Psychopharmacology (Berl) August 2020 PMID 32500209

Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six phase 2 trials.

Lisa Jerome, Allison A Feduccia, Julie B Wang, Scott Hamilton, Berra Yazar-Klosinski, Amy Emerson, Michael C Mithoefer, Rick Doblin

Mentions

71
Peak: 32 in Jun 2020
across 7 sources since Jun 2020

Extended reach

359,830
potential audience

Total likes

124

Video views

150

Mentions per month

Jun 2020 – Sep 2024

Where it's discussed

  • X / Twitter56 posts
  • News8 articles
  • YouTube2 videos
  • Reddit2 posts
  • Facebook1 posts
  • Instagram1 posts
  • Blogs1 articles

AI synopsis

What people are saying

The discussions are characterized by enthusiastic acknowledgment of the long-term benefits, such as reports that 82% of participants improved and 67% no longer met PTSD criteria, with terminology like 'impressive,' 'promising,' and 'impactful' reflecting strong positive sentiment. The tone and choice of words reveal a high level of engagement and belief that this research could significantly influence PTSD treatment practices.

AgreementModerate agreement

Most discussions support the positive findings and potential of MDMA-assisted psychotherapy for PTSD, reflecting strong agreement with the research.

InterestHigh interest

Posts demonstrate high curiosity, with references to study details, long-term effects, and the significance of results, indicating high interest.

EngagementHigh engagement

Several discussions critically analyze treatment protocols and implications, showing deep engagement with the research outcomes.

ImpactHigh impact

The posts emphasize the groundbreaking nature of the findings, highlighting potential changes in treatment approaches and policy, indicating high impact.

Abstract in brief

  • This study analyzed the long-term effects of MDMA-assisted psychotherapy on individuals with PTSD, showing significant reductions in PTSD symptoms that continued even 12 months after treatment.
  • Participants experienced fewer PTSD diagnoses over time, and most reported benefits like improved relationships and well-being, with few adverse effects.
  • The findings suggest that MDMA-assisted psychotherapy could offer a safe and effective long-term treatment option for PTSD.

Top posts

Most liked on X and Bluesky
Chairman Birb Bernanke
@Bonecondor · X

The federal government needs to decriminalize all schedule 1 drugs https://t.co/4UuqJRuWnc

Nov 4, 2020 · 28 likes · 37,752 followers View post →
Wendy Burn CBE
@wendyburn · X

Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six phase 2 trials | SpringerLink https://t.co/gjnnOwi6Rl

Jun 11, 2020 · 14 likes · 6 shares · 27,284 followers View post →
Nick Pateras
@Nick_Pateras · X

So proud to see the results of @MAPS's Phase II MDMA trials in print in the Psychopharmacology journal as I make my annual donation. If you are just getting interested in #psychedelics, please read the literature. It is important. https://t.co/PsQPEDvQlk https://t.co/6RP81Q1G9E

Jul 14, 2020 · 8 likes · 1 share · 3,312 followers View post →
C̶͚̃a̵̯͠s̸͌͜s̷̜̎ả̵̻n̵̥͑d̸̓ͅr̶̦̽a̵̛̠ Complex̸̗́
@amorvincitomnia · X

@1goodtern Here is longitudinal study on impact of treating PTSD which I infer can apply well to deficient compassion: https://t.co/h3XbeFu3es

Nov 10, 2022 · 8 likes · 2,107 followers View post →
Todd Harrison
@todd_harrison · X

Meanwhile, a few lanes over

Jun 10, 2020 · 7 likes · 69,429 followers View post →
Brian D. Earp, Ph.D.
@briandavidearp · X

Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six phase 2 trials. - Abstract - Europe PMC https://t.co/pQChEnyOgy

Oct 11, 2020 · 6 likes · 4 shares · 26,108 followers View post →

All mentions

Hmmm...
@HmmmNiceee · X

RETRACTION: Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six phase 2 trials We wish to inform the r/science community of an article submitted to the subreddit that has since been retracted by the journal.…

Sep 2, 2024 · 336 followers View post →
Dr. Aryan Sarparast MD
@sarparastmd · X

@chrisaikenmd @PMasand MDMA-AP trial doc here. Few reasons: 1) low dose MDMA seems to be more stimulating than empathogenic, presenting unique challenges 2) there's lotsa active placebo data from phase 1 & 2 trials. The FDA recognizes unblinding is impossible to avoid. https://t.co/R1Q6mXC7tJ

Jun 6, 2024 · 2 likes · 408 followers View post →
Mimi a journey of Synths and Sensibility
@mimidancer · X

