Front Immunol March 2021 PMID 32411126

Research Advances in How the cGAS-STING Pathway Controls the Cellular Inflammatory Response.

Dongshan Wan, Wei Jiang, Junwei Hao

Mentions

8
Peak: 4 in Sep 2021
across 2 sources since May 2020

Extended reach

36,407
potential audience

Total likes

36

Video views

350

Mentions per month

May 2020 – Jun 2024

Where it's discussed

  • X / Twitter6 posts
  • YouTube2 videos

AI synopsis

What people are saying

Comments demonstrate strong agreement with the research's importance, especially in relation to innovative therapies and vaccine strategies, evidenced by phrases like 'crucial pathway,' 'therapeutic applications,' and 'cancer immunotherapy.' The tone reflects both curiosity and optimism about its clinical relevance, with some posts engaging by linking the pathway to real-world benefits.

AgreementStrong agreement

Most discussions support the importance of the cGAS-STING pathway in immune regulation and potential therapies, showing strong consensus.

InterestHigh interest

The discussions highlight excitement and curiosity about the pathway's role in diseases like cancer and infections, indicating high interest.

EngagementModerate engagement

Some posts reference the research's implications for vaccine development and cancer immunotherapy, suggesting moderate engagement with detailed context.

ImpactHigh impact

Multiple mentions relate to the pathway's significance in developing new treatments and vaccines, emphasizing its high potential impact.

Abstract in brief

  • The cGAS-STING pathway, involving the DNA sensor cGAS and the stimulator STING, is crucial for immune surveillance by promoting inflammatory responses like type I interferons and other processes such as autophagy, cell survival, and senescence.
  • This pathway interacts with other innate immune mechanisms and plays a significant role in regulating responses to infections, inflammatory diseases, and cancer, making it a promising target for therapeutic interventions.
  • Recent research advances and previous studies help us better understand how the cGAS-STING pathway functions and is modulated in various disease states, highlighting its potential for future clinical applications.

Top posts

Most liked on X and Bluesky
Christie Laura Grace
@_HeartofGrace_ · X

2/ s://doi.org/10.3390/ijms23020716 Wan, Research advances in how the cGAS–STING pathway controls the cellular inflammatory response, Front Immunol, № 11, с. 615 *s://doi.org/10.3389/fimmu.2020.00615 Jiang, cGAS–STING, an important pathway in cancer immunotherapy, J Hematol

Jun 1, 2024 · 7 likes · 2 shares · 27,063 followers View post →
G.
@ElAlam_Vnz · X

RT @_HeartofGrace_: 2/ s://doi.org/10.3390/ijms23020716 Wan, Research advances in how the cGAS–STING pathway controls the cellular inflamma…

Jun 1, 2024 · 2 shares · 4,309 followers View post →
El Atenuador.
@EduardoLuger · X

RT @_HeartofGrace_: 2/ s://doi.org/10.3390/ijms23020716 Wan, Research advances in how the cGAS–STING pathway controls the cellular inflamma…

Jun 2, 2024 · 2 shares · 2,389 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Research Advances in How the cGAS-STING Pathway Controls the Cellular Inflammatory Response. https://t.co/WyJlBQZZrb

May 17, 2020 · 2,241 followers View post →
Binay K. Sahoo, Ph.D.
@sahoobinay22 · X

World's 1st #DNAVaccine for #COVID-19: #ZYCOV-D (Part 1/3)I What is DNA Va... https://t.co/cXQvrnytU3 via @YouTube #vaccination #VaccineMandate #VaccinePassport #vaccine #zyduscadila https://t.co/ujqUHteuQQ

Sep 16, 2021 · 22 followers View post →
Binay K. Sahoo, Ph.D.
@sahoobinay22 · X

#DNAVaccine #vaccine #COVID19 #India #madeinindia https://t.co/cXQvrnytU3

Sep 13, 2021 · 22 followers View post →

All mentions

El Atenuador.
@EduardoLuger · X

RT @_HeartofGrace_: 2/ s://doi.org/10.3390/ijms23020716 Wan, Research advances in how the cGAS–STING pathway controls the cellular inflamma…

Jun 2, 2024 · 2 shares · 2,389 followers View post →
G.
@ElAlam_Vnz · X

RT @_HeartofGrace_: 2/ s://doi.org/10.3390/ijms23020716 Wan, Research advances in how the cGAS–STING pathway controls the cellular inflamma…

Jun 1, 2024 · 2 shares · 4,309 followers View post →
Christie Laura Grace
@_HeartofGrace_ · X

2/ s://doi.org/10.3390/ijms23020716 Wan, Research advances in how the cGAS–STING pathway controls the cellular inflammatory response, Front Immunol, № 11, с. 615 *s://doi.org/10.3389/fimmu.2020.00615 Jiang, cGAS–STING, an important pathway in cancer immunotherapy, J Hematol

Jun 1, 2024 · 7 likes · 2 shares · 27,063 followers View post →
Binay K. Sahoo, Ph.D.
@sahoobinay22 · X

World's 1st #DNAVaccine for #COVID-19: #ZYCOV-D (Part 1/3)I What is DNA Va... https://t.co/cXQvrnytU3 via @YouTube #vaccination #VaccineMandate #VaccinePassport #vaccine #zyduscadila https://t.co/ujqUHteuQQ

Sep 16, 2021 · 22 followers View post →
Binay K. Sahoo, Ph.D.
@sahoobinay22 · X

#DNAVaccine #vaccine #COVID19 #India #madeinindia https://t.co/cXQvrnytU3

Sep 13, 2021 · 22 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Research Advances in How the cGAS-STING Pathway Controls the Cellular Inflammatory Response. https://t.co/WyJlBQZZrb

May 17, 2020 · 2,241 followers View post →