Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/gOsvk2De50
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir.
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May 2020 – Aug 2021Where it's discussed
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X / Twitter93 posts
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News28 articles
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Facebook11 posts
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Blogs9 articles
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YouTube3 videos
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Reddit3 posts
AI synopsis
What people are saying
In the discussions, posts like 'This is incredible' and inquiries about how remdesivir works demonstrate a shared curiosity and excitement around the research. The frequent mentions of remdesivir's mechanism of action suggest that users find the information relevant and vital. Additionally, comments referring to specific scientific concepts, such as 'energy-dependent hydrogen bonds,' indicate a desire for a deeper understanding of the subject, contributing to a positive engagement by utilizing an informative and enthusiastic tone.
The majority of posts highlight the therapeutic implications of remdesivir and agree on its importance in combating COVID-19.
There is a high level of interest in understanding how remdesivir works at the molecular level, as many users inquire about its mechanism.
Certain posts show deeper engagement through discussions of technical aspects, such as the role of remdesivir in blocking RNA synthesis and its potential in drug design.
Many users express the belief that the findings could significantly affect future antiviral drug development.
Abstract in brief
- The study investigates the structure of the SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) both without and with the antiviral drug remdesivir.
- Remdesivir is shown to be incorporated into the viral RNA strand and stops the replication process at a critical point, helping us understand how it works against the virus.
- The findings of this research could guide future drug design efforts aimed at treating COVID-19 by targeting viral replication mechanisms.
Top posts
Most liked on X and BlueskyStructural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/CsKpCVvTIC
Report: https://t.co/Asi3hmul6d (OPEN) "Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir" by Wanchao Yin, Chunyou Mao, Xiaodong Luan, Dan-Dan Shen, Qingya Shen, Haixia Su, Xiaoxi Wang, Fulai Zhou, Wenfeng Z…https://t.co/UBIxRYI2iT
以前からオンラインでは出ていたけれど Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/bkoUcBKdTU
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/GMghUOoyJ3
This is Remdesivir Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/p491HHydWV
All mentions
Understanding Remdesivir's Mechanism Against SARS-CoV-2
Remdesivir is the first medicine to demonstrate efficacy in combatting SARS-CoV-2. In this video, we delve into how remdesivir inhibits viral replication at the molecular level, offering insights that could inform…
Understanding Remdesivir's Role in COVID-19 Treatment
Since its emergence in December 2019, the world has been dealing with COVID-19, officially declared a pandemic by the WHO. This video explores Remdesivir, the first FDA-approved antiviral for COVID-19, detailing its…
Mechanism of Remdesivir - a drug to fight COVID-19
#RaviVisvesvarayaSharadaPrasad https://t.co/oVh419OhWA Remdesivir chống lại COVID-19 như thế nào? Dạy Kèm Quy Nhơn Remdesivir fights COVID-19. How does it work? (Remdesivir chống lại COVID-19 như thế nào?) https://t.co/HZzK5hFkOj
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/Vbdhv0esXd To gain mechanistic insights and to know therapeutic options available for COVID-19: https://t.co/6ySOYVgCcD https://t.co/ZGNRi4CquW
Remdesivir fights COVID-19. How does it work? In our video, we probe remdesivir’s mechanism of action to understand how it inhibits viral replication at the molecular level. https://t.co/7zRXfQSowU https://t.co/GAmY4CtCql
@davestewart4444 @AlumiLynn @TinFoilAwards @DoctorBou @emartinez78987 @BGLTHMND @JNAlexandratos @kidoctr @Rectitude20 @USoA34805717 @LoriSan29894021 @WeAreVacInjured @FTC @doritmi @mcfunny He clearly does not understand energy-dependent hydrogen bonds and phosphorylation which are the "Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir" https://t.co/pPuwWgthVM
Remdesivir mimics an RNA nucleotide building block and is covalently linked to the replicating RNA, which blocks further synthesis of RNA. Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/h0zjMeYkak
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/IPStaZQvSX
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/zc24A1XKLk
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/CdAtgRaW1a
EIDD-2801 - Can we improve over remdesivir. This structure opens up in silico design. Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/zrhi26ks2w
RT @uranus_2: レムデシビルが新型コロナウイルスのRNA複製を阻害するメカニズム。Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remde…
以前からオンラインでは出ていたけれど Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/bkoUcBKdTU
レムデシビルが新型コロナウイルスのRNA複製を阻害するメカニズム。Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/ortPK9VrYp
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/V6vkRpTQgZ
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/1pYAnGf4nL The pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global crisis. R... https://t.co/NuZSQ6lGip
RT @OzlemEquilsMD: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir | Science https://t.co…
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/jDd0FH2el9
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir | Science https://t.co/BaCKry3vhH
Read to understand why it takes so long to create an effective #COVID19 #vaccine. Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by #remdesivir - science.abc1560.full.pdf https://t.co/BwjKHAfuWb #ScienceMatters
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/nnpNuKdySA The replication of SARS-CoV-2 requires the viral RNA-dependent RNA polymerase (RdRp), a target of the antiviral drug, Remdesivir.
