BMC Med June 2020 PMID 32493397

The role of testosterone in chronic kidney disease and kidney function in men and women: a bi-directional Mendelian randomization study in the UK Biobank.

Jie V Zhao, C Mary Schooling

Mentions

11
Peak: 4 in Jun 2020
across 2 sources since Jun 2020

Extended reach

63,594
potential audience

Total likes

434

Video views

12,779

Mentions per month

Jun 2020 – Sep 2024

Where it's discussed

  • X / Twitter10 posts
  • YouTube1 videos

AI synopsis

What people are saying

Several discussions highlight the biological link between androgens and CKD, such as animal model findings and genetic analyses, with users engaging through technical comments and references to experimental evidence. The tone varies from scientific interest to speculative remarks, reflecting a nuanced understanding and curiosity about the implications of the research.

AgreementModerate agreement

Most discussions recognize the study's findings linking testosterone to CKD risk, particularly emphasizing the sex-specific effects and animal model support.

InterestModerate interest

The topic of hormonal influence on kidney health sparks moderate interest, with some users discussing potential implications and biological mechanisms.

EngagementModerate engagement

Comments include references to the study's methodology, animal experiments, and broader health implications, showing a moderate level of in-depth discussion.

ImpactModerate impact

There is acknowledgment that these findings could influence future research and clinical approaches to CKD, indicating a recognized potential impact.

Abstract in brief

  • The study used Mendelian randomization to investigate the relationship between genetically predicted testosterone levels and chronic kidney disease (CKD) in men and women, finding that higher bioavailable testosterone increases CKD risk in men but not women.
  • Genetically predicted testosterone was linked to higher hemoglobin and lower HDL cholesterol, consistent with previous clinical trials, but kidney function (eGFR) did not appear to influence testosterone levels.
  • The findings suggest a sex-specific effect of testosterone on kidney health, with implications that biological differences related to reproduction and longevity may influence CKD progression differently in men and women.]

Top posts

Most liked on X and Bluesky
Allie Cox
@AllieLeCroix · X

@TTExulansic See: "The role of testosterone in chronic kidney disease and kidney function in men and women: a bi-directional Mendelian randomization study in the UK Biobank" Her fetish killed her.

Sep 21, 2024 · 21 likes · 83 followers View post →
Enzo Memebriel
@EnzoSuperGabri1 · X

@BakiSorgStorr @LHuxlux @LUKASSH0LE https://t.co/HTrYFIpEpv pues s que tiene impactos

Jun 30, 2024 · 14 likes · 820 followers View post →
Ella Penn
@rhetorical_joke · X

@Ellen_Mingott The healthcare system can only be blamed for using optional, experimental treatments known to cause other damage. "Animal experiments have repeatedly shown that testosterone damages renal function [9, 10]." https://t.co/zxZ1IKhLHC

Aug 19, 2020 · 9 likes · 1 share · 1,895 followers View post →
Herzspitze
@Herzspitze · X

@DocOnco @aktienmessie @Frollein_VogelV Tatsächlich gibt es einen vermuteten Zusammenhang zwischen Androgenen und Progress einer CKD. Albuminurie bzw. Sklerosierung seien unter Androgenen im Tiermodell rasch progredient. https://t.co/a7PH9R8luf

Sep 22, 2024 · 4 likes · 18,931 followers View post →
MR_lit
@Mendelian_lit · X

The role of testosterone in chronic kidney disease and kidney function in men and women: a bi-directional Mendelian randomization study in the UK Biobank. https://t.co/ULJWiWojjL

Jun 5, 2020 · 2 likes · 1,836 followers View post →
J Sam
@JaicSam · X

@precisiondiagn4 @nick_krontiris https://t.co/u4VqJ3lrU8

Nov 6, 2020 · 1 like · 977 followers View post →

All mentions

Herzspitze
@Herzspitze · X

@DocOnco @aktienmessie @Frollein_VogelV Tatsächlich gibt es einen vermuteten Zusammenhang zwischen Androgenen und Progress einer CKD. Albuminurie bzw. Sklerosierung seien unter Androgenen im Tiermodell rasch progredient. https://t.co/a7PH9R8luf

Sep 22, 2024 · 4 likes · 18,931 followers View post →
Allie Cox
@AllieLeCroix · X

@TTExulansic See: "The role of testosterone in chronic kidney disease and kidney function in men and women: a bi-directional Mendelian randomization study in the UK Biobank" Her fetish killed her.

Sep 21, 2024 · 21 likes · 83 followers View post →
Enzo Memebriel
@EnzoSuperGabri1 · X

@BakiSorgStorr @LHuxlux @LUKASSH0LE https://t.co/HTrYFIpEpv pues s que tiene impactos

Jun 30, 2024 · 14 likes · 820 followers View post →
J Sam
@JaicSam · X

@precisiondiagn4 @nick_krontiris https://t.co/u4VqJ3lrU8

Nov 6, 2020 · 1 like · 977 followers View post →
God Zilla
@TrumpsterTrash · X

RT @rhetorical_joke: @Ellen_Mingott The healthcare system can only be blamed for using optional, experimental treatments known to cause oth…

Aug 19, 2020 · 1 share · 6,830 followers View post →
Ella Penn
@rhetorical_joke · X

@Ellen_Mingott The healthcare system can only be blamed for using optional, experimental treatments known to cause other damage. "Animal experiments have repeatedly shown that testosterone damages renal function [9, 10]." https://t.co/zxZ1IKhLHC

Aug 19, 2020 · 9 likes · 1 share · 1,895 followers View post →
MR_lit
@Mendelian_lit · X

The role of testosterone in chronic kidney disease and kidney function in men and women: a bi-directional Mendelian randomization study in the UK Biobank. https://t.co/ULJWiWojjL

Jun 5, 2020 · 2 likes · 1,836 followers View post →
BMC Medicine
@BMCMedicine · X

RT @BMCMedicine: New #OpenAccess research: The role of #testosterone in #chronic kidney #disease and #kidney function in men and women: a b…

Jun 5, 2020 · 2 shares · 9,188 followers View post →
NHS Wales Library Service (NHSWLS)
@WelshHealthLib · X

RT @BMCMedicine: New #OpenAccess research: The role of #testosterone in #chronic kidney #disease and #kidney function in men and women: a b…

Jun 4, 2020 · 2 shares · 1,052 followers View post →
BMC Medicine
@BMCMedicine · X

New #OpenAccess research: The role of #testosterone in #chronic kidney #disease and #kidney function in men and women: a bi-directional #Mendelian #randomization study in the UK Biobank Read it here: https://t.co/cYrEbIYBEX https://t.co/WKpApF5Nsz

Jun 4, 2020 · 2 shares · 9,188 followers View post →