@RandomBunnyTalk one more https://t.co/Z2gCFSg6Cv

May 1, 2024 · 1 like · 6,296 followers View post →
Bjørn Holmøy
@HolBjo · X

@N_Gukasyan @MarkLRuffalo Conflating medical ketamine for TRD, often without any accompanying therapy, with all other psychedelic-assisted psychotherapy is misguided. https://t.co/Ft3KF79TPc https://t.co/zaZax6leOr

Oct 1, 2023 · 1 like · 105 followers View post →
Bjørn Holmøy
@HolBjo · X

@MarkLRuffalo The results from MDMA-assisted psychotherapy for PTSD suggests otherwise. Effects tended to increase 12 months after completion. https://t.co/Ft3KF79TPc

Oct 1, 2023 · 105 followers View post →
Gerardo Kleinburg
@gkleinburg · X

@MauVega_Vivas Échale un ojo. Los resultados son impactantes y científicamente controlados. Es un protocolo serio. Saludos cordiales. https://t.co/ICDdzrDTuA

Jul 1, 2023 · 3 likes · 21,007 followers View post →
Jose E. Sánchez Tato
@neurorebelde · X

@TriniGancedo @DrJoaquinMateu https://t.co/r4Qt7Jgofs

Dec 31, 2022 · 1 like · 3,060 followers View post →
C̶͚̃a̵̯͠s̸͌͜s̷̜̎ả̵̻n̵̥͑d̸̓ͅr̶̦̽a̵̛̠ Complex̸̗́
@amorvincitomnia · X

@1goodtern Here is longitudinal study on impact of treating PTSD which I infer can apply well to deficient compassion: https://t.co/h3XbeFu3es

Nov 10, 2022 · 8 likes · 2,107 followers View post →
Nifty☀️
@george2nifty · X

here's the research article that inspired @theburnoutprof's quote

Jun 3, 2022 · 1 like · 613 followers View post →
Paul Silva
@PaulSil01958725 · X

RT @Psychedelic_Med: Because #psychedelicscience has only recently been able to resume, many studies have not observed effects on longer ti…

Jan 2, 2022 · 1 share · 463 followers View post →
Psychedelic Medicine Association
@Psychedelic_Med · X

Because #psychedelicscience has only recently been able to resume, many studies have not observed effects on longer timescales. This longitudinal analysis of #MDMAtherapy for PTSD found symptom improvement for at least a year following treatment. https://t.co/PTHbCtlf8V

Dec 3, 2021 · 4 likes · 1 share · 10,605 followers View post →
Andreas Wahl
@andreas_wahl · X

@joarhalvorsen @jkmjel Det betyr ikke at man ikke har målt effekt over lenger tid; fase-2 studiene indikerer faktisk økt effekt over tid (er det tilfellet for TFP?): "symptom improvement continued at least 12 months post-treatment." https://t.co/wrXjakjm4E

Oct 12, 2021 · 1 like · 758 followers View post →
Thomas Hesslow
@thomashesslow · X

@CoyneoftheRealm This is probably best data as of yet when it comes to longer-term: https://t.co/mSFpYMGFao

Jun 27, 2021 · 306 followers View post →
Anastasie
@Psychanastasie · X

Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six phase 2 trials [Scott Hamilton, Berra Yazar-Klosinski, et al. Psychopharmacology (Berl). 2020; 237(8): 2485–2497.] https://t.co/dkeBf92Mxv https://t.co/mWi5dEerGZ

Jun 7, 2021 · 11,996 followers View post →
Chairman Birb Bernanke
@Bonecondor · X

The federal government needs to decriminalize all schedule 1 drugs https://t.co/4UuqJRuWnc

Nov 4, 2020 · 28 likes · 37,752 followers View post →
market wizard
@JUSTUSnatuhwera · X

RT @briandavidearp: Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of si…

Oct 12, 2020 · 4 shares · 750 followers View post →
Pavel Atanasov
@PavelDAtanasov · X

RT @briandavidearp: Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of si…

Oct 12, 2020 · 4 shares · 1,309 followers View post →
Brian D. Earp, Ph.D.
@briandavidearp · X

RT @briandavidearp: Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of si…

Oct 12, 2020 · 4 shares · 26,108 followers View post →
nicki
@nitpickette · X

RT @briandavidearp: Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of si…

Oct 11, 2020 · 4 shares · 1,718 followers View post →
Brian D. Earp, Ph.D.
@briandavidearp · X

Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six phase 2 trials. - Abstract - Europe PMC https://t.co/pQChEnyOgy

Oct 11, 2020 · 6 likes · 4 shares · 26,108 followers View post →
Shomi Malik
@ShomiMalik · X

RT @Nick_Pateras: So proud to see the results of @MAPS's Phase II MDMA trials in print in the Psychopharmacology journal as I make my annua…

