Learn tumor evolution from passenger mutations, Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer https://t.co/Cp3rjJVeNh
Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer.
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Mar 2019 – Sep 2023Where it's discussed
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X / Twitter14 posts
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YouTube2 videos
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What people are saying
The discussions reflect a positive reception emphasizing the novel insights into mutational processes using network-based approaches, with words like 'elucidate' and hashtags indicating a focus on bioinformatics and bioRxiv as platforms for significant scientific advancements. The tone suggests appreciation for the research’s contribution to understanding breast cancer mutations and pathways.
Most discussions recognize the value of network-based methods in revealing mutational differences in breast cancer, indicating general agreement on the significance of the research.
The discussions show interest mostly through references to technical aspects and the potential of these approaches, though some posts are quite brief.
Several participants delve into methodological implications, discussing how the approach sheds light on mutation pathways, demonstrating deep engagement.
The emphasis on understanding mutation mechanisms and the multiple mentions of potential for influence suggest moderate to high perceived impact.
Abstract in brief
- The study explores how different mutational processes in breast cancer, like APOBEC activity and clocklike signatures, can be distinguished based on genetic and expression data using a network-based approach.
- It investigates which biological pathways are linked to these mutational signatures and whether genetic alterations in these pathways drive specific mutational patterns.
- The findings reveal that the APOBEC-related mutations and age-related signatures are caused by different mechanisms, with some mutations related to cell cycle activity and others not, highlighting the diverse origins of these mutational signatures.
Top posts
Most liked on X and BlueskyNetwork-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer. https://t.co/ykWlXpTxxf
Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer https://t.co/6HdFp39a8c #biorxiv_bioinfo
Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer. https://t.co/ykWlXpTxxf
Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer. https://t.co/TnoS2AJJba
Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer https://t.co/RuBx7r4gJC #bioRxiv
All mentions
Understanding Mutational Signatures in Breast Cancer Using Network Approaches
The study explores how different mutational processes in breast cancer can be distinguished based on genetic and expression data using a network-based approach. It investigates biological pathways linked to these…
Understanding Mutational Signatures in Breast Cancer Through Network Analysis
This video explores how different mutational processes in breast cancer, like APOBEC activity and clocklike signatures, can be distinguished based on genetic and expression data using a network-based approach.
TP: can see the interaction between mutation and molecular pathways re: breast cancer - see https://t.co/31vY5KROxj #NetBio #ISMB2022
Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer. https://t.co/ykWlXpTxxf
Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer. https://t.co/ykWlXpTxxf
Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer. https://t.co/ykWlXpTxxf
Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer. https://t.co/ykWlXpTxxf
Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer. https://t.co/ykWlXpTxxf
Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer. https://t.co/ykWlXpTxxf
Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer. https://t.co/TnoS2AJJba
Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer https://t.co/UxeLMXbIBf
Learn tumor evolution from passenger mutations, Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer https://t.co/Cp3rjJVeNh
Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer https://t.co/BaTfCcWsjM
#bioRxiv Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer #bioinfo https://t.co/BBFEIhu5ne
Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer https://t.co/6HdFp39a8c #biorxiv_bioinfo
Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer https://t.co/RuBx7r4gJC #bioRxiv