Eur Respir J May 2020 PMID 32269089

ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19.

Janice M Leung, Chen X Yang, Anthony Tam, Tawimas Shaipanich, Tillie-Louise Hackett, Gurpreet K Singhera, Delbert R Dorscheid, Don D Sin

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Mentions

74
Peak: 39 in Apr 2020
across 5 sources since Mar 2020

Extended reach

285,876
potential audience

Total likes

145

Video views

1,386

Mentions per month

Mar 2020 – Oct 2023

Where it's discussed

  • X / Twitter62 posts
  • News8 articles
  • YouTube2 videos
  • Instagram1 posts
  • Blogs1 articles

AI synopsis

What people are saying

The overall discussions reflect strong agreement, with many posts supporting the study's conclusion that higher ACE-2 levels in smokers and COPD patients increase COVID-19 susceptibility. Posts employ urgent language like 'Good time to stop smoking' and cite notable researchers, which highlights high interest and perceived high impact of the research on public health behaviors and policy, especially around smoking and COVID-19 risk management.

AgreementStrong agreement

Most discussions emphasize the significance of the study, highlighting that increased ACE-2 expression is linked to higher COVID-19 risk in smokers and COPD patients, showing strong support for the findings.

InterestHigh interest

The posts demonstrate high interest by referencing related studies, mechanisms, and public health implications, indicating engagement with the topic’s importance.

EngagementModerate engagement

Many discussions include citations of specific researchers and calls for smoking cessation, suggesting a thoughtful and in-depth engagement, though some posts are more brief and cite the study without elaboration.

ImpactHigh impact

The widespread sharing of links, emphasis on smoking cessation, and discussions connecting ACE-2 levels with COVID-19 severity show that the discourse perceives the study as having substantial health and policy implications.

Abstract in brief

  • ACE2, the receptor used by the COVID-19 virus to enter cells, is found at higher levels in the small airway epithelia of smokers and those with COPD (Chronic Obstructive Pulmonary Disease).
  • This increased expression of ACE2 might make smokers and COPD patients more susceptible to severe COVID-19 infection.
  • The study suggests that understanding ACE2 levels could help in managing and preventing COVID-19 risks in these groups.]

Top posts

Most liked on X and Bluesky
American Thoracic Society (ATS)
@atscommunity · X

ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nckbDAm8b2

Apr 16, 2020 · 20 likes · 15 shares · 42,006 followers View post →
American Thoracic Society (ATS)
@atscommunity · X

ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nckbDAm8b2

Apr 10, 2020 · 13 likes · 9 shares · 42,006 followers View post →
Science in Vancouver
@ScienceVancity · X

A team led by Dr. Don Sin (@donsin4) at @HLIStPauls has shown for the first time that smokers and COPD patients have more ACE-2 protein in the lungs, possibly explaining why these populations have high rates of severe #COVID19 infection. https://t.co/qMCuvyGLna

Apr 20, 2020 · 13 likes · 8 shares · 3,464 followers View post →
Dr. Samir Nusair, MD
@SamirNus · X

ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for #COVID19 #COVID_19. There is increased ACE-2 expression in airways of current (but not former) #smokers and those with #COPD. Good time 4 #smokingcessation https://t.co/M8jYTvkKdc

Apr 9, 2020 · 12 likes · 3 shares · 1,567 followers View post →
medRxiv
@medrxivpreprint · X

ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19 https://t.co/jGqsXGr5ux #medRxiv

Mar 23, 2020 · 5 likes · 17,446 followers View post →
Francis Villatoro
@emulenews · X

On the importance of smoking cessation in reducing the risk: "ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19" https://t.co/t39dH6if2l

Mar 23, 2020 · 3 likes · 1 share · 45,055 followers View post →

All mentions

John Paul
@JohnPau61360651 · X

@ejustin46 @DKlemitz @KappaFannon Also this is being censored becuase...... ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19 https://t.co/58oHBexZLZ https://t.co/hB0gGhPFUC

