PLoS Biol April 2020 PMID 32243449

BigBrain 3D atlas of cortical layers: Cortical and laminar thickness gradients diverge in sensory and motor cortices.

Konrad Wagstyl, Stéphanie Larocque, Guillem Cucurull, Claude Lepage, Joseph Paul Cohen, Sebastian Bludau, Nicola Palomero-Gallagher, Lindsay B Lewis, Thomas Funck, Hannah Spitzer, Timo Dickscheid, Paul C Fletcher, Adriana Romero, Karl Zilles, Katrin Amunts

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Mentions

64
Peak: 29 in May 2020
across 2 sources since Dec 2019

Extended reach

617,633
potential audience

Total likes

873

Video views

47,462

Mentions per month

Dec 2019 – Aug 2025

Where it's discussed

  • X / Twitter62 posts
  • YouTube2 videos

AI synopsis

What people are saying

Several discussions highlight specific aspects of the BigBrain project, such as its use of deep learning to quantify cortical layers and the correlation of cortical thickness with sensory processing. Terms like 'innovation' and 'transformative' show excitement and the serious consideration of its applicability in neuroscience, indicating that users appreciate the depth and significance of this research.

AgreementStrong agreement

The majority of discussions reflect strong support for the findings presented in the publication.

InterestHigh interest

Participants express high curiosity about the BigBrain project and its implications for neuroscience.

EngagementModerate engagement

While some posts provide basic information, most engage with the research contextually, indicating a moderate level of engagement.

ImpactHigh impact

Commenters perceive the contributions of this atlas as significant in advancing understanding of the human brain.

Abstract in brief

  • The BigBrain project created the first quantitative 3D laminar atlas of the human cerebral cortex, allowing for a detailed analysis of cortical layers based on 20-micrometer resolution data.
  • This atlas overcomes the limitations of previous 2D histological atlases, providing more precise measurements of cortical thickness across both hemispheres.
  • The study revealed distinct thickness gradients in sensory cortices (increasing thickness) and motor cortices (decreasing thickness), highlighting the link between neuron structure and brain function.

Top posts

Most liked on X and Bluesky
Human Brain Project
@HumanBrainProj · X

BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortices "We present the first whole-brain #quantitative 3D laminar atlas of the human #cerebral #cortex." Read our new release: https://t.co/FqUN1Hg2hU https://t.co/S9pas67HUA

May 12, 2020 · 78 likes · 35 shares · 36,866 followers View post →
PLOS Biology
@PLOSBiology · X

Using deep learning to segment the layers of the cerebral cortex, @KonradWagstyl @BigBrainProject &co present the first whole brain quantitative atlas of cortical and laminar structure, providing a bridge between the scales of neuroscience #PLOSBiology https://t.co/tScpP0ndox https://t.co/4Kbhy4ODo5

Apr 6, 2020 · 19 likes · 13 shares · 103,122 followers View post →
PLOS Biology
@PLOSBiology · X

Using deep learning to segment the layers of the cerebral cortex, @KonradWagstyl @BigBrainProject &co present the first whole brain quantitative atlas of cortical and laminar structure, providing a bridge between the scales of neuroscience #PLOSBiology https://t.co/tScpP0ndox https://t.co/OJJgRLMYMt

Apr 6, 2020 · 15 likes · 5 shares · 103,122 followers View post →
Miles Wischnewski - Psyched!
@MilesWischnews1 · X

New video on our channel! a short explanation of the six-layered cerebral cortex: https://t.co/m30AOLyFbB #neuroscience #brain #scicomm

Jun 4, 2023 · 6 likes · 1,252 followers View post →
PLOS Biology
@PLOSBiology · X

Using deep learning to segment the layers of the cerebral cortex, @KonradWagstyl @BigBrainProject &co present the first whole brain quantitative atlas of cortical and laminar structure, providing a bridge between the scales of neuroscience #PLOSBiology https://t.co/tScpP05BZX https://t.co/mFqks8GxSt

Apr 7, 2020 · 4 likes · 1 share · 103,122 followers View post →
@parkvillegeek
@ParkvilleGeek · X

BigBrain 3D atlas of cortical layers: cortical and laminar thickness gradients diverge in sensory and motor cortices | #bioRxiv https://t.co/dHNiyMCPwp https://t.co/sPz4nsdawP

Dec 10, 2019 · 4 likes · 1 share · 2,679 followers View post →

All mentions

Filemón Esteban López Pérez
@ecbky · X

Exploring EBRAINS brain atlases using siibra-explorer https://t.co/yADgEXD2N0 via @YouTube

