Results of my F32 fellowship were published online in @HyperAHA yesterday | Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy Humans https://t.co/I93UdzIC5u @kdinbburg @Abigail_Casso
Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy Humans.
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Jun 2020 – Sep 2020Where it's discussed
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X / Twitter21 posts
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News14 articles
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Blogs6 articles
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Reddit3 posts
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What people are saying
Overall, the group shows a balanced perspective, with many acknowledging the research's potential implications, such as links between gut bacteria and vascular health, supported by phrases like 'damage our arteries' and 'promotes age-related stress.' While some discussions reflect skepticism with statements like 'the jury is still out,' the tone remains engaged and curious, demonstrating recognition of the importance of the findings without complete certainty.
Most discussions acknowledge the findings and seem to support the idea that TMAO is linked to vascular aging, though some remain cautious, emphasizing the need for more evidence.
The discussions show a moderate level of curiosity, with mentions of related research and potential health implications, indicating genuine interest.
Participants reference specific studies, comment on the mechanisms, and share personal or related experiences, reflecting a moderate level of engagement.
The discussions recognize the significance of the research, but many also highlight ongoing debates and future research needs, indicating a neutral impact level.
Abstract in brief
- The study finds that trimethylamineN-oxide (TMAO), a metabolite generated by gut bacteria, increases with age in both humans and mice, and higher levels are linked to impaired blood vessel function and increased oxidative stress.
- In mice, supplementing with TMAO causes aging-like damage to blood vessels, reducing their ability to dilate properly, increasing oxidative stress markers, and impairing nitric oxide signaling; these effects can be reversed with antioxidants.
- In humans, middle-aged and older adults with higher TMAO levels show greater signs of oxidative stress in their endothelial cells, but antioxidant treatments can improve blood vessel function, suggesting TMAO plays a role in age-related vascular decline.
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Most liked on X and BlueskyTMAO promotes age-related vascular oxidative stress and endothelial dysfunction in mice and healthy humans. https://t.co/SUF559BGRr https://t.co/3FEFWjRLHq
Yep. Something like that. https://t.co/ULtUAalYBU https://t.co/scZ423hvKZ
@AviBittMD some more TMAO data for you https://t.co/A0JQyohB8j
Trimethylamine-n-oxide promotes age-related vascular oxidative stress and endothelial dysfunction in mice and health... - Brunt VE et al. - https://t.co/LGNCKxOTnz #microbiome
TMAO - CVD Uni of Boulder Colorado study Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy Humans https://t.co/eKJCMTGgmW https://t.co/iPSY4aGGyA https://t.co/HOzJfP1p6B seems to agree with Hazen lab theory
All mentions
TMAO and Its Impact on Vascular Health and Aging Processes
This video explains TMAO, a metabolite from gut bacteria, its increasing levels with age, and its link to vascular impairment, oxidative stress, and endothelial dysfunction, with insights from studies in both mice and…
Impact of TMAO on Aging and Vascular Health Explained by a Medical Expert
Ol Me chamo Matheus Donadel sou Mdico CREMERS 47207 e falo sobre envelhecimento saudavel e preveno de doenas como ter uma vida mais longa viver mais tempo e como dentro desse tempo ter o maximo de sade possvel Descubra…
On the other hand, the jury is still out. Opposing evidence presented here: https://t.co/M0YmghzXHz We need to careful to to overweigh any one publication and always err on the side of caution ( for example, also in lipidology debates).
@bioMioSoftware @nick_krontiris @PrimaryCarePAC @MatthewJDalby Just remember, much of this is theory, and the jury is still out. The ultimate verdict may go either way. For example, just published: https://t.co/M0YmghzXHz
TMAO promotes age-related vascular oxidative stress and endothelial dysfunction in mice and healthy humans. https://t.co/SUF559BGRr https://t.co/3FEFWjRLHq
Yep. Something like that. https://t.co/ULtUAalYBU https://t.co/scZ423hvKZ
Já ho snad už ani nemam, nízký tlak :-)) https://t.co/ykYMgxzGFP prostřednictvím @YouTube
@ScepticalDoctor Yes. And in cell culture. https://t.co/82yb7Uscs3 https://t.co/20sh2eWGhM
A compound produced in the #gut when we eat #redmeat damages our arteries and may play a key role in boosting the risk of #heartdisease as we get older, according to new research. Reference: https://t.co/EAi1fcJ9jM https://t.co/l1mkfZhQCk
Hypertension:肠道微生物产生的化合物会损伤动脉,进而增加患心脏病的风险。 https://t.co/hm8zCkXmR8
TMAO - CVD Uni of Boulder Colorado study Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy Humans https://t.co/eKJCMTGgmW https://t.co/iPSY4aGGyA https://t.co/HOzJfP1p6B seems to agree with Hazen lab theory
@AviBittMD some more TMAO data for you https://t.co/A0JQyohB8j
RT @GMFHx: Are gut bacteria linked to the ageing of arteries? TMAO produced in the gut when we eat red meat damages our arteries and may pl…
RT @GMFHx: Are gut bacteria linked to the ageing of arteries? TMAO produced in the gut when we eat red meat damages our arteries and may pl…
RT @GMFHx: Are gut bacteria linked to the ageing of arteries? TMAO produced in the gut when we eat red meat damages our arteries and may pl…
RT @GMFHx: Are gut bacteria linked to the ageing of arteries? TMAO produced in the gut when we eat red meat damages our arteries and may pl…
TMAO is related to ageing of blood vessels https://t.co/cvV2PUhNuH
RT @viennabrunt: Results of my F32 fellowship were published online in @HyperAHA yesterday | Trimethylamine-N-Oxide Promotes Age-Related Va…
RT @viennabrunt: Results of my F32 fellowship were published online in @HyperAHA yesterday | Trimethylamine-N-Oxide Promotes Age-Related Va…
RT @viennabrunt: Results of my F32 fellowship were published online in @HyperAHA yesterday | Trimethylamine-N-Oxide Promotes Age-Related Va…
Results of my F32 fellowship were published online in @HyperAHA yesterday | Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy Humans https://t.co/I93UdzIC5u @kdinbburg @Abigail_Casso
Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy Humans. https://t.co/b5pvD911hG
Trimethylamine-n-oxide promotes age-related vascular oxidative stress and endothelial dysfunction in mice and health... - Brunt VE et al. - https://t.co/LGNCKxOTnz #microbiome
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