Oct 14, 2023 · 177 followers View post →
Robowop
@RDagoist · X

@txsalth2o It's funny, they don't like to talk about it anymore, but last year there were plenty of studies showing smoking might help https://t.co/zBsKzwKZDS https://t.co/j4VHFiqIpY https://t.co/vZgknbgP4b

Nov 26, 2021 · 245 followers View post →
georgepapadapol
@georgepapadapol · X

@MinaGagaP:Implicación en #COVIDー19 de la expresión aumentada del receptor ACE2 en vía aérea de sujetos fumadores y pacientes #EPOC:

Sep 8, 2020 · 1 like · 1,253 followers View post →
Ángel Nieto
@angelnieto_ · X

Sobreexpresión de receptores ACE-2, puerta de entrada de #COVID19, en fumadores y en pacientes #EPOC. ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19 https://t.co/uROJc9W7Q6

Jun 21, 2020 · 1 like · 2,334 followers View post →
Julien Fort
@JulienFort4 · X

@jojo_goeland @Senadu_ @LeiR3aG @docprimum Lol, non les profs Amoura et Changeux pensent qu aucune étude n a été faite dans le monde sur le tabac et le Covid , nuance Cette étude dit que fumer accroît la sévérité chez les patients contaminés par le Covid https://t.co/MfQmO19TNk https://t.co/CxcTXr4ciX

May 30, 2020 · 727 followers View post →
Lung EOPH_papers
@LungEOPH · X

ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19. https://t.co/KGhhrrSIc7 https://t.co/AKKKgdODDF

May 21, 2020 · 49 followers View post →
Angel Azpeitia
@AngelAzpeitia · X

ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19 | European Respiratory Society https://t.co/L5kC6hdsnW, see more https://t.co/DYNr6PkPQa

May 20, 2020 · 1 like · 1,475 followers View post →
Interasma
@Interasma · X

Top story: ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19 | European Respiratory Society https://t.co/ODZI8wUVtj, see more https://t.co/CpGiFuOOYd

May 20, 2020 · 2,448 followers View post →
World Allergy Organization
@worldallergy · X

Top story: ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19 | European Respiratory Society https://t.co/ZsDmFidLAa, see more https://t.co/yY235TM04T

May 20, 2020 · 1 like · 9,979 followers View post →
SLaai
@SocLatAlergia · X

RT @Aller_MD: Top story: ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19 | European…

May 19, 2020 · 4 shares · 1,772 followers View post →
Fundación Libra
@FUNDACIONLIBRA · X

RT @Aller_MD: Top story: ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19 | European…

May 19, 2020 · 4 shares · 415 followers View post →
Interasma
@Interasma · X

RT @Aller_MD: Top story: ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19 | European…

May 19, 2020 · 4 shares · 2,448 followers View post →
Juan C Ivancevich MD
@Aller_MD · X

Top story: ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19 | European Respiratory Society https://t.co/JsmwGI9qrH, see more https://t.co/jgCeENQuZt

May 19, 2020 · 2 likes · 4 shares · 7,482 followers View post →
Illingworth Library
@IllingworthInfo · X

ACE-2 expression in the small airway epithelia of smokers and COPD… https://t.co/4Yhwjm6ZwU #eprompt #respire

May 15, 2020 · 381 followers View post →
@SoMe4MV
@some4mv · X

RT @some4mv: ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19 https://t.co/wnkuq4ptZT #SoMe4MV from Leung, J. M., Yang, C. X., Tam, A., Shaipanich, T., Hackett, T.-L., Singhera, G. K., Dorscheid, D. R., Sin, D. D.#ERSpublica…

May 14, 2020 · 6,302 followers View post →
@SoMe4MV
@some4mv · X

ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19 https://t.co/wnkuq4ptZT #SoMe4MV from Leung, J. M., Yang, C. X., Tam, A., Shaipanich, T., Hackett, T.-L., Singhera, G. K., Dorscheid, D. R., Sin, D. D.#ERSpublications

May 14, 2020 · 6,302 followers View post →
Canadian Thoracic Society
@CTS_SCT · X

RT @ScienceVancity: A team led by Dr. Don Sin (@donsin4) at @HLIStPauls has shown for the first time that smokers and COPD patients have mo…