Aug 2, 2025 · 131 followers View post →
Metsuke (めつけ)
@metsuke · X

Visto en YT: Exploring EBRAINS brain atlases using siibra-explorer https://t.co/QarNrtGYEN

Feb 20, 2024 · 676 followers View post →
Miles Wischnewski - Psyched!
@MilesWischnews1 · X

New video on our channel! a short explanation of the six-layered cerebral cortex: https://t.co/m30AOLyFbB #neuroscience #brain #scicomm

Jun 4, 2023 · 6 likes · 1,252 followers View post →
Fathima Gani R
@fgrsmiles · X

BigBrain 3D atlas of cortical layers: Cortical and laminar thickness gradients diverge in sensory and motor cortice… https://t.co/WPCU0BKv0I

Jun 3, 2022 · 98 followers View post →
Alexandra Badea
@portokalh · X

https://t.co/EOn5Lqz2Zn

Jan 16, 2021 · 955 followers View post →
talking
@TalhaKavak15 · X

RT @turkerkilic: İnsan Konnektom Projesi kapsamında yeni yayınlanan MR verisine göre detaylı insan beyin kortejsiniz 3B atlası yayınlandı.…

Oct 28, 2020 · 9 shares · 31 followers View post →
luis hernan graffe
@hernangraffe · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

Oct 6, 2020 · 35 shares · 3,126 followers View post →
Galia Georgieva
@galiatherapyhub · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 16, 2020 · 35 shares · 13 followers View post →
katja heuer
@katjaQheuer · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 15, 2020 · 35 shares · 3,733 followers View post →
Türker KILIÇ
@turkerkilic · X

RT @turkerkilic: İnsan Konnektom Projesi kapsamında yeni yayınlanan MR verisine göre detaylı insan beyin kortejsiniz 3B atlası yayınlandı.…

May 14, 2020 · 9 shares · 113,531 followers View post →
salvador dell
@salvadordell49 · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 13, 2020 · 35 shares · 15 followers View post →
Peter McColgan
@Peter_Mc_Colgan · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 13, 2020 · 35 shares · 725 followers View post →
CSN lab UvA
@CogSysNeuroSci · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 13, 2020 · 35 shares · 506 followers View post →
4Brain
@UGent4Brain · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 13, 2020 · 35 shares · 186 followers View post →
bryan stallard
@headlocal · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 13, 2020 · 35 shares · 383 followers View post →
Dr.Wumi
@wumiakinlosotu · X

#cerebral #cortex https://t.co/6qfkEYAFD9

May 13, 2020 · 1,325 followers View post →
Proud_Casteist
@Privileged_Chu · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 13, 2020 · 35 shares · 582 followers View post →
British Neuroscience Association
@BritishNeuro · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 13, 2020 · 35 shares · 38,097 followers View post →
Roberto Toro r3rt0@mstdn.social r3rt0.bsky.social
@R3RT0 · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 13, 2020 · 35 shares · 3,836 followers View post →
Neuroinformatics
@HBPNeuroinf · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 13, 2020 · 35 shares · 1,283 followers View post →
CHU-CHUNG HUANG
@CHUCHUNGHUANG · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 12, 2020 · 35 shares · 18 followers View post →
Zoey Isherwood
@zoeyisherwood · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 12, 2020 · 35 shares · 342 followers View post →
Rodrigo Kazu
@DrRodrigoKazu · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 12, 2020 · 35 shares · 198 followers View post →
EstherKuehn
@EstherEKuehn · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 12, 2020 · 35 shares · 475 followers View post →
psiconeuroblog
@psiconeuroblog · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 12, 2020 · 35 shares · 286 followers View post →
Anton Pashkov
@anton_pashkov03 · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 12, 2020 · 35 shares · 1,675 followers View post →
Engineering Studies Journal
@EngrStudies · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 12, 2020 · 35 shares · 600 followers View post →
Marc-Oliver Gewaltig
@gewaltig · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 12, 2020 · 35 shares · 777 followers View post →
Matthieu Thiboust
@mthiboust · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 12, 2020 · 35 shares · 1,111 followers View post →
iPsych
@_iPsych · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 12, 2020 · 35 shares · 25 followers View post →
LIU Dawei, M.D., Ph.D.
@liudawei05329 · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 12, 2020 · 35 shares · 1,175 followers View post →
CUBRIC
@CUBRICcardiff · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 12, 2020 · 35 shares · 3,650 followers View post →
VEDA-SPORTPARK INTER
@med7sportarten · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 12, 2020 · 35 shares · 1,758 followers View post →
HBP Neurorobotics
@HBPNeurorobotic · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 12, 2020 · 35 shares · 1,326 followers View post →
จู
@JMulP · X

