J Med Virol July 2020 PMID 32221983

Organ-protective effect of angiotensin-converting enzyme 2 and its effect on the prognosis of COVID-19.

Hao Cheng, Yan Wang, Gui-Qiang Wang

Mentions

15
Peak: 7 in Mar 2020
across 3 sources since Mar 2020

Extended reach

7,393
potential audience

Total likes

14

Video views

176

Mentions per month

Mar 2020 – Nov 2021

Where it's discussed

  • X / Twitter11 posts
  • YouTube2 videos
  • News2 articles

AI synopsis

What people are saying

Discussions highlight the potential organ-protective effects of ACE2 in COVID-19, with posts mentioning medications like losartan and ARBs, and emphasizing the biological mechanisms involved. The tone reflects curiosity and recognition of the research's implications for ongoing treatment debates, demonstrating both active interest and moderate engagement.

AgreementModerate agreement

Most discussions support the idea that ACE2 has a protective role in COVID-19, with some mentioning the potential benefits of medications like losartan and ARBs.

InterestHigh interest

The posts show high interest, referencing specific drugs, mechanisms, and implications for treatment, indicating active engagement.

EngagementModerate engagement

Several responses discuss the research details and its relevance to treatment strategies, reflecting a moderate depth of engagement.

ImpactModerate impact

Participants seem to believe that this research could influence clinical approaches, hinting at a notable impact on scientific and medical perspectives.

Abstract in brief

  • The article discusses how ACE2, an important enzyme in the body's renin-angiotensin system, helps protect organs like the heart, lungs, and kidneys from damage and may influence the severity of COVID-19.
  • Both SARS-CoV and the coronavirus SARS-CoV-2 use the ACE2 receptor to infect human cells, which can lead to severe lung issues like acute respiratory distress syndrome (ARDS), often associated with high mortality.
  • Due to ACE2's protective roles, especially against conditions like hypertension and organ damage, developing vaccines and drugs that enhance ACE2 activity could be a promising strategy for treating COVID-19 in the future.]

Top posts

Most liked on X and Bluesky
Mishima Eikan
@eikan_em · X

ACE2発現が高いことがコロナ感染に対していいのか悪いのかはcontroversy. この総説ではACE2善玉説の立場で論述。 加齢で肺ACE2減少、ACEI/ARBによるACE2発現増加はよいことかも、rhACE2投与が治療になるかもと記載。J Med Virol誌 #COVID19 https://t.co/UjAoNob3sn

Mar 30, 2020 · 4 likes · 422 followers View post →
Auge Aabye
@AugeAabye · X

Se sigue evaluando si el uso del losartan un medicamento para la hipertensión puede reducir las lesiones provocadas por el #COVIDー19 #coronavirus https://t.co/GcWxV3ocNw

Jul 20, 2020 · 1 like · 2,091 followers View post →
AREMIM
@AREMIM4 · X

Tiempo de seroconversión: IgM - 12 días IgG - 14 días No se relacionó con menor detección de ARN viral. No sólo respuesta humoral para combatir #COVID19. Artículo completo. Doi: 10.1002/jmv.25785

Mar 31, 2020 · 1 like · 1 share · 94 followers View post →
Laura Borgese
@L_Borgese · X

Organ-protective Effect of Angiotensin-converting Enzyme 2 and its Effect on the Prognosis of COVID-19. https://t.co/5PvsM6AAmC

Mar 31, 2020 · 1 like · 63 followers View post →
Antonio Lesci
@antoniol95 · X

Organ‐protective Effect of Angiotensin‐converting Enzyme 2 and its Effect on the Prognosis of COVID‐19 https://t.co/ClbN5un7NI

Mar 28, 2020 · 1 like · 23 followers View post →
Eclecticity
@twistopherrobin · X

Journal of Medical Virology: "Organ‐protective effect of angiotensin‐converting enzyme 2 and its effect on the prognosis of COVID‐19" by Hao Cheng, Yan Wang, et al, March 27, 2020: https://t.co/8UbvdbOLHa

Apr 22, 2020 · 3,418 followers View post →

All mentions

Auge Aabye
@AugeAabye · X

Se sigue evaluando si el uso del losartan un medicamento para la hipertensión puede reducir las lesiones provocadas por el #COVIDー19 #coronavirus https://t.co/GcWxV3ocNw

Jul 20, 2020 · 1 like · 2,091 followers View post →
Eclecticity
@twistopherrobin · X

Journal of Medical Virology: "Organ‐protective effect of angiotensin‐converting enzyme 2 and its effect on the prognosis of COVID‐19" by Hao Cheng, Yan Wang, et al, March 27, 2020: https://t.co/8UbvdbOLHa

Apr 22, 2020 · 3,418 followers View post →
Researchphilia
@researchphilia · X

Apr 12, 2020 · 482 followers View post →
Fabricio Reyes
@ReyesB_F · X

Interesante *amilorida* con o sin hidroxicloroquina en pacientes con SARS cov 2. Los ARA II son prometedores en COVID-19. Comment on “Organ‐protective Effect of Angiotensin‐converting Enzyme 2 and its Effect on the Prognosis of COVID‐19” https://t.co/TqHCpz9Ikr

Apr 9, 2020 · 42 followers View post →
Rodrigo F.
@Roy_fig · X

RT @AREMIM4: Tiempo de seroconversión: IgM - 12 días IgG - 14 días No se relacionó con menor detección de ARN viral. No sólo respuesta humo…

Mar 31, 2020 · 1 share · 141 followers View post →
Laura Borgese
@L_Borgese · X

Organ-protective Effect of Angiotensin-converting Enzyme 2 and its Effect on the Prognosis of COVID-19. https://t.co/5PvsM6AAmC

Mar 31, 2020 · 1 like · 63 followers View post →
AREMIM
@AREMIM4 · X

Tiempo de seroconversión: IgM - 12 días IgG - 14 días No se relacionó con menor detección de ARN viral. No sólo respuesta humoral para combatir #COVID19. Artículo completo. Doi: 10.1002/jmv.25785

Mar 31, 2020 · 1 like · 1 share · 94 followers View post →
Mishima Eikan
@eikan_em · X

ACE2発現が高いことがコロナ感染に対していいのか悪いのかはcontroversy. この総説ではACE2善玉説の立場で論述。 加齢で肺ACE2減少、ACEI/ARBによるACE2発現増加はよいことかも、rhACE2投与が治療になるかもと記載。J Med Virol誌 #COVID19 https://t.co/UjAoNob3sn

Mar 30, 2020 · 4 likes · 422 followers View post →
the paper link
@the_paper_link · X

Trend new: *Cheng H* et al (J Med Virol) __Organ-protective Effect of Angiotensin-converting Enzyme 2 and its Effect on the Prognosis of COVID-19__ https://t.co/IZ3TygGWIZ

Mar 30, 2020 · 136 followers View post →
NFTdose
@PaperbirdsH · X

New article: Organ-protective Effect of Angiotensin-converting Enzyme 2 and its Effect on the Prognosis of COVID-19. https://t.co/amRjKlXGd0 #coronavirus #COVID19 #2019ncov

Mar 30, 2020 · 302 followers View post →
Antonio Lesci
@antoniol95 · X

Organ‐protective Effect of Angiotensin‐converting Enzyme 2 and its Effect on the Prognosis of COVID‐19 https://t.co/ClbN5un7NI

Mar 28, 2020 · 1 like · 23 followers View post →