Jul 14, 2020 · 1 share · 156 followers View post →
Nick Pateras
@Nick_Pateras · X

So proud to see the results of @MAPS's Phase II MDMA trials in print in the Psychopharmacology journal as I make my annual donation. If you are just getting interested in #psychedelics, please read the literature. It is important. https://t.co/PsQPEDvQlk https://t.co/6RP81Q1G9E

Jul 14, 2020 · 8 likes · 1 share · 3,312 followers View post →
erica li
@baeocystis · X

@BlusClues_ @Psych_Fin @MAPS paper: https://t.co/NO1V3Tqm28

Jul 10, 2020 · 1 like · 330 followers View post →
jordi ortiz
@jordiortiz50 · X

MDMA-assisted psychotherapy for treatment of Post Traumatic Stress Disorder https://t.co/58AB1uP6KN Original paper https://t.co/e54oqh9QHy

Jul 3, 2020 · 165 followers View post →
Stephen Pimentel
@StephenPiment · X

Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six phase 2 trials https://t.co/AP9Mp2oBM9

Jun 30, 2020 · 2 likes · 12,798 followers View post →
Patrice Chalin
@PatriceChalin · X

RT @Chacruna_net: Long-term follow-up outcomes (>1 year) after the final MDMA-assisted therapy session demonstrated that 82% of participant…

Jun 19, 2020 · 7 shares · 50 followers View post →
Holy Psychedelics!
@sebgaete · X

RT @Chacruna_net: Long-term follow-up outcomes (>1 year) after the final MDMA-assisted therapy session demonstrated that 82% of participant…

Jun 15, 2020 · 7 shares · 781 followers View post →
LapisPhilosoforum
@ShamanofDrums · X

RT @Chacruna_net: Long-term follow-up outcomes (>1 year) after the final MDMA-assisted therapy session demonstrated that 82% of participant…

Jun 15, 2020 · 7 shares · 2,472 followers View post →
Pádraig
@padraigcarroll · X

#MDMA Cures 67% of people with #PTSD, measured > 12 months after treatment !!! https://t.co/FW8BQ4qKqM

Jun 15, 2020 · 2 likes · 907 followers View post →
S t i c k y ✨
@Sticky333Love · X

RT @Chacruna_net: Long-term follow-up outcomes (>1 year) after the final MDMA-assisted therapy session demonstrated that 82% of participant…

Jun 15, 2020 · 7 shares · 403 followers View post →
Cooper
@CooperMcDevitt · X

RT @PsydelicsToday: Long-term Follow-Up Outcomes of MDMA-assisted Psychotherapy for Treatment of PTSD: A Longitudinal Pooled Analysis of Si…

Jun 14, 2020 · 2 shares · 367 followers View post →
ENTHEOCUREAN
@entheocurean · X

RT @Chacruna_net: Long-term follow-up outcomes (>1 year) after the final MDMA-assisted therapy session demonstrated that 82% of participant…

Jun 14, 2020 · 7 shares · 488 followers View post →
Shakti Kaa
@Shaktikaa · X

RT @Chacruna_net: Long-term follow-up outcomes (>1 year) after the final MDMA-assisted therapy session demonstrated that 82% of participant…

Jun 14, 2020 · 7 shares · 613 followers View post →
Chacruna Institute
@Chacruna_Inst · X

Long-term follow-up outcomes (>1 year) after the final MDMA-assisted therapy session demonstrated that 82% of participants exhibited clinically significant PTSD symptom improvement, while 67% of participants no longer met diagnostic criteria for PTSD. https://t.co/UtNg2BZekh https://t.co/Lw7uCJg0Il

Jun 14, 2020 · 5 likes · 7 shares · 12,581 followers View post →
LionAndDevil
@BeatsNotBombz · X

https://t.co/cuZuG3Q3o1

Jun 14, 2020 · 748 followers View post →
TJ, #FullMetaJacket
@coristus · X

RT @PsydelicsToday: Long-term Follow-Up Outcomes of MDMA-assisted Psychotherapy for Treatment of PTSD: A Longitudinal Pooled Analysis of Si…

Jun 13, 2020 · 2 shares · 2,426 followers View post →
28/09 ¿?
@thubenzimande · X

RT @PsydelicsToday: Long-term Follow-Up Outcomes of MDMA-assisted Psychotherapy for Treatment of PTSD: A Longitudinal Pooled Analysis of Si…

Jun 13, 2020 · 2 shares · 270 followers View post →
Psychedelics Today
@PsydelicsToday · X

