Curr Obes Rep September 2020 PMID 32632847

Autoantibody Production in Obesity: Is There Evidence for a Link Between Obesity and Autoimmunity?

Christina Tsigalou, Natalia Vallianou, Maria Dalamaga

Full text PDF Download social card

Mentions

Peak: 1 in Jul 2020

across 3 sources since Jul 2020

Extended reach

9,510

potential audience

Total likes

149

Video views

1,638

Mentions per month

Jul 2020 – Dec 2024

Where it's discussed

News3 articles
X / Twitter2 posts
YouTube2 videos

AI synopsis

What people are saying

The discussions reflect a recognition of the connection between obesity and autoimmune risks, with comments such as 'Overgewicht kan auto-immuun tot gevolg hebben,' which straightforwardly affirms the link, and directives like 'Lees eens wat,' indicating an interest in exploring the topic further. Tone and word choices are direct and suggest a general curiosity rather than critical debate, leading to moderate scores across all dimensions.

AgreementModerate agreement

Most discussions acknowledge the potential link between obesity and autoimmunity, suggesting general agreement with the publication's premise.

InterestModerate interest

Participants seem somewhat curious about the topic, reflected in brief comments and recommendations to read or consider the research.

EngagementNeutral engagement

The engagement appears moderate, limited to sharing opinions or encouraging others to explore the article further without deep technical discussion.

ImpactModerate impact

The conversations have a modest impact, mainly raising awareness rather than challenging or transforming existing understanding or practices.

Abstract in brief

This review explores the increasing connection between obesity and autoimmune diseases, focusing on how adipose tissue influences immune function through adipokines and inflammatory cytokines, which can impair B cell activity and autoantibody production.
Obesity is linked to a higher risk and severity of various autoimmune conditions like rheumatoid arthritis, multiple sclerosis, and Hashimoto's thyroiditis, and it can also lead to increased levels of inflammatory markers like leptin, resistin, and visfatin.
The presence of obesity can weaken the body's self-tolerance mechanisms by promoting pro-inflammatory processes, reducing regulatory immune cells, and increasing pro-inflammatory T helper cells, thereby creating conditions favorable for autoimmune autoantibody production; however, more research is needed to fully understand these mechanisms and develop targeted treatments.

Read the full abstract

All mentions

Differences Between Type 1 and Type 2 Diabetes Explained Clearly

This video explains the key diagnostic criteria and differences between type 1 and type 2 diabetes, helping viewers understand these common conditions and distinguish between them for accurate diagnosis and management.

Dra Janaina Koenen · Nov 17, 2022 1,599 views

Lifestyle Interventions for Managing Autoimmune Diseases

In this episode, Miles Hassel, MD discusses how lifestyle interventions can manage autoimmune diseases. Key areas include maintaining a healthy waistline, sunlight exposure for Vitamin D, adequate sleep for immune…

GreatMed · Jun 27, 2024 39 views

Myriam

@myriam_vhj · X

@SandraZuidema Andersom Overgewicht kan auto-immuun tot gevolg hebben Lees eens wat https://t.co/spZYDhI9JN

Dec 22, 2024 · 6 likes · 5,415 followers View post →

Adipose Papers

@adipose_papers · X

Autoantibody Production in Obesity: Is There Evidence for a Link Between Obesity and Autoimmunity? https://t.co/y3K8pcIHpq https://t.co/LXoMim7QQb

Jul 8, 2020 · 2,457 followers View post →