Apr 20, 2020 · 8 shares · 1,284 followers View post →
Astrid Levelt
@AstridLevelt · X

RT @ScienceVancity: A team led by Dr. Don Sin (@donsin4) at @HLIStPauls has shown for the first time that smokers and COPD patients have mo…

Apr 20, 2020 · 8 shares · 457 followers View post →
Adrian Png
@fuzziebrain · X

RT @ScienceVancity: A team led by Dr. Don Sin (@donsin4) at @HLIStPauls has shown for the first time that smokers and COPD patients have mo…

Apr 20, 2020 · 8 shares · 1,365 followers View post →
Providence Research
@PHCResearch · X

RT @ScienceVancity: A team led by Dr. Don Sin (@donsin4) at @HLIStPauls has shown for the first time that smokers and COPD patients have mo…

Apr 20, 2020 · 8 shares · 756 followers View post →
Science in Vancouver
@ScienceVancity · X

A team led by Dr. Don Sin (@donsin4) at @HLIStPauls has shown for the first time that smokers and COPD patients have more ACE-2 protein in the lungs, possibly explaining why these populations have high rates of severe #COVID19 infection. https://t.co/qMCuvyGLna

Apr 20, 2020 · 13 likes · 8 shares · 3,464 followers View post →
Alfopab
@alfopab · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 16, 2020 · 15 shares · 969 followers View post →
Kuang-Yu Chen
@KuangYu_Chen · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 16, 2020 · 15 shares · 100 followers View post →
Almansour
@malmansour81 · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 16, 2020 · 15 shares · 211 followers View post →
Jessica Spencer Castner
@DrCastner · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 16, 2020 · 15 shares · 967 followers View post →
Isa Musa Wasagu
@IsahMW · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 16, 2020 · 15 shares · 351 followers View post →
Arantxa M
@mefi81 · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 16, 2020 · 15 shares · 118 followers View post →
Alejandro Videla
@ajv67 · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 16, 2020 · 15 shares · 2,529 followers View post →
Margaret Pisani
@PisaniMAP · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 16, 2020 · 15 shares · 2,048 followers View post →
COPD_research
@COPD_research · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 16, 2020 · 15 shares · 3,924 followers View post →
Chiara Catellani
@nerd_thing · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 16, 2020 · 15 shares · 10 followers View post →
Sushma Cribbs
@SushmaCribbs · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 16, 2020 · 15 shares · 573 followers View post →
mess
@Specula99412503 · X

ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19 https://t.co/cM4lalo2Hx

Apr 16, 2020 · 1 like · 106 followers View post →
Zafer Gökkaya
@drzafergokkaya · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 16, 2020 · 15 shares · 124 followers View post →
Tasneem Alee
@Al_Tasneemz · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 16, 2020 · 15 shares · 83 followers View post →
American Thoracic Society (ATS)
@atscommunity · X

ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nckbDAm8b2

Apr 16, 2020 · 20 likes · 15 shares · 42,006 followers View post →
Magnum
@watchfuldefend · X

ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19 | European Respiratory Society https://t.co/qS68AjvXZe

Apr 13, 2020 · 3,672 followers View post →
Animal Sentinels
@PETS_for_Pets · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 11, 2020 · 9 shares · 117 followers View post →
libertad fraternidad igualdad democracia.
@rodolfovikingo · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 11, 2020 · 9 shares · 185 followers View post →
COPD_research
@COPD_research · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 10, 2020 · 9 shares · 3,924 followers View post →
Leslie Vargas-Ramírez
@lilo1278 · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 10, 2020 · 9 shares · 2,474 followers View post →
Tanapong
@exodear · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 10, 2020 · 9 shares · 25 followers View post →
Bernardodeshki
@bernardodeshki · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 10, 2020 · 9 shares · 30 followers View post →
Carolina Glz Fuentes
@karolas_smile · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 10, 2020 · 9 shares · 299 followers View post →
Cheyenne
@BreathAndMind · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 10, 2020 · 9 shares · 406 followers View post →
Alejandro Videla
@ajv67 · X

