10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell death, which then leads to neurodegenerative diseases https://t.co/dlRp8Z8poJ.
Going the Extra (Synaptic) Mile: Excitotoxicity as the Road Toward Neurodegenerative Diseases.
Mentions
Extended reach
Total likes
Video views
Mentions per month
Apr 2020 – Apr 2025Where it's discussed
-
X / Twitter62 posts
-
YouTube13 videos
-
News2 articles
AI synopsis
What people are saying
The overall tone reflects strong agreement, especially where posters emphasize excitotoxicity's role in neurodegenerative diseases, with phrases like 'great comprehensive review' and calls to 'look deeper into these mechanisms.' The use of technical terms such as 'ROS,' 'neuroplasticity,' and 'synaptic failure' shows active engagement, while the acknowledgment of excitotoxicity as a contributor rather than the sole cause underscores its relevance in ongoing research discussions.
Most posts acknowledge the importance of excitotoxicity and its link to neurodegenerative diseases, showing general agreement with the publication's focus.
Posts display high interest by highlighting the complexity of neurotoxic processes and praising the review as comprehensive.
Discussions include references to molecular mechanisms like calcium control and mitochondrial dysfunction, indicating moderate engagement.
The shared content and praise suggest the publication could influence ongoing neuroscience research and understanding of neurodegeneration.
Abstract in brief
- Excitotoxicity occurs when excessive glutamate activates brain receptors, leading to neuron damage and death, with astrocytes normally regulating glutamate levels to prevent this.
- The process involves disruptions in glutamate and calcium metabolism, malfunction of transporters and receptors (especially NMDARs), and is linked to mitochondrial dysfunction, oxidative stress, and neuronal injury.
- This phenomenon plays a central role in neurodegenerative diseases such as Alzheimer's, ALS, and epilepsy, with overactivation of NMDARs causing harmful calcium influx and subsequent cellular damage.
Top posts
Most liked on X and BlueskyNew Research: Going the Extra (Synaptic) Mile: Excitotoxicity as the Road Toward Neurodegenerative Diseases: Excitotoxicity is a phenomenon that describes the toxic actions of excitatory neurotransmitters, primarily glutamate, where the… https://t.co/ZoaAwpB3Y3 #neuroscience
10/ La excitotoxicidad del glutamato puede iniciar "una cascada de neurotoxicidad", lo que lleva a la pérdida de la función neuronal y la muerte celular, lo que luego conduce a enfermedades neurodegenerativas https://t.co/1HPIfZboJx.
Our last review on excitotoxicity in neurodegenerative diseases @FrontNeurosci Going the Extra (Synaptic) Mile: Excitotoxicity as the Road Toward Neurodegenerative Diseases https://t.co/pJjxXBE7Xf
https://t.co/wA31m0TFbO https://t.co/zRzaaG5P5p
Neurodegeneration Neurons lose calcium control. Mitochondria can’t buffer it → excitotoxicity, ROS, synaptic failure. Note: this is not the sole cause, but a contributor. PMID: 35078537, https://t.co/T1IW30m2P6
All mentions
Glutamate and Its Impact on Neurodegenerative Diseases
Research reports highlight the harmful effects of glutamate as a neurotransmitter in the brain. Excitotoxicity is linked to neurodegenerative diseases, affecting cognitive functions and more. This video delves into…
Effects of MSG on Neurotransmission and Neurodegenerative Diseases
This video discusses the harmful effects of monosodium glutamate (MSG) as revealed in research. Studies highlight how glutamate can lead to excitotoxicity, contributing to neurological and psychiatric disorders. Learn…
Impact of Monosodium Glutamate on Neurological Health
Research reports detail the harmful effects of Monosodium Glutamate (MSG) as a neurotransmitter in the brain. This video explores excitotoxicity and its implications for neurodegenerative diseases, psychiatric…
Risks of MSG: Impacts on Brain Health and Neurodegenerative Diseases
This video explores the harmful effects of MSG on brain health, including its role as a neurotransmitter. It delves into research findings on excitotoxicity and its implications for neurodegenerative diseases, offering…
Understanding the Risks of Monosodium Glutamate (MSG)
The MSG in extract has shorter amino chains, allowing for greater absorption than natural food variants. Research shows the link between excitotoxicity and neurodegenerative diseases, indicating potential negative…
Impact of MSG on Neurological Health and Disease
The MSG in extract is absorbed more readily and in greater amounts than the longer chain variant in natural foods. This video explores the role of glutamate in neurotransmission, its connection to excitotoxicity, and…
Foods to Avoid MSG and Their Impact on Brain Health
In this video, I choose certain food places to avoid MSG that kills brain cells and can cause headaches. I discuss how high-glycemic foods and caffeine affect skin aging and health. Additionally, I share a list of…