RT @HumanBrainProj: BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortice…

May 12, 2020 · 35 shares · 202 followers View post →
Human Brain Project
@HumanBrainProj · X

BigBrain 3D #atlas of #cortical layers: Cortical and laminar thickness gradients diverge in #sensory and #motor cortices "We present the first whole-brain #quantitative 3D laminar atlas of the human #cerebral #cortex." Read our new release: https://t.co/FqUN1Hg2hU https://t.co/S9pas67HUA

May 12, 2020 · 78 likes · 35 shares · 36,866 followers View post →
UCL Discovery
@ucl_discovery · X

Open Access UCL Research: BigBrain 3D atlas of cortical layers: Cortical and laminar thickness gradients diverge in sensory and motor cortices - UCL Discovery https://t.co/eNVbj1H2v7

Apr 22, 2020 · 2,524 followers View post →
Cam
@LailaLisio · X

RT @PLOSBiology: Using deep learning to segment the layers of the cerebral cortex, @KonradWagstyl @BigBrainProject &co present the first wh…

Apr 7, 2020 · 1 share · 3 followers View post →
PLOS Biology
@PLOSBiology · X

Using deep learning to segment the layers of the cerebral cortex, @KonradWagstyl @BigBrainProject &co present the first whole brain quantitative atlas of cortical and laminar structure, providing a bridge between the scales of neuroscience #PLOSBiology https://t.co/tScpP05BZX https://t.co/mFqks8GxSt

Apr 7, 2020 · 4 likes · 1 share · 103,122 followers View post →
Carmen Sandoval-Espinosa, PhD
@car_men_ita · X

RT @PLOSBiology: Using deep learning to segment the layers of the cerebral cortex, @KonradWagstyl @BigBrainProject &co present the first wh…

Apr 6, 2020 · 13 shares · 743 followers View post →
Manuel Sánchez
@ManoloSanchezA · X

RT @PLOSBiology: Using deep learning to segment the layers of the cerebral cortex, @KonradWagstyl @BigBrainProject &co present the first wh…

Apr 6, 2020 · 13 shares · 1,728 followers View post →
Raul Alvarez
@Raul_Alvarez_Pr · X

RT @PLOSBiology: Using deep learning to segment the layers of the cerebral cortex, @KonradWagstyl @BigBrainProject &co present the first wh…

Apr 6, 2020 · 13 shares · 674 followers View post →
PLOS Biology
@PLOSBiology · X

Using deep learning to segment the layers of the cerebral cortex, @KonradWagstyl @BigBrainProject &co present the first whole brain quantitative atlas of cortical and laminar structure, providing a bridge between the scales of neuroscience #PLOSBiology https://t.co/tScpP0ndox https://t.co/4Kbhy4ODo5

Apr 6, 2020 · 19 likes · 13 shares · 103,122 followers View post →
Columbia Stem Cell Initiative (CSCI)
@CSCIColumbia · X

RT @PLOSBiology: Using deep learning to segment the layers of the cerebral cortex, @KonradWagstyl @BigBrainProject &co present the first wh…

Apr 6, 2020 · 5 shares · 1,334 followers View post →
Jonathan A. Michaels
@JonAMichaels · X

RT @PLOSBiology: Using deep learning to segment the layers of the cerebral cortex, @KonradWagstyl @BigBrainProject &co present the first wh…

Apr 6, 2020 · 5 shares · 5,062 followers View post →
Dr Klaatu
@RSprackland · X

RT @PLOSBiology: Using deep learning to segment the layers of the cerebral cortex, @KonradWagstyl @BigBrainProject &co present the first wh…

Apr 6, 2020 · 5 shares · 2,083 followers View post →
PLOS Biology
@PLOSBiology · X

Using deep learning to segment the layers of the cerebral cortex, @KonradWagstyl @BigBrainProject &co present the first whole brain quantitative atlas of cortical and laminar structure, providing a bridge between the scales of neuroscience #PLOSBiology https://t.co/tScpP0ndox https://t.co/OJJgRLMYMt

Apr 6, 2020 · 15 likes · 5 shares · 103,122 followers View post →
yazsam ki
@yazsamki · X

