Psychother Psychosom August 2021 PMID 32492688

Prior Therapeutic Experiences, Not Expectation Ratings, Predict Placebo Effects: An Experimental Study in Chronic Pain and Healthy Participants.

Luana Colloca, Titilola Akintola, Nathaniel R Haycock, Maxie Blasini, Sharon Thomas, Jane Phillips, Nicole Corsi, Lieven A Schenk, Yang Wang

Mentions

19
Peak: 14 in Jun 2020
across 3 sources since Jun 2020

Extended reach

43,763
potential audience

Total likes

28

Video views

3

Mentions per month

Jun 2020 – Oct 2025

Where it's discussed

  • X / Twitter15 posts
  • YouTube2 videos
  • News2 articles

AI synopsis

What people are saying

The discussions reveal strong alignment with the study's message that prior experiences matter more than expectations, with references to how placebo effects in conditions like TMD are driven by past therapeutic encounters. Words like 'robust' and mentions of support from organizations like NIDCR highlight the significance and perceived impact of these findings, fostering active engagement among students interested in pain management and placebo research.

AgreementModerate agreement

Most discussions agree with the study’s emphasis on the importance of prior therapeutic experiences over expectations in predicting placebo effects.

InterestHigh interest

The topic appears highly engaging, as indicated by mentions of the study’s implications and references to clinical relevance.

EngagementModerate engagement

Participants show active engagement by referencing specific findings, such as the role of past experiences in TMD and comparisons to medication effects.

ImpactModerate impact

The discussions suggest recognition of the study's potential to influence clinical practices and future research directions.

Abstract in brief

  • This study examined how prior therapeutic experiences, rather than expectations, influence placebo effects in both chronic pain and healthy individuals, finding that past experiences play a key role in response, regardless of expectations.
  • Researchers used tailored pain stimuli and tested placebo responses in a lab setting, discovering that placebo effects were similar across groups and mainly driven by conditioning from previous experiences rather than what participants expected.
  • The findings suggest that understanding a patient's therapeutic history is more important than expectation ratings in predicting placebo responses, which has implications for designing better clinical trials and treatment approaches for chronic pain.

Top posts

Most liked on X and Bluesky
Luana Colloca
@Colloca_Luana · X

Supported by @NIDCR we demonstrated that Placebo effects in TMD are robust, not mediated by expectation ratings, directly linked to prior therapeutic experiences with an NNT of 1.88 in TMD comparable to anticonvulsants and opioids. https://t.co/ZnFJyXMLih @Colloca_Lab @TMDNoMore https://t.co/f5Sljst2Yb

Jun 4, 2020 · 18 likes · 8 shares · 1,164 followers View post →
FISAL
@FisalFisio · X

Jun 15, 2020 · 7 likes · 2 shares · 47 followers View post →
Matt Jones
@Mattjones0203 · X

Prior Therapeutic Experiences, Not Expectation Ratings, Predict Placebo Effects: An Experimental Study in Chronic Pain and Healthy Participants https://t.co/A1aWeOiQPj

Jun 4, 2020 · 2 likes · 1,282 followers View post →
内科医たけお☝ からだと心のクリニック院長
@NaikaiTakeo · X

期待評価ではなく、以前の治療経験はプラセボ効果を予測する:慢性的な痛みと健康な参加者の実験的研究 Prior Therapeutic Experiences, Not Expectation Ratings, Predict Placebo Effects: An Experimental Study in Chronic P… https://t.co/tAzM6dNME3 #あとで読む

Jun 8, 2020 · 1 like · 7,358 followers View post →
ɹǝʇlnoԀ pıʌɐᗡ
@Retlouping · X

RT @Colloca_Luana: Supported by @NIDCR we demonstrated that Placebo effects in TMD are robust, not mediated by expectation ratings, directl…

Jun 4, 2020 · 8 shares · 26,291 followers View post →
Giacomo Rossettini
@GiacomoRoss86 · X

RT @Colloca_Luana: Supported by @NIDCR we demonstrated that Placebo effects in TMD are robust, not mediated by expectation ratings, directl…