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/5dU5eTRLy1 『レムデシビルは、最初に複製された塩基対でプライマー鎖に共有結合的に組み込まれ、鎖伸長を終了させる』
Nice study investigating remdesivir's mechanism of action: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/ojwVPfkWhr
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/2mG0VFV9NU
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/QBwdkGaMhx
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/8KL3MFVz4c
RT @T_NABEBUGYOU: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/GEz3soiiOU
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/GEz3soiiOU
RT @Biomaven: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/pA7WjRWdkF
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/pA7WjRWdkF
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by Remdesivir https://t.co/V4tF40Qe2C @ACEPNow @CDCDirector @AliRaja_MD @ScottGottliebMD @jimcramer @DrEricDing @srrezaie @emcrit @EmergencyDocs
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/igFT43DFIi. How remdesivir blocks SARS-CoV-2 in the Structural manner.
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/V2THxnjPDM
The complex structure reveals that the partial double-stranded RNA template is inserted into the central channel of the RdRp where Remdesivir is covalently incorporated into the primer strand at the first replicated base pair & terminates chain elongation https://t.co/E7AzUBykQd
Trend up+81: *Yin W* et al (Science) __Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir__ https://t.co/NZgsoQ6iEl
RT @cflagospharma: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by Remdesivir https://t.co/8RZ3d0D11…
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by Remdesivir https://t.co/8RZ3d0D11a Structure https://t.co/bCh39Y2fAE
RT @WinssingerLab: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/XKHjPdXnjk
RT @cryoEM_Papers: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/gOsvk2De50
S/ Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. https://t.co/tlwXhGIxVP
RT @tothur: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir | Science https://t.co/ByW8FE…
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir | Science https://t.co/ByW8FE6lEk
中国の科学者がレンデシビルによるSARS-CoV-2阻害の構造的基礎を解明 Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/0zBJh6s2Hm
RT @grawoig: Report: https://t.co/Asi3hmul6d (OPEN) "Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by…
RT @cryoEM_Papers: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/gOsvk2De50
RT @grawoig: Report: https://t.co/Asi3hmul6d (OPEN) "Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by…
RT @grawoig: Report: https://t.co/Asi3hmul6d (OPEN) "Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by…
Report: https://t.co/Asi3hmul6d (OPEN) "Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir" by Wanchao Yin, Chunyou Mao, Xiaodong Luan, Dan-Dan Shen, Qingya Shen, Haixia Su, Xiaoxi Wang, Fulai Zhou, Wenfeng Z…https://t.co/UBIxRYI2iT
RT @qtnet: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/A8rzaB0yWD
RT @cryoEM_Papers: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/gOsvk2De50
RT @masha_niv: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/hdHbiYeets
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/ETwHceG1O6
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/PQ9No8tLaa #tweeted
RT @vjimenezyuste: This is Remdesivir Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir htt…
RT @WinssingerLab: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/XKHjPdXnjk
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/hrW60RCJwO
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/FWSq2Fq6vE
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/hdHbiYeets
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/2HSHPoY3lS
RT @cryoEM_Papers: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/gOsvk2De50
RT @WinssingerLab: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/XKHjPdXnjk
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/L9e4lHJYBT
This is Remdesivir Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/p491HHydWV
RT @cryoEM_Papers: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/gOsvk2De50
RT @PhDilkersaygili: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/GMghUOo…
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/uNvEzGKhwy
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/GMghUOoyJ3
RT @ShabihShakeel: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/9TVLYm5kSl
Top @RNomics #tweeted story: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir | Science https://t.co/epzg60YYAV, see more https://t.co/mx2YzvfCax
RT @WinssingerLab: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/XKHjPdXnjk
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/Il4U0ejqRH
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/8aiCAyhNZS
RT @CostaT_Lab: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/CsKpCVvTIC
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by #remdesivir | #RNAPol #SARSCoV2 #structure https://t.co/GaNKc3mtyq
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/B80dBUgEol
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/A8rzaB0yWD
RT @cryoEM_Papers: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/gOsvk2De50
RT @Fm7: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/1SqJ6wZRNo
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/1SqJ6wZRNo
@nebre8ed @IngrahamAngle @GileadSciences Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/cGqPXz27St
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/cGqPXz27St
RT @cryoEM_Papers: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/gOsvk2De50
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir | Science https://t.co/WWDnygolQ3
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/FxEI8LoMCb
RT @CostaT_Lab: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/CsKpCVvTIC
RT @cryoEM_Papers: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/gOsvk2De50
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/CsKpCVvTIC
RT @cryoEM_Papers: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/gOsvk2De50
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/rcPTiFsPGN
RT @cryoEM_Papers: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/gOsvk2De50
Remdesivir disrupts Covid-19 SARS-CoV-2 RdRp complex per the paper below. I suggest these RNA complements be tried as per the picture below. Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/K6H44WRpaZ https://t.co/Drj9mM8gLr
RT @cryoEM_Papers: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/gOsvk2De50
RT @ShabihShakeel: Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/9TVLYm5kSl
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/gOsvk2De50
This is incredible. Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir https://t.co/cJlqpTEKfs