The discussions demonstrate strong interest in the genetic aspects of aging, with posts explicitly mentioning unique gene variants and their possible role in prolonging lifespan, indicating a mix of curiosity and support. The tone ranges from casual remarks about dogs living long lives to more technical comments on gene transcription and immune response, reflecting moderate engagement with some depth, but with an overall consensus that this research could influence future aging studies.
AgreementModerate agreement
Most discussions acknowledge the significance of genetic research on longevity, especially highlighting the uniqueness of ancient dogs' genomes.
InterestHigh interest
Posts show high curiosity about the genetic findings and their implications for aging and potential parallels in humans.
EngagementModerate engagement
Many posts reference specific genetic findings and the study's methodology, indicating a moderate level of detailed engagement.
ImpactModerate impact
While there's excitement about the potential of such research, many discussions are preliminary and suggest further research is needed before broad impact is realized.
Abstract in brief
This study investigates the genetic factors behind extreme aging by analyzing the whole-genome sequences of two very old dogs, aged 22 and 27 years, which is much longer than the average dog lifespan.
Researchers identified over 800,000 new genetic variations (SNPs), many of which are in non-coding regions, and some found in genes related to immune response, nervous system, and gene regulation, suggesting these areas may influence longevity.
The findings point to specific genetic pathways that could be linked to extreme lifespan risk and highlight the potential importance of gene transcription regulation, which warrants further research to confirm its role in aging in both dogs and humans.
And now I can add “Methuselah Dogs” to my list of odd but potentially useful ideas for storytelling…
https://t.co/MOtAwPKt9E
Feb 10, 2021 · 16 likes · 684,626 followersView post →
EK
Eniko Kubinyi
@KubinyiEniko · X
As a follow-up on our recent study*, we aim at collecting DNA from dogs older than 20 years. Do you happen to know one such as the famous Augie? Please contact me. https://t.co/XMhQ3LWR9E
*Genetics of #Methuselah dogs: https://t.co/p8D22zzKiz
Jun 28, 2020 · 15 likes · 10 shares · 1,574 followersView post →
FP
Family Dog Project
@FamDogProject · X
Our new research identified gene variants unique to two Methuselah dogs (aged 22 and 27 years) which could not be found in 850 dogs of average age. The genome of the oldest old “Methuselahs” is enriched with gene variants that can elongate lifespan.
https://t.co/Tc66fbZjc0
#DNADay Did you know that @FamDogProject examined DNA of two old “Methuselah” dogs (22 & 27yrs!) and identified unique gene variants which didn't exist in DNA of 850 average dogs suggesting they have DNA enriched with genes that can elongate lifspan
DNA collection and cognitive tests on a 27-year-old Methuselah dog. This study investigates the genetic factors behind extreme aging by analyzing the whole-genome sequences of very old dogs, identifying variations…
This study investigates the genetic foundations of extreme aging by analyzing the whole-genome sequences of two exceptionally old dogs, aged 22 and 27 years, revealing new genetic variations and pathways linked to…
This study investigates the genetic factors behind extreme aging by analyzing the whole-genome sequences of two very old dogs, aged 22 and 27 years, which is much longer than the average dog lifespan. Over 800,000 new…
This study investigates the genetic factors behind extreme aging by analyzing the whole-genome sequences of two very old dogs, aged 22 and 27 years, which is much longer than the average dog lifespan. The findings…
We're taking part in the @RoyalSocBio #BiologyWeek2020! Today they're looking at healthy ageing
Oct 5, 2020 · 5 likes · 3 shares · 3,961 followersView post →
CR
CREEB Roehampton
@CREEBroehampton · X
RT @KubinyiEniko: As a follow-up on our recent study*, we aim at collecting DNA from dogs older than 20 years. Do you happen to know one su…
Jun 29, 2020 · 10 shares · 705 followersView post →
KT
Kristiina Torp
@KristiinaTorp · X
RT @KubinyiEniko: As a follow-up on our recent study*, we aim at collecting DNA from dogs older than 20 years. Do you happen to know one su…
Jun 29, 2020 · 10 shares · 152 followersView post →
AD
Andrea Sommese, Ph.D.
@andrea_sommese · X
RT @KubinyiEniko: As a follow-up on our recent study*, we aim at collecting DNA from dogs older than 20 years. Do you happen to know one su…
Jun 28, 2020 · 10 shares · 1,294 followersView post →
NW
Naomi Harvey PhD #WearAMask
@Naomi_D_Harvey · X
RT @KubinyiEniko: As a follow-up on our recent study*, we aim at collecting DNA from dogs older than 20 years. Do you happen to know one su…
Jun 28, 2020 · 10 shares · 16,747 followersView post →
HG
Holly Root-Gutteridge
@holly_howls · X
RT @KubinyiEniko: As a follow-up on our recent study*, we aim at collecting DNA from dogs older than 20 years. Do you happen to know one su…
Jun 28, 2020 · 10 shares · 1,013 followersView post →
DS
Dog Cognition SE
@DogCognitionSE · X
RT @KubinyiEniko: As a follow-up on our recent study*, we aim at collecting DNA from dogs older than 20 years. Do you happen to know one su…
Jun 28, 2020 · 10 shares · 7,003 followersView post →
DP
Dr Zazie Todd (PhD)
@CompAnimalPsych · X
RT @KubinyiEniko: As a follow-up on our recent study*, we aim at collecting DNA from dogs older than 20 years. Do you happen to know one su…
Jun 28, 2020 · 10 shares · 13,165 followersView post →
EK
Eniko Kubinyi
@KubinyiEniko · X
As a follow-up on our recent study*, we aim at collecting DNA from dogs older than 20 years. Do you happen to know one such as the famous Augie? Please contact me. https://t.co/XMhQ3LWR9E
*Genetics of #Methuselah dogs: https://t.co/p8D22zzKiz
Jun 28, 2020 · 15 likes · 10 shares · 1,574 followersView post →
FP
Family Dog Project
@FamDogProject · X
FDP research about the genetics of extremely old dogs (22&27†) sin the Canine Corner blog by Stanley Coren
https://t.co/4sA73MuRIB
original study: https://t.co/Tc66fbHHNq
Jun 2, 2020 · 1 share · 4,394 followersView post →
SD
Stefano Cattaneo DVM
@Albinovet · X
a preliminary study to investigate the genetic background of #longevity based on whole-genome sequence data of 2 Methuselah dogs. Most novel mutations were related to gene transcription/translation, to immune response& the nervous system in general https://t.co/3NCtWb70CZ https://t.co/ZcEezj1Usd
#DNADay Did you know that @FamDogProject examined DNA of two old “Methuselah” dogs (22 & 27yrs!) and identified unique gene variants which didn't exist in DNA of 850 average dogs suggesting they have DNA enriched with genes that can elongate lifspan
New Research: A Preliminary Study to Investigate the Genetic Background of Longevity Based on Whole-Genome Sequence Data of Two Methuselah Dogs: Aging is the largest risk factor in many diseases and mortality alike. As the elderly population is… https://t.co/myL3HgzNlQ #Genetics
Apr 25, 2020 · 1 like · 1 share · 5,391 followersView post →
EV
Etolia· Etología Vet
@Etologiamalaga · X
A Preliminary Study to Investigate the Genetic Background of Longevity Based on Whole-Genome Sequence Data of Two Methuselah Dogs
https://t.co/Qo8yM5D42m
Our new research identified gene variants unique to two Methuselah dogs (aged 22 and 27 years) which could not be found in 850 dogs of average age. The genome of the oldest old “Methuselahs” is enriched with gene variants that can elongate lifespan.
https://t.co/Tc66fbZjc0
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