PubHawk
Am J Psychiatry December 2020 PMID 32456505

Parietal-Prefrontal Feedforward Connectivity in Association With Schizophrenia Genetic Risk and Delusions.

Danielle L B Greenman, Michelle A N La, Shefali Shah, Qiang Chen, Karen F Berman, Daniel R Weinberger, Hao Yang Tan

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Mentions

27
Peak: 9 in May 2020
across 2 sources since Oct 2019

Extended reach

288,735
potential audience

Total likes

47

Video views

147

Mentions per month

Oct 2019 – Jan 2023

Where it's discussed

  • X / Twitter25 posts
  • YouTube2 videos

AI synopsis

What people are saying

Discussions exemplify support through phrases like 'great work' and highlight interest via mentions of advances in brain connectivity and machine learning applications. Engagement is shown by detailed references to Bayesian models and connectivity findings, indicating deep involvement, while impact is acknowledged through the potential for improved prediction models and understanding genetic risk, emphasizing its importance for future research.

AgreementModerate agreement

Most discussions express support or recognition of the study’s findings, highlighting its significance and endorsing its contribution to schizophrenia research.

InterestHigh interest

The social discussions demonstrate high interest, with mentions of how the research advances understanding of brain connectivity and its implications for delusions.

EngagementHigh engagement

Many posts delve into methodological details, mention key researchers, and respond to interpretations, showing active engagement.

ImpactModerate impact

The community perceives the research as impactful, especially with references to its potential for improving predictions and understanding the neural basis of schizophrenia.

Abstract in brief

  • The study investigates how deficits in feedforward communication between parietal and prefrontal brain regions, measured through fMRI, are linked to delusional thinking and genetic risk for schizophrenia.
  • Patients with schizophrenia, especially those with delusions, show reduced parietal-prefrontal connectivity during working memory tasks involving context updating, and this connectivity is further affected by genetic risk factors.
  • Using machine learning models, the researchers can predict individual differences in connectivity and relate deviations from these predictions to the severity of delusions in patients.]
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Top posts

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Raphaël Béné
@neuroraf · X

Bayesian Dysconnections https://t.co/XvXeJScIot : Karl Friston's comment on "Parietal-Prefrontal Feedforward Connectivity in Association With Schizophrenia Genetic Risk and Delusions" https://t.co/knm9lkaiw9 https://t.co/7YHxhmwpQS

May 24, 2021 · 18 likes · 8 shares · 3,258 followers View post →
Journals of The American Psychiatric Association
@APAPubJournals · X

Machine learning models incorporating brain communication data across healthy subjects and schizophrenia patients could improve predictions of individual patients’ symptom severity. Learn More: https://t.co/9ApvNELYtO https://t.co/SGMbFg3aUB

May 28, 2020 · 9 likes · 5 shares · 11,606 followers View post →
USC Master's in NeuroImaging and Informatics: NIIN
@USCNIIN · X

Congrats to NIIN alum, Danielle (Borrajo) Greenman ('17) on her new 1st author paper from her work @LieberInstitute! In patients with #schizophrenia, the authors related brain functional connectivity to delusions & genetic risk for schizophrenia. Paper: https://t.co/rhhXeMgp2Y https://t.co/NnPqwxVvsZ

Jun 24, 2020 · 9 likes · 2 shares · 729 followers View post →
Ali Saffet Gonul
@saffetgonul · X

tonight, we discussed "Parietal-Prefrontal Feedforward Connectivity in Association With Schizophrenia Genetic Risk and Delusions" by Greenman et al. Great work, great article @Dr_Weinberger https://t.co/LmuP3lBpmF

Jul 7, 2020 · 5 likes · 585 followers View post →
Shoei
@shoei05 · X

”妄想形成の概念は、後頭葉から前頭前野にかけての（feedforward）情報の更新に障害があることが示唆されている。その結果、ワーキングメモリ内の新しい情報の統合が機能不全に陥り、最終的には慣れ親しんだ過去の信念を更新することができなくなる。” https://t.co/KA8w99cWw7

May 28, 2020 · 2 likes · 2 shares · 4,382 followers View post →
bioRxiv Neuroscience
@biorxiv_neursci · X