Long-term Follow-Up Outcomes of MDMA-assisted Psychotherapy for Treatment of PTSD: A Longitudinal Pooled Analysis of Six Phase 2 Trials https://t.co/Q1hmBO2JLZ

Jun 13, 2020 · 4 likes · 2 shares · 41,620 followers View post →
bluedot1
@bluedot113 · X

RT @BeckleyResearch: The most comprehensive analysis yet of the safety & durability of treatment outcomes following #MDMA-assisted psychoth…

Jun 11, 2020 · 4 shares · 33 followers View post →
Dr Miriam Zikry
@Miriamzikry · X

RT @wendyburn: Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six pha…

Jun 11, 2020 · 6 shares · 1,321 followers View post →
V¡B€S
@VBS710 · X

RT @BeckleyResearch: The most comprehensive analysis yet of the safety & durability of treatment outcomes following #MDMA-assisted psychoth…

Jun 11, 2020 · 4 shares · 7 followers View post →
Thinking Clearly
@ThinkingKlearly · X

RT @BeckleyResearch: The most comprehensive analysis yet of the safety & durability of treatment outcomes following #MDMA-assisted psychoth…

Jun 11, 2020 · 4 shares · 2,938 followers View post →
Choose Psychiatry
@Choose_Psych · X

RT @wendyburn: Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six pha…

Jun 11, 2020 · 6 shares · 6,399 followers View post →
Benjamin Geers
@BenjaminGeers · X

RT @wendyburn: Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six pha…

Jun 11, 2020 · 6 shares · 511 followers View post →
JJ
@JJ_Hartford · X

RT @wendyburn: Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six pha…

Jun 11, 2020 · 6 shares · 149 followers View post →
Wendy Burn CBE
@wendyburn · X

Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six phase 2 trials | SpringerLink https://t.co/gjnnOwi6Rl

Jun 11, 2020 · 14 likes · 6 shares · 27,284 followers View post →
Don Bertoldo
@ricardelico · X

@Horacio_Staines El enlace es al foro en reddit/r/science donde se presentan y comentan investigaciones. A su vez enlaza al artículo en prensa popular (en alemán). Si quieres echarte un clavado a los detalles, tienes que dar con el "paper" publicado en Psychopharmacology https://t.co/bKMWG9slKg

Jun 11, 2020 · 1,974 followers View post →
Koemgun
@koemgun · X

Le MDMA (ecstasy) serait utile avec une psychothérapie pour les gens ayant du stress post traumatique. Alors il y a pas de groupe contrôle mais ...97% d'amélioration plus ou moins durable c'est juste ouf comme effet. Enfin sauf erreur de ma part ^^ https://t.co/39cmY2iErS

Jun 11, 2020 · 225 followers View post →
Don Bertoldo
@ricardelico · X

Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six phase 2 trials El estudio o "paper" publicado en Psychopharmacology 4-jun-2020 https://t.co/5CEDYluQ9Z

Jun 11, 2020 · 1,974 followers View post →
Thomas Hesslow
@thomashesslow · X

Då snackar alltså om en "kort" behandling: tio terapisamtal plus två längre MDMA-sessioner. Även vid kronisk PTSD. Imponerande! Behandlingen kräver två terapeuter hela vägen igenom, så det kommer kosta en del när det väl rullas ut i vården inom 3-4 år. https://t.co/2mTCg5AqSc

Jun 10, 2020 · 2 likes · 306 followers View post →
Todd Harrison
@todd_harrison · X

Meanwhile, a few lanes over

Jun 10, 2020 · 7 likes · 69,429 followers View post →
lisa witham
@cheezwitham · X

Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six phase 2 trials | SpringerLink https://t.co/hY8qQGEv5i

Jun 10, 2020 · 9,305 followers View post →
Harsh Taneja
@harshtan · X

RT @MichaelHaichin: Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: analysis of six phase 2 trials "The…

Jun 9, 2020 · 2 shares · 328 followers View post →
Michael Haichin
@MichaelHaichin · X

Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: analysis of six phase 2 trials "The number of participants who no longer met PTSD criteria increased from treatment exit (56.0%) to long-term follow-up (67.0%)." https://t.co/MaszSIUq5e

Jun 9, 2020 · 6 likes · 2 shares · 3,715 followers View post →
Tanya Saraiya, PhD
@DrTanyaSaraiya · X

MDMA assisted psychotherapy reduces PTSD https://t.co/rHVsuWqoc9

Jun 9, 2020 · 628 followers View post →
Marco Niello
@MarcoNiello · X

Promising results from the Long-term Follow-Up Outcomes of MDMA-assisted Psychotherapy for the Treatment of PTSD! https://t.co/oHKcXZb3Bh

Jun 8, 2020 · 6 likes · 374 followers View post →
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