May 2020 PMID 32323740

Treadmill exercise promotes neurogenesis and myelin repair via upregulating Wnt/β‑catenin signaling pathways in the juvenile brain following focal cerebral ischemia/reperfusion.

Jingyan Cheng, Weimin Shen, Lingqin Jin, Juanjuan Pan, Yan Zhou, Guoyuan Pan, Qingfeng Xie, Quan Hu, Shamin Wu, Hongmei Zhang, Xiang Chen

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Peak: 3 in Mar 2021

across 2 sources since Mar 2021

Extended reach

13,908

potential audience

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Mentions per month

Mar 2021 – Dec 2021

Where it's discussed

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YouTube2 videos

AI synopsis

What people are saying

The discussions highlight the significance of treadmill exercise in promoting brain repair, with comments calling it 'fascinating' and noting the biological mechanisms involved. The tone is curious yet supportive, emphasizing interest in the scientific details and potential therapeutic implications.

AgreementModerate agreement

Most discussions acknowledge the significance of the research, indicating general agreement with the findings that treadmill exercise aids brain recovery after ischemia.

InterestHigh interest

The discussions express high interest, with words like 'fascinating' and emphasizing the potential of treadmill exercise in neural repair.

EngagementModerate engagement

Participants show moderate engagement, referencing specific mechanisms like Wnt/β-catenin signaling and its role in neurogenesis and myelin repair.

ImpactModerate impact

While the tone suggests awareness of the research's importance, the discussions focus more on recognition than on exploring broader societal or clinical impacts.

Abstract in brief

Treadmill exercise enhances neurogenesis and myelin repair in juvenile rats after ischemic stroke by activating the Wnt/β-catenin signaling pathway, leading to improved neurological recovery and reduced brain damage.
The study used various methods to confirm this, including staining techniques, electron microscopy, and molecular analysis, showing increased levels of key proteins like Wnt3a, β-catenin, BDNF, and MBP with exercise.
The inhibition of the Wnt/β-catenin pathway with XAV939 diminished these benefits, indicating that this pathway is crucial for exercise-induced neuroprotection and neural repair after stroke.]

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Fitness Therapy: Neuroscience Professional Learner

@LaCourCouture · X

Another interesting find: Treadmill exercise promotes neurogenesis and myelin repair via upregulating Wnt/β‑catenin signaling pathways in the juvenile brain following focal cerebral ischemia/reperfusion https://t.co/QAfTIzARGt

Dec 8, 2021 · 446 followers View post →

Fitness Therapy: Neuroscience Professional Learner

@LaCourCouture · X

Fascinating. Treadmill association with neurogenesis and myelin repair. https://t.co/ROCcNUx5Nn

Apr 18, 2021 · 1 like · 446 followers View post →

POPLINE

@POPLINE_org · X

RT @EurekaMag: Treadmill exercise promotes neurogenesis and myelin repair via upregulating Wnt/β‑catenin signaling pathways in the juvenile…

Mar 20, 2021 · 2 shares · 5,269 followers View post →

Science Alerts

@Science_Alerts · X

RT @EurekaMag: Treadmill exercise promotes neurogenesis and myelin repair via upregulating Wnt/β‑catenin signaling pathways in the juvenile…

Mar 20, 2021 · 2 shares · 1,241 followers View post →

EurekaMag

@EurekaMag · X

Mar 20, 2021 · 2 shares · 6,472 followers View post →