RT @turkerkilic: İnsan Konnektom Projesi kapsamında yeni yayınlanan MR verisine göre detaylı insan beyin kortejsiniz 3B atlası yayınlandı.…

Apr 6, 2020 · 9 shares · 184 followers View post →
Burcu Sakız, PhD
@_burcusan_ · X

RT @turkerkilic: İnsan Konnektom Projesi kapsamında yeni yayınlanan MR verisine göre detaylı insan beyin kortejsiniz 3B atlası yayınlandı.…

Apr 5, 2020 · 9 shares · 2,127 followers View post →
xbeam_01
@xbeam_01 · X

RT @turkerkilic: İnsan Konnektom Projesi kapsamında yeni yayınlanan MR verisine göre detaylı insan beyin kortejsiniz 3B atlası yayınlandı.…

Apr 5, 2020 · 9 shares · 101 followers View post →
AxanLab
@AxanLab · X

RT @turkerkilic: İnsan Konnektom Projesi kapsamında yeni yayınlanan MR verisine göre detaylı insan beyin kortejsiniz 3B atlası yayınlandı.…

Apr 5, 2020 · 9 shares · 93 followers View post →
Ömer F. Altıparmak
@OmfarAl · X

RT @turkerkilic: İnsan Konnektom Projesi kapsamında yeni yayınlanan MR verisine göre detaylı insan beyin kortejsiniz 3B atlası yayınlandı.…

Apr 5, 2020 · 9 shares · 109 followers View post →
NonLocalityGuy
@NonLocalityGuy · X

RT @neurokinetikz: Cortical thickness increased across sensory processing hierarchies, primarily driven by layers III, V, and VI. https:/…

Apr 5, 2020 · 1 share · 1,733 followers View post →
neurokinetikz
@neurokinetikz · X

Cortical thickness increased across sensory processing hierarchies, primarily driven by layers III, V, and VI. https://t.co/xM5Si4Xza1

Apr 5, 2020 · 1 like · 1 share · 459 followers View post →
Rosaura Brisuela @roswitta.bsky.social
@Roswitamind · X

RT @Dr_Alex_Crimi: BigBrain 3DAtlas of cortical layers: Cortical and laminar thickness gradients diverge in sensory & motor cortices by .@…

Apr 4, 2020 · 1 share · 1,283 followers View post →
Alessandro Crimi
@Dr_Alex_Crimi · X

BigBrain 3DAtlas of cortical layers: Cortical and laminar thickness gradients diverge in sensory & motor cortices by .@KonradWagstyl.@gcpreix.@josephpaulcohen.@adri_romsor.@tffunck.@HannahSpitzer1.@dickscheid.@PaulPcf22.@acehigh1952. https://t.co/f46fDgJOBp /n #brain #Neurology https://t.co/ZIBPT5bqtb

Apr 4, 2020 · 2 likes · 1 share · 7,741 followers View post →
Christian Schnell
@NeuroSchnell · X

https://t.co/YtZMW8OMdf

Apr 4, 2020 · 2,232 followers View post →
Dr.Wumi
@wumiakinlosotu · X

This an innovation into the study of cerebral cortical network! https://t.co/fPI97H5ATQ

Apr 4, 2020 · 1,325 followers View post →
Mariano Dominguez
@marianojavierd1 · X

BigBrain 3D atlas of cortical layers: Cortical and laminar thickness gradients diverge in sensory and motor cortices https://t.co/gRI5ywEQlQ #uncategorized #feedly

Apr 3, 2020 · 1,670 followers View post →
Dataemia
@Dataemia · X

BigBrain 3D atlas of cortical layers: Cortical and laminar thickness gradients diverge in sensory and motor cortices - https://t.co/2QnsYfmJyL https://t.co/vInGYXF7Sa

Apr 3, 2020 · 966 followers View post →
Nuclear_doc
@doc_nuclear · X

RT @ParkvilleGeek: BigBrain 3D atlas of cortical layers: cortical and laminar thickness gradients diverge in sensory and motor cortices | #…

Jan 6, 2020 · 1 share · 739 followers View post →
@parkvillegeek
@ParkvilleGeek · X

BigBrain 3D atlas of cortical layers: cortical and laminar thickness gradients diverge in sensory and motor cortices | #bioRxiv https://t.co/dHNiyMCPwp https://t.co/sPz4nsdawP

Dec 10, 2019 · 4 likes · 1 share · 2,679 followers View post →