RT @atscommunity: ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nck…

Apr 10, 2020 · 9 shares · 2,529 followers View post →
American Thoracic Society (ATS)
@atscommunity · X

ACE-2 expression in the small airway epithelia of smokers and #COPD patients: Implications for #COVID19: https://t.co/nckbDAm8b2

Apr 10, 2020 · 13 likes · 9 shares · 42,006 followers View post →
Cheryl Amber Dotson
@GODZILLASLAYS65 · X

ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19 | European Respiratory Society https://t.co/D9PDN1BeOr

Apr 10, 2020 · 1,089 followers View post →
Erik Hulzebos
@DrErikHollywood · X

ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19 https://t.co/ZbD5CH6XI4

Apr 10, 2020 · 118 followers View post →
Havva Sayar Kalkan
@hawasayar · X

ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19 | European Respiratory Society https://t.co/LZkyW2taLi

Apr 10, 2020 · 210 followers View post →
oSaMa
@oZaMa30 · X

RT @SamirNus: ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for #COVID19 #COVID_19. There is i…

Apr 10, 2020 · 3 shares · 1,447 followers View post →
Leslie Vargas-Ramírez
@lilo1278 · X

RT @SamirNus: ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for #COVID19 #COVID_19. There is i…

Apr 9, 2020 · 3 shares · 2,474 followers View post →
Herbert Sammler von Daten
@herby210269 · X

Rauchen kann das Risiko für Covid-19 erhöhen Smoking Helps Open Gateway to Coronavirus Infection, Study Shows https://t.co/MaFi9c7ko0 ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19 https://t.co/YTSALzo5tZ

Apr 9, 2020 · 1 like · 393 followers View post →
Carlos Andrés Celis-Preciado
@pulmonology101 · X

RT @SamirNus: ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for #COVID19 #COVID_19. There is i…

Apr 9, 2020 · 3 shares · 4,347 followers View post →
Dr. Samir Nusair, MD
@SamirNus · X

ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for #COVID19 #COVID_19. There is increased ACE-2 expression in airways of current (but not former) #smokers and those with #COPD. Good time 4 #smokingcessation https://t.co/M8jYTvkKdc

Apr 9, 2020 · 12 likes · 3 shares · 1,567 followers View post →
David Barbic
@DavidBarbic · X

ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19 (preprint). Good time to stop smoking... ⁦@CHEOSNews⁩ ⁦@BCEmergMedNtwrk⁩ ⁦@helpstpauls⁩ ⁦@Providence_Hlth⁩ https://t.co/Qf5vyzefYM

Mar 25, 2020 · 1 like · 586 followers View post →
Outbreak Science
@outbreaksci · X

Contribute a rapid review or request one for "ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implicati..." (https://t.co/TQkdvZO9tg). "Add" or "Request" w/DOI (10.1101/2020.03.18.20038455) at https://t.co/RnurTL3DyM @outbreaksci @PREreview_

Mar 25, 2020 · 1,372 followers View post →
Outbreak Science
@outbreaksci · X

New #COVID19 preprint: ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19 https://t.co/TQkdvZO9tg

Mar 25, 2020 · 1,372 followers View post →
Pau Morey
@morey_pau · X

RT @emulenews: MedRxiv version of the paper "ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for…

Mar 23, 2020 · 1 share · 216 followers View post →
Francis Villatoro
@emulenews · X

MedRxiv version of the paper "ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19" https://t.co/t39dH6if2l https://t.co/UBfliIOwOZ

Mar 23, 2020 · 1 share · 45,055 followers View post →
Francis Villatoro
@emulenews · X

On the importance of smoking cessation in reducing the risk: "ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19" https://t.co/t39dH6if2l

Mar 23, 2020 · 3 likes · 1 share · 45,055 followers View post →
medRxiv
@medrxivpreprint · X

ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19 https://t.co/jGqsXGr5ux #medRxiv

Mar 23, 2020 · 5 likes · 17,446 followers View post →
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