Impact of MSG on Neurotransmission and Health
Research reports highlight the harmful effects of MSG on neurotransmission and its link to neurodegenerative diseases. This video discusses excitotoxicity and the implications for neurological and psychiatric disorders…
Understanding MSG and Its Effects on Neurotransmission
The MSG in extract features shorter amino chains that are absorbed more effectively than those in natural foods. This video delves into the implications of glutamate as a neurotransmitter and its potential role in…
Impact of MSG on Brain Health and Neurodegenerative Diseases
This video explores the effects of MSG on health, particularly its link to neurodegenerative diseases. We examine how glutamate functions as a neurotransmitter and the research surrounding its potential risks, including…
Effects of Monosodium Glutamate on Liver and Heart Health in Rats
Consumption of Monosodium Glutamate (MSG) at varying doses causes liver and heart damage in male rats, characterized by increased weight, lipid abnormalities, inflammation, and tissue damage. The study indicates…
Neurotoxic Effects of Monosodium Glutamate on Brain and Organ Health
Consumption of Monosodium Glutamate (MSG) at varying doses causes liver and heart damage in male rats, characterized by increased weight, lipid abnormalities, inflammation, and tissue damage. The study suggests MSG may…
Impact of Monosodium Glutamate on Liver and Heart Health in Rats
Research shows that MSG consumption at various doses causes liver and heart damage in male rats, including increases in weight, lipid abnormalities, and tissue inflammation. Excessive or hidden intake may have adverse…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
Neurodegeneration Neurons lose calcium control. Mitochondria can’t buffer it → excitotoxicity, ROS, synaptic failure. Note: this is not the sole cause, but a contributor. PMID: 35078537, https://t.co/T1IW30m2P6
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
https://t.co/3hIKOtRnCG --- behold the beauty of #excitotoxicity and #neuroplasticity #neuroscience
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @Watchandwait123: 10/ La excitotoxicidad del glutamato puede iniciar "una cascada de neurotoxicidad", lo que lleva a la pérdida de la fu…
RT @IrelandStandUp: https://t.co/wA31m0TFbO
RT @Watchandwait123: 10/ La excitotoxicidad del glutamato puede iniciar "una cascada de neurotoxicidad", lo que lleva a la pérdida de la fu…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
https://t.co/wA31m0TFbO https://t.co/zRzaaG5P5p
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
10/ La excitotoxicidad del glutamato puede iniciar "una cascada de neurotoxicidad", lo que lleva a la pérdida de la función neuronal y la muerte celular, lo que luego conduce a enfermedades neurodegenerativas https://t.co/1HPIfZboJx.
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
RT @JanuaryDoNoHarm: 10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell…
10/ Glutamate excitotoxicity can start "a cascade of neurotoxicity,” leading to the loss of neuronal function and cell death, which then leads to neurodegenerative diseases https://t.co/dlRp8Z8poJ.
RT @SandraHVaz1: Our last review on excitotoxicity in neurodegenerative diseases @FrontNeurosci Going the Extra (Synaptic) Mile: Excitotox…
RT @SandraHVaz1: Our last review on excitotoxicity in neurodegenerative diseases @FrontNeurosci Going the Extra (Synaptic) Mile: Excitotox…
RT @SandraHVaz1: Our last review on excitotoxicity in neurodegenerative diseases @FrontNeurosci Going the Extra (Synaptic) Mile: Excitotox…
Our last review on excitotoxicity in neurodegenerative diseases @FrontNeurosci Going the Extra (Synaptic) Mile: Excitotoxicity as the Road Toward Neurodegenerative Diseases https://t.co/pJjxXBE7Xf
https://t.co/23avcz46si A great comprehensive review on excitotoxicity!
RT @FrontNeurosci: New Research: Going the Extra (Synaptic) Mile: Excitotoxicity as the Road Toward Neurodegenerative Diseases: Excitotoxic…
RT @FrontNeurosci: New Research: Going the Extra (Synaptic) Mile: Excitotoxicity as the Road Toward Neurodegenerative Diseases: Excitotoxic…
RT @FrontNeurosci: New Research: Going the Extra (Synaptic) Mile: Excitotoxicity as the Road Toward Neurodegenerative Diseases: Excitotoxic…
New Research: Going the Extra (Synaptic) Mile: Excitotoxicity as the Road Toward Neurodegenerative Diseases: Excitotoxicity is a phenomenon that describes the toxic actions of excitatory neurotransmitters, primarily glutamate, where the… https://t.co/ZoaAwpB3Y3 #neuroscience
Congratulations Sandra on your newly published @FrontiersIn article: https://t.co/lkmOmAbANZ
JL
FN
EV
SV
IU
GM
M
PR
J
DV
DN
ID
F
B
JS
JW
GZ
JS
AW
EB
I
PT
TL
GS
PS
ZW
TT
H
CT
LM
M
B
CW
C
M
I
VW
L
W
OI
AS
P
R
M
PH
Q
PX
A
T
U
WL
EG
VH
JO
LS
MN
IL
AE
TF