January 2021 PMID 32433801

Modulation of skin androgenesis and sebum production by a dermocosmetic formulation.

Elisete Isabel Crocco, Evellin Barbosa Bonifácio, Gustavo Facchini, Gustavo Henrique da Silva, Michelle Sabrina da Silva, Ana Lucia Tabarini Alves Pinheiro, Paula Voltarelli Franco Avelar, Samara Eberlin

Mentions

6
Peak: 2 in May 2020
across 3 sources since May 2020

Extended reach

32,184
potential audience

Total likes

507

Video views

23,907

Mentions per month

May 2020 – Dec 2025

Where it's discussed

  • X / Twitter2 posts
  • YouTube2 videos
  • News2 articles

AI synopsis

What people are saying

Discussions highlight the potential of the formulation to control hormonal activity related to acne, with phrases like 'could be a game-changer' indicating optimism. The tone is generally informative, referencing the biochemical effects like reduced lipid production and androgen levels, which underscores their recognition of the research's significance and real-world implications.

AgreementModerate agreement

Most discussions acknowledge the potential benefits of the dermocosmetic formulation in modulating sebum production, indicating general support for the research findings.

InterestModerate interest

Participants show moderate curiosity, with some expressing interest in how the formulation could be a non-toxic alternative for acne management.

EngagementNeutral engagement

Engagement appears moderate, as some comments reference specific mechanisms or ask questions, but many others remain superficial.

ImpactModerate impact

The overall tone suggests that the publication could influence future acne treatments, though the discussions stop short of wide-scale endorsement or critical evaluation.

Abstract in brief

  • The study explores a cosmetic formulation called DTRW that may help prevent acne by targeting the overproduction of sebum, which is driven by excess androgens like testosterone and DHT in the skin.
  • When human sebocytes (skin oil-producing cells) are treated with DTRW, there is a significant reduction in lipid and fatty acid production, as well as decreases in key androgenic substances, suggesting it can modulate hormonal activity linked to acne.
  • The findings suggest that DTRW could be an effective, non-toxic option for managing acne by preventing sebaceous gland dysregulation and reducing excessive sebum production, which are primary factors in acne development.]

Top posts

Most liked on X and Bluesky
Microbiome Articles
@microbe_article · X

Modulation of skin androgenesis and sebum production by dermocosmetic formulation. - Crocco EI et al. - https://t.co/CDP8tDxbwz #microbiome

May 21, 2020 · 1 like · 7,153 followers View post →
Symbiosis papers
@Symbiosispapers · X

Modulation of skin androgenesis and sebum production by dermocosmetic formulation. https://t.co/iVaxMTFCAL

May 21, 2020 · 1,104 followers View post →

All mentions

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Haircafe · Jun 19, 2023 23,901 views
Symbiosis papers
@Symbiosispapers · X

Modulation of skin androgenesis and sebum production by dermocosmetic formulation. https://t.co/iVaxMTFCAL

May 21, 2020 · 1,104 followers View post →
Microbiome Articles
@microbe_article · X

Modulation of skin androgenesis and sebum production by dermocosmetic formulation. - Crocco EI et al. - https://t.co/CDP8tDxbwz #microbiome

May 21, 2020 · 1 like · 7,153 followers View post →
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