PubHawk
Cancer Med September 2020 PMID 32717139

Insulin-like growth factor-1 and site-specific cancers: A Mendelian randomization study.

Susanna C Larsson, Paul Carter, Mathew Vithayathil, Siddhartha Kar, Amy M Mason, Stephen Burgess

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Mentions

76
Peak: 12 in Nov 2025
across 6 sources since Jul 2020

Extended reach

9,446
potential audience

Total likes

41

Video views

329

Mentions per month

Jul 2020 – Dec 2025

Where it's discussed

  • TikTok42 posts
  • Facebook13 posts
  • X / Twitter7 posts
  • Instagram7 posts
  • News5 articles
  • YouTube2 videos

AI synopsis

What people are saying

Participants express strong support for the study’s conclusions, emphasizing its importance in understanding cancer risk, as seen in posts mentioning 'causal association' and 'supporting a causal link.' The tone is confident and focused on the potential implications for cancer prevention and research, reflecting deep engagement and recognition of the study’s significance.

AgreementStrong agreement

Most discussions support the study’s findings by highlighting its evidence of a causal link between IGF-1 levels and certain cancers, especially colorectal and prostate.

InterestModerate interest

There is moderate interest shown, with participants focusing on the implications for cancer risk and mentioning specific cancers, but some comments are brief.

EngagementHigh engagement

Discussions include references to the research methods and potential impacts, indicating deep engagement with the scientific implications.

ImpactHigh impact

Participants see this research as highly impactful for understanding cancer risks and possibly influencing future studies or clinical approaches.

Abstract in brief

  • The study used genetic data to explore whether higher levels of insulin-like growth factor 1 (IGF1) are causally linked to different types of cancer, focusing on prostate, breast, ovarian, lung, and other site-specific cancers.
  • It found some evidence that higher IGF1 levels might increase the risk of colorectal cancer and prostate cancer, but there was no clear link for breast cancer or the other 14 cancers examined.
  • Overall, the results suggest a potential causal relationship between IGF1 and certain cancers, particularly colorectal and prostate, but more research is needed to confirm these findings for other cancer types.
Read the full abstract

Top posts

Most liked on X and Bluesky
Susanna Larsson
@LarssonSC · X

Our Mendelian randomization study supports a causal association between elevated IGF-1 levels and increased risk of colorectal cancer https://t.co/UiKaOFVMgV @amymariemason @stevesphd

Jul 28, 2020 · 9 likes · 3 shares · 289 followers View post →
MR_lit
@Mendelian_lit · X

Insulin-like growth factor-1 and site-specific cancers: A Mendelian randomization study. https://t.co/FqkaSfgMlO

Jul 28, 2020 · 1 like · 1 share · 1,836 followers View post →
Stephen Burgess
@stevesphd · X

RT @LarssonSC: Our Mendelian randomization study supports a causal association between elevated IGF-1 levels and increased risk of colorect…

Jul 28, 2020 · 3 shares · 2,514 followers View post →
Sarah Lewis
@ProfSarahJLewis · X

RT @Mendelian_lit: Insulin-like growth factor-1 and site-specific cancers: A Mendelian randomization study. https://t.co/FqkaSfgMlO

Jul 28, 2020 · 1 share · 1,331 followers View post →
Siddhartha Kar
@siddhartha_kar · X

RT @LarssonSC: Our Mendelian randomization study supports a causal association between elevated IGF-1 levels and increased risk of colorect…

Jul 28, 2020 · 3 shares · 1,034 followers View post →
Paperbirds_Oncology
@PaperbirdsO · X

New article: Insulin-like growth factor-1 and site-specific cancers: A Mendelian randomization study. https://t.co/4TlRkUt9az #prostatecancer #oncology https://t.co/XJsKrCUl66

Jul 28, 2020 · 891 followers View post →

All mentions

Siddhartha Kar
@siddhartha_kar · X

RT @LarssonSC: Our Mendelian randomization study supports a causal association between elevated IGF-1 levels and increased risk of colorect…

Jul 28, 2020 · 3 shares · 1,034 followers View post →
Amy Mason
@amymariemason · X

RT @LarssonSC: Our Mendelian randomization study supports a causal association between elevated IGF-1 levels and increased risk of colorect…

Jul 28, 2020 · 3 shares · 525 followers View post →
Stephen Burgess
@stevesphd · X

RT @LarssonSC: Our Mendelian randomization study supports a causal association between elevated IGF-1 levels and increased risk of colorect…

Jul 28, 2020 · 3 shares · 2,514 followers View post →
Susanna Larsson
@LarssonSC · X

Our Mendelian randomization study supports a causal association between elevated IGF-1 levels and increased risk of colorectal cancer https://t.co/UiKaOFVMgV @amymariemason @stevesphd

Jul 28, 2020 · 9 likes · 3 shares · 289 followers View post →
Sarah Lewis
@ProfSarahJLewis · X

RT @Mendelian_lit: Insulin-like growth factor-1 and site-specific cancers: A Mendelian randomization study. https://t.co/FqkaSfgMlO

Jul 28, 2020 · 1 share · 1,331 followers View post →
MR_lit
@Mendelian_lit · X

Insulin-like growth factor-1 and site-specific cancers: A Mendelian randomization study. https://t.co/FqkaSfgMlO

Jul 28, 2020 · 1 like · 1 share · 1,836 followers View post →
Paperbirds_Oncology
@PaperbirdsO · X

New article: Insulin-like growth factor-1 and site-specific cancers: A Mendelian randomization study. https://t.co/4TlRkUt9az #prostatecancer #oncology https://t.co/XJsKrCUl66

Jul 28, 2020 · 891 followers View post →
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