The overall tone underscores a consensus on the necessity of detailed diagnostic criteria and standardized reporting, as seen in statements like 'simply noting a diagnosis of CP is not enough' and calls for uniform definitions, implying the review's findings could considerably influence future research and clinical practice.
AgreementModerate agreement
Most discussions emphasize the importance of standardizing the definition and diagnosis of cerebral palsy, indicating moderate to strong agreement with the review's findings.
InterestHigh interest
The posts show high interest, focusing on improving research standards and treatment implications, with multiple references to the need for precise definitions.
EngagementModerate engagement
Participants engage actively by referencing specific aspects like case documentation, diagnostic criteria, and potential therapies, demonstrating meaningful involvement.
ImpactModerate impact
The discussions suggest that the review could influence research practices and clinical approaches, emphasizing the significance of standardized definitions for advancing knowledge and treatment.
Abstract in brief
This systematic review examined 57 genetic studies of cerebral palsy (CP) published between 1990 and 2019 to assess how well they defined CP and reported case details, with only 32% following international guidelines.
Many studies lacked complete or clear descriptions of how they diagnosed and classified CP, making it difficult to compare findings or ensure accurate diagnosis across research.
The review highlights the need for better adherence to standardized guidelines, like those from SCPE, to improve the quality, consistency, and usefulness of genetic research in CP, ultimately aiding gene discovery efforts.]
Could not agree more. We need to uniformly apply #cerebralpalsy consensus definitions to do any meaningful research...or provide appropriate patient care. https://t.co/qyy0CDlIOp
Aug 3, 2020 · 6 likes · 1 share · 1,627 followersView post →
MP
Mac Keith Press
@mackeithpress · X
How should #cerebralpalsy be defined to conduct useful #genetic research?
@bwmol @GeczSquadGoals @neurogeneration @PalmerLyle
https://t.co/M92MjjL41i
Aug 10, 2020 · 5 likes · 3 shares · 2,062 followersView post →
BD
Bernard Dan
@ProfBernardDan · X
The authors of this #systematicreview of #genetic studies of #cerebralpalsy urge researchers to report in detail the case definition and ascertainment method to aid standardization of diagnostic criteria, minimize study heterogeneity and enable comparisons https://t.co/Grm4fraz3Z https://t.co/WUM1yZMzqv
Nov 26, 2020 · 4 likes · 2 shares · 1,704 followersView post →
BD
Bernard Dan
@ProfBernardDan · X
@Marilynpaedsahp @EACDtweet https://t.co/Grm4fraz3Z
https://t.co/zTzsJEHQIO
https://t.co/2onxEbp7Qb
"When molecular/cellular mechanisms that lead to CP are understood, this knowledge can be used to develop effective new therapies seeking to control symptoms and treat the fundamental pathophysiology of CP"
Nov 27, 2020 · 1 like · 1,704 followersView post →
MP
Mac Keith Press
@mackeithpress · X
#DMCN podcast
Definition and diagnosis of #cerebralpalsy in #genetic studies: a #SystematicReview
https://t.co/k4ynZSjY0a
Aug 20, 2020 · 2 shares · 2,062 followersView post →
MP
Mac Keith Press
@mackeithpress · X
RT @ProfBernardDan: The authors of this #systematicreview of #genetic studies of #cerebralpalsy urge researchers to report in detail the ca…
Nov 27, 2020 · 2 shares · 2,062 followersView post →
This systematic review analyzed 57 genetic studies of cerebral palsy to assess how well they defined and diagnosed CP. It highlights the importance of adhering to international guidelines for better consistency and…
This video explores the challenges faced by disabled children and their families during the COVID-19 pandemic, with insights from an AACPDM perspective, highlighting long-term impacts and strategies for support.
RT @ProfBernardDan: The authors of this #systematicreview of #genetic studies of #cerebralpalsy urge researchers to report in detail the ca…
Nov 28, 2020 · 2 shares · 314 followersView post →
BD
Bernard Dan
@ProfBernardDan · X
@Marilynpaedsahp @EACDtweet https://t.co/Grm4fraz3Z
https://t.co/zTzsJEHQIO
https://t.co/2onxEbp7Qb
"When molecular/cellular mechanisms that lead to CP are understood, this knowledge can be used to develop effective new therapies seeking to control symptoms and treat the fundamental pathophysiology of CP"
Nov 27, 2020 · 1 like · 1,704 followersView post →
MP
Mac Keith Press
@mackeithpress · X
RT @ProfBernardDan: The authors of this #systematicreview of #genetic studies of #cerebralpalsy urge researchers to report in detail the ca…
Nov 27, 2020 · 2 shares · 2,062 followersView post →
BD
Bernard Dan
@ProfBernardDan · X
The authors of this #systematicreview of #genetic studies of #cerebralpalsy urge researchers to report in detail the case definition and ascertainment method to aid standardization of diagnostic criteria, minimize study heterogeneity and enable comparisons https://t.co/Grm4fraz3Z https://t.co/WUM1yZMzqv
Nov 26, 2020 · 4 likes · 2 shares · 1,704 followersView post →
DB
dystobot (broken)
@dystobot_broken · X
RT @drbhooma: What should be the standard for defining CP in research articles looking at etiologies? Great paper on this : https://t.co/qy…
What should be the standard for defining CP in research articles looking at etiologies? Great paper on this : https://t.co/qyy0CD47WR In short, simply noting a dx of CP is not enough - should have clear documentation of non-progressive motor disability + spasticty/#dystonia/etc.
How should #cerebralpalsy be defined to conduct useful #genetic research?
@bwmol @GeczSquadGoals @neurogeneration @PalmerLyle
https://t.co/M92MjjL41i
Aug 10, 2020 · 5 likes · 3 shares · 2,062 followersView post →
CF
C. Roy Lin, MD, MPH, FAAN
@RoyCLinMD · X
RT @drbhooma: Could not agree more. We need to uniformly apply #cerebralpalsy consensus definitions to do any meaningful research...or prov…
Aug 3, 2020 · 1 share · 1,618 followersView post →
BD
Bhooma Aravamuthan MD DPhil
@drbhooma · X
Could not agree more. We need to uniformly apply #cerebralpalsy consensus definitions to do any meaningful research...or provide appropriate patient care. https://t.co/qyy0CDlIOp
Aug 3, 2020 · 6 likes · 1 share · 1,627 followersView post →
N
Rana Et Al (2022) | PDF | Physical Therapy | Statistics
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... 10.1111/dmcn.14585 cross-sectional study. Journal of clinical and diagnostic research: 25. Martakis, K., Stark, C., Rehberg, M., Semler, O., Duran, I., &
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