Jun 4, 2020 · 8 shares · 2,881 followers View post →

All mentions

鳩71⋈
@fs7112 · X

プラセボといえば、これとても参考になる。 » Prior Therapeutic Experiences, Not Expectation Ratings, Predict Placebo Effects: An Experimental Study in Chronic Pain and Healthy Participants | Psychotherapy and Psychosomatics | Karger Publishers https://t.co/10P8eIWKTO

May 19, 2023 · 559 followers View post →
Maite Goicoechea
@Goicomaite · X

RT @FisalFisio:

Jun 15, 2020 · 2 shares · 1,673 followers View post →
Sònia Colomo
@soniscs · X

RT @FisalFisio:

Jun 15, 2020 · 2 shares · 115 followers View post →
FISAL
@FisalFisio · X

Jun 15, 2020 · 7 likes · 2 shares · 47 followers View post →
内科医たけお☝ からだと心のクリニック院長
@NaikaiTakeo · X

期待評価ではなく、以前の治療経験はプラセボ効果を予測する:慢性的な痛みと健康な参加者の実験的研究 Prior Therapeutic Experiences, Not Expectation Ratings, Predict Placebo Effects: An Experimental Study in Chronic P… https://t.co/tAzM6dNME3 #あとで読む

Jun 8, 2020 · 1 like · 7,358 followers View post →
analgesia.com.mx
@AnalgesiaMx · X

RT @Colloca_Luana: Supported by @NIDCR we demonstrated that Placebo effects in TMD are robust, not mediated by expectation ratings, directl…

Jun 7, 2020 · 8 shares · 41 followers View post →
Luciano da Silva
@luciano_lss · X

RT @Colloca_Luana: Supported by @NIDCR we demonstrated that Placebo effects in TMD are robust, not mediated by expectation ratings, directl…

Jun 6, 2020 · 8 shares · 131 followers View post →
Andrea Evers
@AndreaEvers · X

RT @Colloca_Luana: Supported by @NIDCR we demonstrated that Placebo effects in TMD are robust, not mediated by expectation ratings, directl…

Jun 6, 2020 · 8 shares · 1,069 followers View post →
Dr. Rachel Louise Cundiff-O'Sullivan (she/her)
@roxyloui · X

RT @Colloca_Luana: Supported by @NIDCR we demonstrated that Placebo effects in TMD are robust, not mediated by expectation ratings, directl…

Jun 5, 2020 · 8 shares · 174 followers View post →
Giacomo Rossettini
@GiacomoRoss86 · X

RT @Colloca_Luana: Supported by @NIDCR we demonstrated that Placebo effects in TMD are robust, not mediated by expectation ratings, directl…

Jun 4, 2020 · 8 shares · 2,881 followers View post →
ɹǝʇlnoԀ pıʌɐᗡ
@Retlouping · X

RT @Colloca_Luana: Supported by @NIDCR we demonstrated that Placebo effects in TMD are robust, not mediated by expectation ratings, directl…

Jun 4, 2020 · 8 shares · 26,291 followers View post →
Josefine
@BirgitG17 · X

RT @Colloca_Luana: Supported by @NIDCR we demonstrated that Placebo effects in TMD are robust, not mediated by expectation ratings, directl…

Jun 4, 2020 · 8 shares · 23 followers View post →
Carlos Gevers
@carlosgeversdc · X

RT @Colloca_Luana: Supported by @NIDCR we demonstrated that Placebo effects in TMD are robust, not mediated by expectation ratings, directl…

Jun 4, 2020 · 8 shares · 796 followers View post →
Luana Colloca
@Colloca_Luana · X

Supported by @NIDCR we demonstrated that Placebo effects in TMD are robust, not mediated by expectation ratings, directly linked to prior therapeutic experiences with an NNT of 1.88 in TMD comparable to anticonvulsants and opioids. https://t.co/ZnFJyXMLih @Colloca_Lab @TMDNoMore https://t.co/f5Sljst2Yb

Jun 4, 2020 · 18 likes · 8 shares · 1,164 followers View post →
Matt Jones
@Mattjones0203 · X

Prior Therapeutic Experiences, Not Expectation Ratings, Predict Placebo Effects: An Experimental Study in Chronic Pain and Healthy Participants https://t.co/A1aWeOiQPj

Jun 4, 2020 · 2 likes · 1,282 followers View post →