Parietal prefrontal feedforward connectivity in association with schizophrenia genetic risk and delusions https://t.co/uUdFaRfIko #biorxiv_neursci

Oct 11, 2019 · 1 like · 1 share · 60,684 followers View post →

All mentions

Shoei05_メモbot
@shoei05_bot · X

”妄想形成の概念は、後頭葉から前頭前野にかけての（feedforward）情報の更新に障害があることが示唆されている。その結果、ワーキングメモリ内の新しい情報の統合が機能不全に陥り、最終的には慣れ親しんだ過去の信念を更新することができなくなる。” https://t.co/eykvyHIkui

Jan 31, 2023 · 1 like · 290 followers View post →
Shoei05_メモbot
@shoei05_bot · X

”妄想形成の概念は、後頭葉から前頭前野にかけての（feedforward）情報の更新に障害があることが示唆されている。その結果、ワーキングメモリ内の新しい情報の統合が機能不全に陥り、最終的には慣れ親しんだ過去の信念を更新することができなくなる。” https://t.co/eykvyHIkui

Sep 10, 2022 · 1 like · 290 followers View post →
Shoei05_メモbot
@shoei05_bot · X

”妄想形成の概念は、後頭葉から前頭前野にかけての（feedforward）情報の更新に障害があることが示唆されている。その結果、ワーキングメモリ内の新しい情報の統合が機能不全に陥り、最終的には慣れ親しんだ過去の信念を更新することができなくなる。” https://t.co/eykvyHIkui

Apr 30, 2022 · 290 followers View post →
Miriam Alcántara
@Miriam5ht · X

RT @neuroraf: Bayesian Dysconnections https://t.co/XvXeJScIot : Karl Friston's comment on "Parietal-Prefrontal Feedforward Connectivity in…

May 24, 2021 · 8 shares · 414 followers View post →
Goran Dzingalasevic
@Gorandz · X

RT @neuroraf: Bayesian Dysconnections https://t.co/XvXeJScIot : Karl Friston's comment on "Parietal-Prefrontal Feedforward Connectivity in…

May 24, 2021 · 8 shares · 473 followers View post →
Germán AP (赫尔曼)
@Hipergerman · X

RT @neuroraf: Bayesian Dysconnections https://t.co/XvXeJScIot : Karl Friston's comment on "Parietal-Prefrontal Feedforward Connectivity in…

May 24, 2021 · 8 shares · 1,841 followers View post →
CLaE
@leafs_s · X

RT @neuroraf: Bayesian Dysconnections https://t.co/XvXeJScIot : Karl Friston's comment on "Parietal-Prefrontal Feedforward Connectivity in…

May 24, 2021 · 8 shares · 28,697 followers View post →
Psychiatrip⚠️
@Psychiatrip · X

RT @neuroraf: Bayesian Dysconnections https://t.co/XvXeJScIot : Karl Friston's comment on "Parietal-Prefrontal Feedforward Connectivity in…

May 24, 2021 · 8 shares · 292 followers View post →
Raphaël Béné
@neuroraf · X

Bayesian Dysconnections https://t.co/XvXeJScIot : Karl Friston's comment on "Parietal-Prefrontal Feedforward Connectivity in Association With Schizophrenia Genetic Risk and Delusions" https://t.co/knm9lkaiw9 https://t.co/7YHxhmwpQS

May 24, 2021 · 18 likes · 8 shares · 3,258 followers View post →
Journals of The American Psychiatric Association
@APAPubJournals · X

In our December Editor Spotlight video, Deputy Editor Danny Pine reviews studies on feedforward parietal-prefrontal information updating in schizophrenia and on thalamic structural abnormalities in psychosis. https://t.co/kTVhc5iCPB

Dec 23, 2020 · 1 like · 11,606 followers View post →
Ali Saffet Gonul
@saffetgonul · X

tonight, we discussed "Parietal-Prefrontal Feedforward Connectivity in Association With Schizophrenia Genetic Risk and Delusions" by Greenman et al. Great work, great article @Dr_Weinberger https://t.co/LmuP3lBpmF

Jul 7, 2020 · 5 likes · 585 followers View post →
Lieber Institute
@LieberInstitute · X

RT @USCNIIN: Congrats to NIIN alum, Danielle (Borrajo) Greenman ('17) on her new 1st author paper from her work @LieberInstitute! In patien…

