhoGDwd
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
Clinical and immunological features of severe and moderate coronavirus disease 2019: https://t.co/0b4lhy8WmB Related commentary: https://t.co/SyYsR28jc9 https://t.co/oipkhIkvB3
#CoronavirusESP #EsteVirusLoParamosUnidos #QuedateEnCasa Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/9Dj7Ql6eyi https://t.co/CMxG9c20Xu
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @AurelioOrta: Tocilizumab is a monoclonal antibody that binds the IL-6 receptor (CD126). In the past months, higher levels of IL-6 were…
Tocilizumab is a monoclonal antibody that binds the IL-6 receptor (CD126). In the past months, higher levels of IL-6 were documented in patients with severe COVID-19 during a cytokine storm https://t.co/uGOjyPb6zX https://t.co/YflHILkSbU
@fordnation https://t.co/kdsMf5bW1c
“Clinical and immunological features of [21 cases of] severe and moderate coronavirus disease 2019” https://t.co/DjLKFTYMGJ This paper discusses potential immunological markers of #Covid19 disease severity. #immunology #Cytokine https://t.co/yf1w7co6KE
RT @jclinicalinvest: Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/CEpIDFuiMA Plus: @HoLabHIV 's commentary: SARS-CoV-2: a storm is raging https://t.co/JS0gfLTsbV https://t.co/19w9l4BGrR
RT @jclinicalinvest: Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/YEy0HP5p8v Plus: @H…
RT @minesoh: JCI
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RT @jclinicalinvest: Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/YEy0HP5p8v Plus: @H…
RT @jclinicalinvest: JUST PUBLISHED: Clinical and immunologic features in severe and moderate Coronavirus Disease 2019 https://t.co/qBROIs4…
https://t.co/D0IsVWzTJb
@AaronRichterman @EricMeyerowitz Thanks for sharing. I saw this JCI paper that showed by CD4 and CD8 t cells were depleted in more severe cases (11 severe v 10 moderate) https://t.co/4XZ2sxnohU https://t.co/aTU1hwDgkO
RT @jclinicalinvest: Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/YEy0HP5p8v Plus: @H…
RT @jclinicalinvest: Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/YEy0HP5p8v Plus: @H…
RT @jclinicalinvest: Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/YEy0HP5p8v Plus: @H…
RT @jclinicalinvest: Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/YEy0HP5p8v Plus: @H…
JCI - Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/DhywVP0Twr
RT @jclinicalinvest: Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/YEy0HP5p8v Plus: @H…
RT @jclinicalinvest: Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/YEy0HP5p8v Plus: @H…
JCI: Caractéristiques cliniques et immunologiques des coronavirus sévères et modérés 2019 https://t.co/5pamP8354B Plus: @HoLabHIV Commentaire de SARS-CoV-2: une tempête fait rage https://t.co/IURjwabtVH https://t.co/TWtZEGaQX1
RT @jclinicalinvest: Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/YEy0HP5p8v Plus: @H…
RT @jclinicalinvest: Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/YEy0HP5p8v Plus: @H…
RT @jclinicalinvest: Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/YEy0HP5p8v Plus: @H…
RT @jclinicalinvest: Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/YEy0HP5p8v Plus: @H…
RT @jclinicalinvest: Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/YEy0HP5p8v Plus: @H…
Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/YEy0HP5p8v Plus: @HoLabHIV 's commentary: SARS-CoV-2: a storm is raging https://t.co/yRf8VqFZ7U https://t.co/m2hHfp3dK4
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @Tony_Calles:
RT @Tony_Calles:
Understanding immune activation #inflammation and severity of SARS-CoV-2 @jclinicalinvest Clinical and immunological features of severe and moderate coronavirus disease 2019 https://t.co/sJnuvoNtZJ
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @AurelioOrta: @profvrr Indeed is very interesting. Similar findings are described in a paper of a small study of severe cases where they…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @Tony_Calles:
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
RT @VirusesImmunity: Several studies are coming out saying that blood LDH (lactate dehydrogenase) levels early in #COVID19 disease correlat…
Características clínicas e inmunológicas en la enfermedad moderada y grave por #Covid19 La disnea y el fracaso respiratorio al 8vo de la enfermedad esta muy asociada a la #tormentaDeCitoquinas con caida severa de linfocitos T, células T CD4 + T y CD8 https://t.co/2UqYQDKPXg https://t.co/zHgxM7VUQY
@GenoceaBio @jessaflecht @TheChipClark Potential application for ATLAS? FYI: “Clinical and Immunologic Features in Severe and Moderate Coronavirus Disease 2019” https://t.co/YnGvHCW6Ym 1/2 https://t.co/RniBOJqHJb
Clinical and immunologic features in severe and moderate Coronavirus Disease 2019. Chen et al. @SaludISCIII @CNB_CSIC #ProteoRed #Paper #Proteomics #COVID19 https://t.co/b3KOT0UrNP https://t.co/BOgcqWWHaj
@gfj1979 @zinocker Check recent clinical reports on COVID-19. More severe cases [E.g. in Table 2. of reference below] typically show high(ish) neutrophils, but definitely a high neutrophil-to-lymphocyte ratio (NLR). There are even studies reporting on the NLR in COVID. https://t.co/PJpYZpFVP6
SARS-CoV-2: A Storm is Raging J Clin Invest. 2020-03-27. https://t.co/8om2XnU7XN Clinical and immunologic features in severe and moderate Coronavirus Disease 2019 J Clin Invest. 2020-03-27. https://t.co/Nkcv3QiWH0