Jun 24, 2020 · 2 shares · 1,548 followers View post →
USC Master's in NeuroImaging and Informatics: NIIN
@USCNIIN · X

Congrats to NIIN alum, Danielle (Borrajo) Greenman ('17) on her new 1st author paper from her work @LieberInstitute! In patients with #schizophrenia, the authors related brain functional connectivity to delusions & genetic risk for schizophrenia. Paper: https://t.co/rhhXeMgp2Y https://t.co/NnPqwxVvsZ

Jun 24, 2020 · 9 likes · 2 shares · 729 followers View post →
ふみ
@snitori · X

RT @shoei05: ”妄想形成の概念は、後頭葉から前頭前野にかけての（feedforward）情報の更新に障害があることが示唆されている。その結果、ワーキングメモリ内の新しい情報の統合が機能不全に陥り、最終的には慣れ親しんだ過去の信念を更新することができなくなる。” ht…

May 29, 2020 · 2 shares · 3,626 followers View post →
Maite Garolera
@maitegarolera · X

Parietal-Prefrontal Feedforward Connectivity in Association With Schizophrenia Genetic Risk and Delusions https://t.co/QeshGcp80I

May 29, 2020 · 816 followers View post →
Marcela Cisneros
@DocMarcelaCO · X

RT @APAPubJournals: Machine learning models incorporating brain communication data across healthy subjects and schizophrenia patients could…

May 28, 2020 · 5 shares · 268 followers View post →
helen Gómez
@hg131 · X

RT @APAPubJournals: Machine learning models incorporating brain communication data across healthy subjects and schizophrenia patients could…

May 28, 2020 · 5 shares · 177 followers View post →
Samuele Cortese
@CorteseSamuele · X

RT @APAPubJournals: Machine learning models incorporating brain communication data across healthy subjects and schizophrenia patients could…

May 28, 2020 · 5 shares · 4,030 followers View post →
Machine Learning Bot
@ML_Tweet_Bot · X

RT @APAPubJournals: Machine learning models incorporating brain communication data across healthy subjects and schizophrenia patients could…

May 28, 2020 · 5 shares · 10,157 followers View post →
Journals of The American Psychiatric Association
@APAPubJournals · X

Machine learning models incorporating brain communication data across healthy subjects and schizophrenia patients could improve predictions of individual patients’ symptom severity. Learn More: https://t.co/9ApvNELYtO https://t.co/SGMbFg3aUB

May 28, 2020 · 9 likes · 5 shares · 11,606 followers View post →
KMSleepy
@KMSleepy · X

RT @shoei05: ”妄想形成の概念は、後頭葉から前頭前野にかけての（feedforward）情報の更新に障害があることが示唆されている。その結果、ワーキングメモリ内の新しい情報の統合が機能不全に陥り、最終的には慣れ親しんだ過去の信念を更新することができなくなる。” ht…

May 28, 2020 · 2 shares · 2,379 followers View post →
Shoei
@shoei05 · X

”妄想形成の概念は、後頭葉から前頭前野にかけての（feedforward）情報の更新に障害があることが示唆されている。その結果、ワーキングメモリ内の新しい情報の統合が機能不全に陥り、最終的には慣れ親しんだ過去の信念を更新することができなくなる。” https://t.co/KA8w99cWw7

May 28, 2020 · 2 likes · 2 shares · 4,382 followers View post →
Paul Anastasiades
@P_Anastasiades · X

RT @biorxiv_neursci: Parietal prefrontal feedforward connectivity in association with schizophrenia genetic risk and delusions https://t.c…

Oct 11, 2019 · 1 share · 1,562 followers View post →
bioRxiv Neuroscience
@biorxiv_neursci · X

Parietal prefrontal feedforward connectivity in association with schizophrenia genetic risk and delusions https://t.co/uUdFaRfIko #biorxiv_neursci

Oct 11, 2019 · 1 like · 1 share · 60,684 followers View post →
bioRxiv
@biorxivpreprint · X

Parietal prefrontal feedforward connectivity in association with schizophrenia genetic risk and delusions https://t.co/b1I3AFxwUN #bioRxiv

Oct 11, 2019 · 138,418 followers View post →